Philippe Soriano

Professor, Icahn School of Medicine at Mt. Sinai

Philippe Soriano is …
instance of (P31):
humanQ5

External links are
P2381Academic Tree ID655810
P1960Google Scholar author ID8yd3g_EAAAAJ
P496ORCID iD0000-0002-0427-926X
P3829Publons author ID2414986
P1053ResearcherIDE-5797-2015
P1153Scopus author ID7005335043

P166award receivedThe Pew Charitable TrustsQ201296
Howard Hughes Medical InstituteQ1512226
Edwin Grant Conklin MedalQ5346461
NIH MERIT awardQ28456505
P27country of citizenshipUnited States of AmericaQ30
FranceQ142
P69educated atUniversity of ParisQ209842
P108employerFred Hutchinson Cancer Research CenterQ1452369
Icahn School of Medicine at Mount SinaiQ1950740
Baylor College of MedicineQ2892284
P734family nameSorianoQ21448758
SorianoQ21448758
SorianoQ21448758
P101field of workdevelopmental biologyQ213713
P735given namePhilippeQ15727189
PhilippeQ15727189
P2650interested ingeneticsQ7162
developmental biologyQ213713
signal transductionQ828130
P1412languages spoken, written or signedFrenchQ150
P106occupationprofessorQ121594
biologistQ864503
researcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q38771228A Thousand and One Receptor Tyrosine Kinases: Wherein the Specificity?
Q35004587A critical role for PDGFRα signaling in medial nasal process development.
Q40802053A gene trap vector system for identifying transcriptionally responsive genes.
Q100414764A most formidable arsenal: genetic technologies for building a better mouse
Q28585038A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling
Q33491174Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.
Q71606712Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
Q24806905Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development
Q52127938An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus.
Q52125462An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development.
Q52111063Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells.
Q28584704Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
Q52189117Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages.
Q30450960Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen
Q52214725Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.
Q52028262Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development.
Q47684005Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation
Q47318698Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency
Q42228181Double minute amplification of mutant PDGF receptor α in a mouse glioma model
Q47744494Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification
Q41615790EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.
Q41492017Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.
Q34530611Engineering mutations: deconstructing the mouse gene by gene.
Q37951183Eph/ephrin signaling: genetic, phosphoproteomic, and transcriptomic approaches.
Q28296703Ephrin signaling in vivo: look both ways
Q34127484Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.
Q37247119Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism
Q52169994Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function.
Q35002367Evolutionary Divergence of Platelet-Derived Growth Factor Alpha Receptor Signaling Mechanisms
Q102053682FGF signaling regulates development by processes beyond canonical pathways
Q36070434Fgfr1 regulates development through the combinatorial use of signaling proteins.
Q61661485Gene Targeting in ES Cells
Q37779132Gene trap mutagenesis in the mouse.
Q27860837Generalized lacZ expression with the ROSA26 Cre reporter strain
Q33764904Generation of an immortalized mouse embryonic palatal mesenchyme cell line
Q44550463Genes Coding for Vimentin and Actin in Mammals and Birds
Q28066570Genetic insights into the mechanisms of Fgf signaling
Q40757543Genetics of signal transduction: tales from the mouse.
Q83835684Genotyping Embryonic Stem (ES) Cell Colonies Prior to Picking
Q59085509High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse
Q33269338High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells.
Q72093589Histomorphometric and immunocytochemical studies of src-related osteopetrosis
Q51021575Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis.
Q24338349Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
Q48153530Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.
Q28508517In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis
Q40785332In vivo expression of rat insulin after intravenous administration of the liposome-entrapped gene for rat insulin I.
Q34944999Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis
Q33257263Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome
Q88766405Intersectional gene inactivation: there is more to conditional mutagenesis than Cre
Q41075059Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.
Q48451285L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns.
Q52221306Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.
Q49905672MAPK and PI3K Signaling: at the Crossroads of Neural Crest Development.
Q28590972Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics
Q80072849Mouse development: from black eyes to knockouts
Q36234811NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice
Q36264747Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature
Q28251995Neuronal position in the developing brain is regulated by mouse disabled-1
Q36301037Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.
Q24537603Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.
Q28593571PDGF signaling specificity is mediated through multiple immediate early genes
Q57415022PDGFB Regulates the Development of the Labyrinthine Layer of the Mouse Fetal Placenta
Q28592140PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis
Q37461467PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα
Q34191687PDGFRβ signaling regulates mural cell plasticity and inhibits fat development.
Q28512064PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways
Q46525440Pharmacological and genetic approaches to the analysis of tyrosine kinase function in long-term potentiation
Q52480438Phosphorylation of c-Src on Tyrosine 527 by Another Protein Tyrosine Kinase
Q35649971Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling
Q29616222Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice
Q28083779Receptor tyrosine kinase signaling: regulating neural crest development one phosphate at a time
Q35669628Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways
Q35607627Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice
Q94586365Response
Q69811705Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death
Q43932335Retroviruses as probes for mammalian development: allocation of cells to the somatic and germ cell lineages.
Q42550359SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling.
Q33936487Sequence interpretation. Functional annotation of mouse genome sequences
Q36276643Sequence organization and genomic distribution of the major family of interspersed repeats of mouse DNA
Q36202584Sox10ER(T2) CreER(T2) mice enable tracing of distinct neural crest cell populations.
Q41324364Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.
Q30014832Src family kinases are required for integrin but not PDGFR signal transduction.
Q68091639Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes
Q33888207Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation.
Q29547898Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
Q84713021Technological advances in mouse development studies. Preface
Q25255719The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse
Q28587022The PDGF signaling pathway controls multiple steroid-producing lineages
Q37607373The distribution of interspersed repeats is nonuniform and conserved in the mouse and human genomes.
Q41296918The genes coding for the cytoskeletal proteins actin and vimentin in warm-blooded vertebrates
Q28504830The helix-loop-helix gene E2A is required for B cell formation
Q22122054The knockout mouse project
Q28280321The major components of the mouse and human genomes. 1. Preparation, basic properties and compositional heterogeneity
Q72894353The major components of the mouse and human genomes. 2. Reassociation kinetics
Q36599019The scattered distribution of actin genes in the mouse and human genomes
Q28585894The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions
Q42166747The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling
Q28240545Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice
Q73266365Widespread recombinase expression using FLPeR (flipper) mice
Q24652657[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier
Q63226061pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
Q42165937β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis

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