| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | C. H. Heldin | |
| A. Ostman | |||
| L. Rönnstrand | |||
| P2860 | cites work | GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit | Q24292767 |
| Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction | Q24303984 | ||
| Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes | Q24306447 | ||
| Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro | Q24306912 | ||
| Human growth hormone and extracellular domain of its receptor: crystal structure of the complex | Q24308045 | ||
| Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction | Q24308600 | ||
| The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp | Q24310396 | ||
| Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor | Q24311075 | ||
| Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor | Q24311900 | ||
| Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains | Q24315001 | ||
| The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors | Q24320101 | ||
| Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors | Q24322730 | ||
| Both homodimeric isoforms of PDGF (AA and BB) have mitogenic and chemotactic activity and stimulate phosphoinositol turnover | Q42796011 | ||
| Inhibition of PDGF receptor binding and PDGF-stimulated biological activity in vitro and of intimal lesion formation in vivo by 2-bromomethyl-5-chlorobenzene sulfonylphthalimide | Q42796117 | ||
| Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation | Q42796185 | ||
| Dissociation of tyrosine phosphorylation and activation of phosphoinositide phospholipase C induced by the protein kinase C inhibitor Ro-31-8220 in Swiss 3T3 cells treated with platelet-derived growth factor | Q42800552 | ||
| The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C. | Q42802927 | ||
| Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens | Q42805681 | ||
| v-Src activates a unique phospholipase D activity that can be distinguished from the phospholipase D activity activated by phorbol esters | Q42806427 | ||
| Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis | Q42807111 | ||
| Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation | Q42807654 | ||
| Activation of platelet-derived growth factor (PDGF) receptor dephosphorylation in intact Swiss 3T3 cells by elevators of intracellular Ca2+ and cAMP. | Q42810105 | ||
| Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins | Q42812895 | ||
| Production of PDGF-like growth factor by breast cancer cell lines | Q42814637 | ||
| Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin | Q42815043 | ||
| Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src. | Q42820354 | ||
| Platelet-derived growth factor elicits cyclic AMP accumulation in swiss 3T3 cells: Role of prostaglandin production | Q42822965 | ||
| PDGF receptor as a specific in vivo target for low M(r) phosphotyrosine protein phosphatase | Q42824305 | ||
| Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase | Q42828607 | ||
| An essential role for Rac in Ras transformation | Q42829150 | ||
| Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains | Q42832186 | ||
| PDGF-induced phosphorylation of Tyr28 in the N-terminus of Fyn affects Fyn activation. | Q42833254 | ||
| Phospholipase D activation by the mitogens platelet-derived growth factor and 12-O-tetradecanoylphorbol 13-acetate in NIH-3T3 cells | Q42834439 | ||
| Inhibition of cellular response to platelet-derived growth factor by low M(r) phosphotyrosine protein phosphatase overexpression. | Q42835308 | ||
| Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation | Q44763188 | ||
| The platelet-derived growth factor isomers, PDGF-AA, PDGF-AB and PDGF-BB, induce contraction of vascular smooth muscle cells by different intracellular mechanisms | Q45054989 | ||
| Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus | Q45798186 | ||
| Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor | Q45798365 | ||
| Antisense oligonucleotide inhibition of PDGFR-beta receptor subunit expression directs suppression of intimal thickening | Q45880557 | ||
| Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells | Q46243548 | ||
| Beta PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells | Q46452809 | ||
| PDGF AA homodimers are potent chemoattractants for fibroblasts and neutrophils, and for monocytes activated by lymphocytes or cytokines | Q46764238 | ||
| The MAPK signaling cascade | Q28292599 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal | Q28297924 | ||
| Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 | ||
| Tyrosine phosphorylation of p130(cas) by bombesin, lysophosphatidic acid, phorbol esters, and platelet-derived growth factor. Signaling pathways and formation of a p130(cas)-Crk complex | Q28507631 | ||
| Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors | Q28513453 | ||
| Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation | Q28609129 | ||
| Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases | Q28609156 | ||
| Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule | Q28609946 | ||
| Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro | Q28625928 | ||
| Role of phosphatidylinositol kinase in PDGF receptor signal transduction | Q28645684 | ||
| Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types | Q28645713 | ||
| Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1 | Q28645716 | ||
| Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins | Q28645718 | ||
| A role for Src in signal relay by the platelet-derived growth factor alpha receptor | Q28645730 | ||
| Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B | Q28646376 | ||
| STATs and gene regulation | Q29547796 | ||
| The pathogenesis of atherosclerosis: a perspective for the 1990s | Q29547827 | ||
| Integrins and signal transduction pathways: the road taken | Q29547895 | ||
| Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
| An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1 | Q29614256 | ||
| Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice | Q29615196 | ||
| Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors | Q29616545 | ||
| Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice | Q29617498 | ||
| Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases | Q29618331 | ||
| The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase | Q29618387 | ||
| Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction | Q29618388 | ||
| Phosphatidylinositol-3-OH kinase as a direct target of Ras | Q29620177 | ||
| Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesis | Q30176334 | ||
| Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling | Q30176570 | ||
| Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G. | Q30176600 | ||
| The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding | Q30176665 | ||
| SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction. | Q30176904 | ||
| Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. | Q30176960 | ||
| Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin | Q30195270 | ||
| Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex | Q30450356 | ||
| Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate | Q30464735 | ||
| Evidence for "response to injury" hypothesis | Q33484767 | ||
| Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities | Q33491173 | ||
| Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. | Q33491174 | ||
| Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase | Q33604834 | ||
| A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein | Q33885920 | ||
| Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF | Q33887469 | ||
| cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells | Q34038049 | ||
| Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation | Q34133504 | ||
| Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques | Q34218450 | ||
| RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class | Q34308033 | ||
| Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation | Q34340175 | ||
| An Antibody Reactive with Domain 4 of the Platelet-derived Growth Factor β Receptor Allows BB Binding while Inhibiting Proliferation by Impairing Receptor Dimerization | Q34431480 | ||
| Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor | Q34684084 | ||
| Ras signalling and apoptosis | Q34746668 | ||
| Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein | Q35256418 | ||
| Platelet-derived growth factor receptors on macrovascular endothelial cells mediate relaxation via nitric oxide in rat aorta | Q35599183 | ||
| Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein | Q35895171 | ||
| Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB | Q36051073 | ||
| Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development | Q36074211 | ||
| Induction of platelet-derived growth factor receptor expression in smooth muscle cells and fibroblasts upon tissue culturing. | Q36219663 | ||
| Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown | Q36232499 | ||
| Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices | Q36232788 | ||
| Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction | Q36235805 | ||
| The chemotactic response to PDGF-BB: evidence of a role for Ras. | Q36235836 | ||
| Extracellular matrix alters PDGF regulation of fibroblast integrins | Q36236430 | ||
| Anchorage-dependent cell cycle progression | Q36254508 | ||
| Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors | Q36382363 | ||
| Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. | Q36382612 | ||
| The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells | Q36485178 | ||
| The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1 | Q36551325 | ||
| Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation | Q36552522 | ||
| Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation | Q36556010 | ||
| Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity | Q36563209 | ||
| Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation | Q36564274 | ||
| Analysis of mutant platelet-derived growth factor receptors expressed in PC12 cells identifies signals governing sodium channel induction during neuronal differentiation | Q36564624 | ||
| Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways | Q36564768 | ||
| Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. | Q36566823 | ||
| Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap | Q36567460 | ||
| A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase | Q36643931 | ||
| Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively | Q36658598 | ||
| Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta | Q36667470 | ||
| The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation | Q36687206 | ||
| Platelet-derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2 | Q36688353 | ||
| Overexpression of phospholipase C-gamma in NIH 3T3 fibroblasts results in increased phosphatidylinositol hydrolysis in response to platelet-derived growth factor and basic fibroblast growth factor | Q36733919 | ||
| Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells | Q36769553 | ||
| Detergent solubility defines an alternative itinerary for a subpopulation of PDGF beta receptors | Q36807980 | ||
| Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells | Q36826672 | ||
| Inhibitory DNA ligands to platelet-derived growth factor B-chain | Q36832312 | ||
| Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma. | Q36841179 | ||
| Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins | Q24336394 | ||
| NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain | Q24532124 | ||
| pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions | Q24561464 | ||
| Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells | Q24564451 | ||
| Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras | Q24564495 | ||
| Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation | Q24609334 | ||
| cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor | Q24612837 | ||
| Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity | Q24645473 | ||
| Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation | Q24646756 | ||
| Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism | Q27733279 | ||
| Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site | Q27740067 | ||
| The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors | Q27860467 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| SH2 domains recognize specific phosphopeptide sequences | Q27860748 | ||
| The small GTP-binding protein rac regulates growth factor-induced membrane ruffling | Q27861063 | ||
| Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia | Q27861126 | ||
| Cloning and characterization of GRB14, a novel member of the GRB7 gene family | Q28115522 | ||
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
| Signaling through scaffold, anchoring, and adaptor proteins | Q28131792 | ||
| Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways | Q28186742 | ||
| STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction | Q28236871 | ||
| PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells | Q28236975 | ||
| Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras | Q28238120 | ||
| PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase | Q28244045 | ||
| Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase | Q28246466 | ||
| c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells | Q28252598 | ||
| Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins | Q28253825 | ||
| Inositol trisphosphate and calcium signalling | Q28262867 | ||
| Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain | Q28280523 | ||
| A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a heterodimeric receptor complex | Q28286805 | ||
| Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors | Q28287661 | ||
| Interaction of the Nck adapter protein with p21-activated kinase (PAK1) | Q28291014 | ||
| The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways | Q37054452 | ||
| The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets | Q37371237 | ||
| The beta-PDGF receptor induces neuronal differentiation of PC12 cells | Q37372664 | ||
| Identification of a putative Syp substrate, the PDGF beta receptor | Q38291369 | ||
| Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways | Q38354870 | ||
| PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine | Q38551733 | ||
| Fibroblast growth factor-2 potentiates vascular smooth muscle cell migration to platelet-derived growth factor: upregulation of alpha2beta1 integrin and disassembly of actin filaments | Q39444387 | ||
| A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. | Q40020748 | ||
| Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation | Q40022461 | ||
| Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes | Q40346714 | ||
| Src family protein tyrosine kinases and cellular signal transduction pathways | Q40444974 | ||
| Tyrosine kinase inhibition: an approach to drug development | Q40613606 | ||
| Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis | Q40645844 | ||
| How receptor tyrosine kinases activate Ras. | Q40778358 | ||
| Growth factors in glomerulonephritis | Q40876115 | ||
| On the crawling of animal cells | Q40907482 | ||
| The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases | Q41056278 | ||
| Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. | Q41063499 | ||
| Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways. | Q41072512 | ||
| Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity | Q41092747 | ||
| Selective inhibition of platelet-derived growth factor (PDGF) receptor autophosphorylation and PDGF-mediated cellular events by a quinoline derivative. | Q41097409 | ||
| Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-zeta and Raf-1. | Q41099506 | ||
| Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1. | Q41115502 | ||
| Platelet-derived growth factor-dependent cellular transformation requires either phospholipase Cgamma or phosphatidylinositol 3 kinase | Q41116788 | ||
| Platelet-derived growth factor (PDGF)-induced Ca2+ signaling in the CG4 oligodendroglial cell line and in transformed oligodendrocytes expressing the beta-PDGF receptor | Q41127812 | ||
| Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. | Q41128352 | ||
| Platelet-derived growth factor is an autocrine stimulator for the growth and survival of human esophageal carcinoma cell lines | Q41155116 | ||
| Ligand-induced dimerization of growth factor receptors: variations on the theme | Q41157741 | ||
| Formation of STAT5-containing DNA binding complexes in response to colony-stimulating factor-1 and platelet-derived growth factor | Q41176633 | ||
| Identification of a domain within the carboxyl-terminal region of the beta platelet-derived growth factor (PDGF) receptor that mediates the high transforming activity of PDGF. | Q41199335 | ||
| Localization and down-regulating role of the protein tyrosine phosphatase PTP2C in membrane ruffles of PDGF-stimulated cells | Q41216651 | ||
| Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1. | Q41217316 | ||
| Structural determinants in the platelet-derived growth factor alpha-receptor implicated in modulation of chemotaxis. | Q41224734 | ||
| The phosphotyrosine phosphatase PTP1D, but not PTP1C, is an essential mediator of fibroblast proliferation induced by tyrosine kinase and G protein-coupled receptors | Q41347048 | ||
| PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase | Q41355420 | ||
| Involvement of loop 2 of platelet-derived growth factor-AA and -BB in receptor binding | Q41385508 | ||
| Platelet-derived growth factor-BB stimulates synthesis of the integrin alpha 2-subunit in human diploid fibroblasts | Q41426771 | ||
| Inhibition of G1 cyclin expression and G1 cyclin-dependent protein kinases by cAMP in an astrocytic cell line | Q41427256 | ||
| Tyrosine 508 of the 85-kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor | Q41442570 | ||
| Platelet-derived growth factor isoforms prevent cell death during starvation of AKR-2B fibroblasts | Q41450721 | ||
| The differential activation of phosphatidylinositol-3 kinase and mitogen-activated protein kinases by PDGF-AA and IGF-I might explain the synergistic effect of the two growth factors on the proliferation of AKR-2B fibroblasts | Q41457216 | ||
| Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling | Q41471394 | ||
| Regulation of chemotaxis by the platelet-derived growth factor receptor-beta | Q41488423 | ||
| Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line | Q41491473 | ||
| Inhibition by cAMP of Ras-Dependent Activation of Raf | Q41514458 | ||
| PDGF alpha- and beta-receptors activate unique and common signal transduction pathways | Q41516226 | ||
| Pool of ligand‐bound platelet‐derived growth factor β‐receptors remain activated and tyrosine phosphorylated after internalization | Q41540271 | ||
| Reversion of autocrine transformation by a dominant negative platelet-derived growth factor mutant | Q41545083 | ||
| Phospholipase C-gamma1: regulation of enzyme function and role in growth factor-dependent signal transduction | Q41551925 | ||
| A novel monoclonal antibody dependent on domain 5 of the platelet-derived growth factor beta receptor inhibits ligand binding and receptor activation | Q41583994 | ||
| Characterization of baculovirus-expressed human alpha and beta platelet-derived growth factor receptors | Q41594552 | ||
| Integrins and anoikis | Q41612562 | ||
| Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D. | Q41661194 | ||
| On the structure of platelet-derived growth factor AA: C-terminal processing, epitopes, and characterization of cysteine residues | Q41688183 | ||
| Ligand-induced interaction between alpha- and beta-type platelet-derived growth factor (PDGF) receptors: role of receptor heterodimers in kinase activation | Q41695110 | ||
| Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor | Q41697776 | ||
| Dominant-negative mutants of a platelet-derived growth factor gene | Q41711288 | ||
| Association between the PDGF receptor and members of the src family of tyrosine kinases | Q41725198 | ||
| Beta 1 integrin-mediated collagen gel contraction is stimulated by PDGF. | Q41745333 | ||
| Platelet-derived growth factor BB for the treatment of chronic pressure ulcers | Q41873116 | ||
| D-3 phosphoinositide metabolism in cells treated with platelet-derived growth factor | Q41904079 | ||
| Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway | Q41931967 | ||
| Involvement of phosphatidylinositide 3'-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis | Q42442838 | ||
| Regulation of platelet-derived growth factor receptor expression by cell context overrides regulation by cytokines | Q42524439 | ||
| Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro | Q42616486 | ||
| Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor | Q42768846 | ||
| A new series of PDGF receptor tyrosine kinase inhibitors: 3-substituted quinoline derivatives | Q42795835 | ||
| Disulfide bonds in recombinant human platelet-derived growth factor BB dimer: characterization of intermolecular and intramolecular disulfide linkages | Q46915844 | ||
| Inhibition of PDGF β Receptor Signal Transduction by Coexpression of a Truncated Receptor | Q46972012 | ||
| Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture | Q48387075 | ||
| Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. | Q50335523 | ||
| Similar action of platelet-derived growth factor and epidermal growth factor in the prereplicative phase of human fibroblasts suggests a common intracellular pathway. | Q51221704 | ||
| Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. | Q52516078 | ||
| Production of platelet-derived growth factor receptor (PDGFR-beta) in E. coli. Mapping ligand binding domain. | Q54640341 | ||
| Differential Requirement of a Motif within the Carboxyl-terminal Domain of α-Platelet-derived Growth Factor (αPDGF) Receptor for PDGF Focus Forming Activity Chemotaxis, or Growth | Q56453304 | ||
| Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins | Q57006559 | ||
| INDUCTION OF B-TYPE RECEPTORS FOR PLATELET-DERIVED GROWTH FACTOR IN VASCULAR INFLAMMATION: POSSIBLE IMPLICATIONS FOR DEVELOPMENT OF VASCULAR PROLIFERATIVE LESIONS | Q57352240 | ||
| PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis | Q57415025 | ||
| PLC-γ activation is required for PDGF-βR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells | Q58449641 | ||
| Cyclic AMP Inhibits PDGF-stimulated Mitogen-activated Protein Kinase Activity in Rat Aortic Smooth Muscle Cells via Inactivation of c-Raf-1 Kinase and Induction of MAP Kinase Phosphatase-1 | Q58450349 | ||
| PDGF stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells | Q61763092 | ||
| Identification of individual amino acids in platelet‐derived growth factor that contribute to the specificity towards the β‐type receptor | Q67489564 | ||
| Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF | Q68252685 | ||
| A monoclonal antibody against PDGF B-chain inhibits PDGF-induced DNA synthesis in C3H fibroblasts and prevents binding of PDGF to its receptor | Q68477694 | ||
| Effect of phospholipase C-gamma overexpression on PDGF-induced second messengers and mitogenesis | Q68770632 | ||
| Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins | Q70300742 | ||
| Localization of platelet-derived growth factor and insulin-like growth factor I in the fibrotic lung | Q70785252 | ||
| PDGF receptor-to-nucleus signaling of p91 (STAT1 alpha) transcription factor in rat smooth muscle cells | Q70868772 | ||
| Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells | Q70870927 | ||
| Localization of platelet-derived growth factor-stimulated phosphorylation cascade to caveolae | Q71070312 | ||
| Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle | Q71118080 | ||
| The synergistic effect of PDGF-AA and IGF-1 on VSMC proliferation might be explained by the differential activation of their intracellular signaling pathways | Q71139360 | ||
| In vitro characterization of a novel series of platelet-derived growth factor receptor tyrosine kinase inhibitors | Q71210008 | ||
| Maximal PDGF-induced lung fibroblast chemotaxis requires PDGF receptor-alpha | Q71404697 | ||
| Platelet-derived growth factor-induced formation of tensin and phosphoinositide 3-kinase complexes | Q71514783 | ||
| Structural role of extracellular domain 1 of alpha-platelet-derived growth factor (PDGF) receptor for PDGF-AA and PDGF-BB binding | Q71585627 | ||
| The fumagillin analogue TNP-470 inhibits DNA synthesis of vascular smooth muscle cells stimulated by platelet-derived growth factor and insulin-like growth factor-I. Possible involvement of cyclin-dependent kinase 2 | Q71590992 | ||
| The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction | Q71666764 | ||
| Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains | Q71673010 | ||
| A novel physiological function for platelet-derived growth factor-BB in rat dermis | Q71674003 | ||
| Induction of beta 1 integrin synthesis by recombinant platelet-derived growth factor (PDGF-AB) correlates with an enhanced migratory response of human dermal fibroblasts to various extracellular matrix proteins | Q71708829 | ||
| Differential chemotactic responses mediated by platelet-derived growth factor alpha- and beta-receptors | Q71778917 | ||
| Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor | Q72121269 | ||
| 5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase | Q72137957 | ||
| Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors | Q72148792 | ||
| Aggregation of PDGF-beta receptors in human skin fibroblasts: characterization by image correlation spectroscopy (ICS) | Q72998853 | ||
| Requirement of phosphatidylinositol-3 kinase for activation of JNK/SAPKs by PDGF | Q73283979 | ||
| Substantial inhibition of neo-intimal response to balloon injury in the rat carotid artery using a combination of antibodies to platelet-derived growth factor-BB and basic fibroblast growth factor | Q73286951 | ||
| Immunoglobulin-like domain 4-mediated receptor-receptor interactions contribute to platelet-derived growth factor-induced receptor dimerization | Q73316445 | ||
| Phosphorylation of a 72-kDa protein in PDGF-stimulated cells which forms complex with c-Crk, c-Fyn and Eps15 | Q73456570 | ||
| Identification of a cyclic peptide inhibitor of platelet-derived growth factor-BB receptor-binding and mitogen-induced DNA synthesis in human fibroblasts | Q73674260 | ||
| Functional importance of platelet-derived growth factor (PDGF) receptor extracellular immunoglobulin-like domains. Identification of PDGF binding site and neutralizing monoclonal antibodies | Q73959962 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | F79–113 | |
| P577 | publication date | 1998-08-19 | |
| P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
| P1476 | title | Signal transduction via platelet-derived growth factor receptors | |
| P478 | volume | 1378 |
| Q34233778 | 3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury |
| Q46407757 | A Phenanthrene Derivative, 5,7-Dimethoxy-1,4-Phenanthrenequinone, Inhibits Cell Adhesion Molecule Expression and Migration in Vascular Endothelial and Smooth Muscle Cells |
| Q83139111 | A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes |
| Q30477658 | A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells |
| Q35799977 | A naturally occurring carotenoid, lutein, reduces PDGF and H₂O₂ signaling and compromised migration in cultured vascular smooth muscle cells |
| Q36587386 | A possible additional diagnostic tool for cutaneous melanoma |
| Q36961428 | A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex |
| Q37189482 | A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor |
| Q37662243 | Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression |
| Q41505257 | Activation of protein kinase C alpha is necessary for sorting the PDGF beta-receptor to Rab4a-dependent recycling |
| Q24806905 | Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development |
| Q36965337 | Adenoviral gene transfer of PDGF downregulates gas gene product PDGFalphaR and prolongs ERK and Akt/PKB activation |
| Q33838902 | An ethanolic extract of Angelica gigas improves atherosclerosis by inhibiting vascular smooth muscle cell proliferation |
| Q89250918 | Angiogenesis and Hepatic Fibrosis: Western and Chinese Medicine Therapies on the Road |
| Q37139109 | Angiogenesis-related pathways in the pathogenesis of ovarian cancer |
| Q35205410 | Anti-vascular therapies in ovarian cancer: moving beyond anti-VEGF approaches. |
| Q57463353 | Assembly of fibronectin fibrils selectively attenuates platelet-derived growth factor-induced intracellular calcium release in fibroblasts |
| Q40343201 | Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer. |
| Q50297836 | Autophosphorylation of PDGF alpha receptors |
| Q50297837 | Autophosphorylation of PDGF alpha/beta receptors |
| Q50297835 | Autophosphorylation of PDGF beta receptors |
| Q35747522 | Blockade of platelet-derived growth factor receptor-beta pathway induces apoptosis of vascular endothelial cells and disrupts glomerular capillary formation in neonatal mice |
| Q40891304 | Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins |
| Q36893296 | C-reactive protein and vein graft disease: evidence for a direct effect on smooth muscle cell phenotype via modulation of PDGF receptor-beta |
| Q33509293 | Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1. |
| Q30492863 | Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. |
| Q34148152 | Cell receptors and cell signalling |
| Q37351510 | Changes in Otx2 and parvalbumin immunoreactivity in the superior colliculus in the platelet-derived growth factor receptor-β knockout mice |
| Q73438456 | Characterization of DNA-hyaluronan matrix for sustained gene transfer |
| Q73270829 | Characterization of the chronic myelomonocytic leukemia associated TEL-PDGF beta R fusion protein |
| Q33273613 | Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function |
| Q45885233 | Chitosan-plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies |
| Q36807957 | Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B |
| Q30476232 | Cognitive and socio-emotional deficits in platelet-derived growth factor receptor-β gene knockout mice |
| Q34103617 | Connecting signaling and cell cycle progression in growth factor-stimulated cells |
| Q38886353 | Constitutive activation of oncogenic PDGFRα-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRα signalling characteristics. |
| Q50297853 | Crk binds to the active PDGF receptor |
| Q41786171 | Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway |
| Q47728974 | Cytocapsular tubes conduct cell translocation |
| Q41764961 | Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas |
| Q48458385 | D2-class dopamine receptor inhibition of NMDA currents in prefrontal cortical neurons is platelet-derived growth factor receptor-dependent |
| Q40710486 | Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor |
| Q89907669 | Dental Pulp Stem Cells: Advances to Applications |
| Q41205725 | Dermatofibrosarcoma Protuberans-Like Tumor With COL1A1 Copy Number Gain in the Absence of t(17;22). |
| Q30476972 | Deterministic model of dermal wound invasion incorporating receptor-mediated signal transduction and spatial gradient sensing |
| Q37593021 | Differential tumorigenic potential and matriptase activation between PDGF B versus PDGF D in prostate cancer |
| Q30157067 | Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals |
| Q40379214 | Divergent roles of c-Src in controlling platelet-derived growth factor-dependent signaling in fibroblasts |
| Q45318075 | Downstream signal transduction |
| Q37635839 | Dual Inhibition of PI3K/AKT and MEK/ERK Pathways Induces Synergistic Antitumor Effects in Diffuse Intrinsic Pontine Glioma Cells |
| Q33968953 | E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion |
| Q41896516 | ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis |
| Q46223032 | Effect of PDGF-BB combined with EDTA gel on adhesion and proliferation to the root surface |
| Q36982758 | Effect of rhPDGF-BB delivery on mediators of periodontal wound repair |
| Q47362892 | Effect of shear stress on the migration of hepatic stellate cells |
| Q40565977 | Effect of sustained gene delivery of platelet-derived growth factor or its antagonist (PDGF-1308) on tissue-engineered cementum. |
| Q34853086 | Effects of imatinib mesylate on pulmonary allergic vasculitis in a murine model |
| Q41881088 | Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors |
| Q35601475 | Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension |
| Q35800580 | Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. |
| Q33686201 | FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains |
| Q33939204 | Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581 |
| Q35104697 | Fermented soshiho-tang with Lactobacillus plantarum enhances the antiproliferative activity in vascular smooth muscle cell. |
| Q36502974 | Fusion of platelet-derived growth factor receptor β to CEV14 gene in chronic myelomonocytic leukemia: A case report and review of the literature |
| Q50297849 | GAP binds to PDGF-beta receptors only |
| Q50297850 | GRB2:SOS1 complex binds to the active receptor |
| Q35843266 | Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans |
| Q33934157 | Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology |
| Q89162894 | Germline genetic variants were interactively associated with somatic alterations in gastric cancer |
| Q50297857 | Grb7 binds to the active PDGF receptor |
| Q64865970 | Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress |
| Q33814336 | Growth factor signaling pathways in vascular development |
| Q35128740 | Helium-neon laser irradiation promotes the proliferation and migration of human epidermal stem cells in vitro: proposed mechanism for enhanced wound re-epithelialization |
| Q24311672 | High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation |
| Q35531909 | History of discovery: platelet-derived growth factor |
| Q58706980 | Human chorionic villous mesenchymal stem/stromal cells protect endothelial cells from injury induced by high level of glucose |
| Q35412507 | Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β. |
| Q38949908 | Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling |
| Q33273344 | Imatinib in the treatment of solid tumours |
| Q36289382 | Immunohistochemical expression of platelet-derived growth factor receptors in ovarian cancer patients with long-term follow-up. |
| Q37924342 | Implication of platelet-derived growth factor receptor alpha in prostate cancer skeletal metastasis |
| Q30313218 | Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts |
| Q33651783 | In vitro effects of imatinib mesylate on radiosensitivity and chemosensitivity of breast cancer cells |
| Q40956511 | Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding |
| Q28581058 | Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells |
| Q37184064 | Initiation of oligodendrocyte progenitor cell migration by a PDGF-A activated extracellular regulated kinase (ERK) signaling pathway |
| Q42811942 | Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation |
| Q40852306 | Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells |
| Q43118428 | Intrathecal delivery of PDGF produces tactile allodynia through its receptors in spinal microglia |
| Q36303320 | Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading |
| Q47446419 | LOC285629 regulates cell proliferation and motility in colorectal cancer cells |
| Q43628844 | Ligand stimulation reduces platelet-derived growth factor beta-receptor susceptibility to tyrosine dephosphorylation |
| Q43003304 | Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF. |
| Q38722135 | Lipoxins inhibit Akt/PKB activation and cell cycle progression in human mesangial cells |
| Q39085121 | Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor |
| Q43125682 | Lycopene binding compromised PDGF-AA/-AB signaling and migration in smooth muscle cells and fibroblasts: prediction of the possible lycopene binding site within PDGF. |
| Q42423477 | Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells |
| Q35916552 | MUC1 regulates PDGFA expression during pancreatic cancer progression |
| Q36178668 | Malignant transformation but not normal cell growth depends on signal transducer and activator of transcription 3. |
| Q34727916 | Mesenchymal stem cell migration is regulated by fibronectin through α5β1-integrin-mediated activation of PDGFR-β and potentiation of growth factor signals |
| Q37714151 | MicroRNA-182 prevents vascular smooth muscle cell dedifferentiation via FGF9/PDGFRβ signaling |
| Q37027027 | Monitoring tumor response to linifanib therapy with SPECT/CT using the integrin αvβ3-targeted radiotracer 99mTc-3P-RGD2. |
| Q38620874 | Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK. |
| Q36006925 | Murrayafoline A Induces a G0/G1-Phase Arrest in Platelet-Derived Growth Factor-Stimulated Vascular Smooth Muscle Cells |
| Q30479197 | NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility |
| Q54966902 | Naked physically synthesized gold nanoparticles affect migration, mitochondrial activity, and proliferation of vascular smooth muscle cells. |
| Q33322533 | Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo |
| Q50297856 | Nck binds to the active PDGF receptor |
| Q58617548 | Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies |
| Q36936327 | Network inference using informative priors |
| Q37238690 | Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas |
| Q34166170 | Over-expression of PDGFR-β promotes PDGF-induced proliferation, migration, and angiogenesis of EPCs through PI3K/Akt signaling pathway |
| Q41197010 | Oxidative stress, prefrontal cortex hypomyelination and cognitive symptoms in schizophrenia |
| Q50297834 | PDGF dimer binds two receptors simultaneously |
| Q37775451 | PDGF function in diverse neural crest cell populations |
| Q35017837 | PDGF induced microRNA alterations in cancer cells |
| Q34577073 | PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation |
| Q24316140 | PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA |
| Q47911791 | PDGF receptor-β uses Akt/mTORC1 signaling node to promote high glucose-induced renal proximal tubular cell collagen I (α2) expression |
| Q38615308 | PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway |
| Q35680187 | PDGF-induced proliferation in human arterial and venous smooth muscle cells: molecular basis for differential effects of PDGF isoforms. |
| Q37718362 | PDGFR-alpha inhibits melanoma growth via CXCL10/IP-10: a multi-omics approach |
| Q42819833 | PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib |
| Q28085644 | PDGFRα in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer |
| Q36177630 | PDGFRβ(+)/c-kit(+) pulp cells are odontoblastic progenitors capable of producing dentin-like structure in vitro and in vivo |
| Q39166181 | PDGFs and their receptors |
| Q50297839 | PI3-kinase binds to the active receptor |
| Q37727180 | PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes |
| Q50297841 | PLC-gamma binds to the active receptor |
| Q37329008 | Pathway analysis of bladder cancer genome-wide association study identifies novel pathways involved in bladder cancer development |
| Q34116946 | Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling |
| Q29048615 | Pharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disorders |
| Q53076647 | Phase II study of olaratumab with paclitaxel/carboplatin (P/C) or P/C alone in previously untreated advanced NSCLC. |
| Q36390602 | Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling |
| Q42685797 | Platelet-derived growth factor (PDGF) isoform and PDGF receptor expression in drug-induced gingival overgrowth and hereditary gingival fibrosis. |
| Q41175151 | Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts |
| Q41183542 | Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes |
| Q35649971 | Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling |
| Q33390267 | Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway |
| Q43239881 | Platelet-derived growth factor gene delivery stimulates ex vivo gingival repair |
| Q33579520 | Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway |
| Q36528159 | Platelet-derived growth factor receptor alpha in glioma: a bad seed |
| Q24515074 | Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity |
| Q42114294 | Platelet-derived growth factor receptor beta signaling is required for efficient epicardial cell migration and development of two distinct coronary vascular smooth muscle cell populations |
| Q42161348 | Platelet-derived growth factor selectively inhibits NR2B-containing N-methyl-D-aspartate receptors in CA1 hippocampal neurons |
| Q51767513 | Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal. |
| Q44948904 | Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins |
| Q43243039 | Platelet-derived growth factor-B gene delivery sustains gingival fibroblast signal transduction |
| Q37608572 | Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt and Bad phosphorylation |
| Q42995228 | Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src. |
| Q41870700 | Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D |
| Q39817809 | Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo |
| Q42126072 | Platelet-derived growth factors and their receptors in normal and malignant hematopoiesis |
| Q42668157 | Platelet-derived growth factors induced lymphangiogenesis: evidence, unanswered questions and upcoming challenges. |
| Q38435882 | Positively and negatively modulating cell adhesion to type I collagen via peptide grafting. |
| Q39484324 | Potentiation of platelet-derived growth factor receptor-β signaling mediated by integrin-associated MFG-E8. |
| Q28208686 | Profiling of genes expressed in human monocytes and monocyte-derived dendritic cells using cDNA expression array |
| Q33949818 | Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding |
| Q42466117 | Proliferative capacity of venous ulcer wound fibroblasts in the presence of platelet-derived growth factor |
| Q42979847 | Protein kinase Cδ mediates MCP-1 mRNA stabilization in vascular smooth muscle cells |
| Q35185696 | Proteomics in studies of signal transduction in epithelial cells |
| Q36971305 | Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma. |
| Q41073793 | Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration |
| Q26801806 | Radiolabeled Cyclic RGD Peptide Bioconjugates as Radiotracers Targeting Multiple Integrins |
| Q60930283 | Randomized phase II study of the PDGFRα antibody olaratumab plus liposomal doxorubicin versus liposomal doxorubicin alone in patients with platinum-refractory or platinum-resistant advanced ovarian cancer |
| Q35012761 | Rare incidence of congestive heart failure in gastrointestinal stromal tumor and other sarcoma patients receiving imatinib mesylate |
| Q35006469 | Reactive oxygen species are required for 5-HT-induced transactivation of neuronal platelet-derived growth factor and TrkB receptors, but not for ERK1/2 activation |
| Q39528062 | Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation |
| Q40621014 | Receptor synergy of interleukin-6 (IL-6) and insulin-like growth factor-I in myeloma cells that highly express IL-6 receptor α |
| Q37884393 | Receptor tyrosine kinases in kidney development |
| Q37372330 | Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study |
| Q36328433 | Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin |
| Q34048479 | Reversal of experimental pulmonary hypertension by PDGF inhibition |
| Q34819874 | RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac. |
| Q35261176 | RhoB regulates PDGFR-beta trafficking and signaling in vascular smooth muscle cells |
| Q36817642 | Role and regulation of PDGFRα signaling in liver development and regeneration |
| Q34687531 | Role of neurotrophins on postnatal neurogenesis in the thalamus: prenatal exposure to ethanol |
| Q29615222 | Role of platelet-derived growth factors in physiology and medicine |
| Q36366957 | Role of the PI3K regulatory subunit in the control of actin organization and cell migration |
| Q50297845 | SH2 domain of Src binds to the active receptor |
| Q28207588 | SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor |
| Q41917289 | SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans |
| Q50297848 | SHP2 binds to the active receptor |
| Q50297851 | SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) |
| Q50297852 | STAT binds to the active receptor |
| Q24551043 | SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling |
| Q34720232 | Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells |
| Q45318074 | Signaling by PDGF |
| Q33939607 | Signaling in leukemia: which messenger to kill? |
| Q28744297 | Simultaneous visualization of both signaling cascade activity and end-point gene expression in single cells |
| Q22254150 | Site-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1 |
| Q24308779 | Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase |
| Q43755245 | Small molecule: large hopes |
| Q22253382 | Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression |
| Q36231607 | Stat1-independent regulation of gene expression in response to IFN-gamma |
| Q36392642 | Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts |
| Q40796943 | Structural and functional analysis of a chimeric protein COL1A1-PDGFB generated by the translocation t(17;22)(q22;q13.1) in Dermatofibrosarcoma protuberans (DP). |
| Q26829546 | Structural and functional properties of platelet-derived growth factor and stem cell factor receptors |
| Q34029444 | Sunitinib mesylate inhibits proliferation of human colonic stromal fibroblasts in vitro and in vivo |
| Q33589274 | TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB. |
| Q36539868 | Targeting protein-protein interactions by rational design: mimicry of protein surfaces |
| Q34393461 | Targeting the PDGF signaling pathway in tumor treatment |
| Q35569799 | Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. |
| Q37764646 | Tensegrin in context: Dual role of α8 integrin in the migration of different cell types |
| Q39647893 | The FGF-2-derived peptide FREG inhibits melanoma growth in vitro and in vivo |
| Q33874232 | The alpha-receptor for platelet-derived growth factor confers bone-metastatic potential to prostate cancer cells by ligand- and dimerization-independent mechanisms |
| Q39818667 | The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation |
| Q36173910 | The phosphorylation of myosin II at the Ser1 and Ser2 is critical for normal platelet-derived growth factor induced reorganization of myosin filaments |
| Q26852944 | The roles of PDGF in development and during neurogenesis in the normal and diseased nervous system |
| Q21203112 | The roles of platelet-derived growth factors and their receptors in brain radiation necrosis |
| Q42067514 | The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors |
| Q39016533 | The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V. |
| Q33696791 | Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma |
| Q50904199 | Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure. |
| Q39675890 | Transactivation of PDGFRbeta by dopamine D4 receptor does not require PDGFRbeta dimerization |
| Q34233512 | Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12. |
| Q34011759 | Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA |
| Q40549695 | Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-beta: evidence for different roles of Cys-822 and Cys-940 in the kinase activity |
| Q47757479 | Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy |
| Q42917525 | Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies |
| Q36409204 | VEGF-targeted therapy in renal cell carcinoma: active drugs and active choices |
| Q40468905 | c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. |
| Q50297855 | p130Cas and C3G bind PDGFR bound Crk |
| Q34326514 | β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice |
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