| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Gunay Aliyeva | Q88170221 |
| Chingiz Asadov | Q67681377 | ||
| P2093 | author name string | Kamala Mustafayeva | |
| P2860 | cites work | Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia | Q77829042 |
| The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia | Q80583043 | ||
| Thiopurine S-methyltransferase genotype-phenotype concordance: used as a quality assurance tool to help control the phenotype assay | Q83227019 | ||
| Divergent activities of human glutathione transferases in the bioactivation of azathioprine | Q83825841 | ||
| Rapid genotyping of common deficient thiopurine S-methyltransferase alleles using the DNA-microchip technique | Q83840951 | ||
| Complete sequence-based screening of TPMT variants in the Korean population | Q86485715 | ||
| Pharmacogenetics, pharmacogenomics, and individualized medicine | Q23919667 | ||
| Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity | Q24674721 | ||
| Structure and dynamics of thioguanine-modified duplex DNA | Q27639874 | ||
| NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity | Q28115755 | ||
| Pharmacogenetics, drug-metabolizing enzymes, and clinical practice | Q28263284 | ||
| Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis | Q28280113 | ||
| Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance | Q28307567 | ||
| Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease | Q28362619 | ||
| Human thiopurine methyltransferase activity varies with red blood cell age | Q28365897 | ||
| Thiopurine S-methyltransferase activity in human erythrocytes: a new HPLC method using 6-thioguanine as substrate | Q74816836 | ||
| The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations | Q77341180 | ||
| Long-term results of TPMT activity monitoring in azathioprine-treated renal allograft recipients | Q31781577 | ||
| Highly multiplexed genotyping of thiopurine s-methyltransferase variants using MALD-TOF mass spectrometry: reliable genotyping in different ethnic groups | Q33358619 | ||
| Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus | Q33882066 | ||
| Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia | Q33891379 | ||
| Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: a systematic review | Q33937816 | ||
| Enzymatic deficiency in primaquine-sensitive erythrocytes | Q33969317 | ||
| Drug reactions enzymes, and biochemical genetics | Q33969557 | ||
| Thiopurines: factors influencing toxicity and response | Q34094334 | ||
| Mutation in the ITPA gene predicts intolerance to azathioprine | Q34372207 | ||
| A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia | Q34433052 | ||
| Inherited NUDT15 variant is a genetic determinant of mercaptopurine intolerance in children with acute lymphoblastic leukemia | Q34459885 | ||
| Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia | Q34513265 | ||
| Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine | Q34755513 | ||
| Moving towards individualized medicine with pharmacogenomics | Q35784527 | ||
| Pharmacogenetics and drug development: the path to safer and more effective drugs | Q35889605 | ||
| The thiopurines: an update | Q36305435 | ||
| High-resolution melting analysis of the TPMT gene: a study in the Polish population. | Q36553971 | ||
| Pharmacokinetic and pharmacodynamic variability: a daunting challenge in drug therapy | Q36737738 | ||
| Nomenclature for alleles of the thiopurine methyltransferase gene | Q37056505 | ||
| TPMT genetic variations in populations of the Russian Federation. | Q37477625 | ||
| Implementation of TPMT testing | Q37678056 | ||
| Thiopurine S-methyltransferase (TPMT) assessment prior to starting thiopurine drug treatment; a pharmacogenomic test whose time has come | Q37721661 | ||
| Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease | Q37769185 | ||
| Pre-analytic and analytic sources of variations in thiopurine methyltransferase activity measurement in patients prescribed thiopurine-based drugs: A systematic review | Q37852826 | ||
| Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease | Q37952248 | ||
| Role of thiopurine metabolite testing and thiopurine methyltransferase determination in pediatric IBD. | Q38071522 | ||
| Getting the best out of thiopurine therapy: thiopurine S-methyltransferase and beyond | Q38326107 | ||
| Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease. | Q38417177 | ||
| Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population | Q39042848 | ||
| Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes | Q41081740 | ||
| Optimizing therapy with 6-mercaptopurine and azathioprine: to measure or not to measure? | Q41174990 | ||
| Frequency of thiopurine S-methyltransferase (TPMT) alleles in southeast Iranian population. | Q43090959 | ||
| Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update | Q43221642 | ||
| Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population. | Q43254531 | ||
| Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese | Q43598169 | ||
| Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK. | Q44049360 | ||
| Characterisation of novel defective thiopurine S-methyltransferase allelic variants. | Q44058064 | ||
| Thiopurine methyltransferase polymorphisms in a multiracial asian population and children with acute lymphoblastic leukemia | Q44079899 | ||
| Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease | Q44148231 | ||
| Is thiopurine methyltransferase genetic polymorphism a major factor for withdrawal of azathioprine in rheumatoid arthritis patients? | Q44267849 | ||
| In vitro characterization of four novel non-functional variants of the thiopurine S-methyltransferase | Q44588205 | ||
| A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations | Q44766550 | ||
| Phenotype and genotype for thiopurine methyltransferase activity in the French Caucasian population: impact of age. | Q44800151 | ||
| Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). | Q44914021 | ||
| Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants | Q44958927 | ||
| Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients | Q45062041 | ||
| Whose TPMT activity is it anyway? | Q45180238 | ||
| Identification and functional analysis of two rare allelic variants of the thiopurine S-methyltransferase gene, TPMT*16 and TPMT*19. | Q45225374 | ||
| Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects | Q45287297 | ||
| Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases. | Q45938812 | ||
| Distribution of TPMT risk alleles for thiopurine [correction of thioupurine] toxicity in the Israeli population | Q46219969 | ||
| Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia | Q46398603 | ||
| Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT*2 - *24). | Q46425354 | ||
| Fatal myelotoxicity after azathioprine treatment. | Q46502266 | ||
| Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy | Q46705966 | ||
| Phenotyping and genotyping studies of thiopurine S-methyltransferase in Kazaks | Q46717317 | ||
| Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice. | Q46737694 | ||
| Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study | Q46743915 | ||
| Thiopurine S-methyltransferase pharmacogenetics: variant allele functional and comparative genomics | Q46748519 | ||
| Determination of intra-ethnic differences in the polymorphisms of thiopurine S-methyltransferase in Chinese | Q46751480 | ||
| The role of xanthine oxidase in thiopurine metabolism: a case report | Q46878740 | ||
| Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: differences in enzyme activity. | Q50593742 | ||
| Paradoxical elevated thiopurine S-methyltransferase activity after pancytopenia during azathioprine therapy: potential influence of red blood cell age. | Q50647126 | ||
| Whole-blood thiopurine S-methyltransferase activity with genotype concordance: a new, simplified phenotyping assay. | Q50718452 | ||
| Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. | Q50737060 | ||
| Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties | Q52162405 | ||
| Differential effects of targeted disruption of thiopurine methyltransferase on mercaptopurine and thioguanine pharmacodynamics. | Q52579212 | ||
| Pyrosequencing of TPMT alleles in a general Swedish population and in patients with inflammatory bowel disease. | Q54739013 | ||
| Pancytopenia related to azathioprine--an enzyme deficiency caused by a common genetic polymorphism: a review | Q55038165 | ||
| Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia | Q68092294 | ||
| Thiopurine methyltransferase isozymes in human renal tissue | Q68168887 | ||
| Concurrent unilateral chromatid damage and DNA strand breakage in response to 6-thioguanine treatment | Q68907318 | ||
| Pharmacogenetics of human thiopurine methyltransferase: kidney-erythrocyte correlation and immunotitration studies | Q70375962 | ||
| Thiopurine methyltransferase biochemical genetics: human lymphocyte activity | Q70505455 | ||
| Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults | Q70905277 | ||
| Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism | Q71656342 | ||
| Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis | Q73554499 | ||
| Enhanced bioavailability of azathioprine compared to 6-mercaptopurine therapy in inflammatory bowel disease: correlation with treatment efficacy | Q74128874 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial | Q6936496 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | genetics | Q7162 |
| enzyme | Q8047 | ||
| biomarker | Q864574 | ||
| pharmacogenetics | Q1358521 | ||
| drug allergy | Q2068896 | ||
| inborn errors of purine–pyrimidine metabolism | Q3281375 | ||
| pharmaceutical preparation | Q66089252 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 23-30 | |
| P577 | publication date | 2017-11-01 | |
| 2017-11-08 | |||
| P1433 | published in | Cardiovascular & hematological agents in medicinal chemistry | Q27721058 |
| P1476 | title | Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods | |
| P478 | volume | 15 |
| Q47105115 | Avoidance of Harm From Treatment for ANCA-Associated Vasculitis |
| Q97590549 | Gene variants and treatment outcomes in antineutrophil cytoplasmic antibody-associated vasculitis |
| Q89822227 | Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn's Disease |
| Q59334987 | SeqVItA: Sequence Variant Identification and Annotation Platform for Next Generation Sequencing Data |
| Q64065133 | The genetic vulnerability to cisplatin ototoxicity: a systematic review |
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