scholarly article | Q13442814 |
P50 | author | Philippe Soriano | Q55300601 |
Michelle D Tallquist | Q57176344 | ||
P2093 | author name string | Wendy J French | |
P2860 | cites work | Mechanism of action and in vivo role of platelet-derived growth factor | Q22010594 |
Binding of GAP to activated PDGF receptors | Q24302443 | ||
Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases | Q24309883 | ||
The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp | Q24310396 | ||
Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor | Q24310840 | ||
Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor | Q24311075 | ||
Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors | Q24322730 | ||
Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation | Q24609334 | ||
Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis | Q24681191 | ||
Direct interaction between Shc and the platelet-derived growth factor beta-receptor | Q28254337 | ||
Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal | Q28297924 | ||
Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor | Q28359936 | ||
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice | Q28504776 | ||
Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development | Q28508377 | ||
Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse | Q28512852 | ||
Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae | Q28570390 | ||
The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions | Q28585894 | ||
Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli | Q28588857 | ||
Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis | Q28595010 | ||
Signal transduction via platelet-derived growth factor receptors | Q28609164 | ||
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro | Q28625928 | ||
Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins | Q28645718 | ||
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice | Q29615196 | ||
Active and inactive protein kinases: structural basis for regulation | Q29616320 | ||
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase | Q29618387 | ||
An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. | Q52125462 | ||
Disruption of T cell signaling networks and development by Grb2 haploid insufficiency. | Q52137761 | ||
Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors. | Q52163714 | ||
Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. | Q52169994 | ||
Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages. | Q52189117 | ||
Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene. | Q52189742 | ||
Direct and long-range action of a DPP morphogen gradient. | Q52201537 | ||
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. | Q52529779 | ||
Drosophila hedgehog acts as a morphogen in cellular patterning. | Q52544707 | ||
Regulation and role of PDGF receptor alpha-subunit expression during embryogenesis | Q67854812 | ||
Src family tyrosine kinases and the response to platelet-derived growth factor | Q70478999 | ||
Widespread recombinase expression using FLPeR (flipper) mice | Q73266365 | ||
A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells | Q73367364 | ||
PDGFR alpha expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFR alpha antibody APA5 | Q73451233 | ||
Expression of platelet-derived growth factor and its receptors in the developing and adult mouse kidney | Q77291514 | ||
The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes | Q29619826 | ||
Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex | Q30450356 | ||
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility | Q30835829 | ||
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities | Q33491173 | ||
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. | Q33491174 | ||
Developmental biology of the vascular smooth muscle cell: building a multilayered vessel wall | Q33537227 | ||
Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF | Q33887469 | ||
Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase | Q33922224 | ||
Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy | Q34090428 | ||
Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF. | Q34114977 | ||
Developmental roles of platelet-derived growth factors | Q34269318 | ||
Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses | Q34668023 | ||
Evolutionary Divergence of Platelet-Derived Growth Factor Alpha Receptor Signaling Mechanisms | Q35002367 | ||
Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos | Q35206785 | ||
Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling | Q35649971 | ||
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors | Q36257661 | ||
Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation | Q36552522 | ||
Analysis of mutant platelet-derived growth factor receptors expressed in PC12 cells identifies signals governing sodium channel induction during neuronal differentiation | Q36564624 | ||
Identification of a putative Syp substrate, the PDGF beta receptor | Q38291369 | ||
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases. | Q40021748 | ||
Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways | Q40445775 | ||
Analysis of mural cell recruitment to tumor vessels | Q40759893 | ||
Signal transduction by the PDGF receptors | Q40760083 | ||
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes | Q40946341 | ||
Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding | Q40956511 | ||
Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis | Q41077471 | ||
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling | Q41471394 | ||
Regulation of chemotaxis by the platelet-derived growth factor receptor-beta | Q41488423 | ||
Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. | Q41489527 | ||
Association between the PDGF receptor and members of the src family of tyrosine kinases | Q41725198 | ||
PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex | Q41737568 | ||
Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye. | Q42636311 | ||
The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration. | Q42832939 | ||
Coupling Met to specific pathways results in distinct developmental outcomes | Q43656791 | ||
Combinatorial signaling in the specification of unique cell fates | Q46692883 | ||
Direct and long-range action of a wingless morphogen gradient | Q47071257 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Platelet derived growth factor receptor, beta polypeptide | Q21983261 |
P304 | page(s) | E52 | |
P577 | publication date | 2003-11-17 | |
P1433 | published in | PLOS Biology | Q1771695 |
P1476 | title | Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development | |
P478 | volume | 1 |
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