| scholarly article | Q13442814 |
| P50 | author | Richard Marais | Q30118915 |
| P2093 | author name string | Paterson HF | |
| Marshall CJ | |||
| Light Y | |||
| P2860 | cites work | Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1 | Q24309607 |
| Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src | Q24310206 | ||
| Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation | Q24319934 | ||
| Activation of Raf-1 by 14-3-3 proteins | Q24324360 | ||
| Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function | Q24324452 | ||
| Interaction of the protein kinase Raf-1 with 14-3-3 proteins | Q24329122 | ||
| Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP) | Q24336881 | ||
| Activation of ternary complex factor Elk-1 by MAP kinases | Q24564310 | ||
| Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1 | Q24596134 | ||
| Drosophila melanogaster homologs of the raf oncogene | Q24628183 | ||
| Mammalian Ras interacts directly with the serine/threonine kinase Raf | Q27860833 | ||
| Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product | Q27860841 | ||
| Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies | Q28116152 | ||
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
| Activation of the MAP kinase pathway by the protein kinase raf | Q28212495 | ||
| Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes | Q28247946 | ||
| Proteins regulating Ras and its relatives | Q28257295 | ||
| pEF-BOS, a powerful mammalian expression vector | Q29547606 | ||
| Catalytic specificity of protein-tyrosine kinases is critical for selective signalling | Q29616451 | ||
| Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane | Q29618478 | ||
| Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells | Q29618480 | ||
| Activation of Raf as a result of recruitment to the plasma membrane | Q29618481 | ||
| The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain | Q29620270 | ||
| Signalling through SH2 and SH3 domains | Q30195158 | ||
| Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase) | Q30446229 | ||
| Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase | Q30450248 | ||
| A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function | Q30454014 | ||
| Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase | Q30454103 | ||
| Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro | Q33292215 | ||
| Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity | Q33676544 | ||
| The Role of Raf-1 Phosphorylation in Signal Transduction | Q35225870 | ||
| Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase | Q36826443 | ||
| Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog | Q36903643 | ||
| Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family | Q36922463 | ||
| Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line | Q38915507 | ||
| Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues. | Q40791100 | ||
| The post-translational modification of ras p21 is important for Raf-1 activation. | Q41449123 | ||
| Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells. | Q41514986 | ||
| MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase | Q41539247 | ||
| Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter | Q41612990 | ||
| Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor | Q42796135 | ||
| Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain | Q42808327 | ||
| C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation. | Q48120347 | ||
| 3 Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to immobilon | Q67703557 | ||
| Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase | Q72186416 | ||
| The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex | Q72272832 | ||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 3136-3145 | |
| P577 | publication date | 1995-07-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation | |
| P478 | volume | 14 |
| Q37358674 | 1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells |
| Q39695510 | 14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity |
| Q33774875 | 14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo |
| Q35562896 | A mechanism for the evolution of phosphorylation sites |
| Q44877299 | A novel assay for the measurement of Raf-1 kinase activity |
| Q37325629 | A novel noncanonical signaling pathway for the μ-opioid receptor |
| Q91970742 | A rationally enhanced red fluorescent protein expands the utility of FRET biosensors |
| Q37387072 | A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation |
| Q48289134 | Abnormalities of protein kinases in neurodegenerative diseases. |
| Q38743591 | Activation kinetics of RAF protein in the ternary complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis |
| Q24562843 | Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase |
| Q59095906 | Activation of Raf by ionizing radiation |
| Q40792069 | Activation of Raf-1 is defective in annexin 6 overexpressing Chinese hamster ovary cells |
| Q40820045 | Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF. |
| Q40928369 | Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras. |
| Q24563004 | Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation |
| Q33883079 | Activation of protein kinase cascades in the heart by hypertrophic G protein-coupled receptor agonists |
| Q34394101 | Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization. |
| Q24533702 | Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells |
| Q39574246 | Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes. |
| Q39922817 | Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src |
| Q39102460 | Allosteric activation of functionally asymmetric RAF kinase dimers |
| Q36973814 | Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
| Q34259118 | Antagonistic effect of flavonoids on NSC-741909-mediated antitumor activity via scavenging of reactive oxygen species |
| Q36070859 | Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors |
| Q24684153 | Autoregulation of the Raf-1 serine/threonine kinase |
| Q38155724 | B-Raf mutation: a key player in molecular biology of cancer. |
| Q97525759 | BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy |
| Q40411337 | BRAF mutation detection and identification by cycling temperature capillary electrophoresis |
| Q30452664 | Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway |
| Q40925352 | Binding of Gbetagamma subunits to cRaf1 downregulates G-protein-coupled receptor signalling |
| Q24324674 | Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein |
| Q36563863 | Binding of human immunodeficiency virus type 1 to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway |
| Q51431702 | Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. |
| Q33965534 | Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors |
| Q41878303 | C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons |
| Q30164174 | C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin A expression and alterations of anchorage-independent growth. |
| Q41825679 | CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation |
| Q54734056 | CREB and AP-1 activation regulates MKP-1 induction by LPS or M-CSF and their kinetics correlate with macrophage activation versus proliferation. |
| Q34614474 | Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates |
| Q28646420 | Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation |
| Q37505664 | Cell and molecular biology of the novel protein tyrosine-phosphatase-interacting protein 51. |
| Q44109577 | Cellular information dynamics through transmembrane flow of ions |
| Q37477854 | Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase |
| Q39942488 | Characterization of Ser338 phosphorylation for Raf-1 activation |
| Q35184329 | Chronic myelogenous leukemia: a review and update of therapeutic strategies |
| Q22010710 | Cloning and characterization of a novel human phosphatidylinositol transfer protein, rdgBbeta |
| Q38193659 | Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy |
| Q39610851 | Complementation of defective colony-stimulating factor 1 receptor signaling and mitogenesis by Raf and v-Src |
| Q47094073 | Constitutively elevated levels of SOCS1 suppress innate responses in DF-1 immortalised chicken fibroblast cells |
| Q37109227 | Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. |
| Q33887809 | Control of B cell development by Ras-mediated activation of Raf. |
| Q35640301 | Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells |
| Q34333784 | Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway |
| Q37596593 | Coxsackievirus group B type 3 infection upregulates expression of monocyte chemoattractant protein 1 in cardiac myocytes, which leads to enhanced migration of mononuclear cells in viral myocarditis |
| Q39674723 | Cyclic AMP blocks cell growth through Raf-1-dependent and Raf-1-independent mechanisms |
| Q40105886 | Delineating v-Src downstream effector pathways in transformed myoblasts |
| Q28379145 | Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway |
| Q42159757 | Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-zeta |
| Q42683550 | Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization. |
| Q34093068 | Differentiation therapy of human cancer: basic science and clinical applications |
| Q33782337 | Disruption of the Shc/Grb2 complex during abelson virus transformation affects proliferation, but not apoptosis |
| Q47108778 | Dynamic modeling of folliculogenesis signaling pathways in the presence of miRNAs expression |
| Q36239135 | Dynamics of Ras complexes observed in living cells |
| Q81236740 | ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf |
| Q40827867 | Effect of protein kinase C inhibitor (PKCI) on radiation sensitivity and c-fos transcription |
| Q40877375 | Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells. |
| Q35028002 | Effects of mitogen-activated protein kinase kinase inhibitor PD 098059 on antigen challenge of guinea-pig airways in vitro |
| Q44419395 | Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells. |
| Q37676070 | Epidermal Growth Factor Pathway Signaling in Drosophila Embryogenesis: Tools for Understanding Cancer. |
| Q36401150 | Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant |
| Q33783051 | Expression of the pRb-binding regions of E1A enables efficient transformation of primary epithelial cells by v-src |
| Q28568168 | Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth |
| Q33745304 | Extracellular-signal-regulated kinase signalling in neurons |
| Q35801918 | Flotillin-1/reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling. |
| Q41785401 | Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation |
| Q38317592 | Functional Rac-1 and Nck signaling networks are required for FGF-2-induced DNA synthesis in MCF-7 cells |
| Q37218244 | Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines |
| Q28361532 | Geldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperones |
| Q34593862 | Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response. |
| Q34593871 | Genetic screen of a mutant poxvirus library identifies an ankyrin repeat protein involved in blocking induction of avian type I interferon |
| Q36563659 | Genetics of melanoma |
| Q33889310 | Glial cells as targets and producers of neurotrophins |
| Q33874057 | Growth factor-independent proliferation of erythroid cells infected with Friend spleen focus-forming virus is protein kinase C dependent but does not require Ras-GTP. |
| Q28214429 | Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway |
| Q93217157 | Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway |
| Q28648013 | Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding |
| Q28589914 | Identification of novel co-repressor molecules for Interferon Regulatory Factor-2 |
| Q63865751 | Identification of radiation-specific responses from gene expression profile |
| Q24294250 | Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling |
| Q34512913 | Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. |
| Q40022357 | Inhibition of the Raf-1 kinase by cyclic AMP agonists causes apoptosis of v-abl-transformed cells |
| Q48021735 | Insulin signal transduction through protein kinase cascades |
| Q22010135 | Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals |
| Q24646299 | Interaction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cells |
| Q28579361 | Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein |
| Q41080800 | Interactions between Ras proteins and their effectors |
| Q42476157 | Interactions of c-Raf-1 with phosphatidylserine and 14-3-3. |
| Q34279738 | Intracellular electric field and pH optimize protein localization and movement. |
| Q41102442 | Intracellular signalling: putting JAKs on the kinase MAP. |
| Q39078976 | KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma |
| Q39269556 | KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer |
| Q36819377 | KSR and CNK: two scaffolds regulating RAS-mediated RAF activation |
| Q22009020 | KSR-1 binds to G-protein betagamma subunits and inhibits beta gamma-induced mitogen-activated protein kinase activation |
| Q41110632 | Kinase connections on the cellular intranet. Signalling pathways. |
| Q43514105 | Kinase suppressor of Ras signals through Thr269 of c-Raf-1. |
| Q24298749 | Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF |
| Q34312909 | Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras |
| Q34721341 | LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA |
| Q30159670 | Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development |
| Q47612418 | Local substrates of non-receptor tyrosine kinases at synaptic sites in neurons |
| Q34274616 | Localization of phospholipase D1 to caveolin-enriched membrane via palmitoylation: implications for epidermal growth factor signaling. |
| Q28362229 | MEK kinase activity is not necessary for Raf-1 function |
| Q24532640 | MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42 |
| Q35058694 | Management of chronic myeloid leukemia: targets for molecular therapy |
| Q38197024 | Mechanism and consequences of RAF kinase activation by small-molecule inhibitors |
| Q39914626 | Mechanism of mda-5 Inhibition by paramyxovirus V proteins. |
| Q28183716 | Mechanisms of regulating the Raf kinase family |
| Q37785803 | Mechanistic principles of RAF kinase signaling |
| Q33941102 | Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. |
| Q47548527 | MiRNA Signaling in Viral Myocarditis Novel and Unique Pathological Features |
| Q38086019 | Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount. |
| Q28484612 | Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression |
| Q53418952 | Modulation of Gq-Rho Signaling by the ERK MAPK Pathway Controls Locomotion in Caenorhabditis elegans. |
| Q35001415 | Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab |
| Q27025381 | Molecular therapies in hepatocellular carcinoma: what can we target? |
| Q52553630 | Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo. |
| Q40019933 | Negative regulation of Raf-1 by phosphorylation of serine 621. |
| Q39584779 | Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca(2+) and calmodulin. |
| Q42528881 | Neurotransmitter- and growth factor-induced cAMP response element binding protein phosphorylation in glial cell progenitors: role of calcium ions, protein kinase C, and mitogen-activated protein kinase/ribosomal S6 kinase pathway. |
| Q41661619 | Neurotrophin regulation of gene expression. |
| Q39482480 | New modalities in oncology: antisense oligonucleotides. |
| Q24299821 | Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia |
| Q24317206 | Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans |
| Q43772601 | Nonisotopic methods for detecting activation of small G proteins |
| Q33869015 | Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element |
| Q28609906 | Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2 |
| Q41527398 | Oncoprotein Signalling and Mitosis |
| Q33853144 | Oxidative stress and gene regulation |
| Q40790669 | P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells. |
| Q28188974 | PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation |
| Q40738816 | PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. |
| Q64993325 | PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas. |
| Q30452661 | Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation |
| Q50292932 | Phosphorylation of RAF |
| Q24645562 | Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling |
| Q42512195 | Phosphorylation of the C-Raf N-region promotes Raf dimerization |
| Q40803062 | Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src. |
| Q33783041 | Plasma membrane-targeted Raf kinase activates NF-kappaB and human immunodeficiency virus type 1 replication in T lymphocytes |
| Q41099506 | Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-zeta and Raf-1. |
| Q24596504 | Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis |
| Q34080535 | Positive and negative regulation of Raf kinase activity and function by phosphorylation |
| Q36367050 | Positive and negative selection invoke distinct signaling pathways. |
| Q34303405 | Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis |
| Q24319548 | Protein binding and signaling properties of RIN1 suggest a unique effector function |
| Q46723181 | Protein kinase C activity is necessary for estrogen-induced Erk phosphorylation in neocortical explants |
| Q28211695 | Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions |
| Q40939214 | Protein-protein interactions. Putting the pieces together |
| Q71011188 | Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo |
| Q42813519 | R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras |
| Q37662202 | RALB provides critical survival signals downstream of Ras in acute myeloid leukemia |
| Q34202692 | RAS Interaction with PI3K: More Than Just Another Effector Pathway |
| Q58763445 | RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation |
| Q27333187 | Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila |
| Q24316181 | Raf family kinases: old dogs have learned new tricks |
| Q60084134 | Raf gets it together |
| Q36002845 | Raf kinases: function, regulation and role in human cancer |
| Q42820755 | Raf-1 Is Activated during Mitosis |
| Q24522903 | Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation |
| Q39528226 | Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt. |
| Q41434222 | Ras and its effectors |
| Q41099716 | Ras effectors |
| Q37548931 | Ras signaling and therapies |
| Q38739118 | Ras triggers acidosis-induced activation of the extracellular-signal-regulated kinase pathway in cardiac myocytes |
| Q49874520 | Ras-Mediated Activation of the Raf Family Kinases |
| Q30452710 | Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation |
| Q24554485 | Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf |
| Q41659032 | Regulation and function of the JNK subgroup of MAP kinases |
| Q39980994 | Regulation of BRAF protein stability by a negative feedback loop involving the MEK-ERK pathway but not the FBXW7 tumour suppressor. |
| Q38439535 | Regulation of RAF protein kinases in ERK signalling |
| Q28344727 | Regulation of Raf-1 activation and signalling by dephosphorylation |
| Q42034188 | Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling |
| Q24323233 | Regulation of growth and survival of activated T cells by cell-transducing inhibitors of Ras |
| Q41647860 | Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors |
| Q39426606 | Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association. |
| Q40020874 | Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase |
| Q28288349 | Role of the BLT2, a leukotriene B4 receptor, in Ras transformation |
| Q34966603 | Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging |
| Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
| Q24550986 | S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3 |
| Q35210205 | Senescence of human fibroblasts induced by oncogenic Raf. |
| Q24534094 | Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation |
| Q35166852 | Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. |
| Q36795284 | Signal transduction pathways that contribute to myeloid differentiation |
| Q41750250 | Signal transduction through MAP kinase cascades |
| Q28609164 | Signal transduction via platelet-derived growth factor receptors |
| Q41135422 | Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling |
| Q51839948 | Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells. |
| Q37319491 | Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling |
| Q42813355 | Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit |
| Q34087763 | Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2. |
| Q42506759 | Spatial regulation of ARAF controls the MST2-Hippo pathway. |
| Q64892583 | Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs. |
| Q34583708 | Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation. |
| Q41667115 | Steroid-independent activation of androgen receptor in androgen-independent prostate cancer: a possible role for the MAP kinase signal transduction pathway? |
| Q28769590 | Stimulation of gene induction and cell growth by the Ras effector Rlf |
| Q37213038 | Stimulatory role of PKCalpha in extracellular regulated kinase 1/2 pathway in conjunctival goblet cell proliferation |
| Q41049587 | Studies of perinuclear and nuclear translocation of the Raf-1 protein in rodent fibroblasts |
| Q35018805 | Synergistic effects of concurrent blockade of PI3K and MEK pathways in pancreatic cancer preclinical models |
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| Q90533622 | Tamoxifen-Induced Apoptosis of MCF-7 Cells via GPR30/PI3K/MAPKs Interactions: Verification by ODE Modeling and RNA Sequencing |
| Q35822194 | Targeted agents for the treatment of metastatic melanoma |
| Q27002288 | Targeted therapy for hepatocellular carcinoma: novel agents on the horizon |
| Q92663940 | Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy |
| Q28201363 | Targeting RAS signalling pathways in cancer therapy |
| Q48166242 | Targeting Ras signaling in AML: RALB is a small GTPase with big potential. |
| Q34659415 | Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators |
| Q33823577 | Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells. |
| Q40154931 | Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance. |
| Q38482694 | The African swine fever virus DP71L protein recruits the protein phosphatase 1 catalytic subunit to dephosphorylate eIF2alpha and inhibits CHOP induction but is dispensable for these activities during virus infection |
| Q24811271 | The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles |
| Q35203423 | The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis |
| Q24532906 | The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3 |
| Q27477650 | The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation |
| Q24646620 | The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization |
| Q29620153 | The RAF proteins take centre stage |
| Q34241295 | The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors |
| Q36780542 | The Ras/Raf/MAPK pathway |
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