Thrombospondin modulates alpha v beta 3 function through integrin-associated protein

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Thrombospondin modulates alpha v beta 3 function through integrin-associated protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.135.2.533
P932PMC publication ID2121041
P698PubMed publication ID8896608

P2093author name stringBrown EJ
Frazier WA
Lindberg FP
Gao AG
Dimitry JM
P2860cites workRh-related antigen CD47 is the signal-transducer integrin-associated proteinQ24336777
pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesionsQ24561464
The properdin-like type I repeats of human thrombospondin contain a cell attachment siteQ24644415
Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1Q24672489
Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand bindingQ24673765
Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activityQ24674570
Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrinsQ24678607
Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domainsQ24680099
Integrin-associated protein is a receptor for the C-terminal domain of thrombospondinQ28272569
Integrins: emerging paradigms of signal transductionQ28283614
Identification of active peptide sequences in the carboxyl-terminal cell binding domain of human thrombospondin-1Q28294728
Vitronectin and its receptorsQ28298613
Protein kinase C involvement in focal adhesion formationQ68204402
Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase CQ69059319
Isolation and characterization of thrombospondinQ69236844
Thrombospondin mediates migration and potentiates platelet-derived growth factor-dependent migration of calf pulmonary artery smooth muscle cellsQ70501273
Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptorsQ71623372
Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human plateletsQ71650818
Identification of a receptor candidate for the carboxyl-terminal cell binding domain of thrombospondinsQ71656647
ThrombospondinsQ71694639
Biologic activities of the beta-chemokine TCA3 on neutrophils and macrophagesQ72191705
Heparin-binding peptides from thrombospondins 1 and 2 contain focal adhesion-labilizing activityQ72639618
Thrombospondin promotes chemotaxis and haptotaxis of human peripheral blood monocytesQ72727504
Thrombospondin in early human wound tissueQ28302881
Protein kinase C: structure, function, and regulationQ28618608
Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregationQ28646199
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigmQ29547181
Integrins and signal transduction pathways: the road takenQ29547895
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient miceQ29617498
Integrin function: molecular hierarchies of cytoskeletal and signaling moleculesQ29618843
Focal adhesion kinase and associated proteinsQ30465310
Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesisQ34077458
Heterotrimeric G proteins: organizers of transmembrane signalsQ34317073
Transendothelial migration of neutrophils involves integrin-associated protein (CD47)Q34399427
Induction of carcinoma cell migration on vitronectin by NF-kappa B-dependent gene expression.Q34449883
Beta 1 integrins signal lipid second messengers required during cell adhesionQ34452102
Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.Q36223338
Thrombospondin stimulates motility of human neutrophilsQ36224162
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectinQ36234780
Integrin beta 3 cytoplasmic tail is necessary and sufficient for regulation of alpha 5 beta 1 phagocytosis by alpha v beta 3 and integrin-associated proteinQ36235842
A role for phosphatidylinositol 3-kinase in the regulation of beta 1 integrin activity by the CD2 antigenQ36236297
CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epitheliaQ36236456
Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burstQ36362394
Disulfides modulate RGD-inhibitable cell adhesive activity of thrombospondinQ36531615
ThrombospondinsQ36689844
A monoclonal antibody against human thrombospondin inhibits platelet aggregationQ37688937
Pertussis toxin specifically inhibits growth cone guidance by a mechanism independent of direct G protein inactivationQ38293862
Adhesive signaling in plateletsQ40396958
Thrombospondin deposition in rat carotid artery injuryQ41137166
CD28-mediated up-regulation of beta 1-integrin adhesion involves phosphatidylinositol 3-kinase.Q41236079
Thrombospondin mediates calcium mobilization in fibroblasts via its Arg-Gly-Asp and carboxyl-terminal domainsQ41283869
Regulation of transforming growth factor-beta activation by discrete sequences of thrombospondin 1.Q41357814
Regulation of chemotaxis by the platelet-derived growth factor receptor-betaQ41488423
Motility of human carcinoma cells in response to thrombospondin: relationship to metastatic potential and thrombospondin structural domains.Q41578518
Thrombospondin modulates focal adhesions in endothelial cellsQ41585502
Inhibition of protein kinase C by calphostin C is light-dependentQ41687741
Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venulesQ42118588
Identification of a new cell adhesion motif in two homologous peptides from the COOH-terminal cell binding domain of human thrombospondin.Q42621522
Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogenQ43108382
A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells.Q43491083
Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectinQ46081423
Identification of integrin alpha 3 beta 1 as a neuronal thrombospondin receptor mediating neurite outgrowthQ46148499
Ligand-induced adhesion to activated endothelium and to vascular cell adhesion molecule-1 in lymphocytes transfected with the N-formyl peptide receptor.Q48140131
Differential expression of thrombospondin 1, 2, and 3 during murine developmentQ48292673
Activated T-cell adhesion to thrombospondin is mediated by the alpha 4 beta 1 (VLA-4) and alpha 5 beta 1 (VLA-5) integrins.Q52061975
Cell attachment activity of the carboxyl-terminal domain of human thrombospondin expressed in Escherichia coliQ54687260
Irreversible oxidative inactivation of protein kinase C by photosensitive inhibitor calphostin CQ67465312
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages12
P304page(s)533-544
P577publication date1996-10-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleThrombospondin modulates alpha v beta 3 function through integrin-associated protein
P478volume135

Reverse relations

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