A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation

scientific article published on 6 April 2016

A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1052759844
P356DOI10.1038/EJHG.2016.26
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/ejhg.2016.26
P932PMC publication ID4989210
P698PubMed publication ID27049304

P50authorNaveed Anjum ChikanQ59683799
Taseem A MokhdomiQ85800376
P2093author name stringAsif Amin
Asrar H Wafai
Shoiab Bukhari
Raies A Qadri
Nisar A Chowdri
Sajad H Wani
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Positive and negative modulation of angiogenesis by VEGFR1 ligandsQ37401612
Antiangiogenic and antitumoral effects mediated by a vascular endothelial growth factor receptor 1 (VEGFR-1)-targeted DNAzymeQ37446015
Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2.Q38337364
Affinity proteomics led identification of vimentin as a potential biomarker in colon cancers: insights from serological screening and computational modelling.Q38947548
A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migrationQ40392328
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Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.Q43592482
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P433issue9
P304page(s)1287-1293
P577publication date2016-04-06
P1433published inEuropean Journal of Human GeneticsQ2155433
P1476titleA novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation
P478volume24

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Q89425532Aqueous solution interactions with sex hormone-binding globulin and estradiol: a theoretical investigationcites workP2860

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