| scholarly article | Q13442814 |
| P50 | author | James A. McCubrey | Q42317570 |
| William Blalock | Q57233815 | ||
| Richard A. Franklin | Q68547480 | ||
| Linda S Steelman | Q114723345 | ||
| P2093 | author name string | Martin McMahon | |
| John T Lee | |||
| John G Shelton | |||
| Amer M Mirza | |||
| Phillip W Moye | |||
| Steven L Knapp | |||
| Steven C Pohnert | |||
| P2860 | cites work | Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation | Q24312168 |
| Phosphorylation and regulation of Raf by Akt (protein kinase B) | Q28138863 | ||
| Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras | Q28238120 | ||
| Oncogene activation: c-raf-1 gene mutations in experimental and naturally occurring tumors | Q28267177 | ||
| Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase | Q28283499 | ||
| Regulation of Raf-1 activation and signalling by dephosphorylation | Q28344727 | ||
| Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs | Q28609063 | ||
| Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation | Q28609129 | ||
| Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line | Q29547239 | ||
| Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase | Q30450248 | ||
| Serine/threonine phosphorylation in cytokine signal transduction | Q33818655 | ||
| The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors | Q34241295 | ||
| PKB/AKT: functional insights from genetic models | Q34389540 | ||
| Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf | Q34515800 | ||
| Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation | Q36490362 | ||
| Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation | Q36561047 | ||
| Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways | Q36564768 | ||
| Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. | Q36572588 | ||
| Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation | Q36716270 | ||
| Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors | Q37554117 | ||
| Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells. | Q38311147 | ||
| Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells. | Q38311150 | ||
| Phosphoinositide 3-kinases: a conserved family of signal transducers | Q38556727 | ||
| Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals | Q39458674 | ||
| Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. | Q39674554 | ||
| Negative regulation of Raf-1 by phosphorylation of serine 621. | Q40019933 | ||
| P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells. | Q40790669 | ||
| Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf. | Q40802206 | ||
| Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells | Q40804306 | ||
| Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155. | Q40876072 | ||
| Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells. | Q40877375 | ||
| Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism | Q40887173 | ||
| A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells. | Q40896676 | ||
| Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. | Q40915594 | ||
| p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway | Q40915839 | ||
| A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf | Q40969113 | ||
| Interactions between Ras and Raf: key regulatory proteins in cellular transformation | Q40974378 | ||
| Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells | Q40989764 | ||
| Phosphatidylinositol 3' kinase: one of the effectors of Ras. | Q40998287 | ||
| Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1. | Q41092757 | ||
| Steroid receptor fusion proteins for conditional activation of Raf-MEK-ERK signaling pathway | Q42829924 | ||
| Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor kappaB-mediated antiapoptosis involving c-IAP2. | Q43757339 | ||
| Downstream signalling events regulated by phosphatidylinositol 3-kinase activity | Q48002873 | ||
| Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL). | Q48329182 | ||
| Cooperating oncogenes converge to regulate cyclin/cdk complexes. | Q53445613 | ||
| The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells | Q57272881 | ||
| Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells | Q57754173 | ||
| Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338 | Q61640742 | ||
| Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1 | Q73006592 | ||
| Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells | Q73166100 | ||
| Involvement of B-Raf in Ras-induced Raf-1 activation | Q77129692 | ||
| Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase | Q77195536 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2478-2492 | |
| P577 | publication date | 2003-04-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells | |
| P478 | volume | 22 |
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