| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1030955834 |
| P356 | DOI | 10.1038/367474A0 |
| P698 | PubMed publication ID | 8107807 |
| P50 | author | Lewis T. Williams | Q111445253 |
| Jaime A. Escobedo | Q111458215 | ||
| Bruce R Zetter | Q116547864 | ||
| P2093 | author name string | A Kazlauskas | |
| H K Kim | |||
| S G Rhee | |||
| V Kundra | |||
| P2860 | cites work | The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes | Q24680160 |
| Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways | Q28186742 | ||
| Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors | Q28242471 | ||
| Role of phosphatidylinositol kinase in PDGF receptor signal transduction | Q28645684 | ||
| Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1 | Q28645716 | ||
| Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors | Q29616545 | ||
| Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex | Q30450356 | ||
| Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C | Q34314810 | ||
| Platelet-derived growth factor in chemotactic for fibroblasts | Q36205866 | ||
| Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively | Q36658598 | ||
| PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254. | Q41684625 | ||
| PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex | Q41737568 | ||
| A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF. | Q43419428 | ||
| A novel class of unstable 6-thioguanine-resistant cells from dog and human kidneys | Q54382528 | ||
| Diacylglycerol-stimulated formation of actin nucleation sites at plasma membranes | Q54382866 | ||
| P433 | issue | 6462 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chemotaxis | Q658145 |
| P304 | page(s) | 474-476 | |
| P577 | publication date | 1994-02-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Regulation of chemotaxis by the platelet-derived growth factor receptor-beta | |
| P478 | volume | 367 |
| Q24308699 | A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis |
| Q48739410 | A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells |
| Q55196370 | A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. |
| Q22253346 | A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis |
| Q73161644 | A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1 |
| Q40392328 | A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration |
| Q36237218 | A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motility |
| Q32019550 | Actin Polymerization Is Required for Negative Feedback Regulation of Epidermal Growth Factor-Induced Signal Transduction |
| Q24318527 | Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation |
| Q45009039 | Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP. |
| Q36335477 | Activation of alternate prosurvival pathways accounts for acquired sunitinib resistance in U87MG glioma xenografts |
| Q40015802 | Activation of phospholipase C gamma in Schizosaccharomyces pombe by coexpression of receptor or nonreceptor tyrosine kinases |
| Q27863662 | Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization |
| Q36619468 | Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF |
| Q38381918 | Additive effect by combination of Akt inhibitor, MK-2206, and PDGFR inhibitor, tyrphostin AG 1296, in suppressing anaplastic thyroid carcinoma cell viability and motility |
| Q24806905 | Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development |
| Q24306906 | Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factor |
| Q41226885 | An 11-amino acid sequence from c-met initiates epithelial chemotaxis via phosphatidylinositol 3-kinase and phospholipase C. |
| Q52125462 | An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. |
| Q44741306 | Analysis of Recombinant Human Platelet-Derived Growth Factor by Reversed-Charge Capillary Zone Electrophoresis |
| Q30454412 | Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD |
| Q24318760 | Apolipoprotein E Inhibits Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Migration and Proliferation by Suppressing Signal Transduction and Preventing Cell Entry to G1 Phase |
| Q40109529 | Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation |
| Q34170512 | Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration |
| Q36893296 | C-reactive protein and vein graft disease: evidence for a direct effect on smooth muscle cell phenotype via modulation of PDGF receptor-beta |
| Q98386021 | CD146, from a melanoma cell adhesion molecule to a signaling receptor |
| Q33875062 | CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration |
| Q43948644 | Calcium-sensing receptor-mediated activation of phospholipase C-gamma1 is downstream of phospholipase C-beta and protein kinase C in MC3T3-E1 osteoblasts |
| Q35595634 | Cell migration: a novel aspect of pancreatic stellate cell biology |
| Q27860682 | Cell migration: a physically integrated molecular process |
| Q33638611 | Cellular aspects of trophic actions in the nervous system. |
| Q34548314 | Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases |
| Q36807957 | Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B |
| Q39210209 | Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line |
| Q34103617 | Connecting signaling and cell cycle progression in growth factor-stimulated cells |
| Q28505411 | Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblasts |
| Q40163771 | Constitutive diffuse activation of phosphoinositide 3-kinase at the plasma membrane by v-Src suppresses the chemotactic response to PDGF by abrogating the polarity of PDGF receptor signalling |
| Q36255219 | Corequirement of Specific Phosphoinositides and Small GTP-binding Protein Cdc42 in Inducing Actin Assembly in Xenopus Egg Extracts |
| Q41949145 | Crenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo |
| Q44120922 | Cysteinyl leukotrienes promote human airway smooth muscle migration |
| Q40527099 | DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling |
| Q30476972 | Deterministic model of dermal wound invasion incorporating receptor-mediated signal transduction and spatial gradient sensing |
| Q35048809 | Development and characterisation of tetracycline-regulated phosphoinositide 3-kinase mutants: assessing the role of multiple phosphoinositide 3-kinases in chemokine signaling. |
| Q42442843 | Differential Effects of EGF and Amphiregulin on Adhesion Molecule Expression and Migration of Colon Carcinoma Cells |
| Q40640840 | Directional motility induced by epidermal growth factor requires Cdc42. |
| Q42477032 | Disruption of PDGFRalpha-initiated PI3K activation and migration of somite derivatives leads to spina bifida. |
| Q41431319 | Distribution and functions of platelet-derived growth factors and their receptors during embryogenesis |
| Q40738595 | Distribution of gelsolin and phosphoinositol 4,5-bisphosphate in lamellipodia during EGF-induced motility |
| Q40946341 | Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes |
| Q33952528 | Dolichol-phosphate-mannose-3 (DPM3)/prostin-1 is a novel phospholipase C-gamma regulated gene negatively associated with prostate tumor invasion |
| Q47989358 | Dual functions of the heartless fibroblast growth factor receptor in development of theDrosophila embryonic mesoderm |
| Q40718647 | EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness |
| Q41039585 | EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCγ signaling pathway |
| Q41257357 | EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism |
| Q43640432 | Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model |
| Q53736678 | Effect of platelet-activating factor receptor expression on CHO cell motility |
| Q24292157 | Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells |
| Q55332047 | Endothelial cell malignancies: new insights from the laboratory and clinic. |
| Q46872431 | Endothelin-1, an ulcer inducer, promotes gastric ulcer healing via mobilizing gastric myofibroblasts and stimulates production of stroma-derived factors |
| Q40911707 | Epidermal and hepatocyte growth factors stimulate chemotaxis in an intestinal epithelial cell line |
| Q41021037 | Epidermal growth factor alters fibroblast migration speed and directional persistence reciprocally and in a matrix-dependent manner |
| Q40595058 | Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway |
| Q36234800 | Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement |
| Q77701735 | Epidermal growth factor receptor-mediated motility in fibroblasts |
| Q41060639 | Epidermal growth factor receptor–stimulated intestinal epithelial cell migration requires phospholipase C activity |
| Q37263452 | ErbB receptors in the biology and pathology of the aerodigestive tract |
| Q43794384 | Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle |
| Q28377996 | Expression cloning of protein targets for 3-phosphorylated phosphoinositides |
| Q40875614 | Focal adhesion kinase in integrin signaling |
| Q35592844 | Focal adhesion kinase promotes phospholipase C-gamma1 activity. |
| Q96304314 | From a discrete model of chemotaxis with volume-filling to a generalized Patlak–Keller–Segel model |
| Q34459792 | Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA. |
| Q36256146 | G protein beta subunit-null mutants are impaired in phagocytosis and chemotaxis due to inappropriate regulation of the actin cytoskeleton |
| Q33834722 | Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways |
| Q77367016 | Growth Factor-Dependent Signaling and Cell Cycle Progression |
| Q33814336 | Growth factor signaling pathways in vascular development |
| Q34164593 | Growth factor-dependent signaling and cell cycle progression |
| Q43762442 | Guidance of cell migration by the Drosophila PDGF/VEGF receptor |
| Q28576171 | Identification of a phosphodiesterase I/Nucleotide pyrophosphatase-related gene mRNA in rat vascular smooth muscle cells by the differential display approach |
| Q35774099 | Identification of platelet-derived growth factor A and B chains in human renal vascular rejection |
| Q37954724 | Imatinib mesylate for the treatment of pulmonary arterial hypertension |
| Q24800145 | Implications of growth factor alterations in the treatment of pancreatic cancer |
| Q34800896 | In chemotaxing fibroblasts, both high-fidelity and weakly biased cell movements track the localization of PI3K signaling. |
| Q77807999 | In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation |
| Q33958568 | Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2. |
| Q39635580 | Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study |
| Q40968600 | Inhibition of phospholipase C-gamma1 activation blocks glioma cell motility and invasion of fetal rat brain aggregates |
| Q40717378 | Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer |
| Q41038789 | Insulin receptor substrate 1 antisense expression in an hepatoma cell line reduces cell proliferation and induces overexpression of the Src homology 2 domain and collagen protein (SHC). |
| Q43704490 | Integrin alpha(v)beta(3) is involved in stimulated migration of vascular adventitial fibroblasts by basic fibroblast growth factor but not platelet-derived growth factor |
| Q36076782 | Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases |
| Q35550381 | Internalization of Escherichia coli by human renal epithelial cells is associated with tyrosine phosphorylation of specific host cell proteins. |
| Q42442838 | Involvement of Phosphatidylinositide 3′-Kinase and Rac in Platelet-Derived Growth Factor-Induced Actin Reorganization and Chemotaxis |
| Q22254223 | Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts |
| Q57362929 | Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro |
| Q28508492 | LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation |
| Q42665478 | Leukocyte polarization in cell migration and immune interactions |
| Q47891490 | Lipid Products of Phosphoinositide 3-Kinase and Phosphatidylinositol 4′,5′-Bisphosphate Are Both Required for ADP-dependent Platelet Spreading |
| Q42817189 | Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway |
| Q44352642 | Matrix metalloproteinase-12 gene expression in human vascular smooth muscle cells |
| Q36921736 | Mechanisms of gradient detection: a comparison of axon pathfinding with eukaryotic cell migration. |
| Q34199550 | Mechanisms of platelet-derived growth factor-induced chemotaxis |
| Q38354870 | Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways |
| Q34727916 | Mesenchymal stem cell migration is regulated by fibronectin through α5β1-integrin-mediated activation of PDGFR-β and potentiation of growth factor signals |
| Q41660541 | Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells. |
| Q50423780 | Molecular Regulation of Sprouting Angiogenesis |
| Q77312778 | Morphological alterations in rat peritoneal mast cells by stem cell factor |
| Q42484381 | Motility and invasion are differentially modulated by Rho family GTPases |
| Q77931640 | Motility is rate-limiting for invasion of bladder carcinoma cell lines |
| Q41077471 | Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis |
| Q33948870 | Natural biology of polyomavirus middle T antigen |
| Q30167854 | Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton |
| Q34166170 | Over-expression of PDGFR-β promotes PDGF-induced proliferation, migration, and angiogenesis of EPCs through PI3K/Akt signaling pathway |
| Q40939773 | Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis. |
| Q40952577 | PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1. |
| Q38615308 | PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway |
| Q43122043 | PDGF-BB protects cardiomyocytes from apoptosis and improves contractile function of engineered heart tissue |
| Q28583835 | PDGF-induced glycosaminoglycan synthesis is mediated via phosphatidylinositol 3-kinase |
| Q43666385 | PI 3-kinases and Src kinases regulate spreading and migration of cultured VSMCs |
| Q79387212 | PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors |
| Q24318343 | PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration |
| Q41472008 | PLC-gamma1 regulates fibronectin assembly and cell aggregation |
| Q38991018 | PP121, a dual inhibitor of tyrosine and phosphoinositide kinases, inhibits anaplastic thyroid carcinoma cell proliferation and migration |
| Q33765703 | PTEN gene and integrin signaling in cancer |
| Q37592539 | PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis |
| Q73049448 | Phospatidylinositol 3-kinase expression in human breast cancer |
| Q43786822 | Phosphatidylinositol 3-Kinase and NF-κB Regulate Motility of Invasive MDA-MB-231 Human Breast Cancer Cells by the Secretion of Urokinase-type Plasminogen Activator |
| Q40746645 | Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration |
| Q42807111 | Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis |
| Q34135631 | Phosphatidylinositol 3-kinases in tumor progression |
| Q41174456 | Phosphatidylinositol-3' kinase is not required for mitogenesis or internalization of the Flt3/Flk2 receptor tyrosine kinase |
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| Q41099687 | Phosphoinositide kinases |
| Q37989035 | Phosphoinositides in Chemotaxis |
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| Q43715868 | Platelet-derived growth factor inhibits smooth muscle cell adhesion to fibronectin by ERK-dependent and ERK-independent pathways. |
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| Q41741259 | Signal transduction in hepatic stellate cells |
| Q42805134 | Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases. |
| Q28609164 | Signal transduction via platelet-derived growth factor receptors |
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