scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Qiang Ma | Q79935556 |
P2093 | author name string | A. Y. H. Lu | |
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TNFalpha promoter region gene polymorphisms in carbamazepine-hypersensitive patients. | Q33941873 | ||
N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction | Q33985340 | ||
A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans | Q34085379 | ||
Pharmacogenetics and adverse drug reactions | Q34088287 | ||
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir | Q34117815 | ||
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States | Q34165115 | ||
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Pharmacogenomics--drug disposition, drug targets, and side effects | Q34175616 | ||
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Interindividual variability in inhibition and induction of cytochrome P450 enzymes | Q34192754 | ||
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Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype | Q44960521 | ||
CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazole-based quadruple therapy for eradication of Helicobacter pylori | Q45062165 | ||
High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives | Q45887974 | ||
ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. | Q45993642 | ||
Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) trial. | Q45995789 | ||
Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans. | Q46023319 | ||
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Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics | Q46551880 | ||
A vitamin K epoxide reductase complex subunit-1 (VKORC1) mutation in a patient with vitamin K antagonist resistance | Q46566220 | ||
Genetic testing for warfarin dosing? Not yet ready for prime time | Q46787525 | ||
Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myoc | Q46868498 | ||
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression | Q46906576 | ||
Characterization of the UDP glucuronosyltransferase activity of human liver microsomes genotyped for the UGT1A1*28 polymorphism | Q46980000 | ||
Association between angiotensin-converting enzyme gene polymorphisms and regression of left ventricular hypertrophy in patients treated with angiotensin-converting enzyme inhibitors | Q48206347 | ||
Richard Weinshilboum: Pharmacogenetics: The future is here! | Q48351049 | ||
Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. | Q50899702 | ||
Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression | Q56607621 | ||
Digoxin pharmacokinetics and MDR1 genetic polymorphisms | Q57314091 | ||
Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males | Q57500331 | ||
SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid | Q57825144 | ||
Angiotensin converting enzyme gene polymorphism and ACE inhibition in diabetic nephropathy | Q59489273 | ||
Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids | Q34318910 | ||
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment | Q34381754 | ||
Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity | Q34400003 | ||
Common VKORC1 and GGCX polymorphisms associated with warfarin dose | Q34417386 | ||
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose | Q34423204 | ||
Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes | Q34477526 | ||
Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster | Q34502235 | ||
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. | Q34502241 | ||
HLA-B*5701 screening for hypersensitivity to abacavir | Q34747145 | ||
Association of warfarin dose with genes involved in its action and metabolism | Q35633802 | ||
Moving towards individualized medicine with pharmacogenomics | Q35784527 | ||
Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios | Q35860313 | ||
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Translation of the Philadelphia chromosome into therapy for CML. | Q37344094 | ||
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Targeted cancer therapies in the twenty-first century: lessons from imatinib | Q37710963 | ||
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A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury | Q42966589 | ||
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ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin | Q43174441 | ||
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In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies | Q43235385 | ||
A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel. | Q43286781 | ||
Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes | Q43445863 | ||
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Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus | Q44579589 | ||
Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics | Q44872799 | ||
The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation. | Q44899003 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | manufacturing | Q187939 |
gene | Q7187 | ||
toxicology | Q7218 | ||
pharmacogenomics | Q1152227 | ||
disease | Q12136 | ||
P5008 | on focus list of Wikimedia project | Wikimedia–NIOSH collaboration | Q104416361 |
P304 | page(s) | 437-459 | |
P577 | publication date | 2011-03-24 | |
P1433 | published in | Pharmacological Reviews | Q2085079 |
P859 | sponsor | NIOSH Health Effects Laboratory Division | Q123344455 |
P1476 | title | Pharmacogenetics, pharmacogenomics, and individualized medicine | |
P478 | volume | 63 |
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Q58762484 | A Metabolomics Approach to Pharmacotherapy Personalization |
Q28554371 | A Novel Drug-Mouse Phenotypic Similarity Method Detects Molecular Determinants of Drug Effects |
Q53176750 | A Polymorphism in the Lysyl Oxidase Propeptide Domain Accelerates Carcinogen-induced Cancer. |
Q48191729 | A Remote Assay for Measuring Canine Platelet Activation and the Inhibitory Effects of Antiplatelet Agents. |
Q90065644 | A gene-diet interaction-based score predicts response to dietary fat in the Women's Health Initiative |
Q41691274 | A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation |
Q39013355 | A one-step imaging assay to monitor cell cycle state and apoptosis in mammalian cells |
Q34322438 | A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease |
Q36670740 | A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia |
Q28078890 | Adaptive capabilities and fitness consequences associated with pollution exposure in fish |
Q36424264 | Adding Genetic Testing to Evidence-Based Guidelines to Determine the Safest and Most Effective Chronic Pain Treatment for Injured Workers |
Q38245564 | Advancing stem cell therapy from bench to bedside: lessons from drug therapies |
Q28538389 | An ontology-based, mobile-optimized system for pharmacogenomic decision support at the point-of-care |
Q36097760 | An update on the Pharmacovigilance Programme of India |
Q47715776 | Antituberculosis Drug-Induced Adverse Events in the Liver, Kidneys, and Blood: Clinical Profiles and Pharmacogenetic Predictors. |
Q26864747 | Application of routine electronic health record databases for pharmacogenetic research |
Q47203284 | Are the Origins of Precision Medicine Found in the Corpus Hippocraticum? |
Q55058713 | Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients. |
Q39950111 | Association of Genetic Polymorphisms in the VKORC1 and CYP2C9 Genes with Warfarin Dosage in a Group of Kuwaiti Individuals |
Q38542847 | Asthma Pharmacogenomics: 2015 Update |
Q38175707 | Biomarkers in rare neuromuscular diseases. |
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Q53644957 | CYP2D6 phenotype-specific codeine population pharmacokinetics. |
Q37503954 | Cell line modeling for systems medicine in cancers (review). |
Q38671265 | Clinical Trial Design in Juvenile Idiopathic Arthritis |
Q36808178 | Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder |
Q62674529 | Cloud-Based High Throughput Virtual Screening in Novel Drug Discovery |
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Q34915414 | Cometabolism of microbes and host: implications for drug metabolism and drug-induced toxicity. |
Q41078615 | Comparative analysis between saliva and buccal swabs as source of DNA: lesson from HLA-B*57:01 testing. |
Q35923793 | Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers |
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Q48310481 | DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer. |
Q33987606 | Deciphering next-generation pharmacogenomics: an information technology perspective |
Q30353144 | Differences in the origin of philosophy between Chinese medicine and Western medicine: Exploration of the holistic advantages of Chinese medicine. |
Q41747771 | Direct PCR: a new pharmacogenetic approach for the inexpensive testing of HLA-B*57:01. |
Q55315083 | Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy. |
Q24600166 | Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects |
Q37715233 | Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective |
Q35549639 | Distribution of the most Common Genetic Variants Associated with a Variable Drug Response in the Population of the Republic of Macedonia. |
Q92323624 | Diversity in the Era of Precision Medicine - From Bench to Bedside Implementation |
Q38899401 | Do SLCO1B3 (T334G) and CYP3A5*3 polymorphisms affect response in Egyptian chronic myeloid leukemia patients receiving imatinib therapy? |
Q28073025 | Economic Evaluation of Pharmacogenetic Tests in Patients Subjected to Renal Transplantation: A Review of Literature |
Q33420396 | Effect of GSTP1 and ABCC4 gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-5-fluorouracil-based chemotherapy in Bangladeshi breast cancer patients |
Q83517464 | Effect of age and gender on pharmacokinetics and pharmacodynamics of a single ticagrelor dose in healthy individuals |
Q49557489 | Effectiveness of continuous epidural analgesia on acute herpes zoster and postherpetic neuralgia: A retrospective study. |
Q35832664 | Electrocatalysis by subcellular liver fractions bound to carbon nanostructures for stereoselective green drug metabolite synthesis. |
Q64933146 | Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro. |
Q37948826 | Epidemiology and characteristics of adverse drug reactions caused by drug-drug interactions. |
Q35043079 | Evolutionary Diagnosis of non-synonymous variants involved in differential drug response |
Q38897899 | Factors affecting warfarin dose requirements and quality of anticoagulation in adult Egyptian patients: role of gene polymorphism |
Q40929491 | Frequencies of EGFR single nucleotide polymorphisms in non-small cell lung cancer patients and healthy individuals in the Republic of Serbia: a preliminary study |
Q57794673 | Frequencies of poor metabolizer alleles of 12 pharmacogenomic actionable genes in Punjabi Sikhs of Indian Origin |
Q33683604 | Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver |
Q36354529 | Genetic Polymorphisms Analysis of Pharmacogenomic VIP Variants in Miao Ethnic Group of Southwest China. |
Q38227080 | Genetic markers for prediction of treatment outcomes in ovarian cancer. |
Q49612685 | Genetic polymorphisms of CYP2C9, CYP2C19, and CYP3A5 in Kosovar population. |
Q47564586 | Genetic variation in human drug-related genes. |
Q35638586 | Genetics and tailored therapy in cardiovascular disease |
Q28554426 | Genome Sequence Variability Predicts Drug Precautions and Withdrawals from the Market |
Q30795448 | Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases |
Q38774369 | Genomic translational research: Paving the way to individualized cardiac functional analyses and personalized cardiology |
Q44404784 | Genomics and drug discovery |
Q24282581 | Genomics and the Nature of Behavioral and Social Risk |
Q38192063 | Global pharmacogenomics: where is the research taking us? |
Q93068560 | Herbal Remedies: Throwing Off Phenotype Prediction-A Culprit for Pharmacogenomic-Guided Drug Therapy and Drug Safety |
Q92061917 | High Content Solid Dispersions for Dose Window Extension: A Basis for Design Flexibility in Fused Deposition Modelling |
Q91843143 | Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study |
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Q38811685 | How polymorphisms of the cytochrome P450 genes affect ibuprofen and diclofenac metabolism and toxicity |
Q38874111 | Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine. |
Q38651234 | Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region. |
Q30383865 | Impact of germline and somatic missense variations on drug binding sites |
Q91906258 | Inconsistency in race and ethnic classification in pharmacogenetics studies and its potential clinical implications |
Q39041940 | Incorporating Pharmacogenomics into Health Information Technology, Electronic Health Record and Decision Support System: An Overview |
Q33613526 | Increased genetic diversity of ADME genes in African Americans compared with their putative ancestral source populations and implications for pharmacogenomics |
Q28070574 | Individualization of antiretroviral therapy--pharmacogenomic aspect |
Q62659072 | Intraethnic variation in steroid-5-alpha-reductase polymorphisms in prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment |
Q37329568 | Intron 4 VNTR (4a/b) polymorphism of the endothelial nitric oxide synthase gene is associated with breast cancer in Mexican women |
Q57011994 | Is It Time for a Metagenomic Basis of Therapeutics? |
Q39096673 | Is there a role for MDR1, EPHX1 and protein Z gene variants in modulation of warfarin dosage? a study on a cohort of the Egyptian population. |
Q38769814 | Ivabradine for the treatment of chronic heart failure |
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Q38497838 | Malaria medicines: a glass half full? |
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Q35934555 | NAT2 variants are associated with drug-induced liver injury caused by anti-tuberculosis drugs in Indonesian patients with tuberculosis |
Q33759731 | Nature, Nurture, and Expertise |
Q37000847 | Non-synonymous single-nucleotide variations of the human oxytocin receptor gene and autism spectrum disorders: a case-control study in a Japanese population and functional analysis. |
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