| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0092-8674(00)81231-3 |
| P698 | PubMed publication ID | 8646773 |
| P50 | author | R. B. Zipursky | Q24067148 |
| Paul A Garrity | Q42364838 | ||
| Iris Salecker | Q59158047 | ||
| P2093 | author name string | J McGlade | |
| T Pawson | |||
| Y Rao | |||
| P2860 | cites work | Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor | Q24311075 |
| The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors | Q24600645 | ||
| Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3 | Q24616611 | ||
| Binding of NCK to SOS and activation of ras-dependent gene expression | Q24652890 | ||
| Basic local alignment search tool | Q25938991 | ||
| Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions | Q27729407 | ||
| Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck | Q27729903 | ||
| Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms | Q27729904 | ||
| Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia | Q27861126 | ||
| brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2 | Q28181639 | ||
| Identification of a mouse p21Cdc42/Rac activated kinase | Q28289355 | ||
| Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map | Q28295221 | ||
| Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation | Q28576655 | ||
| Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase | Q28646514 | ||
| Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav | Q29615971 | ||
| The GRB2/Sem-5 adaptor protein | Q30194559 | ||
| Proteins with SH2 and SH3 domains couple receptor tyrosine kinases to intracellular signalling pathways | Q30194974 | ||
| Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning | Q33845816 | ||
| In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases | Q34058301 | ||
| Transposition of cloned P elements into Drosophila germ line chromosomes. | Q34253758 | ||
| Cell polarization directed by extracellular cues in yeast | Q34445847 | ||
| Monoclonal antibodies against the Drosophila nervous system | Q36328006 | ||
| Regulated tyrosine phosphorylation at the tips of growth cone filopodia | Q36383181 | ||
| Embryonic development of the antennal lobes of a hemimetabolous insect, the cockroach Periplaneta americana: light and electron microscopic observations | Q36678076 | ||
| Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal-regulated kinase | Q37103397 | ||
| Axon guidance molecules | Q40430552 | ||
| Making the connection: Cytoskeletal rearrangements during growth cone guidance | Q40430559 | ||
| Neuronal target recognition. | Q40430565 | ||
| Synaptic structure and function: Dynamic organization yields architectural precision | Q40430569 | ||
| GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more | Q40508472 | ||
| Developmental mechanisms that generate precise patterns of neuronal connectivity | Q40873406 | ||
| Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled | Q41870117 | ||
| FGF signaling and target recognition in the developing Xenopus visual system | Q43416917 | ||
| Induction in the developing compound eye of Drosophila: multiple mechanisms restrict R7 induction to a single retinal precursor cell | Q44825791 | ||
| Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster | Q45300018 | ||
| Mutations disrupting neuronal connectivity in the Drosophila visual system. | Q45999264 | ||
| The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation | Q46045354 | ||
| The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system | Q46456013 | ||
| Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member | Q46529688 | ||
| Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion | Q46580381 | ||
| Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo | Q46600134 | ||
| The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila | Q47071521 | ||
| Fate mapping of nervous system and other internal tissues in genetic mosaics of Drosophila melanogaster. | Q52432349 | ||
| The influence of retinal innervation on neurogenesis in the first optic ganglion of Drosophila. | Q52447044 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Drosophila | Q312154 |
| photoreceptor protein | Q7187894 | ||
| SH3 domain | Q24771787 | ||
| P304 | page(s) | 639-650 | |
| P577 | publication date | 1996-05-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein | |
| P478 | volume | 85 |
| Q47987718 | A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase |
| Q34589821 | A Drosophila model of multiple endocrine neoplasia type 2. |
| Q30176885 | A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance |
| Q30176651 | A casein kinase I activity is constitutively associated with Nck. |
| Q35945717 | A gain-of-function screen for genes that influence axon guidance identifies the NF-kappaB protein dorsal and reveals a requirement for the kinase Pelle in Drosophila photoreceptor axon targeting |
| Q24321546 | A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs |
| Q46360346 | A polarity field is established early in the development of the Drosophila compound eye. |
| Q47070315 | A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis. |
| Q58756442 | A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye |
| Q24684919 | A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function |
| Q31022299 | Aberrant protein expression in cerebral cortex of fetus with Down syndrome |
| Q30168785 | Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development |
| Q30009885 | Activated Cdc42 kinase regulates Dock localization in male germ cells during Drosophila spermatogenesis |
| Q30176648 | Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. |
| Q24542519 | Alternative splicing of the Drosophila Dscam pre-mRNA is both temporally and spatially regulated |
| Q36896424 | An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance. |
| Q30175420 | Angiotensin II stimulates serine phosphorylation of the adaptor protein Nck: physical association with the serine/threonine kinases Pak1 and casein kinase I |
| Q36069368 | Axon guidance at the midline: from mutants to mechanisms |
| Q35574548 | Axon guidance mechanisms and molecules: lessons from invertebrates. |
| Q34560919 | Axon guidance: the cytoplasmic tail |
| Q35069002 | Axon targeting in the Drosophila visual system. |
| Q46798482 | Bifocal and PP1 interaction regulates targeting of the R-cell growth cone in Drosophila |
| Q30165032 | Bifocal is a downstream target of the Ste20-like serine/threonine kinase misshapen in regulating photoreceptor growth cone targeting in Drosophila |
| Q37801481 | Building a fly eye: terminal differentiation events of the retina, corneal lens, and pigmented epithelia |
| Q28269278 | Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta |
| Q24532077 | Compartmentalization of visual centers in the Drosophila brain requires Slit and Robo proteins |
| Q33745357 | Conservation and divergence of axon guidance mechanisms. |
| Q30009072 | Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck. |
| Q45007574 | Coordinating structural and functional synapse development: postsynaptic p21-activated kinase independently specifies glutamate receptor abundance and postsynaptic morphology. |
| Q47071989 | Differential accumulation of DPTP61F alternative transcripts: regulation of a protein tyrosine phosphatase by segmentation genes |
| Q89129240 | Direct Phosphorylation of SRC Homology 3 Domains by Tyrosine Kinase Receptors Disassembles Ligand-Induced Signaling Networks |
| Q24810133 | Dissecting Nck/Dock signaling pathways in Drosophila visual system |
| Q30159490 | Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy |
| Q30010287 | Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling |
| Q24535902 | Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak. |
| Q30176256 | Domain requirements for the Dock adapter protein in growth- cone signaling |
| Q24296950 | Downstream of guidance receptors: entering the baroque period of axon guidance signaling |
| Q30167698 | Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance |
| Q29622856 | Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity |
| Q35772931 | Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer's Disease |
| Q46188477 | Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells |
| Q41265373 | Enlightening the path of axons |
| Q33292526 | Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells |
| Q28139507 | Eph receptors and ephrins: regulators of guidance and assembly |
| Q36653366 | EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak. |
| Q30176566 | Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development |
| Q34974027 | Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development |
| Q31965148 | Glial cells mediate target layer selection of retinal axons in the developing visual system of Drosophila. |
| Q42824083 | Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK). |
| Q43762442 | Guidance of cell migration by the Drosophila PDGF/VEGF receptor |
| Q43819365 | Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons |
| Q38912876 | Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in axon guidance in Drosophila. |
| Q35055168 | Homeotic Gene teashirt (tsh) has a neuroprotective function in amyloid-beta 42 mediated neurodegeneration |
| Q31965095 | Identification and characterization of kraken, a gene encoding a putative hydrolytic enzyme in Drosophila melanogaster |
| Q28203896 | Identification and kinetic analysis of the interaction between Nck-2 and DOCK180 |
| Q22008787 | Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck |
| Q24313473 | Identification of Nck family genes, chromosomal localization, expression, and signaling specificity |
| Q27219697 | Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC |
| Q30009489 | Independent signaling by Drosophila insulin receptor for axon guidance and growth |
| Q44012234 | Integrins regulate responsiveness to slit repellent signals. |
| Q24554208 | Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation |
| Q28564174 | Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site |
| Q30498647 | Isolation of mutations in the Drosophila homologues of the human Neurofibromatosis 2 and yeast CDC42 genes using a simple and efficient reverse-genetic method. |
| Q24532273 | Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells |
| Q92214491 | Leptin signaling impairs macrophage defenses against Salmonella Typhimurium |
| Q53830407 | Linking neuronal lineage and wiring specificity. |
| Q34952879 | Making connections in the fly visual system |
| Q28569216 | Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate |
| Q24682810 | Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein |
| Q30175873 | Mechanism of activation of Pak1 kinase by membrane localization |
| Q28579492 | Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells |
| Q30175408 | Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins |
| Q41290845 | Molecular biology of axon guidance |
| Q24336334 | Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 |
| Q33599007 | Molecular mechanisms of neurite extension |
| Q46598406 | N-cadherin regulates target specificity in the Drosophila visual system |
| Q24532124 | NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain |
| Q30157533 | Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor |
| Q28754341 | Nck adaptor proteins control the organization of neuronal circuits important for walking |
| Q28187612 | Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway |
| Q24296809 | Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress |
| Q24320914 | Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase |
| Q28214529 | Nck-2 interacts with focal adhesion kinase and modulates cell motility |
| Q24655497 | Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways |
| Q24554304 | Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation |
| Q34361675 | Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells |
| Q30167854 | Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton |
| Q30009308 | Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression |
| Q90283008 | Nck2 is essential for limb trajectory selection by spinal motor axons |
| Q30157941 | Nckbeta adapter controls neuritogenesis by maintaining the cellular paxillin level |
| Q24551163 | Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb |
| Q36549477 | Nckβ Interacts with Tyrosine-Phosphorylated Disabled 1 and Redistributes in Reelin-Stimulated Neurons |
| Q47071825 | Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS. |
| Q30164261 | Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila |
| Q33594307 | Neuronal guidance. A genetic perspective |
| Q35068917 | Neurons take shape |
| Q30157347 | Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration |
| Q39682563 | Novel p21-activated kinase-dependent protrusions characteristically formed at the edge of transformed cells |
| Q73881219 | Orchestral maneuvers in the axon: trio and the control of axon guidance |
| Q24318480 | PAK signalling in neuronal physiology |
| Q41005044 | PY in the fly receptor-like tyrosine phosphatases in axonal pathfinding |
| Q30175404 | Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila |
| Q89239766 | Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses |
| Q45296540 | Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. |
| Q47587007 | RPM-1 regulates axon termination by affecting growth cone collapse and microtubule stability. |
| Q28362128 | Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis |
| Q28647329 | Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76 |
| Q41650140 | Retinal axon target selection in Drosophila is regulated by a receptor protein tyrosine phosphatase |
| Q28647606 | Rho GTPases in growth cone guidance |
| Q29620432 | Rho GTPases in neuronal morphogenesis |
| Q41353297 | Rho family GTP-binding proteins in growth cone signalling |
| Q34232693 | Rhodopsin-regulated insulin receptor signaling pathway in rod photoreceptor neurons |
| Q24321934 | SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1 |
| Q28201752 | Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway |
| Q33680921 | Signal transduction underlying growth cone guidance by diffusible factors |
| Q28609164 | Signal transduction via platelet-derived growth factor receptors |
| Q47754321 | Signaling by Eph receptors and their ephrin ligands |
| Q35610287 | Signalling mechanisms mediating neuronal responses to guidance cues |
| Q30164473 | Slit Stimulation Recruits Dock and Pak to the Roundabout Receptor and Increases Rac Activity to Regulate Axon Repulsion at the CNS Midline |
| Q43744867 | Soluble guanylate cyclase is required during development for visual system function in Drosophila. |
| Q34819202 | Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase |
| Q33339394 | Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system |
| Q22010654 | TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton |
| Q30175380 | Targeted expression of an oncogenic adaptor protein v-Crk potentiates axonal growth in dorsal root ganglia and motor neurons in vivo |
| Q33845842 | The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. |
| Q30155605 | The C. elegans nck-1 gene encodes two isoforms and is required for neuronal guidance |
| Q30175160 | The Drosophila HEM-2/NAP1 homolog KETTE controls axonal pathfinding and cytoskeletal organization. |
| Q47863008 | The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension. |
| Q41651168 | The Eph family in the patterning of neural development |
| Q30165392 | The Nck family of adapter proteins: regulators of actin cytoskeleton |
| Q28216283 | The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals |
| Q30175289 | The SH2/SH3 adaptor protein dock interacts with the Ste20-like kinase misshapen in controlling growth cone motility |
| Q30168981 | The Ste20 kinase misshapen regulates both photoreceptor axon targeting and dorsal closure, acting downstream of distinct signals |
| Q28278822 | The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck |
| Q30165268 | The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism |
| Q40547533 | The adaptor protein Nck1 mediates endothelin A receptor-regulated cell migration through the Cdc42-dependent c-Jun N-terminal kinase pathway |
| Q39775960 | The conserved Ig superfamily member Turtle mediates axonal tiling in Drosophila. |
| Q30155611 | The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance |
| Q33957684 | The cytoskeleton in lymphocyte signaling |
| Q47071182 | The egghead gene is required for compartmentalization in Drosophila optic lobe development. |
| Q41353241 | The genetics of visual system development in Drosophila: specification, connectivity and asymmetry |
| Q43166012 | The guanine exchange factor vav controls axon growth and guidance during Drosophila development. |
| Q33951997 | The midline glia of Drosophila: a molecular genetic model for the developmental functions of glia. |
| Q24682994 | The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network |
| Q37629726 | The roles of the dystrophin-associated glycoprotein complex at the synapse |
| Q30167933 | The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton |
| Q36294306 | Thinking about visual behavior; learning about photoreceptor function |
| Q30479913 | Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach |
| Q36040816 | Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual Development |
| Q30168983 | Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila |
| Q42247979 | Turtle interacts with borderless in regulating glial extension and axon ensheathment |
| Q24534026 | Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migration |
| Q30169019 | Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. |
| Q34575844 | Visual circuit assembly in Drosophila |
| Q24599228 | Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells |
| Q35755944 | brakeless is required for photoreceptor growth-cone targeting in Drosophila |
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