| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1010826794 |
| P356 | DOI | 10.1038/SJ.LEU.2403052 |
| P698 | PubMed publication ID | 12970777 |
| P5875 | ResearchGate publication ID | 10570171 |
| P2093 | author name string | Lee JT | |
| Franklin RA | |||
| Blalock WL | |||
| McCubrey JA | |||
| McMahon M | |||
| Steelman LS | |||
| Shelton JG | |||
| Moye PW | |||
| P2860 | cites work | Mutations of the BRAF gene in human cancer | Q27860760 |
| Phosphorylation and regulation of Raf by Akt (protein kinase B) | Q28138863 | ||
| A synthetic inhibitor of the mitogen-activated protein kinase cascade | Q28367955 | ||
| Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs | Q28609063 | ||
| Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells | Q28609131 | ||
| Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases | Q28609156 | ||
| Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase | Q30450248 | ||
| BAY 43-9006: early clinical data in patients with advanced solid malignancies | Q30736946 | ||
| The development and therapeutic potential of protein kinase inhibitors | Q33695725 | ||
| Serine/threonine phosphorylation in cytokine signal transduction | Q33818655 | ||
| The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy | Q34093787 | ||
| Kinases: positive and negative regulators of apoptosis. | Q34144498 | ||
| Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. | Q34184917 | ||
| The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors | Q34241295 | ||
| Suppression of apoptosis: role in cell growth and neoplasia | Q34309816 | ||
| Mechanisms of resistance to imatinib (STI571) and prospects for combination with conventional chemotherapeutic agents | Q34341014 | ||
| Discovery of a novel Raf kinase inhibitor | Q34376383 | ||
| Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf | Q34515800 | ||
| The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia | Q34605237 | ||
| MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products | Q34756212 | ||
| Antisense anticancer oligonucleotide therapeutics | Q34790443 | ||
| Design and discovery of small molecules targeting raf-1 kinase | Q34946014 | ||
| Targeting the Raf kinase cascade in cancer therapy--novel molecular targets and therapeutic strategies | Q35020561 | ||
| Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. | Q35166852 | ||
| Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation | Q35688302 | ||
| Growth of factor-dependent hemopoietic precursor cell lines | Q36344083 | ||
| Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells | Q36555259 | ||
| Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells. | Q38311147 | ||
| Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells. | Q38311150 | ||
| B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway | Q39446559 | ||
| Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals | Q39458674 | ||
| Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling | Q39665762 | ||
| Anti-(Raf-1) RNA aptamers that inhibit Ras-induced Raf-1 activation. | Q40749465 | ||
| Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line | Q40751532 | ||
| P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells. | Q40790669 | ||
| Oncogene-dependent engraftment of human myeloid leukemia cells in immunosuppressed mice | Q40804297 | ||
| Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells | Q40804306 | ||
| Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism | Q40887173 | ||
| A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells. | Q40896676 | ||
| Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. | Q40915594 | ||
| Paradoxical activation of Raf by a novel Raf inhibitor | Q40939473 | ||
| Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells | Q40989764 | ||
| Ras- and Raf-induced down-modulation of non-muscle tropomyosin are MEK-independent | Q40993730 | ||
| Characterization of proteins binding the 3' regulatory region of the IL-3 gene in IL-3-dependent and autocrine-transformed hematopoietic cells. | Q41049079 | ||
| Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1. | Q41092757 | ||
| Jaks and Stats in cytokine signaling | Q41642054 | ||
| Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor kappaB-mediated antiapoptosis involving c-IAP2. | Q43757339 | ||
| Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia. | Q44452162 | ||
| Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase | Q46110468 | ||
| A Raf-induced, MEK-independent signaling pathway regulates atrial natriuretic factor gene expression in cardiac muscle cells | Q47595039 | ||
| Differential effects of retroviral long terminal repeats on interleukin-3 gene expression and autocrine transformation. | Q53440045 | ||
| Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells | Q57369846 | ||
| Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells | Q73166100 | ||
| Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias | Q73674673 | ||
| Effect of SB 203580 on the activity of c-Raf in vitro and in vivo | Q77733964 | ||
| P433 | issue | 9 | |
| P304 | page(s) | 1765-1782 | |
| P577 | publication date | 2003-09-01 | |
| P1433 | published in | Leukemia | Q6534498 |
| P1476 | title | Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation | |
| P478 | volume | 17 |
| Q36973814 | Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
| Q36139849 | Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways |
| Q36597945 | Cell biology of membrane trafficking in human disease |
| Q37012150 | Deguelin Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells through Regulating the Expression of Galectin-1. |
| Q58806326 | Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer |
| Q37588717 | Emerging Raf inhibitors. |
| Q30420962 | Evaluating Inhibition of the Epidermal Growth Factor (EGF)-Induced Response of Mutant MCF10A Cells with an Acoustic Sensor |
| Q40501536 | Inhibition of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in B-lineage ALL in the presence of stromal cell support. |
| Q35635353 | JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis |
| Q38590189 | MAP kinases and the inflammatory signaling cascade as targets for the treatment of endometriosis? |
| Q36736547 | MR-1 blocks the megakaryocytic differentiation and transition of CML from chronic phase to blast crisis through MEK dephosphorylation |
| Q35145197 | Multiple model-informed open-loop control of uncertain intracellular signaling dynamics |
| Q47688064 | New perspectives for targeting RAF kinase in human cancer. |
| Q38090673 | New therapeutic approaches to acute myeloid leukemia |
| Q47755290 | RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells |
| Q35911472 | Raf and VEGF: emerging therapeutic targets in Kaposi's sarcoma-associated herpesvirus infection and angiogenesis in hematopoietic and nonhematopoietic tumors |
| Q40560220 | Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection. |
| Q24645668 | Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance |
| Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
| Q35217401 | Small-molecule inhibitors of signal transduction pathways in leukemia therapeutics: how to assess selectivity for malignant signals |
| Q37109225 | Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. |
| Q36804407 | Targeting the PI3K and MAPK pathways to treat Kaposi's-sarcoma-associated herpes virus infection and pathogenesis |
| Q36052399 | The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and |
| Q52727884 | The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis. |
| Q36268324 | The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what's genetics got to do with it? |
| Q36156821 | The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation. |
| Q37837732 | Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways. |
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