A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans

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A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1002780027
P356DOI10.1038/CLPT.2009.291
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/clpt.2009.291
P932PMC publication ID2928561
P698PubMed publication ID20200517
P5875ResearchGate publication ID41722325

P50authorPaul RidkerQ7153226
P2093author name stringH L McLeod
C R King
R D Miller
S R Patel
B F Gage
C S Eby
E Deych
P E Milligan
L H Cavallari
G R Grice
R Porche-Sorbet
D Voora
D C Koboldt
M Crankshaw
P A Lenzini
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The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol.Q53233863
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Combined genetic profiles of components and regulators of the vitamin K-dependent gamma-carboxylation system affect individual sensitivity to warfarinQ82627288
Multiple Rare Alleles Contribute to Low Plasma Levels of HDL CholesterolQ22337068
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Optimal INR for prevention of stroke and death in atrial fibrillation: a critical appraisalQ28195525
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Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedic patients.Q34061511
Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolismQ34179254
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.Q34385127
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A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarizationQ34519498
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Association of warfarin dose with genes involved in its action and metabolismQ35633802
siRNA silencing of calumenin enhances functional factor IX productionQ35848852
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance doseQ36835176
Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfectionQ36914625
VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-AmericansQ36982736
The largest prospective warfarin-treated cohort supports genetic forecastingQ37071087
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarinQ37196787
Dosing anticoagulant therapy with coumarin drugs: is genotyping clinically useful? Yes.Q37216750
Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-AmericansQ37376879
P433issue4
P407language of work or nameEnglishQ1860
P921main subject(RS)-warfarinQ407431
P304page(s)445-451
P577publication date2010-03-03
P1433published inClinical Pharmacology & TherapeuticsQ1101529
P1476titleA polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans
P478volume87

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