| scholarly article | Q13442814 |
| review article | Q7318358 |
| P6179 | Dimensions Publication ID | 1018176267 |
| P356 | DOI | 10.1038/SJ.LEU.2401657 |
| P698 | PubMed publication ID | 10637471 |
| P5875 | ResearchGate publication ID | 12677939 |
| P2093 | author name string | McCubrey JA | |
| May WS | |||
| Duronio V | |||
| Mufson A | |||
| P2860 | cites work | Apoptosis meets signal transduction: elimination of a BAD influence | Q71802220 |
| Ras-dependent growth factor regulation of MEK kinase in PC12 cells | Q72156822 | ||
| Effect of dietary fat on colonic protein kinase C and induction of aberrant crypt foci | Q72559599 | ||
| Tyrosine phosphorylation of DNA binding proteins by multiple cytokines | Q72936922 | ||
| The role of serine/threonine phosphorylation in hematopoietic cytokine receptor signal transduction | Q73075405 | ||
| A phosphatidylcholine phospholipase C inhibitor, D609, blocks interleukin-3 (IL-3)-induced bcl-2 expression but not c-myc expression in human IL-3-dependent cells | Q74577860 | ||
| Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling | Q77206625 | ||
| Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells | Q77984628 | ||
| Function of WW domains as phosphoserine- or phosphothreonine-binding modules | Q22008803 | ||
| Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis | Q24311518 | ||
| Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2 | Q24313872 | ||
| Endothelial apoptosis in Braf-deficient mice | Q24314857 | ||
| Bcl-2 targets the protein kinase Raf-1 to mitochondria | Q24321753 | ||
| The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase | Q24567715 | ||
| The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins | Q24606249 | ||
| Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase | Q24682825 | ||
| Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality | Q24685515 | ||
| Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent | Q27739821 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins | Q27860890 | ||
| Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 | Q28114883 | ||
| A human peptidyl-prolyl isomerase essential for regulation of mitosis | Q28117639 | ||
| Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase | Q28145921 | ||
| A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells | Q28237789 | ||
| Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt | Q28255373 | ||
| Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity | Q28263808 | ||
| Jak2 is essential for signaling through a variety of cytokine receptors | Q28270987 | ||
| Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase | Q28280649 | ||
| Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A | Q28291327 | ||
| Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK) | Q28292617 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase | Q28581201 | ||
| Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses | Q28592023 | ||
| Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase | Q28609041 | ||
| Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs | Q28609063 | ||
| Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells | Q28609131 | ||
| Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense | Q28609612 | ||
| Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133 | Q28611436 | ||
| Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism | Q29614787 | ||
| Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease | Q29615967 | ||
| Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain | Q29620169 | ||
| Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK | Q29620274 | ||
| Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes | Q30193438 | ||
| Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase | Q30450248 | ||
| Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway | Q30452664 | ||
| Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein | Q31940050 | ||
| Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase | Q33774328 | ||
| Interleukin 2 signaling involves the phosphorylation of Stat proteins | Q34007160 | ||
| Inactivation of Bcl-2 by phosphorylation | Q34340301 | ||
| The modular phosphorylation and activation of p70s6k. | Q34434557 | ||
| Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses | Q34468309 | ||
| Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction | Q35319681 | ||
| Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis | Q36256627 | ||
| Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl | Q36365946 | ||
| Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes | Q36377021 | ||
| T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells | Q36400646 | ||
| Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis | Q36451137 | ||
| Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation | Q36490362 | ||
| Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways | Q36564768 | ||
| Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. | Q36572588 | ||
| Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter | Q36665347 | ||
| B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues. | Q37376649 | ||
| Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes. | Q38345701 | ||
| Phosphoinositide 3-kinases: a conserved family of signal transducers | Q38556727 | ||
| Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor | Q39551502 | ||
| Induction of early response genes by interferons, interleukins, and growth factors by the tyrosine phosphorylation of latent transcription factors. Implications for chronic inflammatory diseases | Q40402460 | ||
| Signal transduction pathways involving the Raf proto-oncogene | Q40733258 | ||
| Regulation of the Jak/STAT signalling pathway | Q40964979 | ||
| A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf | Q40969113 | ||
| Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells | Q40989764 | ||
| Phosphatidylinositol 3' kinase: one of the effectors of Ras. | Q40998287 | ||
| A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis | Q41008797 | ||
| Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor | Q41024206 | ||
| Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation | Q41044152 | ||
| Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent | Q41063440 | ||
| Bcl-2 phosphorylation required for anti-apoptosis function | Q41111068 | ||
| Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes | Q41150387 | ||
| Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines | Q41182918 | ||
| Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway | Q41190428 | ||
| Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin | Q41197202 | ||
| Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death | Q41228964 | ||
| Granulocyte-macrophage colony-stimulating factor induces the transcriptional activation of egr-1 through a protein kinase A-independent signaling pathway | Q41258176 | ||
| Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein | Q41326706 | ||
| Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation | Q41431083 | ||
| Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase | Q41608842 | ||
| TOR signalling and control of cell growth | Q41678494 | ||
| Mechanisms and consequences of activation of protein kinase B/Akt | Q41751003 | ||
| Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells. | Q41812650 | ||
| Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating | Q41992885 | ||
| Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases | Q42801780 | ||
| Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts | Q42817515 | ||
| Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling | Q43762918 | ||
| Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene. | Q45971337 | ||
| Downstream signalling events regulated by phosphatidylinositol 3-kinase activity | Q48002873 | ||
| Craf-1 protein kinase is essential for mouse development. | Q51990813 | ||
| Rho family proteins and Ras transformation: the RHOad less traveled gets congested. | Q53429986 | ||
| Differential effects of retroviral long terminal repeats on interleukin-3 gene expression and autocrine transformation. | Q53440045 | ||
| Cooperating oncogenes converge to regulate cyclin/cdk complexes. | Q53445613 | ||
| Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells. | Q54118063 | ||
| Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. | Q55066450 | ||
| Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells | Q57754173 | ||
| Two Discrete Regions of Interleukin-2 (IL2) Receptor β Independently Mediate IL2 Activation of a PD98059/Rapamycin/Wortmannin-insensitive Stat5a/b Serine Kinase | Q61277457 | ||
| Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells | Q71149530 | ||
| Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins | Q71768175 | ||
| P433 | issue | 1 | |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 9-21 | |
| P577 | publication date | 2000-01-01 | |
| P1433 | published in | Leukemia | Q6534498 |
| P1476 | title | Serine/threonine phosphorylation in cytokine signal transduction | |
| P478 | volume | 14 |
| Q41748150 | A PI3K pathway mediates hair cell survival and opposes gentamicin toxicity in neonatal rat organ of Corti. |
| Q43692571 | A novel differentiation-inducing therapy for acute promyelocytic leukemia with a combination of arsenic trioxide and GM-CSF. |
| Q37691482 | A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor |
| Q38282728 | A positive feedback loop between prolactin and STAT5 promotes angiogenesis |
| Q43767578 | Activation of Raf/ERK1/2 MAP kinase pathway is involved in GM-CSF-induced proliferation and survival but not in erythropoietin-induced differentiation of TF-1 cells |
| Q40014726 | Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in RAW 264.7 macrophages |
| Q45015877 | Aldosterone activates the oncogenic signals ERK1/2 and STAT3 via redox-regulated mechanisms |
| Q36973814 | Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
| Q30453010 | Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes |
| Q40663206 | Calcium induces cell survival and proliferation through the activation of the MAPK pathway in a human hormone-dependent leukemia cell line, TF-1. |
| Q34527660 | Cellular signalling pathways: new targets in leukaemia therapy |
| Q34323738 | Ceramide regulates cellular homeostasis via diverse stress signaling pathways |
| Q53761571 | Characterization of promoter elements directing Mona/Gads molecular adapter expression in T and myelomonocytic cells: involvement of the AML-1 transcription factor. |
| Q44182246 | Characterization of the promoter controlling Mona/Gads expression in the megakaryocytic lineage |
| Q35079054 | Clinical applications of cytokine assays. |
| Q56896764 | Combination therapies in advanced melanoma |
| Q37109227 | Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. |
| Q40635020 | Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation |
| Q40525959 | Dual function of interleukin-1beta for the regulation of interleukin-6-induced suppressor of cytokine signaling 3 expression |
| Q28570594 | Effects of HMGB1 on PMN apoptosis during LPS-induced acute lung injury |
| Q40516595 | Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells |
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| Q33893378 | Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells |
| Q44658021 | Expression of galectin‐3 in neuronally differentiating PC12 cells is regulated both via Ras/MAPK‐dependent and –independent signalling pathways |
| Q40751532 | Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line |
| Q40489436 | G-CSF induces stabilization of ETS protein Fli-1 during myeloid cell development |
| Q24795458 | Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals |
| Q42168728 | Hematopoietic stem cells and other hematopoietic cells show broad resistance to chemotherapeutic agents in vivo when overexpressing bcl-2. |
| Q40634397 | Increases in c-Jun N-terminal kinase/stress-activated protein kinase and p38 activity in monocyte-derived macrophages following the uptake of Legionella pneumophila |
| Q34043823 | Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer |
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