| scholarly article | Q13442814 |
| P2093 | author name string | J M Lehmann | |
| J P Johnson | |||
| G Riethmüller | |||
| P2860 | cites work | Similarity in membrane proteins | Q59002438 |
| MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily | Q34325680 | ||
| Oncogenes and cell control | Q58985088 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | SH3 domain | Q24771787 |
| P304 | page(s) | 1048 | |
| P577 | publication date | 1990-02-25 | |
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3 | |
| P478 | volume | 18 |
| Q41409157 | A 66-kDa protein associated with epidermal growth factor receptor is a proteolytic fragment of phosphoinositide-specific phospholipase C. |
| Q30176885 | A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance |
| Q30039659 | A Novel Ligand for SH3 Domains |
| Q24321546 | A Novel Ligand for an SH3 Domain of the Adaptor Protein Nck Bears an SH2 Domain and Nuclear Signaling Motifs |
| Q30176651 | A casein kinase I activity is constitutively associated with Nck. |
| Q30194218 | A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment. |
| Q24318312 | A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner |
| Q30010244 | A uNick protein |
| Q30168785 | Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development |
| Q30192989 | Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity |
| Q30176648 | Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. |
| Q28215657 | Activation of Wiskott-Aldrich syndrome protein and its association with other proteins by stromal cell-derived factor-1alpha is associated with cell migration in a T-lymphocyte line |
| Q30175353 | Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck. |
| Q30175420 | Angiotensin II stimulates serine phosphorylation of the adaptor protein Nck: physical association with the serine/threonine kinases Pak1 and casein kinase I |
| Q43560430 | Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck. |
| Q22009484 | Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes |
| Q28264351 | Association of the Cas-like Molecule HEF1 with CrkL Following Integrin and Antigen Receptor Signaling in Human B-Cells: Potential Relevance to Neoplastic Lymphohematopoietic Cells |
| Q24652890 | Binding of NCK to SOS and activation of ras-dependent gene expression |
| Q30195542 | Biological and biochemical activity of v-Crk chimeras containing the SH2/SH3 regions of phosphatidylinositol-specific phospholipase C-gamma and Src |
| Q30194957 | Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells |
| Q29618334 | C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains |
| Q22009400 | Characterization of interactions of Nck with Sos and dynamin |
| Q28505581 | Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells |
| Q24563818 | Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries |
| Q60063697 | Conviction by genetics |
| Q30009858 | Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol |
| Q30193645 | Crk interacts with tyrosine-phosphorylated p116 upon T cell activation |
| Q28578126 | CrkII signals from epidermal growth factor receptor to Ras |
| Q43534834 | Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice |
| Q30417036 | Depletion of the adaptor protein NCK increases UV-induced p53 phosphorylation and promotes apoptosis |
| Q46528006 | Determination of Phosphorylation Sites in Peptides and Proteins Employing a Volatile Edman Reagent |
| Q42815996 | Differential effects of carboxy-terminal sequence deletions on platelet-derived growth factor receptor signaling activities and interactions with cellular substrates |
| Q28587659 | Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3 |
| Q30192897 | Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins |
| Q28277700 | Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase |
| Q24810133 | Dissecting Nck/Dock signaling pathways in Drosophila visual system |
| Q30176256 | Domain requirements for the Dock adapter protein in growth- cone signaling |
| Q30176960 | Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. |
| Q24564389 | Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals |
| Q39434675 | Essential role of the adaptor protein Nck1 in Jurkat T cell activation and function |
| Q30009017 | Expression of GADS enhances FLT3-induced mitogenic signaling. |
| Q30176566 | Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development |
| Q22010490 | Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk |
| Q24647075 | Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins |
| Q40018492 | Functional interactions of phosphatidylinositol 3-kinase with GTPase-activating protein in 3T3-L1 adipocytes. |
| Q28204312 | HSH2: A Novel SH2 Domain-Containing Adapter Protein Involved in Tyrosine Kinase Signaling in Hematopoietic Cells |
| Q24563877 | High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains |
| Q28203896 | Identification and kinetic analysis of the interaction between Nck-2 and DOCK180 |
| Q22008787 | Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck |
| Q24313473 | Identification of Nck Family Genes, Chromosomal Localization, Expression, and Signaling Specificity |
| Q30164096 | Identification of Nck interacting proteins in vascular smooth muscle cells |
| Q24651040 | Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G |
| Q24522731 | Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons |
| Q30195712 | Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins |
| Q30987442 | Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression |
| Q24314627 | In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase |
| Q24530109 | Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac |
| Q31169174 | Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors |
| Q28291014 | Interaction of the Nck adapter protein with p21-activated kinase (PAK1) |
| Q24337412 | Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes |
| Q28290100 | Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor |
| Q36325295 | Kinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance |
| Q30175931 | Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. |
| Q30175408 | Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins |
| Q22008626 | Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1 |
| Q24310780 | Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites |
| Q24320914 | Nck Recruitment to Eph Receptor, EphB1/ELK, Couples Ligand Activation to c-Jun Kinase |
| Q30157533 | Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor |
| Q30194642 | Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells |
| Q24296809 | Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress |
| Q24319666 | Nck-1 interacts with PKR and modulates its activation by dsRNA |
| Q28214529 | Nck-2 interacts with focal adhesion kinase and modulates cell motility |
| Q24655497 | Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways |
| Q24554304 | Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation |
| Q30167854 | Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton |
| Q42827332 | Nck1 deficiency accelerates unloading‐induced bone loss |
| Q31033276 | Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo |
| Q93511366 | New nucleotide sequence data on the EMBL File Server |
| Q30009442 | Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation |
| Q30194476 | Oncogenes, protein tyrosine kinases, and signal transduction |
| Q41964209 | Phosphatidylinositol 3-kinase binds to alpha-actinin through the p85 subunit |
| Q41845103 | Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization |
| Q24600695 | Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP |
| Q28144566 | R-Ras contains a proline-rich site that binds to SH3 domains and is required for integrin activation by R-Ras |
| Q28647329 | Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76 |
| Q30175422 | Requirement of multiple SH3 domains of Nck for ligand binding |
| Q36962473 | SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors |
| Q30195496 | SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma |
| Q30168343 | SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor protein that is developmentally regulated during cardiac myocyte differentiation |
| Q24311668 | Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B |
| Q37212669 | Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases |
| Q30194563 | Specificity of protein interactions with highly related SRC homology (SH) domains of FGR and FYN protein-tyrosine kinases |
| Q28574428 | Splicing isoforms of rat Ash/Grb2. Isolation and characterization of the cDNA and genomic DNA clones and implications for the physiological roles of the isoforms |
| Q27730215 | Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk |
| Q33178119 | Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins |
| Q30165392 | The Nck family of adapter proteins: regulators of actin cytoskeleton |
| Q24600645 | The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors |
| Q24337017 | The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling |
| Q30195199 | The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels |
| Q30175289 | The SH2/SH3 adaptor protein dock interacts with the Ste20-like kinase misshapen in controlling growth cone motility |
| Q24600605 | The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment |
| Q28304242 | The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R |
| Q28278822 | The Wiskott-Aldrich Syndrome Protein-interacting Protein (WIP) Binds to the Adaptor Protein Nck |
| Q24337241 | The human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5. |
| Q24682994 | The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network |
| Q41357971 | The neurotrophic action and signalling of epidermal growth factor |
| Q73909431 | The phosphopeptide-binding specificity of Src family SH2 domains |
| Q30159822 | The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains. |
| Q43149205 | The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling |
| Q40454708 | The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors. |
| Q40406078 | The role of phosphotyrosine signaling pathway in a parotid gland proliferation and function |
| Q37636620 | Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene |
| Q24311075 | Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor |
| Q28273862 | Two-dimensional electrophoretic analysis of mixed lineage kinase 2 N-terminal domain binding proteins |
| Q24651136 | Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains |
| Q24309118 | Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization |
| Q24595669 | c-Abl kinase regulates the protein binding activity of c-Crk |
Search more.