| scholarly article | Q13442814 |
| P50 | author | Sebastian Pons | Q63919305 |
| P2093 | author name string | Y Zhang | |
| T Asano | |||
| M F White | |||
| X J Sun | |||
| M G Myers | |||
| M Miralpeix | |||
| T L Fisher | |||
| E Glasheen | |||
| P2860 | cites work | Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation | Q24293143 |
| Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1 | Q24304774 | ||
| Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1 | Q24305352 | ||
| 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells | Q24316333 | ||
| Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptor | Q24336489 | ||
| High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains | Q24563877 | ||
| Insulin stimulates the tyrosine phosphorylation of a 61-kilodalton protein in rat adipocytes | Q54261345 | ||
| The alpha-type 85-kDa subunit of phosphatidylinositol 3-kinase is phosphorylated at tyrosines 368, 580, and 607 by the insulin receptor. | Q54659152 | ||
| A manual sequencing method for identification of phosphorylated amino acids in phosphopeptides | Q68059576 | ||
| Characterization of an endogenous substrate of the insulin receptor in cultured cells | Q68996604 | ||
| Characterization of a 60-kilodalton substrate of the insulin receptor kinase | Q71618878 | ||
| Growth hormone stimulates tyrosine phosphorylation of insulin receptor substrate-1 | Q71660216 | ||
| Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase | Q72068658 | ||
| The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by Wortmannin | Q72108250 | ||
| Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor | Q72121269 | ||
| Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase | Q72237914 | ||
| Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin | Q72237918 | ||
| Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation | Q72465669 | ||
| JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes | Q72724702 | ||
| Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle | Q72952422 | ||
| Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells | Q72962197 | ||
| Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase | Q24629183 | ||
| Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85 | Q24629213 | ||
| Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes | Q27860600 | ||
| SH2 domains recognize specific phosphopeptide sequences | Q27860748 | ||
| Efficient selection for high-expression transfectants with a novel eukaryotic vector | Q27860810 | ||
| Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting | Q27940116 | ||
| Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein | Q28116980 | ||
| PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase | Q28244045 | ||
| Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal | Q28297924 | ||
| The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexes | Q28367583 | ||
| Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. | Q30194566 | ||
| Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells | Q30194642 | ||
| Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors | Q31169174 | ||
| The insulin receptor-related receptor. Tissue expression, ligand binding specificity, and signaling capabilities | Q34237500 | ||
| Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation | Q34325752 | ||
| Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes | Q36341587 | ||
| The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity | Q36745695 | ||
| Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton | Q36823241 | ||
| Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase | Q36824805 | ||
| IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85 | Q37276745 | ||
| Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling | Q37632364 | ||
| Activation of phosphatidylinositol 3-kinase by insulin | Q37697363 | ||
| The IRS-1 signaling system | Q40682085 | ||
| Phosphatidylinositol 3-kinase | Q40702617 | ||
| PI 3-kinase: structural and functional analysis of intersubunit interactions | Q40790710 | ||
| PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. | Q40790718 | ||
| Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling. | Q41442812 | ||
| T cell receptor-associated alpha-phosphatidylinositol 3-kinase becomes activated by T cell receptor cross-linking and requires pp56lck | Q41453795 | ||
| Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling | Q41471394 | ||
| Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. | Q41486855 | ||
| Regulation of chemotaxis by the platelet-derived growth factor receptor-beta | Q41488423 | ||
| IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells | Q41527015 | ||
| Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system | Q41560390 | ||
| Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects | Q41766807 | ||
| Expression and function of IRS-1 in insulin signal transmission. | Q42455127 | ||
| Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation | Q42796185 | ||
| Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity | Q42806818 | ||
| The insulin-elicited 60-kDa phosphotyrosine protein in rat adipocytes is associated with phosphatidylinositol 3-kinase | Q42811072 | ||
| A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor. | Q44680536 | ||
| Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules | Q45158799 | ||
| Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in Fao hepatoma cells | Q47405354 | ||
| Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene. | Q48077724 | ||
| The insulin-like growth factor I system in the rat cerebellum: developmental regulation and role in neuronal survival and differentiation. | Q52214166 | ||
| Synthesis, purification, and characterization of the cytoplasmic domain of the human insulin receptor using a baculovirus expression system. | Q52452209 | ||
| Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene | Q52507538 | ||
| Effects of wortmannin on increased glucose transport by insulin and norepinephrine in primary culture of brown adipocytes | Q54199298 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Q14887711 |
| Phosphoinositide-3-kinase regulatory subunit 3 | Q21496662 | ||
| P304 | page(s) | 4453-4465 | |
| P577 | publication date | 1995-08-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase | |
| P478 | volume | 15 |
| Q28249965 | 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain |
| Q28289491 | 4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient mice |
| Q30192879 | A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction |
| Q28569188 | A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK Is generated by alternative splicing of the p85alpha gene |
| Q42803323 | A novel 68-kDa adipocyte protein phosphorylated on tyrosine in response to insulin and osmotic shock |
| Q42734250 | A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells |
| Q29617059 | A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans |
| Q35905424 | Aggregation of the human high affinity immunoglobulin G receptor (FcgammaRI) activates both tyrosine kinase and G protein-coupled phosphoinositide 3-kinase isoforms. |
| Q42223817 | Altered p53 regulation of miR-148b and p55PIK contributes to tumor progression in colorectal cancer |
| Q35487650 | Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha |
| Q41150880 | Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages |
| Q35178694 | BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex |
| Q38338446 | Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278). |
| Q42809738 | Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo |
| Q39077958 | Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis |
| Q34012425 | Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha |
| Q33864082 | Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits |
| Q24530221 | Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin |
| Q24320517 | Cloning of human p55γ, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor |
| Q48043417 | Cloning, Tissue Expression, and Chromosomal Localization of the Mouse IRS-3 Gene |
| Q42092209 | Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes |
| Q34433101 | Differential Regulation of Phosphoinositide 3-Kinase Adapter Subunit Variants by Insulin in Human Skeletal Muscle |
| Q37376749 | Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse |
| Q39458573 | Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis. |
| Q24316112 | Disruption of IRS-2 causes type 2 diabetes in mice |
| Q44387195 | Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain |
| Q30165455 | Expression of a mutated form of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO). |
| Q28363309 | Expression of the splice variants of the p85alpha regulatory subunit of phosphoinositide 3-kinase in muscle and adipose tissue of healthy subjects and type 2 diabetic patients |
| Q42830554 | Extracellular matrix induced by TGFβ impairs insulin signal transduction in 3T3-L1 preadipose cells |
| Q31924344 | Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations |
| Q34372857 | Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library |
| Q41083088 | Heterologous pleckstrin homology domains do not couple IRS-1 to the insulin receptor. |
| Q22008497 | Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity |
| Q73150469 | Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha |
| Q41060477 | Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase |
| Q24670758 | Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma |
| Q53004815 | Identification of PI3K regulatory subunit p55γ as a novel inhibitor of vascular smooth muscle cell proliferation and neointimal formation |
| Q33778252 | Identification of a Proline-Rich Sequence in the CD2 Cytoplasmic Domain Critical for Regulation of Integrin-Mediated Adhesion and Activation of Phosphoinositide 3-Kinase |
| Q44574108 | In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs. |
| Q28589116 | Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase |
| Q24531326 | Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase |
| Q41038789 | Insulin receptor substrate 1 antisense expression in an hepatoma cell line reduces cell proliferation and induces overexpression of the Src homology 2 domain and collagen protein (SHC). |
| Q30176985 | Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain |
| Q28576668 | Insulin signal transduction in rat small intestine: role of MAP kinases in expression of mucosal hydrolases |
| Q24292020 | Insulin signalling and the regulation of glucose and lipid metabolism |
| Q33703478 | Insulin signalling: metabolic pathways and mechanisms for specificity |
| Q53433718 | Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse |
| Q42831442 | Insulin‐regulatable phosphoproteins in 3T3‐L1 adipocytes form detergent‐insoluble complexes not associated with caveolin |
| Q30175781 | Intermolecular interactions of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase. |
| Q30004215 | Interpreting cDNA sequences: some insights from studies on translation |
| Q40515603 | Involvement of phosphoinositide 3-kinase signaling pathway in chondrocytic differentiation of ATDC5 cells: application of a gene-trap mutagenesis |
| Q36891181 | Isolation and characterization of the droPIK57 gene encoding a new regulatory subunit of phosphatidylinositol 3-kinase from Drosophila melanogaster |
| Q28609580 | Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons |
| Q36738831 | KIT over-expression by p55PIK-PI3K leads to Imatinib-resistance in patients with gastrointestinal stromal tumors |
| Q36017999 | Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors |
| Q46853956 | Lower phosphoinositide 3-kinase (PI 3-kinase) activity and differential expression levels of selective catalytic and regulatory PI 3-kinase subunit isoforms in prefrontal cortex and hippocampus of suicide subjects. |
| Q90636669 | Major miRNA Involved in Insulin Secretion and Production in Beta-Cells |
| Q40746798 | Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits |
| Q50161677 | MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway |
| Q34272789 | Molecular Balance between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival |
| Q42985482 | Molecular cloning and biochemical characterization of a Drosophila phosphatidylinositol-specific phosphoinositide 3-kinase |
| Q40251781 | Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: a comparison study using DNA microarray |
| Q48018986 | Multiple Isoforms of the Regulatory Subunit for Phosphatidylinositol 3-Kinase (PI3-Kinase) Are Expressed in Neurons in the Rat Brain |
| Q24531626 | Multiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translation |
| Q48972578 | Mutant of insulin receptor substrate-1 incapable of activating phosphatidylinositol 3-kinase did not mediate insulin-stimulated maturation of Xenopus laevis oocytes |
| Q40615721 | Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling |
| Q42518882 | Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes |
| Q39602961 | PI 3-Kinase Regulatory Subunits as Regulators of the Unfolded Protein Response |
| Q52689921 | PI3K regulates intraepithelial cell positioning through Rho GTP-ases in the developing neural tube |
| Q46660251 | PI3K signaling effects in hypothalamic neurons mediated by estrogen |
| Q49689620 | PIK3R3 promotes chemotherapeutic sensitivity of colorectal cancer through PIK3R3/NF-kB/TP pathway |
| Q49922981 | PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis |
| Q43547042 | Phosphatidylinositol-3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum. |
| Q35221193 | Phosphoinositide 3-Kinase Signaling in Retinal Rod Photoreceptors |
| Q37463310 | Phosphoinositide 3-kinase signaling in the vertebrate retina |
| Q42991205 | Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling |
| Q41012564 | Phosphorylation of the Grb2- and Phosphatidylinositol 3-Kinase p85–binding p36/38 by Syk in Lck-Negative T Cells |
| Q28506865 | Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling |
| Q39456427 | Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit |
| Q33588931 | Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance |
| Q77481930 | Recent advances in the understanding of interleukin-2 signal transduction |
| Q33639166 | Recent progress in insulin signal transduction |
| Q28344700 | Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes |
| Q37536210 | Regulated expression of CXCR4 constitutive active mutants revealed the up-modulated chemotaxis and up-regulation of genes crucial for CXCR4 mediated homing and engraftment of hematopoietic stem/progenitor cells |
| Q28379354 | Regulation of the p85/p110 Phosphatidylinositol 3′-Kinase: Stabilization and Inhibition of the p110α Catalytic Subunit by the p85 Regulatory Subunit |
| Q33284331 | Role of PI3-kinase and PI4-kinase in actin polymerization during bovine sperm capacitation |
| Q48021761 | Role of binding proteins to IRS-1 in insulin signalling |
| Q30160287 | Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement |
| Q33821542 | Role of the p55-gamma subunit of PI3K in ALK-induced cell migration: RNAi-based selection of cell migration regulators |
| Q36564768 | Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways |
| Q40442177 | Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition |
| Q33855352 | Structure and function of phosphatidylinositol-3,4 kinase |
| Q52532836 | Structure and function of phosphoinositide 3-kinases |
| Q51562728 | Substrate interactions in the short- and long-term regulation of renal glucose oxidation |
| Q44920261 | Suppression subtractive hybridization and microarray identification of estrogen-regulated hypothalamic genes. |
| Q35096703 | T cell anergy and costimulation |
| Q74016240 | Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling |
| Q28284128 | The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling |
| Q35915951 | The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. |
| Q28510589 | The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation |
| Q28678835 | The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101 |
| Q40875698 | The IRS-Signaling System: A Network of Docking Proteins That Mediate Insulin and Cytokine Action |
| Q28272481 | The IRS-signalling system: a network of docking proteins that mediate insulin action |
| Q24554327 | The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest |
| Q42158506 | The N-terminal 34 residues of the 55 kDa regulatory subunits of phosphoinositide 3-kinase interact with tubulin |
| Q92950325 | The Opposing Roles of PIK3R1/p85α and PIK3R2/p85β in Cancer |
| Q28591965 | The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts |
| Q41236736 | The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system |
| Q37454384 | The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. |
| Q39576638 | The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin |
| Q58438150 | The role of PI 3-kinase in insulin action |
| Q28241699 | Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor |
| Q44617813 | Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinases |
| Q42808291 | Tyrosine phosphorylation of the juxtamembrane domain of the v-Fms oncogene product is required for its association with a 55-kDa protein |
| Q41554112 | Using structure to define the function of phosphoinositide 3‐kinase family members |
| Q36561273 | YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites |
| Q42485996 | p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity |
| Q24314825 | p110δ, a novel phosphoinositide 3-kinase in leukocytes |
| Q34550411 | p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity |
| Q39178601 | p55PIK Transcriptionally Activated by MZF1 Promotes Colorectal Cancer Cell Proliferation |
| Q53536509 | p55γ functional mimetic peptide N24 blocks vascular proliferative disorders |
| Q30176511 | p60 is an adaptor for the Drosophila phosphoinositide 3-kinase, Dp110. |
| Q30176597 | p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin |
| Q35953378 | p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis. |
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