| scholarly article | Q13442814 |
| P2093 | author name string | L Yu | |
| H Chen | |||
| J Kowalski | |||
| N Ferrara | |||
| H Gille | |||
| M T Pisabarro | |||
| T Davis-Smyth | |||
| P2860 | cites work | Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation | Q22004269 |
| Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization | Q22009127 | ||
| Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family | Q24303496 | ||
| Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases | Q24309883 | ||
| Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1 | Q24310533 | ||
| The Phosphorylated 1169-Tyrosine Containing Region of Flt-1 Kinase (VEGFR-1) Is a Major Binding Site for PLCγ | Q24312773 | ||
| Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor | Q24321564 | ||
| Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor | Q24323249 | ||
| Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1 | Q24323317 | ||
| The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor | Q24328901 | ||
| Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding | Q24336437 | ||
| Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor | Q24560244 | ||
| Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis | Q27618672 | ||
| Crystal structure of the tyrosine kinase domain of the human insulin receptor | Q27730800 | ||
| Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors | Q27777798 | ||
| Rapid and efficient site-specific mutagenesis without phenotypic selection | Q27860608 | ||
| Identification of a new endothelial cell growth factor receptor tyrosine kinase | Q28117368 | ||
| Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR | Q28238949 | ||
| Signalling through the lipid products of phosphoinositide-3-OH kinase | Q28241516 | ||
| Purification and properties of an endothelial cell growth factor from human platelets | Q28300487 | ||
| Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice | Q28504776 | ||
| Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium | Q28587604 | ||
| Vascular endothelial growth factor is a secreted angiogenic mitogen | Q28646475 | ||
| A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF | Q28646512 | ||
| Identification of Vascular Endothelial Growth Factor Receptor-1 Tyrosine Phosphorylation Sites and Binding of SH2 Domain-containing Molecules | Q28646549 | ||
| Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement | Q30014848 | ||
| Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. | Q30176860 | ||
| Sck Interacts with KDR and Flt-1 via Its SH2 Domain | Q31990276 | ||
| Role of vascular endothelial growth factor in the regulation of angiogenesis | Q33723796 | ||
| A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation | Q33890119 | ||
| A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases | Q33890319 | ||
| Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1 | Q35065442 | ||
| Activation of phosphatidylinositol 3-kinase by insulin | Q37697363 | ||
| Tyrosine 1213 of Flt-1 Is a Major Binding Site of Nck and SHP-2 | Q38337364 | ||
| Loss of the exon encoding the juxtamembrane domain is essential for the oncogenic activation of TPR-MET. | Q40937368 | ||
| Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasms | Q40973424 | ||
| The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade | Q41077200 | ||
| Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling | Q41471394 | ||
| Regulation of chemotaxis by the platelet-derived growth factor receptor-beta | Q41488423 | ||
| Characterization of the structure and function of W --> F WW domain variants: identification of a natively unfolded protein that folds upon ligand binding | Q41703944 | ||
| A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain | Q43784472 | ||
| Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis | Q46273746 | ||
| Requirements for Binding and Signaling of the Kinase Domain Receptor for Vascular Endothelial Growth Factor | Q46693604 | ||
| Flt-1, a receptor for vascular endothelial growth factor, has transforming and morphogenic potentials | Q47956941 | ||
| Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. | Q51089819 | ||
| Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. | Q55065488 | ||
| Vascular Endothelial Growth Factor-C A Growth Factor for Lymphatic and Blood Vascular Endothelial Cells | Q57382309 | ||
| The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities | Q59261168 | ||
| Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR | Q71058989 | ||
| Vascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium | Q74356095 | ||
| Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. The Children's Cancer and Leukemia Study Group, Japan | Q74524088 | ||
| Src autoinhibition: let us count the ways | Q78062284 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endothelium | Q111140 |
| P304 | page(s) | 4064-4073 | |
| P577 | publication date | 2000-08-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration | |
| P478 | volume | 19 |
| Q36121867 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin differentially suppresses angiogenic responses in human placental vein and artery endothelial cells |
| Q40559949 | A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation. |
| Q41691274 | A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation |
| Q34333820 | A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1 |
| Q34360584 | Adhesion events in angiogenesis. |
| Q24311063 | All in the family: VEGF-B joins the ranks of proangiogenic cytokines |
| Q43668422 | An inhibitory role of the phosphatidylinositol 3-kinase-signaling pathway in vascular endothelial growth factor-induced tissue factor expression |
| Q43509136 | Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants |
| Q41791633 | Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. |
| Q38930194 | Arsenite-mediated promotion of anchorage-independent growth of HaCaT cells through placental growth factor. |
| Q39745856 | Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region. |
| Q46878927 | Characterization of Endocrine Gland-derived Vascular Endothelial Growth Factor Signaling in Adrenal Cortex Capillary Endothelial Cells |
| Q35949632 | Complexity in the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF)-receptors signaling |
| Q35001515 | Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis |
| Q40710486 | Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor |
| Q77527027 | Delayed mammary gland involution in MMTV-AKT1 transgenic mice |
| Q35764454 | Differential expression of vascular endothelial growth factor (VEGF), endocrine gland derived-VEGF, and VEGF receptors in human placentas from normal and preeclamptic pregnancies |
| Q33786526 | Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis |
| Q40156352 | Effect of hypoxia on the release of vascular endothelial growth factor and testosterone in mouse TM3 Leydig cells |
| Q38497288 | Endothelial progenitor cells in tumor angiogenesis: another brick in the wall |
| Q48272397 | Enhanced expression of the Flt‐1 and Flk‐1 receptor tyrosine kinases in a newborn piglet model of ischemic tolerance |
| Q37333639 | FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? |
| Q40760923 | FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model |
| Q40759879 | Functional analysis of discoidin domain receptor 1: effect of adhesion on DDR1 phosphorylation |
| Q42376033 | Ginsenoside Rb1 prevents homocysteine-induced EPC dysfunction via VEGF/p38MAPK and SDF-1/CXCR4 activation |
| Q35791024 | Hemodynamic, vascular, and reproductive impact of FMS-like tyrosine kinase 1 (FLT1) blockade on the uteroplacental circulation during normal mouse pregnancy |
| Q36501930 | Heterotypic RPE-choroidal endothelial cell contact increases choroidal endothelial cell transmigration via PI 3-kinase and Rac1. |
| Q28590418 | Increased expression of angiogenic genes in the brains of mouse meg3-null embryos |
| Q24291630 | Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3 |
| Q48278918 | Liver Resident Macrophages (Kupffer Cells) Share Several Functional Antigens in Common with Endothelial Cells. |
| Q34331369 | Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A |
| Q38853372 | Mesonephric Cell Migration into the Gonads and Vascularization Are Processes Crucial for Testis Development |
| Q34566028 | Molecular and functional diversity of vascular endothelial growth factors |
| Q39412431 | Morphine Sulfate Inhibits Hypoxia-induced Vascular Endothelial Growth Factor Expression in Endothelial Cells and Cardiac Myocytes |
| Q48036246 | Novel FLT3 point mutations within exon 14 found in patients with acute myeloid leukaemia |
| Q100490609 | Overview of current targeted therapy in gallbladder cancer |
| Q30468335 | PDGF/VEGF system activation and angiogenesis following initial post ovariectomy meningeal microvessel loss. |
| Q38124762 | PI3K in cancer–stroma interactions: bad in seed and ugly in soil |
| Q53398020 | Peroxiredoxin II Is an Essential Antioxidant Enzyme that Prevents the Oxidative Inactivation of VEGF Receptor-2 in Vascular Endothelial Cells |
| Q64103615 | Phytochemicals Targeting VEGF and VEGF-Related Multifactors as Anticancer Therapy |
| Q38070471 | Placental trophoblast cell differentiation: Physiological regulation and pathological relevance to preeclampsia |
| Q42532910 | Regulating angiogenesis at the level of PtdIns-4,5-P2. |
| Q24304277 | Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1 |
| Q38010296 | Role of the VEGF/VEGFR Axis in Cancer Biology and Therapy |
| Q43754731 | Signal transduction by VEGF receptor-1 wild type and mutant proteins |
| Q26825677 | Signaling regulation of fetoplacental angiogenesis |
| Q44643921 | Snake Venom Vascular Endothelial Growth Factors (VEGFs) Exhibit Potent Activity through Their Specific Recognition of KDR (VEGF Receptor 2) |
| Q28363361 | Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells |
| Q24338964 | Structural and functional alterations of FLT3 in acute myeloid leukemia |
| Q34652403 | Substitution of C-terminus of VEGFR-2 with VEGFR-1 promotes VEGFR-1 activation and endothelial cell proliferation |
| Q33681817 | The Role of RPE Cell-Associated VEGF189in Choroidal Endothelial Cell Transmigration across the RPE |
| Q35376231 | The anti-angiogenic role of discoidin domain receptor 2 (DDR2) in laser-induced choroidal neovascularization |
| Q27860704 | The biology of VEGF and its receptors |
| Q26796921 | The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis |
| Q24303500 | The molecular basis of VEGFR-1 signal transduction pathways in primary human monocytes |
| Q24319174 | The role of FLT3 in haematopoietic malignancies |
| Q36390431 | The role of VEGF receptors in angiogenesis; complex partnerships |
| Q44487732 | The role of c-Fes in vascular endothelial growth factor-A-mediated signaling by endothelial cells |
| Q38089742 | Therapeutic applications of PI3K inhibitors in cardiovascular diseases |
| Q35011885 | Therapies directed at vascular endothelial growth factor |
| Q38673511 | Unlocking Doors without Keys: Activation of Src by Truncated C-terminal Intracellular Receptor Tyrosine Kinases Lacking Tyrosine Kinase Activity |
| Q34461939 | VEGF Receptor Signal Transduction |
| Q38856920 | VEGF receptor signal transduction - A brief update |
| Q37795572 | VEGF receptor signaling in vertebrate development. |
| Q29617256 | VEGF receptor signalling - in control of vascular function |
| Q34096365 | VEGF: an update on biological and therapeutic aspects |
| Q34333828 | VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy |
| Q77350511 | Vascular Endothelial Cell Growth Factor-Driven Endothelial Tube Formation Is Mediated by Vascular Endothelial Cell Growth Factor Receptor-2, a Kinase Insert Domain-Containing Receptor |
| Q28506172 | Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos |
| Q26777347 | Vascular endothelial growth factor A: just one of multiple mechanisms for sex-specific vascular development within the testis? |
| Q40382164 | Vascular endothelial growth factor acts in an autocrine manner in rhabdomyosarcoma cell lines and can be inhibited with all-trans-retinoic acid |
| Q35919917 | Vascular endothelial growth factor and the nervous system. |
| Q24305184 | Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines |
| Q35049227 | Vascular endothelial growth factor receptors: molecular mechanisms of activation and therapeutic potentials. |
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