Patient Characteristics are not Associated with Clinically Important Differential Response to Dapagliflozin: a Staged Analysis of Phase 3 Data

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Patient Characteristics are not Associated with Clinically Important Differential Response to Dapagliflozin: a Staged Analysis of Phase 3 Data is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1025585539
P356DOI10.1007/S13300-014-0090-Y
P932PMC publication ID4269640
P698PubMed publication ID25502227
P5875ResearchGate publication ID269712068

P2093author name stringSusan Grandy
Angelo Del Parigi
Jennifer Sugg
Sarah Bujac
Tom Liptrot
Anne-Marie Boothman
Chris Chamberlain
Martin Karpefors
P2860cites workDapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo-controlled study.Q51332473
Dapagliflozin monotherapy in drug-naïve patients with diabetes: a randomized-controlled trial of low-dose range.Q51354355
Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: a randomized trial.Q51359456
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial.Q51372081
Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)Q57412648
Greedy function approximation: A gradient boosting machineQ57532752
The safety, efficacy and predictors for HbA1c reduction of sitagliptin in the treatment of Japanese type 2 diabetesQ82359377
Pharmacogenetics, pharmacogenomics, and individualized medicineQ23919667
Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trialQ34153496
Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trialQ34593046
Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trialQ35179843
Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapyQ36047253
Predictive models for type 2 diabetes onset in middle-aged subjects with the metabolic syndromeQ37028898
Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetesQ37139427
Ethnic differences in cardiovascular drug response: potential contribution of pharmacogeneticsQ37276490
Glucose control by the kidney: an emerging target in diabetesQ37424426
Development of the sodium-glucose co-transporter 2 inhibitor dapagliflozin for the treatment of patients with type 2 diabetes mellitusQ37960123
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trialQ42977455
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metforminQ44653784
Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trialQ46595958
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P304page(s)471-482
P577publication date2014-12-12
P1433published inDiabetes TherapyQ26853803
P1476titlePatient Characteristics are not Associated with Clinically Important Differential Response to Dapagliflozin: a Staged Analysis of Phase 3 Data
P478volume5

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cites work (P2860)
Q39707501Baseline factors associated with glycaemic response to treatment with once-weekly dulaglutide in patients with type 2 diabetes
Q64999166Feature Selection in Predictive Modeling: A Systematic Study on Drug Response Heterogeneity for Type II Diabetic Patients.
Q64929185Letter: Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors (Diabetes Metab J 2019;43:158-73).
Q31157922Machine Learning and Data Mining Methods in Diabetes Research
Q48131390Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-Term Glycemic Response to DPP-4 Inhibitor Therapy.
Q64230805Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors
Q98778627Sodium-glucose cotransporter type 2 inhibitors for the treatment of type 2 diabetes mellitus

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