scholarly article | Q13442814 |
P50 | author | David C. Christiani | Q30069760 |
Daniel Haber | Q5217393 | ||
P2093 | author name string | Daphne W Bell | |
Raffaella Sordella | |||
Ross A Okimoto | |||
Brian W Brannigan | |||
David N Louis | |||
Jeffrey G Supko | |||
Frank G Haluska | |||
Thomas J Lynch | |||
Patricia L Harris | |||
Sara M Haserlat | |||
Jeff Settleman | |||
Sarada Gurubhagavatula | |||
P2860 | cites work | Mutations of the BRAF gene in human cancer | Q27860760 |
P433 | issue | 21 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | lung cancer | Q47912 |
P304 | page(s) | 2129-39 | |
P577 | publication date | 2004-05-20 | |
P1433 | published in | The New England Journal of Medicine | Q582728 |
P1476 | title | Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib | |
P478 | volume | 350 |
Q64235327 | Q64235327 |
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Q28082181 | Afatinib for the treatment of metastatic non-small cell lung cancer |
Q35273471 | Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A |
Q91328931 | Afatinib plus bevacizumab combination after acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: Multicenter, single-arm, phase 2 trial (ABC Study) |
Q27852787 | Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial |
Q38809376 | Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial |
Q38646686 | Afatinib-based combination regimens for the treatment of solid tumors: rationale, emerging strategies and recent progress |
Q42465729 | Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer |
Q39663675 | Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases |
Q88682212 | Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer |
Q38805618 | Alectinib for treatment of ALK-positive non-small-cell lung cancer |
Q90814523 | Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer |
Q40437197 | Algorithm for codevelopment of new drug-predictive biomarker combinations: accounting for inter- and intrapatient tumor heterogeneity |
Q55104021 | Algorithm for the treatment of advanced or metastatic squamous non-small-cell lung cancer: an evidence-based overview. |
Q52087873 | Aligning the stakeholders. |
Q91949987 | All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells |
Q24811573 | Allele-specific amplification in cancer revealed by SNP array analysis |
Q27851396 | Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer |
Q92633975 | Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer |
Q38465098 | Allosteric therapies for lung cancer |
Q36973814 | Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
Q51072877 | Alteration of the E-cadherin/β-catenin complex predicts poor response to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment. |
Q36669872 | Alterations in EGFR and related genes following neo-adjuvant chemotherapy in Chinese patients with non-small cell lung cancer |
Q37724576 | Alterations in VHL as potential biomarkers in renal-cell carcinoma |
Q51503951 | Alterations in cathepsin L expression in lung cancers. |
Q33411775 | Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines |
Q42002748 | Altered trafficking of mutated growth factor receptors and their associated molecules: implication for human cancers |
Q34535276 | Alveolar type II cells possess the capability of initiating lung tumor development |
Q54124211 | Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis. |
Q33731181 | Amphiregulin promotes BAX inhibition and resistance to gefitinib in non-small-cell lung cancers. |
Q35964699 | Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers |
Q24541450 | Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752 |
Q41837923 | Amplification of chromosome 8 genes in lung cancer |
Q48462937 | Amplification of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situ hybridization: association with clinicopathological features and patient survival. |
Q46906937 | Amplification of the urokinase gene and the sensitivity of prostate cancer cells to urokinase inhibitors. |
Q47116010 | Amylase-Producing Lung Cancer with a Positive Epidermal Growth Factor Receptor Mutation Treated With Gefitinib: A Case Report |
Q36228469 | An Analysis of EGFR Mutations among 1506 Cases of Non-Small Cell Lung Cancer Patients in Guangxi, China. |
Q42695763 | An Architecture for Genomics Analysis in a Clinical Setting Using Galaxy and Docker |
Q33890958 | An EGFR autocrine loop encodes a slow-reacting but dominant mode of mechanotransduction in a polarized epithelium. |
Q37137440 | An Evidence-Based Approach to the Use of Predictive Biomarkers in the Treatment of Non- Small Cell Lung Cancer (NSCLC). |
Q47135621 | An Immunohistochemical Study of Anaplastic Lymphoma Kinase and Epidermal Growth Factor Receptor Mutation in Non-Small Cell Lung Carcinoma |
Q64053000 | An Integrated Next-Generation Sequencing System for Analyzing DNA Mutations, Gene Fusions, and RNA Expression in Lung Cancer |
Q39009616 | An activation of LC3A-mediated autophagy contributes to de novo and acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma |
Q24293598 | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor |
Q39684120 | An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies |
Q53287085 | An early event of EGFR mutation in pleomorphic carcinoma of the lung. |
Q53139955 | An epidermal growth factor receptor exon 19 mutation in a mucin-producing gastric cancer sample from a Chinese patient. |
Q54634908 | An epidermal growth factor receptor intron 1 polymorphism in healthy women in Poland. |
Q36597042 | An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance |
Q53158256 | An evaluation study of EGFR mutation tests utilized for non-small-cell lung cancer in the diagnostic setting. |
Q37690880 | An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models |
Q55053711 | An improved cell membrane chromatography method for the simultaneous screening of two epidermal growth factor receptor antagonists from radix scutellariae. |
Q40783190 | An in silico analytical study of lung cancer and smokers datasets from gene expression omnibus (GEO) for prediction of differentially expressed genes |
Q35237394 | An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance |
Q35872681 | An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer |
Q48165470 | An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors |
Q53587222 | An open-label, single-dose, phase 1 study of the absorption, metabolism and excretion of quizartinib, a highly selective and potent FLT3 tyrosine kinase inhibitor, in healthy male subjects, for the treatment of acute myeloid leukemia. |
Q44736272 | An overview of Cancer's special issue on lung cancer in China |
Q36043195 | An overview of lung cancer genomics and proteomics |
Q92884879 | An unbiased in vitro screen for activating epidermal growth factor receptor mutations |
Q38077494 | An update on molecularly targeted therapies in second- and third-line treatment in non-small cell lung cancer: focus on EGFR inhibitors and anti-angiogenic agents |
Q34857289 | Analogues and derivatives of oncrasin-1, a novel inhibitor of the C-terminal domain of RNA polymerase II and their antitumor activities |
Q42551719 | Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer. |
Q36439434 | Analysis of BIM (BCL-2 like 11 gene) deletion polymorphism in Chinese non-small cell lung cancer patients |
Q46408397 | Analysis of EGFR gene amplification, protein over-expression and tyrosine kinase domain mutation in recurrent glioblastoma |
Q33598423 | Analysis of EGFR mutation status in tissue and plasma for predicting response to EGFR-TKIs in advanced non-small-cell lung cancer |
Q39371891 | Analysis of EGFR, EML4-ALK, KRAS, and c-MET mutations in Chinese lung adenocarcinoma patients |
Q35058437 | Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases |
Q39308117 | Analysis of bypass signaling in EGFR pathway and profiling of bypass genes for predicting response to anticancer EGFR tyrosine kinase inhibitors |
Q88729591 | Analysis of circulating tumor DNA: The next paradigm shift in detection and treatment of lung cancer |
Q28472663 | Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling |
Q26797471 | Analysis of different HER-2 mutations in breast cancer progression and drug resistance |
Q50936062 | Analysis of driver mutations in female non-smoker Asian patients with pulmonary adenocarcinoma. |
Q34522964 | Analysis of growth factor signaling in genetically diverse breast cancer lines |
Q37702099 | Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions. |
Q37119867 | Analysis of the benefit of sequential cranial radiotherapy in patients with EGFR mutant non-small cell lung cancer and brain metastasis |
Q50947169 | Analytic inquiry: Molecular testing in lung cancer. |
Q41348195 | Analyzing the Sensitivity of EGFR-L861Q Mutation to TKIs and A Case Report |
Q37952236 | Anaplastic lymphoma kinase as a new target for the treatment of non-small-cell lung cancer. |
Q54367113 | Anaplastic lymphoma kinase gene rearrangements in cytological samples of non-small cell lung cancer: comparison with histological assessment. |
Q27851588 | Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer |
Q50955739 | Anaplastic lymphoma kinase translocation is correlated with anaplastic lymphoma kinase expression and mutually exclusive with epidermal growth factor receptor mutation in Taiwanese non-small cell lung cancer. |
Q34283623 | Androgen metabolism in prostate cancer: from molecular mechanisms to clinical consequences |
Q36104939 | Angiogenesis and prostate cancer: important laboratory and clinical findings |
Q57023042 | Ankyrin Repeat Domain 1 Overexpression is Associated with Common Resistance to Afatinib and Osimertinib in EGFR-mutant Lung Cancer |
Q35631966 | Annotation of human cancers with EGFR signaling-associated protein complexes using proximity ligation assays |
Q53121293 | Anti PD-L1 combined with other agents in non-small cell lung cancer: combinations with non-immuno-oncology agents. |
Q38832105 | Anti-EGFR Agents: Current Status, Forecasts and Future Directions. |
Q38876644 | Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib |
Q34088265 | Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action? |
Q36321894 | Anti-epidermal growth factor receptor (EGFR) antibodies overcome resistance of ovarian cancer cells to targeted therapy and natural cytotoxicity |
Q37293327 | Anti-epidermal growth factor receptor strategies for advanced breast cancer |
Q28729071 | Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells |
Q41612476 | Anti-tumor efficacy of theliatinib in esophageal cancer patient-derived xenografts models with epidermal growth factor receptor (EGFR) overexpression and gene amplification |
Q38086799 | Anti-vascular endothelial growth factor therapy in the era of personalized medicine |
Q55509033 | Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase. |
Q34132010 | Antibody-based proteomics: fast-tracking molecular diagnostics in oncology. |
Q46836125 | Antibody-based targeted therapy for gastric cancer |
Q40133703 | Antibody-dependent cellular cytotoxicity of cetuximab against tumor cells with wild-type or mutant epidermal growth factor receptor |
Q36466443 | Anticipating clinical resistance to target-directed agents : the BCR-ABL paradigm |
Q36612420 | Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer |
Q90283381 | Antitumor Activity of a Novel Tyrosine Kinase Inhibitor AIU2001 Due to Abrogation of the DNA Damage Repair in Non-Small Cell Lung Cancer Cells |
Q39980200 | Antitumor activity of a novel EGFR tyrosine kinase inhibitor against human lung carcinoma in vitro and in vivo |
Q36448279 | Antitumor activity of motesanib alone and in combination with cisplatin or docetaxel in multiple human non-small-cell lung cancer xenograft models |
Q36413281 | Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice. |
Q64070319 | Apatinib preferentially inhibits PC9 gefitinib-resistant cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway |
Q37605160 | Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics |
Q35480110 | Apoptosis-inducing effects of cetuximab combined with radiotherapy and hypothermia on human nasopharyngeal carcinoma CNE cells |
Q27016160 | Apoptotic agents |
Q33235709 | Application of DETECTER, an evolutionary genomic tool to analyze genetic variation, to the cystic fibrosis gene family |
Q37197507 | Application of PCR methods to evaluate EGFR, KRAS and BRAF mutations in a small number of tumor cells in cytological material from lung cancer patients |
Q64099108 | Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma |
Q38170457 | Application of genotype-guided cancer therapy in solid tumors |
Q37204679 | Applications of genomics in melanoma oncogene discovery |
Q36753505 | Applications of molecular techniques to fine-needle aspiration biopsy |
Q33687963 | Applying new clinicopathological characteristics to prognostication in advanced thyroid carcinoma |
Q36900109 | Applying the discovery of the Philadelphia chromosome |
Q36045981 | Approaches to optimize the use of monoclonal antibodies to epidermal growth factor receptor |
Q36502531 | Appropriate use of tumour biomarkers for treatment with innovative drugs: A retrospective study |
Q38989374 | Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview |
Q37564967 | Are TKIs favourable for the elderly with non-small-cell lung cancer? |
Q37351965 | Are We Making Personalized Cancer Care Less Personalized? |
Q37976288 | Array-based pharmacogenomics of molecular-targeted therapies in oncology. |
Q33555207 | Ascites-derived pancreatic ductal adenocarcinoma primary cell cultures as a platform for personalised medicine |
Q35535953 | Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors |
Q43061603 | Assessing the roles of EGFR gene copy number, protein expression and mutation in predicting outcomes in non-small-cell lung cancer after treatment with EGFR inhibitors |
Q42204388 | Assessment of DDR2, BRAF, EGFR and KRAS mutations as therapeutic targets in non-adenocarcinoma lung cancer patients |
Q36946796 | Assessment of cytology based molecular analysis to guide targeted therapy in advanced non-small-cell lung cancer |
Q35584933 | Assessment of epidermal growth factor receptor and K-ras mutation status in cytological stained smears of non-small cell lung cancer patients: correlation with clinical outcomes |
Q37121410 | Assessment of epidermal growth factor receptor mutation/copy number and K-ras mutation in esophageal cancer |
Q37052272 | Assessment of epidermal growth factor receptor status in glioblastomas |
Q53126969 | Assessment of protein expression and gene status of human epidermal growth factor receptor (HER) family molecules in ameloblastomas. |
Q55299188 | Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib. |
Q37274280 | Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer |
Q53094070 | Assessment of the clinical application of detecting EGFR, KRAS, PIK3CA and BRAF mutations in patients with non-small cell lung cancer using next-generation sequencing. |
Q54965644 | Assessment of very early response evaluation with 18F-FDG-PET/CT predicts survival in erlotinib treated NSCLC patients-A comparison of methods. |
Q28550377 | Association Study of a Functional Variant on ABCG2 Gene with Sunitinib-Induced Severe Adverse Drug Reaction |
Q64983153 | Association between EGFR mutation and expression of BRCA1 and RAP80 in non-small cell lung cancer. |
Q90221713 | Association between EGFR/KRAS mutation and expression of VEGFA, VEGFR and VEGFR2 in lung adenocarcinoma |
Q36526428 | Association between GABA(A) receptor subunit gene cluster and zolpidem-induced complex sleep behaviors in Han Chinese. |
Q40406762 | Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations |
Q43131701 | Association between epidermal growth factor receptor mutations and the expression of excision repair cross-complementing protein 1 and ribonucleotide reductase subunit M1 mRNA in patients with non-small cell lung cancer |
Q83856059 | Association between vascular-poor area of primary tumors and epidermal growth factor receptor gene status in advanced lung adenocarcinoma |
Q54520157 | Association of ABCB1 polymorphisms with erlotinib pharmacokinetics and toxicity in Japanese patients with non-small-cell lung cancer. |
Q37569995 | Association of BIM Deletion Polymorphism and BIM-γ RNA Expression in NSCLC with EGFR Mutation. |
Q89602661 | Association of Divergent Carcinoembryonic Antigen Patterns and Lung Cancer Progression |
Q54310972 | Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma. |
Q37641038 | Association of EGFR mutations with low BRCA1 gene expression in non-small cell lung cancer |
Q27851860 | Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas |
Q54343399 | Association of POLK polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients. |
Q53269068 | Association of diffuse, random pulmonary metastases, including miliary metastases, with epidermal growth factor receptor mutations in lung adenocarcinoma. |
Q41862336 | Association of epidermal growth factor receptor and K-Ras mutations with smoking history in non-small cell lung cancer patients |
Q40080780 | Association of genetic variability in enzymes metabolizing chemotherapeutic agents with treatment response in head and neck cancer cases |
Q90335241 | Association with PD-L1 Expression and Clinicopathological Features in 1000 Lung Cancers: A Large Single-Institution Study of Surgically Resected Lung Cancers with a High Prevalence of EGFR Mutation |
Q47764617 | Associations between epidermal growth factor receptor mutations and histological subtypes of lung adenocarcinoma according to the IASLC/ATS/ERS classification in Chinese patients |
Q36337437 | Associations between mutations and histologic patterns of mucin in lung adenocarcinoma: invasive mucinous pattern and extracellular mucin are associated with KRAS mutation |
Q43265336 | Attacking cancer at its foundation |
Q58804389 | Autochthonous murine models for the study of smoker and never-smoker associated lung cancers |
Q35583019 | Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers |
Q38960732 | Automated objective determination of percentage of malignant nuclei for mutation testing |
Q35014385 | Awakening guardian angels: drugging the p53 pathway |
Q37738168 | B-RAF inhibitors: an evolving role in the therapy of malignant melanoma. |
Q104475963 | BEBT-109, a pan-mutant-selective EGFR inhibitor with potent antitumor activity in EGFR-mutant non-small cell lung cancer |
Q37841599 | BIBW 2992 in non-small cell lung cancer |
Q24649935 | BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models |
Q37708873 | BIM deletion polymorphisms in Hispanic patients with non-small cell lung cancer carriers of EGFR mutations |
Q35588268 | BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. |
Q28756824 | BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations |
Q36413639 | BRAF mutation testing with a rapid, fully integrated molecular diagnostics system |
Q42733647 | BRAF targeted therapy changes the treatment paradigm in melanoma |
Q92284666 | Barcode sequencing identifies resistant mechanisms to epidermal growth factor receptor inhibitors in circulating tumor DNA of lung cancer patients |
Q64913573 | Basic science of lung cancer. |
Q33218734 | Basics of molecular diagnostics and therapy of malignant tumors |
Q50095063 | Basket Studies: Redefining Clinical Trials in the Era of Genome-Driven Oncology. |
Q36011788 | Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology |
Q28740430 | Benchmarking of mutation diagnostics in clinical lung cancer specimens |
Q59808313 | Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors |
Q92218750 | Bevacizumab and CCR2 Inhibitor Nanoparticles Induce Cytotoxicity-Mediated Apoptosis in Doxorubicin-Treated Hepatic and Non-Small Lung Cancer Cells |
Q47142558 | Bevacizumab and gefitinib enhanced whole-brain radiation therapy for brain metastases due to non-small-cell lung cancer |
Q36832129 | Bevacizumab in the treatment of non-small-cell lung cancer |
Q37001902 | Bevacizumab to combat EGFR-TKI resistance in a patient with advanced non-small cell lung cancer harboring an EGFR mutation: A case report |
Q35025931 | Bexarotene plus erlotinib suppress lung carcinogenesis independent of KRAS mutations in two clinical trials and transgenic models |
Q46512789 | Beyond ALK and ROS1: RET, NTRK, EGFR and BRAF gene rearrangements in non-small cell lung cancer |
Q38569159 | Beyond genetics in personalized cancer treatment: assessing dynamics and heterogeneity of tumor responses. |
Q33560928 | Beyond histology: translating tumor genotypes into clinically effective targeted therapies |
Q40340043 | Beyond the TRIBUTE trial: integrating HER1/EGFR tyrosine kinase inhibitors with chemotherapy in advanced NSCLC. |
Q50288609 | Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants |
Q50288599 | Binding of GRB2:SOS1 complex to phosphorylated ligand-responsive EGFR mutants |
Q46963924 | Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients |
Q38386392 | Biobanking for Personalized Medicine |
Q37665845 | Biochemical mechanisms of resistance to small-molecule protein kinase inhibitors |
Q59335693 | Biodegradable Nanoparticles Mediated Co-delivery of Erlotinib (ELTN) and Fedratinib (FDTN) Toward the Treatment of ELTN-Resistant Non-small Cell Lung Cancer (NSCLC) via Suppression of the JAK2/STAT3 Signaling Pathway |
Q35885829 | Bioinformatics and cancer target discovery |
Q81367068 | Biologic staging of non-small-cell lung cancer: prospect or proposal? |
Q37242685 | Biologic therapies for advanced pancreatic cancer |
Q36521850 | Biological agents versus chemotherapy in the treatment of colorectal cancer |
Q36540571 | Biological and clinical implications of EGFR mutations in lung cancer. |
Q45965455 | Biological characteristics and epidermal growth factor receptor tyrosine kinase inhibitors efficacy of EGFR mutation and its subtypes in lung adenocarcinoma. |
Q34094855 | Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO). |
Q34248282 | Biomarker testing for breast, lung, and gastroesophageal cancers at NCI designated cancer centers |
Q34023414 | Biomarkers That Currently Affect Clinical Practice in Lung Cancer: EGFR, ALK, MET, ROS-1, and KRAS |
Q39181810 | Biomarkers and Immunotherapeutic Targets in Glioblastoma |
Q36260477 | Biomarkers and targeted systemic therapies in advanced non-small cell lung cancer |
Q37988924 | Biomarkers and transcriptome profiling of lung cancer |
Q37692666 | Biomarkers in bronchopulmonary cancer |
Q28278305 | Biomarkers in cancer staging, prognosis and treatment selection |
Q37006905 | Biomarkers in drug discovery and development |
Q37371586 | Biomarkers in early cancer drug development: limited utility |
Q34094906 | Biomarkers of acute lung injury: worth their salt? |
Q39569308 | Biomarkers of cancer metastasis through the lymphovascular system: future perspectives |
Q35108419 | Biomarkers of clinical benefit for anti-epidermal growth factor receptor agents in patients with non-small-cell lung cancer |
Q26766535 | Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS |
Q36040606 | Biomarkers that currently affect clinical practice: EGFR, ALK, MET, KRAS |
Q47110241 | Biomarkers/Molecular Targets, Immunotherapy, and Treatments for Non-Small Cell Lung Cancer. |
Q37388387 | Biopsy and mutation detection strategies in non-small cell lung cancer |
Q90697012 | Biopsy on progression in patients with EGFR mutation-positive advanced non-small-cell lung cancer-a Canadian experience |
Q37236777 | BlackOPs: increasing confidence in variant detection through mappability filtering |
Q36842495 | Blood-brain barrier transport of non-viral gene and RNAi therapeutics |
Q36477753 | Body mass index and exon 19 mutation as factors predicting the therapeutic efficacy of gefitinib in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer |
Q35154082 | Bombesin receptor subtype-3 agonists stimulate the growth of lung cancer cells and increase EGF receptor tyrosine phosphorylation |
Q33989444 | Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway |
Q36224108 | Braf and erbB2 mutations correlate with smoking status in lung cancer patients |
Q48569495 | Brain metastases from non-small-cell lung cancer: is there room for improvement? |
Q38233149 | Brain metastases in non-small-cell lung cancer: better outcomes through current therapies and utilization of molecularly targeted approaches |
Q64071943 | Brain metastases in resected non-small cell lung cancer: The impact of different tyrosine kinase inhibitors |
Q41846992 | Brain metastasis effectively treated with erlotinib following the acquisition of resistance to gefitinib: a case report |
Q48044475 | Brain metastasis features and association with tumor epidermal growth factor receptor mutation in patients with adenocarcinoma of the lung |
Q50949344 | Brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma. |
Q37028777 | Broad, Hybrid Capture-Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches |
Q60097206 | Broken genes in solid tumours |
Q41643045 | Bronchioloalveolar neoplasia. |
Q39941747 | Bronchoscopic Re-biopsy for Mutational Analysis of Non-small Cell Lung Cancer |
Q36929987 | Building a personalized medicine infrastructure at a major cancer center |
Q38385958 | Building the foundation for genomics in precision medicine |
Q35176335 | By downregulating Ku80, hsa-miR-526b suppresses non-small cell lung cancer |
Q37421439 | Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer |
Q34031219 | C4.4A as a biomarker in pulmonary adenocarcinoma and squamous cell carcinoma |
Q35962454 | CCR 20th Anniversary Commentary: RAS as a Biomarker for EGFR--Targeted Therapy for Colorectal Cancer-From Concept to Practice |
Q34342934 | CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma |
Q55072491 | CDKN2A(p16) and HRAS are frequently mutated in vulvar squamous cell carcinoma. |
Q54673900 | CHFR hypermethylation and EGFR mutation are mutually exclusive and exhibit contrastive clinical backgrounds and outcomes in non-small cell lung cancer. |
Q35778685 | CI-988 Inhibits EGFR Transactivation and Proliferation Caused by Addition of CCK/Gastrin to Lung Cancer Cells |
Q27310110 | CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis. |
Q46979383 | CNS response after erlotinib therapy in a patient with metastatic NSCLC with an EGFR mutation |
Q38924458 | CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect EGFR and KRAS mutations. |
Q33808203 | CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance. |
Q36525874 | CRISPR/Cas-mediated genome editing to treat EGFR-mutant lung cancer: a personalized molecular surgical therapy |
Q38614582 | CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer |
Q41751613 | CT Radiogenomic Characterization of EGFR, K-RAS, and ALK Mutations in Non-Small Cell Lung Cancer |
Q60301839 | CT Slice Thickness and Convolution Kernel Affect Performance of a Radiomic Model for Predicting EGFR Status in Non-Small Cell Lung Cancer: A Preliminary Study |
Q41997242 | CT characteristics in pulmonary adenocarcinoma with epidermal growth factor receptor mutation |
Q100416116 | CT features and disease spread patterns in ROS1-rearranged lung adenocarcinomas: comparison with those of EGFR-mutant or ALK-rearranged lung adenocarcinomas |
Q89116459 | CT features of HER2-mutant lung adenocarcinomas |
Q35086187 | CT tumor volume measurement in advanced non-small-cell lung cancer: Performance characteristics of an emerging clinical tool |
Q36615733 | CYFRA 21-1 level predicts survival in non-small-cell lung cancer patients receiving gefitinib as third-line therapy |
Q37352553 | CYP2C19 genotype-based phase I studies of a c-Met inhibitor tivantinib in combination with erlotinib, in advanced/metastatic non-small cell lung cancer |
Q61806215 | Can CT radiomic analysis in NSCLC predict histology and EGFR mutation status? |
Q35537522 | Can EGFR mutation status be reliably determined in pre-operative needle biopsies from adenocarcinomas of the lung? |
Q36427587 | Can EGFR-TKIs be used in first line treatment for advanced non-small cell lung cancer based on selection according to clinical factors? - A literature-based meta-analysis |
Q26999304 | Can microRNAs improve the management of lung cancer patients? A clinician's perspective |
Q34986181 | Can systems biology understand pathway activation? Gene expression signatures as surrogate markers for understanding the complexity of pathway activation |
Q53243032 | Cancer Genomics. |
Q35999625 | Cancer Phenotype Diagnosis and Drug Efficacy within Japanese Health Care |
Q37153533 | Cancer as a system failure |
Q37810056 | Cancer biology and genomics: translating discoveries, transforming pathology |
Q36561609 | Cancer biomarkers: a systems approach |
Q42968372 | Cancer biomarkers: closer to delivering on their promise |
Q27010961 | Cancer concepts and principles: primer for the interventional oncologist-part II |
Q34002709 | Cancer driver mutations in protein kinase genes |
Q36111899 | Cancer drug discovery through collaboration. |
Q37399404 | Cancer epigenomics: implications of DNA methylation in personalized cancer therapy |
Q28275089 | Cancer genes and the pathways they control |
Q36481954 | Cancer genes in lung cancer: racial disparities: are there any? |
Q38180646 | Cancer genomics and inherited risk |
Q34301519 | Cancer genomics and pathology: all together now. |
Q63018119 | Cancer genomics: from discovery science to personalized medicine |
Q35583180 | Cancer immunology--analysis of host and tumor factors for personalized medicine |
Q36822291 | Cancer pharmacogenomics |
Q26741009 | Cancer pharmacogenomics, challenges in implementation, and patient-focused perspectives |
Q24289309 | Cancer pharmacogenomics: strategies and challenges |
Q90372559 | Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2 |
Q36359653 | Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations |
Q38028798 | Cancer treatment according to BRCA1 and BRCA2 mutations |
Q44574128 | Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins |
Q44960549 | Cancer: understanding the target |
Q36385644 | Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma |
Q36092823 | Carcinogenesis, cancer therapy and chemoprevention |
Q33249923 | Carcinosarcoma of the colon: report of a case with morphological, ultrastructural and molecular analysis |
Q37061596 | Cardiac toxicity: old and new issues in anti-cancer drugs. |
Q33807542 | Cardio-Oncology: Cancer Therapy-related Cardiovascular Complications in a Molecular Targeted Era: New Concepts and Perspectives |
Q93203400 | Case of Proteinuria, Worsening Hypertension, and Glomerular Endotheliosis With Erlotinib and Gefitinib |
Q53631481 | Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas. |
Q39205831 | Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells. |
Q35219426 | Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms. |
Q38268502 | Catalytic mechanisms and regulation of protein kinases |
Q91805218 | Cell Model Passports-a hub for clinical, genetic and functional datasets of preclinical cancer models |
Q24598357 | Cell signaling by receptor tyrosine kinases |
Q52361534 | Cell signaling heterogeneity is modulated by both cell-intrinsic and -extrinsic mechanisms: An integrated approach to understanding targeted therapy. |
Q41431886 | Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas. |
Q34789161 | Cell-based Models for Discovery of Pharmacogenomic Markers of Anticancer Agent Toxicity. |
Q81939291 | Cell-free DNA resuscitated for tumor testing |
Q38263419 | Cell-free circulating tumor DNA in plasma/serum of non-small cell lung cancer |
Q36003118 | Cellular responses to EGFR inhibitors and their relevance to cancer therapy |
Q38214154 | Ceritinib for treatment of ALK-rearranged advanced non-small-cell lung cancer |
Q36171281 | Cetuximab and biomarkers in non-small-cell lung carcinoma |
Q35023512 | Cetuximab for the treatment of advanced bronchioloalveolar carcinoma (BAC): an Eastern Cooperative Oncology Group phase II study (ECOG 1504). |
Q36668224 | Cetuximab in the treatment of head and neck cancer |
Q46261715 | Cetuximab plus carboplatin and paclitaxel with or without bevacizumab versus carboplatin and paclitaxel with or without bevacizumab in advanced NSCLC (SWOG S0819): a randomised, phase 3 study |
Q41894424 | Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization |
Q36832116 | Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer. |
Q98292342 | Cetuximab-Triptolide Conjugate Suppresses the Growth of EGFR-Overexpressing Lung Cancers through Targeting RNA Polymerase II |
Q44948356 | Cetuximab: an IgG(1) monoclonal antibody for the treatment of epidermal growth factor receptor-expressing tumours |
Q88790405 | Challenges and opportunities of pharmacogenetics in drug development |
Q34608597 | Challenges in Implementing Personalized Medicine for Lung Cancer within a National Healthcare System |
Q37220383 | Challenges in initiating and conducting personalized cancer therapy trials: perspectives from WINTHER, a Worldwide Innovative Network (WIN) Consortium trial |
Q38947180 | Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease |
Q37177604 | Challenges of detecting EGFR T790M in gefitinib/erlotinib-resistant tumours |
Q35179046 | Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease |
Q34225871 | Change or die: targeting adaptive signaling to kinase inhibition in cancer cells |
Q26774513 | Changing strategies for target therapy in gastric cancer |
Q36849676 | Changing the paradigm: the potential for targeted therapy in laryngeal squamous cell carcinoma |
Q34778365 | Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART. |
Q28706226 | Characteristics of lung cancers harboring NRAS mutations |
Q51661151 | Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients. |
Q55317607 | Characterization of Covalent-Reversible EGFR Inhibitors. |
Q36389868 | Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer |
Q58786657 | Characterization of Factors Affecting the Detection Limit of EGFR p.T790M in Circulating Tumor DNA |
Q36248587 | Characterization of a highly effective protein substrate for analysis of JAK2(V617F) Activity |
Q92164128 | Characterization of cancer omics and drug perturbations in panels of lung cancer cells |
Q47139649 | Characterization of the efficacies of osimertinib and nazartinib against cells expressing clinically relevant epidermal growth factor receptor mutations |
Q43056671 | Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas |
Q27317429 | Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling |
Q37004639 | Chasing targets for EGFR tyrosine kinase inhibitors in non-small-cell lung cancer: Asian perspectives |
Q64058283 | Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape |
Q36185641 | Chemoprevention of lung cancer: concepts and strategies |
Q46936682 | Chemopreventive effects of cyclooxygenase-2 inhibitor and epidermal growth factor-receptor kinase inhibitor on rat urinary bladder carcinogenesis |
Q36989648 | Chemoradiation for definitive, preoperative, or postoperative therapy of locally advanced non-small cell lung cancer |
Q37799220 | Chemotherapy and signaling: How can targeted therapies supercharge cytotoxic agents? |
Q37614566 | Chemotherapy for lung cancer: the state of the art in 2009. |
Q40375603 | Chemotherapy for metastatic NSCLC: current status and future direction |
Q38237655 | Chemotherapy in Metastatic NSCLC - New Regimens (Pemetrexed, Nab-Paclitaxel) |
Q38838014 | Chemotherapy remains an essential element of personalized care for persons with lung cancers |
Q30940337 | Chemotherapy versus tyrosine kinase inhibitor in EGFR unselected population advanced non-small cell lung cancer still matter of debate?-An update incorporating the DELTA trial data |
Q82297408 | Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas |
Q35217204 | Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells |
Q39869486 | Chromogenic in situ hybridization analysis of Epidermal Growth Factor Receptor gene/chromosome 7 numerical aberrations in hepatocellular carcinoma based on tissue microarrays |
Q34198721 | Chromogenic in situ hybridization to detect EGFR gene copy number in cell blocks from fine-needle aspirates of non small cell lung carcinomas and lung metastases from colo-rectal cancer |
Q36223578 | Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities |
Q33781119 | Chromosomal and genomic changes in lung cancer |
Q41487356 | Chromosome 7 Multiplication in EGFR-positive Lung Carcinomas Based on Tissue Microarray Analysis |
Q42453112 | Chromosome 7 aneusomy in metaplastic breast carcinomas with chondroid, squamous, and spindle-cell differentiation |
Q35837368 | Chronic Obstructive Pulmonary Disease-Related Non-Small-Cell Lung Cancer Exhibits a Low Prevalence of EGFR and ALK Driver Mutations |
Q37641586 | Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells |
Q36287400 | Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c |
Q52640291 | Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs. |
Q35207885 | Cigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors. |
Q36309536 | Cigarette smoking impairs the response of EGFR-TKIs therapy in lung adenocarcinoma patients by promoting EGFR signaling and epithelial-mesenchymal transition |
Q38232303 | Ciliated muconodular papillary tumor of the lung: a newly defined peripheral pulmonary tumor with conspicuous mucin pool mimicking colloid adenocarcinoma: a case report and review of literature |
Q36834331 | Circulating DNA addresses cancer monitoring in non small cell lung cancer patients for detection and capturing the dynamic changes of the disease |
Q37635310 | Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy |
Q37780014 | Circulating endothelial and endothelial progenitor cells in non-small-cell lung cancer. |
Q33640472 | Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages. |
Q28077340 | Circulating tumor cells versus circulating tumor DNA in lung cancer-which one will win? |
Q37673460 | Circulating tumor cells: a window into cancer biology and metastasis |
Q24631347 | Circulating tumor cells: approaches to isolation and characterization |
Q37000646 | Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients. |
Q39169544 | Cisplatin influences acquisition of resistance to molecular-targeted agents through epithelial-mesenchymal transition-like changes |
Q38043495 | Citation classics: Top 50 cited articles in 'respiratory system'. |
Q38262804 | Class act: safety comparison of approved tyrosine kinase inhibitors for non-small-cell lung carcinoma. |
Q50050455 | Classification and regression tree analysis of patients with non-small-cell lung cancer treated with gefitinib after chemotherapy. |
Q35654703 | Classification of Epidermal Growth Factor Receptor Gene Mutation Status Using Serum Proteomic Profiling Predicts Tumor Response in Patients with Stage IIIB or IV Non-Small-Cell Lung Cancer |
Q38574971 | Classification of different patterns of pulmonary adenocarcinomas. |
Q52888052 | Clinical Characteristics and Continued Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Administration in EGFR-mutated Non-Small Cell Lung Cancer with Skeletal Metastasis. |
Q47168748 | Clinical Implications of the Autophagy Core Gene Variations in Advanced Lung Adenocarcinoma Treated with Gefitinib |
Q36613044 | Clinical Next Generation Sequencing for Precision Medicine in Cancer |
Q57214546 | Clinical Outcomes of EGFR Exon 20 Insertion Mutations in Advanced Non-small Cell Lung Cancer in Korea |
Q36238822 | Clinical Significance of ErbB Receptor Family in Urothelial Carcinoma of the Bladder: A Systematic Review and Meta-Analysis |
Q27853182 | Clinical Translation and Validation of a Predictive Biomarker for Patritumab, an Anti-human Epidermal Growth Factor Receptor 3 (HER3) Monoclonal Antibody, in Patients With Advanced Non-small Cell Lung Cancer |
Q38270195 | Clinical Utility of Circulating Tumor Cells in ALK-Positive Non-Small-Cell Lung Cancer |
Q38519252 | Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6. |
Q43195843 | Clinical activity of the mutant-selective EGFR inhibitor AZD9291 in patients with EGFR inhibitor-resistant non-small cell lung cancer |
Q37455251 | Clinical and Molecular Characteristics of NF1-Mutant Lung Cancer. |
Q29615475 | Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers |
Q64098526 | Clinical and computed tomography characteristics of non-small cell lung cancer with ALK gene rearrangement: Comparison with EGFR mutation and ALK/EGFR-negative lung cancer |
Q38042709 | Clinical and economic review of erlotinib in non-small-cell lung cancer |
Q34952066 | Clinical and epidemiological study of EGFR mutations and EML4-ALK fusion genes among Indian patients with adenocarcinoma of the lung |
Q46815372 | Clinical and molecular predictors of response to EGFR tyrosine kinase inhibitors in non-small cell lung cancer |
Q55003763 | Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor. |
Q40048521 | Clinical application of a cancer genomic profiling assay to guide precision medicine decisions |
Q38402811 | Clinical application of amplicon-based next-generation sequencing to therapeutic decision making in lung cancer |
Q38065062 | Clinical applications for microRNAs in cancer |
Q36111249 | Clinical applications for targeted therapy in bladder cancer |
Q36311991 | Clinical applications of genomics in head and neck cancer |
Q38504491 | Clinical approaches to treat patients with non-small cell lung cancer and epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance. |
Q36628704 | Clinical aspects of epidermal growth factor receptor inhibitors: benefit and risk |
Q46446185 | Clinical benefit in NSCLC: advanced-stage patients require symptom-improving palliation. Experiences from the 'Iressa' expanded access program |
Q33279462 | Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer. |
Q37523898 | Clinical biomarkers in oncology: focus on colorectal cancer |
Q37815145 | Clinical cancer genomics: how soon is now? |
Q38253280 | Clinical cancer research: the past, present and the future |
Q34610381 | Clinical characteristics and course of 63 patients with BRAF mutant lung cancers |
Q41920066 | Clinical characteristics of brain metastases from lung cancer according to histological type: Pretreatment evaluation and survival following whole-brain radiotherapy |
Q54109548 | Clinical characteristics of non-small cell lung cancer harboring mutations in exon 20 of EGFR or HER2. |
Q35023498 | Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations |
Q42780600 | Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer |
Q36031642 | Clinical development of gefitinib in non-small-cell lung cancer and the Iressa Survival Evaluation in Lung Cancer trial |
Q35566234 | Clinical development of phosphatidylinositol-3 kinase pathway inhibitors |
Q64055605 | Clinical development of targeted and immune based anti-cancer therapies |
Q44634377 | Clinical development of targeted moledular cancer drugs |
Q33742964 | Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines |
Q46552225 | Clinical effects for patients with recurrent advanced non-small cell lung cancer treated with icotinib hydrochloride |
Q49720695 | Clinical efficacy and safety of afatinib in the treatment of non-small-cell lung cancer in Chinese patients. |
Q90353311 | Clinical evaluation of dacomitinib for the treatment of metastatic non-small cell lung cancer (NSCLC): current perspectives |
Q48422999 | Clinical factors affecting acquired resistance to gefitinib in previously treated Japanese patients with advanced nonsmall cell lung cancer. |
Q35681021 | Clinical features and mutation status of EGFR, KRAS, BRAF, EML4-ALK and ROS1 between surgical resection samples and non surgical resection samples in lung cancer |
Q29615472 | Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK |
Q33779181 | Clinical features and treatment outcome of non-small cell lung cancer (NSCLC) patients with uncommon or complex epidermal growth factor receptor (EGFR) mutations |
Q37220488 | Clinical features reflect exon sites of EGFR mutations in patients with resected non-small-cell lung cancer |
Q53303546 | Clinical impact of amphiregulin expression in patients with epidermal growth factor receptor (EGFR) wild-type nonsmall cell lung cancer treated with EGFR-tyrosine kinase inhibitors. |
Q37317171 | Clinical impact of high-throughput gene expression studies in lung cancer |
Q38270567 | Clinical impact of the new IASLC/ATS/ERS lung adenocarcinoma classification for chest surgeons |
Q26823978 | Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges |
Q27851527 | Clinical implications of KRAS mutations in lung cancer patients treated with tyrosine kinase inhibitors: an important role for mutations in minor clones |
Q37581276 | Clinical implications of genetic heterogeneity in multifocal pulmonary adenocarcinomas |
Q36519876 | Clinical implications of genetic polymorphisms on stomach cancer drug therapy |
Q34267563 | Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma |
Q34488700 | Clinical implications of the cancer genome |
Q36565941 | Clinical implications of the mechanism of epidermal growth factor receptor inhibitors |
Q91596373 | Clinical importance of long non‑coding RNA LINC00460 expression in EGFR‑mutant lung adenocarcinoma |
Q27024235 | Clinical investigation of receptor and non-receptor tyrosine kinase inhibitors for the treatment of epithelial ovarian cancer |
Q47548020 | Clinical management and outcome of patients with advanced NSCLC carrying EGFR mutations in Spain |
Q49930825 | Clinical mutational profiling of 1006 lung cancers by next generation sequencing. |
Q50629732 | Clinical mutational profiling of bone metastases of lung and colon carcinoma and malignant melanoma using next-generation sequencing. |
Q54313342 | Clinical next-generation sequencing in patients with non-small cell lung cancer. |
Q31158651 | Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations |
Q54118554 | Clinical outcome study of crizotinib in immunohistochemistry-proven echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion gene among Indian patients with adenocarcinoma lung. |
Q37750786 | Clinical outcomes in non-small-cell lung cancer in relation to expression of predictive and prognostic biomarkers |
Q37334996 | Clinical outcomes in non-small-cell lung cancer patients with EGFR mutations: pooled analysis |
Q39457284 | Clinical outcomes in patients with advanced EGFR-mutated non-small cell lung cancer in South Western Sydney Local Health District. |
Q36715107 | Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21. |
Q43272211 | Clinical outcomes of advanced non-small cell lung cancer patients screened for epidermal growth factor receptor gene mutations |
Q38019974 | Clinical outcomes with erlotinib in patients with epidermal growth factor receptor mutation. |
Q34029615 | Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing |
Q37873453 | Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on 4-anilinoquinazolines. |
Q36316009 | Clinical potential of gene mutations in lung cancer |
Q36212891 | Clinical potential of inhibitors of survival pathways and activators of apoptotic pathways in treatment of cervical cancer: changing the apoptotic balance. |
Q36345960 | Clinical relevance of ion channels for diagnosis and therapy of cancer |
Q34500155 | Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis |
Q33873653 | Clinical sequencing using a next-generation sequencing-based multiplex gene assay in patients with advanced solid tumors. |
Q34041761 | Clinical significance of BIM deletion polymorphism in non-small-cell lung cancer with epidermal growth factor receptor mutation |
Q47118266 | Clinical significance of cripto-1 expression in lung adenocarcinoma |
Q34582813 | Clinical significance of gefitinib antitumor activity in patients with lung adenocarcinoma |
Q42745155 | Clinical significance of pretreatment C-reactive protein in patients with advanced nonsquamous, non-small cell lung cancer who received gefitinib |
Q46351405 | Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer |
Q90403153 | Clinical significance of repeat rebiopsy in detecting the EGFR T790M secondary mutation in patients with non-small cell lung cancer |
Q84584265 | Clinical significance of serum hepatocyte growth factor and epidermal growth factor gene somatic mutations in patients with non-squamous non-small cell lung cancer receiving gefitinib or erlotinib |
Q38041563 | Clinical testing for molecular targets for personalized treatment in lung cancer. |
Q31128049 | Clinical translation of genotyping and haplotyping data: implementation of in vivo pharmacology experience leading drug prescription to pharmacotyping |
Q37196395 | Clinical trials of novel and targeted therapies: endpoints, trial design, and analysis |
Q24630466 | Clinical use of crizotinib for the treatment of non-small cell lung cancer |
Q47704888 | Clinical usefulness of KRAS, BRAF, and PIK3CA mutations as predictive markers of cetuximab efficacy in irinotecan- and oxaliplatin-refractory Japanese patients with metastatic colorectal cancer |
Q35180028 | Clinical usefulness of gefitinib for non-small-cell lung cancer with a double epidermal growth factor receptor mutation |
Q92025240 | Clinical utility of SMARCA4 testing by immunohistochemistry in rare ovarian tumours |
Q34011705 | Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidence |
Q35107524 | Clinical validation of a PCR assay for the detection of EGFR mutations in non-small-cell lung cancer: retrospective testing of specimens from the EURTAC trial. |
Q33633606 | Clinical value of the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification of lung adenocarcinoma |
Q37539427 | Clinical-molecular factors predicting response and survival for tyrosine-kinase inhibitors. |
Q38077041 | Clinically relevant cancer biomarkers and pharmacogenetic assays |
Q80100938 | Clinico-pathological and biological significance of tyrosine kinase domain gene mutations and overexpression of epidermal growth factor receptor for lung adenocarcinoma |
Q37693426 | Clinicopathologic characteristics and outcomes of Chinese patients with non-small-cell lung cancer and BRAF mutation |
Q35790161 | Clinicopathologic characteristics of patients with ROS1 fusion gene in non-small cell lung cancer: a meta-analysis |
Q35007886 | Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium |
Q54980290 | Clinicopathological Characteristics and Mutations Driving Development of Early Lung Adenocarcinoma: Tumor Initiation and Progression. |
Q90217220 | Clinicopathological and Prognostic Significance of EML4-ALK Rearrangement in Patients with Surgically Resected Lung Adenocarcinoma: A Propensity Score Matching Study |
Q31167585 | Clinicopathological and demographical characteristics of non-small cell lung cancer patients with ALK rearrangements: a systematic review and meta-analysis |
Q33633715 | Clinicopathological and prognostic features of surgically resected pathological stage I lung adenocarcinoma harboring epidermal growth factor receptor and K-ras mutation |
Q50738801 | Clinicopathological and prognostic significances of EGFR, KRAS and BRAF mutations in biliary tract carcinomas in Taiwan. |
Q54269790 | Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung. |
Q34169194 | Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer |
Q64234032 | Clinicopathological features and clinical efficacy of crizotinib in Chinese patients with -positive non-small cell lung cancer |
Q83568242 | Clinicopathological features of lung adenocarcinoma with KRAS mutations |
Q55259571 | Clinicopathological features of younger (aged ≤ 50 years) lung adenocarcinoma patients harboring the EML4-ALK fusion gene. |
Q51607504 | Clinicopathological predictors of EGFR/KRAS mutational status in primary lung adenocarcinomas. |
Q38784576 | Clinicopathological significance of p14ARF expression in lung cancer: a meta-analysis |
Q27027655 | Clonal evolution in hematological malignancies and therapeutic implications |
Q91272209 | Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers |
Q34254343 | Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas |
Q40343596 | Co-active receptor tyrosine kinases mitigate the effect of FGFR inhibitors in FGFR1-amplified lung cancers with low FGFR1 protein expression. |
Q45210729 | Co-expression of receptors of the HER family correlates with clinical outcome in non-small cell lung cancer (NSCLC). |
Q92578527 | Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy |
Q42200131 | Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance |
Q33682941 | Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5125 Chinese cohorts |
Q34658204 | Coexistence of KRAS mutation with mutant but not wild-type EGFR predicts response to tyrosine-kinase inhibitors in human lung cancer. |
Q36671123 | Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling |
Q33206782 | Coexpression of epidermal growth factor receptor with related factors is associated with a poor prognosis in non-small-cell lung cancer |
Q27691448 | Collaborative Care in NSCLC; the Role of Early Palliative Care |
Q27853014 | Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab |
Q37679938 | Colorectal cancer in review: the role of the EGFR pathway |
Q26824877 | Combating acquired resistance to tyrosine kinase inhibitors in lung cancer |
Q38812090 | Combating trastuzumab resistance by targeting thioredoxin-1/PTEN interaction |
Q52588501 | Combination TS-1 plus EGFR-tyrosine kinase inhibitors (TKIs) for the treatment of non-small cell lung cancer after progression on first-line or further EGFR-TKIs: A phase II, single-arm trial. |
Q35043675 | Combination of EGFR-TKIs and chemotherapy as first-line therapy for advanced NSCLC: a meta-analysis |
Q53681935 | Combination of Pyrosequencing® and Sanger sequencing reveals alleged novel mutation in exon 18 of EGFR. |
Q64111464 | Combination of cetuximab with met inhibitor in control of cetuximab-resistant oral squamous cell carcinoma |
Q48352757 | Combination of chemotherapy and gefitinib as first-line treatment for patients with advanced lung adenocarcinoma and sensitive EGFR mutations: A randomized controlled trial. |
Q34318204 | Combination of phosphorylated and truncated EGFR correlates with higher tumor and nodal stage in head and neck cancer |
Q36795322 | Combination of radiotherapy with EGFR antagonists for head and neck carcinoma |
Q38245873 | Combination of stereotactic ablative body radiation with targeted therapies |
Q92530282 | Combination therapy of brain radiotherapy and EGFR-TKIs is more effective than TKIs alone for EGFR-mutant lung adenocarcinoma patients with asymptomatic brain metastasis |
Q39118597 | Combination therapy with anti-ErbB3 monoclonal antibodies and EGFR TKIs potently inhibits non-small cell lung cancer |
Q33658626 | Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicity |
Q36143394 | Combinatorial biomarkers: From early toxicology assays to patient population profiling |
Q24632064 | Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations |
Q39009280 | Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells |
Q41811594 | Combined EGFR/MET or EGFR/HSP90 inhibition is effective in the treatment of lung cancers codriven by mutant EGFR containing T790M and MET. |
Q39310312 | Combined Erlotinib and Cetuximab overcome the acquired resistance to epidermal growth factor receptors tyrosine kinase inhibitor in non-small-cell lung cancer |
Q35836350 | Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis |
Q39051337 | Combined Tumor Suppressor Defects Characterize Clinically Defined Aggressive Variant Prostate Cancers |
Q34345154 | Combined action of the dinuclear platinum compound BBR3610 with the PI3-K inhibitor PX-866 in glioblastoma |
Q37111832 | Combined anti-proliferative and anti-angiogenic strategies for cancer |
Q37080964 | Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients |
Q54977986 | Combined caveolin-1 and epidermal growth factor receptor expression as a prognostic marker for breast cancer. |
Q33881706 | Combined effects of asbestos and cigarette smoke on the development of lung adenocarcinoma: different carcinogens may cause different genomic changes |
Q57736167 | Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer |
Q36230865 | Combined inhibition of insulin-like growth factor-1 receptor enhances the effects of gefitinib in a human non-small cell lung cancer resistant cell line |
Q37522017 | Combined therapies for cancer: a review of EGFR-targeted monotherapy and combination treatment with other drugs |
Q40167169 | Combined treatment of bladder cancer cell lines with lapatinib and varying chemotherapy regimens--evidence of schedule-dependent synergy |
Q39559565 | Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway |
Q39850353 | Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance |
Q91816037 | Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets |
Q34104025 | Combining AKT inhibition with chloroquine and gefitinib prevents compensatory autophagy and induces cell death in EGFR mutated NSCLC cells |
Q34206363 | Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma |
Q41635081 | Combining PET/CT with serum tumor markers to improve the evaluation of histological type of suspicious lung cancers |
Q41892153 | Combining chemotherapy with epidermal growth factor receptor inhibition in advanced non-small cell lung cancer. |
Q34066159 | Combining erlotinib and cetuximab is associated with activity in patients with non-small cell lung cancer (including squamous cell carcinomas) and wild-type EGFR or resistant mutations |
Q57279749 | Combining genomic analyses with tumour-derived slice cultures for the characterization of an EGFR-activating kinase mutation in a case of glioblastoma |
Q26852202 | Combining targeted agents and hypo- and hyper-fractionated radiotherapy in NSCLC |
Q38868047 | Combining three antibodies nullifies feedback-mediated resistance to erlotinib in lung cancer |
Q50056486 | Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis. |
Q38335360 | Common EGFR-mutated subgroups (Del19/L858R) in advanced non-small-cell lung cancer: chasing better outcomes with tyrosine kinase inhibitors |
Q57274907 | Common and Contrasting Genomic Profiles among the Major Human Lung Cancer Subtypes |
Q34906960 | Common and rare EGFR and KRAS mutations in a Dutch non-small-cell lung cancer population and their clinical outcome. |
Q35041632 | Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin |
Q42346456 | Comparable rate of EGFR kinase domain mutation in lung adenocarcinomas from Chinese male and female never-smokers |
Q92662253 | Comparative Analysis of Two Methods for the Detection of EGFR Mutations in Plasma Circulating Tumor DNA from Lung Adenocarcinoma Patients |
Q60046465 | Comparative Transcriptomics Unravels Prodigiosin's Potential Cancer-Specific Activity Between Human Small Airway Epithelial Cells and Lung Adenocarcinoma Cells |
Q45770152 | Comparative analyses of overall survival in patients with anaplastic lymphoma kinase-positive and matched wild-type advanced nonsmall cell lung cancer |
Q24541311 | Comparative analysis of cancer genes in the human and chimpanzee genomes |
Q51667874 | Comparative analysis of clinicoradiologic characteristics of lung adenocarcinomas with ALK rearrangements or EGFR mutations. |
Q44219909 | Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall cell lung cancer |
Q33927591 | Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance |
Q36519015 | Comparative and integrative functional genomics of HCC. |
Q36358798 | Comparative pharmacogenomics of antiretroviral and cytotoxic treatments. |
Q35790108 | Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues |
Q34560075 | Comparing antibody and small-molecule therapies for cancer |
Q60922980 | Comparison of Clinicopathological Features and Prognosis between Rearrangements and Mutations in Surgically Resected Early-stage Lung Adenocarcinoma |
Q36660393 | Comparison of Direct Sequencing, PNA Clamping-Real Time Polymerase Chain Reaction, and Pyrosequencing Methods for the Detection of EGFR Mutations in Non-small Cell Lung Carcinoma and the Correlation with Clinical Responses to EGFR Tyrosine Kinase In |
Q36882732 | Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC. |
Q89666748 | Comparison of EML4-ALK fusion gene positive rate in different detection methods and samples of non-small cell lung cancer |
Q36148697 | Comparison of Epidermal Growth Factor Receptor Mutations between Metastatic Lymph Node Diagnosed by EBUS-TBNA and Primary Tumor in Non-Small Cell Lung Cancer |
Q34947842 | Comparison of IHC, FISH and RT-PCR methods for detection of ALK rearrangements in 312 non-small cell lung cancer patients in Taiwan |
Q34756451 | Comparison of KRAS and EGFR gene status between primary non-small cell lung cancer and local lymph node metastases: implications for clinical practice |
Q40368173 | Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations |
Q49593937 | Comparison of Thoracic Radiotherapy Efficacy Between Patients With and Without EGFR-mutated Lung Adenocarcinoma. |
Q85776063 | Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer: a retrospective analysis |
Q47162466 | Comparison of cross-platform technologies for EGFR T790M testing in patients with non-small cell lung cancer |
Q36474664 | Comparison of different methods for detecting epidermal growth factor receptor mutations in peripheral blood and tumor tissue of non-small cell lung cancer as a predictor of response to gefitinib |
Q41709088 | Comparison of direct sequencing and amplification refractory mutation system for detecting epidermal growth factor receptor mutation in non-small-cell lung cancer patients: a systematic review and meta-analysis |
Q54300832 | Comparison of epidermal growth factor receptor mutation statuses in tissue and plasma in stage I-IV non-small cell lung cancer patients. |
Q46195110 | Comparison of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in tyrosine kinase inhibitor-naive non-small-cell lung cancer |
Q30438089 | Comparison of global versus epidermal growth factor receptor pathway profiling for prediction of lapatinib sensitivity in bladder cancer |
Q89585374 | Comparison of next-generation sequencing and immunohistochemistry analysis for targeted therapy-related genomic status in lung cancer patients |
Q37708814 | Comparison of outcomes of tyrosine kinase inhibitor in first- or second-line therapy for advanced non-small-cell lung cancer patients with sensitive EGFR mutations |
Q54652248 | Comparison of p53 and epidermal growth factor receptor gene status between primary tumors and lymph node metastases in non-small cell lung cancers. |
Q54117313 | Comparison of plasma ctDNA and tissue/cytology-based techniques for the detection of EGFR mutation status in advanced NSCLC: Spanish data subset from ASSESS. |
Q37644815 | Comparison of small biopsy specimens and surgical specimens for the detection of EGFR mutations and EML4-ALK in non-small-cell lung cancer |
Q94453279 | Comparison of the characteristics of uncommon epidermal growth factor receptor (EGFR) mutations and EGFR-tyrosine kinase inhibitor treatment in patients with non-small cell lung cancer from different ethnic groups |
Q54941379 | Comparison of the effects of the three major tyrosine kinase inhibitors as first-line therapy for non-small-cell lung cancer harboring epidermal growth factor receptor mutations. |
Q38091669 | Comparison of the efficacy and safety of single-agent erlotinib and doublet molecular targeted agents based on erlotinib in advanced non-small cell lung cancer (NSCLC): a systematic review and meta-analysis |
Q37204325 | Comparison of the efficacy of icotinib in patients with non-small-cell lung cancer according to the type of epidermal growth factor receptor mutation |
Q40344659 | Comparison of the epidermal growth factor receptor gene and protein in primary non-small-cell-lung cancer and metastatic sites: implications for treatment with EGFR-inhibitors |
Q35541933 | Comparison of uncommon EGFR exon 21 L858R compound mutations with single mutation. |
Q40891431 | Comparisons of the clinicopathological features and survival outcomes between lung cancer patients with adenocarcinoma and squamous cell carcinoma. |
Q36865316 | Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS |
Q39378163 | Competitive allele specific TaqMan PCR for KRAS, BRAF and EGFR mutation detection in clinical formalin fixed paraffin embedded samples. |
Q39477372 | Competitive amplification of differentially melting amplicons (CADMA) enables sensitive and direct detection of all mutation types by high-resolution melting analysis. |
Q33723528 | Complete response in gallbladder cancer to erlotinib plus gemcitabine does not require mutation of the epidermal growth factor receptor gene: a case report |
Q42920934 | Complex Mutations in the Epidermal Growth Factor Receptor Gene in Non-small Cell Lung Cancer |
Q34359601 | Complex mutations & subpopulations of deletions at exon 19 of EGFR in NSCLC revealed by next generation sequencing: potential clinical implications. |
Q93051199 | Compound 15c, a Novel Dual Inhibitor of EGFRL858R/T790M and FGFR1, Efficiently Overcomes Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance of Non-Small-Cell Lung Cancers |
Q36491122 | Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors. |
Q94564084 | Comprehensive Genomic Profiling of Rare Tumors: Routes to Targeted Therapies |
Q35712214 | Comprehensive Molecular Analysis of NSCLC; Clinicopathological Associations |
Q92968477 | Comprehensive analysis of EGFR T790M detection by ddPCR and ARMS-PCR and the effect of mutant abundance on the efficacy of osimertinib in NSCLC patients |
Q64075323 | Comprehensive analysis of age-related somatic mutation profiles in Chinese young lung adenocarcinoma patients |
Q28606437 | Comprehensive assessment of cancer missense mutation clustering in protein structures |
Q36608839 | Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers |
Q30235944 | Comprehensive evaluation of published gene expression prognostic signatures for biomarker-based lung cancer clinical studies |
Q28274701 | Comprehensive genomic characterization of squamous cell lung cancers |
Q36544077 | Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients |
Q39449489 | Comprehensive molecular oncogenomic profiling and miRNA analysis of prostate cancer |
Q42587971 | Comprehensive molecular tumor profiling in radiation oncology: How it could be used for precision medicine |
Q37580410 | Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology |
Q37671783 | Comprehensive profiling of EGFR/HER receptors for personalized treatment of gynecologic cancers |
Q39293400 | Comprehensive study of mutational and clinicopathologic characteristics of adenocarcinoma with lepidic pattern in surgical resected lung adenocarcinoma |
Q30581942 | Computational delineation of tyrosyl-substrate recognition and catalytic landscapes by the epidermal growth factor receptor tyrosine kinase domain |
Q30374663 | Computational modeling of structurally conserved cancer mutations in the RET and MET kinases: the impact on protein structure, dynamics, and stability. |
Q90541036 | Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions |
Q47308660 | Computer-Aided Nodule Assessment and Risk Yield (CANARY) may facilitate non-invasive prediction of EGFR mutation status in lung adenocarcinomas |
Q43059180 | Con: the case for expanded lung cancer research support |
Q36418752 | Concomitance of P-gp/LRP Expression with EGFR Mutations in Exons 19 and 21 in Non-Small Cell Lung Cancers |
Q99582766 | Concomitant genetic alterations are associated with response to EGFR targeted therapy in patients with lung adenocarcinoma |
Q37175551 | Concordant and Discordant EGFR Mutations in Patients With Multifocal Adenocarcinomas: Implications for EGFR-Targeted Therapy |
Q64092527 | Concurrent Driver Gene Mutations as Negative Predictive Factors in Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer |
Q36151764 | Concurrent oncogene mutation profile in Chinese patients with stage Ib lung adenocarcinoma |
Q36546095 | Concurrent radiotherapy with gefitinib in elderly patients with esophageal squamous cell carcinoma: Preliminary results of a phase II study |
Q90074730 | Conformational Insight on WT- and Mutated-EGFR Receptor Activation and Inhibition by Epigallocatechin-3-Gallate: Over a Rational Basis for the Design of Selective Non-Small-Cell Lung Anticancer Agents |
Q50036265 | Considerations About the Use of Biomarkers in Cancer Clinical Trials. |
Q64256027 | Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma |
Q35832237 | Constitutive asymmetric dimerization drives oncogenic activation of epidermal growth factor receptor carboxyl-terminal deletion mutants |
Q37707704 | Construction of a novel cell-based assay for the evaluation of anti-EGFR drug efficacy against EGFR mutation |
Q47107157 | Continuation of gefitinib plus chemotherapy prolongs progression-free survival in advanced non-small cell lung cancer patients who get acquired resistance to gefitinib without T790M mutations |
Q40670339 | Continuous epidermal growth factor receptor-tyrosine kinase inhibitor administration in primary lung adenocarcinoma patients harboring favorable mutations with controlled target lung tumors dose not hinder survival benefit despite small new lesions. |
Q96126112 | Contrast-enhanced T1-weighted image radiomics of brain metastases may predict EGFR mutation status in primary lung cancer |
Q28547357 | Contribution of EGFR and ErbB-3 Heterodimerization to the EGFR Mutation-Induced Gefitinib- and Erlotinib-Resistance in Non-Small-Cell Lung Carcinoma Treatments |
Q52983736 | Contribution of ¹⁸Fluorodeoxyglucose positron emission tomography uptake and TTF-1 expression in the evaluation of the EGFR mutation in patients with lung adenocarcinoma. |
Q37109227 | Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. |
Q35605425 | Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer |
Q64098514 | Conventional transbronchial needle aspiration is promising for identifying EGFR mutations in lung adenocarcinoma |
Q35772768 | Cooperative Hedgehog-EGFR signaling |
Q34489386 | Cooperative, nanoparticle-enabled thermal therapy of breast cancer |
Q36486421 | Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumors |
Q33704537 | Correlation between (18)f-fluorodeoxyglucose uptake and epidermal growth factor receptor mutations in advanced lung cancer |
Q33857652 | Correlation between EGFR mutation status and response to first-line platinum-based chemotherapy in patients with advanced non-small cell lung cancer |
Q39652063 | Correlation between epidermal growth factor receptor-specific nanobody uptake and tumor burden: a tool for noninvasive monitoring of tumor response to therapy |
Q47935277 | Correlation between status of epidermal growth factor receptor mutation and distant metastases of lung adenocarcinoma upon initial diagnosis based on 1063 patients in China |
Q34732930 | Correlation of EGFR mutation and histological subtype according to the IASLC/ATS/ERS classification of lung adenocarcinoma. |
Q46171346 | Correlation of F-18 fluorodeoxyglucose-positron emission tomography maximal standardized uptake value and EGFR mutations in advanced lung adenocarcinoma. |
Q64252788 | Correlation of Thyroid Transcription Factor-1 Expression with Mutations in Non-Small-Cell Lung Cancer: A Meta-Analysis |
Q39669033 | Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma |
Q54477690 | Correlation of immunohistochemical staining p63 and TTF-1 with EGFR and K-ras mutational spectrum and diagnostic reproducibility in non small cell lung carcinoma. |
Q33792597 | Correlation of survival and EGFR mutation with predominant histologic subtype according to the new lung adenocarcinoma classification in stage IB patients |
Q36207143 | Correlations Between the EGFR Mutation Status and Clinicopathological Features of Clinical Stage I Lung Adenocarcinoma. |
Q92408657 | Correlations Study Between 18F-FDG PET/CT Metabolic Parameters Predicting Epidermal Growth Factor Receptor Mutation Status and Prognosis in Lung Adenocarcinoma |
Q33290653 | Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients |
Q36389901 | Correlative studies in neuro-oncology trials: should they influence treatment? |
Q40575534 | Cost-effectiveness analysis of EGFR mutation testing in patients with non-small cell lung cancer (NSCLC) with gefitinib or carboplatin-paclitaxel |
Q90198180 | Cost-effectiveness analysis of the first-line EGFR-TKIs in patients with non-small cell lung cancer harbouring EGFR mutations |
Q34410131 | Coupled mutation finder: a new entropy-based method quantifying phylogenetic noise for the detection of compensatory mutations |
Q38766833 | Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles |
Q48510829 | Creating incentives for genomic research to improve targeting of therapies. |
Q36405628 | Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: a success story to usher in the second decade of molecular targeted therapy in oncology |
Q26738381 | Crizotinib resistance: implications for therapeutic strategies |
Q53148505 | Crizotinib-induced toxicity in an experimental rat model. |
Q37982440 | Crizotinib: a drug that crystallizes a unique molecular subset of non-small-cell lung cancer |
Q35596686 | Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond |
Q33703063 | Cross-Platform Comparison of Four Leading Technologies for Detecting EGFR Mutations in Circulating Tumor DNA from Non-Small Cell Lung Carcinoma Patient Plasma |
Q37335142 | Cross-talk between the ErbB/HER family and the type I insulin-like growth factor receptor signaling pathway in breast cancer |
Q36429474 | Crossing the rubicon in lung adenocarcinoma: the conundrum of EGFR tyrosine kinase mutations |
Q37314768 | Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice |
Q36365503 | Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition |
Q90056608 | Cucurbitacin D Overcomes Gefitinib Resistance by Blocking EGF Binding to EGFR and Inducing Cell Death in NSCLCs |
Q34000044 | Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy |
Q26774502 | Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence |
Q40076524 | Current Japanese regulatory situations of pharmacogenomics in drug administration |
Q46034707 | Current Landscape of Targeted Therapy in Lung Cancer. |
Q88566793 | Current Opportunities and Future Vision of Precision Medicine in Radiation Oncology |
Q64890663 | Current Status of Raf Kinase Inhibitor Protein (RKIP) in Lung Cancer: Behind RTK Signaling. |
Q39016850 | Current Trends in Multidrug Optimization |
Q38543780 | Current and future molecular diagnostics in non-small-cell lung cancer. |
Q37184167 | Current aspects of targeted therapy in head and neck tumors |
Q37723328 | Current challenges for the early clinical development of anticancer drugs in the era of molecularly targeted agents |
Q38172914 | Current clinical application of genomic and proteomic profiling in non-small-cell lung cancer |
Q34310062 | Current concepts on the molecular pathology of non-small cell lung carcinoma |
Q35583920 | Current management of gallbladder carcinoma |
Q52715754 | Current outcomes of postrecurrence survival in patients after resection of non-small cell lung cancer. |
Q36849663 | Current practices and guidelines for clinical next-generation sequencing oncology testing |
Q36832121 | Current role of antibody therapy in patients with metastatic colorectal cancer. |
Q36452704 | Current status and perspective of angiogenesis and antivascular therapeutic strategy: non-small cell lung cancer |
Q36364973 | Current status of cetuximab for the treatment of patients with solid tumors. |
Q35667739 | Current status of immunotherapy for the treatment of lung cancer. |
Q39298725 | Current status of research and treatment for non-small cell lung cancer in never-smoking females |
Q37790985 | Current status of vandetanib (ZD6474) in the treatment of non-small cell lung cancer |
Q43196880 | Current tumor pathology. Clinical expectations of pathological diagnosis |
Q34276419 | Customized chemotherapy based on epidermal growth factor receptor mutation status for elderly patients with advanced non-small-cell lung cancer: a phase II trial. |
Q33438894 | Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression |
Q35146940 | Customizing systemic therapy in patients with advanced non-small cell lung cancer |
Q37043766 | Cutaneous metastasis as an initial presentation of lung adenocarcinoma with KRAS mutation: a case report and literature review |
Q34684234 | Cyclic AMP response element-binding protein overexpression: a feature associated with negative prognosis in never smokers with non-small cell lung cancer |
Q33932736 | Cyclooxygenase-2 inhibitors for non-small-cell lung cancer: A phase II trial and literature review |
Q34637939 | Cyclooxygenase-2 transactivates the epidermal growth factor receptor through specific E-prostanoid receptors and tumor necrosis factor-alpha converting enzyme |
Q24303022 | Cytohesins are cytoplasmic ErbB receptor activators |
Q52031018 | Cytokeratin 20 expression identifies a subtype of pancreatic adenocarcinoma with decreased overall survival. |
Q39673657 | Cytokines and Growth Factors Stimulate Hyaluronan Production: Role of Hyaluronan in Epithelial to Mesenchymal-Like Transition in Non-Small Cell Lung Cancer |
Q37890996 | Cytomorphologic features of advanced lung adenocarcinomas tested for EGFR and KRAS mutations: a retrospective review of 50 cases |
Q80142942 | Cytomorphological correlates of epidermal growth factor receptor mutations in lung carcinoma |
Q91756360 | Cytoplasmic ERβ1 expression is associated with survival of patients with Stage IV lung adenocarcinoma and an EGFR mutation at exon 21 L858R subsequent to treatment with EGFR-TKIs |
Q54356882 | Cytoplasmic YAP expression is associated with prolonged survival in patients with lung adenocarcinomas and epidermal growth factor receptor tyrosine kinase inhibitor treatment. |
Q50920187 | Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association. |
Q38768617 | Cytotoxicity of Salvia miltiorrhiza Against Multidrug-Resistant Cancer Cells. |
Q55028849 | Cytotoxicity of allitinib, an irreversible anti-EGFR agent, in a large panel of human cancer-derived cell lines: KRAS mutation status as a predictive biomarker. |
Q36099324 | DDR2 polymorphisms and mRNA expression in lung cancers of Japanese patients |
Q35364690 | DDX3X induces primary EGFR-TKI resistance based on intratumor heterogeneity in lung cancer cells harboring EGFR-activating mutations |
Q37572189 | DDX59 promotes DNA replication in lung adenocarcinoma |
Q36471888 | DNA Methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer. |
Q53725947 | DNA Mutations May Not Be the Cause of Cancer. |
Q35238487 | DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers |
Q42755164 | DNA repair gene polymorphisms and benefit from gefitinib in never-smokers with lung adenocarcinoma |
Q35892040 | DNA-microarray analysis of brain cancer: molecular classification for therapy |
Q35047411 | DOK2 inhibits EGFR-mutated lung adenocarcinoma |
Q54981550 | Dabrafenib in combination with trametinib in the treatment of patients with BRAF V600-positive advanced or metastatic non-small cell lung cancer: clinical evidence and experience. |
Q45219658 | Dacomitinib as first-line treatment in patients with clinically or molecularly selected advanced non-small-cell lung cancer: a multicentre, open-label, phase 2 trial |
Q26778318 | Dacomitinib in lung cancer: a "lost generation" EGFR tyrosine-kinase inhibitor from a bygone era? |
Q38273671 | Dacomitinib versus erlotinib in patients with advanced-stage, previously treated non-small-cell lung cancer (ARCHER 1009): a randomised, double-blind, phase 3 trial. |
Q47257690 | Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial |
Q42355259 | Dacomitinib, an emerging HER-targeted therapy for non-small cell lung cancer |
Q46228962 | Database of somatic mutations in EGFR with analyses revealing indel hotspots but no smoking-associated signature |
Q93545733 | De la recherche de pointe au patient : un aller-retour? |
Q38651333 | Deciphering mechanisms of acquired T790M mutation after EGFR inhibitors for NSCLC by computational simulations. |
Q38609992 | Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States. |
Q37285973 | Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer. |
Q44660604 | Decreased survival in EGFR gene amplified vulvar carcinoma |
Q40135901 | Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling. |
Q33671802 | Defining the blueprint of the cancer genome |
Q37834359 | Defining the cancer master switch |
Q42707531 | Defining the pathogenicity of DNA sequence variation |
Q35631635 | Defining the role of tyrosine kinase inhibitors in early stage non-small cell lung cancer. |
Q36088163 | Degradation of epidermal growth factor receptor mediates dasatinib-induced apoptosis in head and neck squamous cell carcinoma cells |
Q47314182 | Deguelin induces PUMA-mediated apoptosis and promotes sensitivity of lung cancer cells (LCCs) to doxorubicin (Dox). |
Q33779169 | Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis |
Q43518666 | Delivery of chemotherapy and antibodies across the blood-brain barrier and the role of chemoprotection, in primary and metastatic brain tumors: report of the Eleventh Annual Blood-Brain Barrier Consortium meeting |
Q58408122 | DeltaN TP63 reactivation, epithelial phenotype maintenance, and survival in lung squamous cell carcinoma |
Q58697688 | Demographic Composition of Select Oncologic New Molecular Entities Approved by the FDA Between 2008 and 2017 |
Q36690711 | Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry |
Q89867948 | Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death |
Q64059776 | Deregulation of a Network of mRNA and miRNA Genes Reveals That CK2 and MEK Inhibitors May Synergize to Induce Apoptosis KRAS-Active NSCLC |
Q33588217 | Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging |
Q54642118 | Design and generation of MLPA probe sets for combined copy number and small-mutation analysis of human genes: EGFR as an example. |
Q33936934 | Design and inference for cancer biomarker study with an outcome and auxiliary-dependent subsampling |
Q47623485 | Design, Synthesis, and Antitumor Activity of Novel Quinazoline Derivatives. |
Q35132338 | Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers |
Q82215956 | Designing prospective clinical pharmacogenomic (PG) trials: meeting report on drug development strategies to enhance therapeutic decision making |
Q91286819 | Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies |
Q99350140 | Destabilizing single chain major histocompatibility complex class I protein for repurposed enterokinase proteolysis |
Q34092187 | Detecting ALK, ROS1 and RET Fusion Genes in Cell Block Samples |
Q58695640 | Detecting EGFR mutations in patients with non-small cell lung cancer |
Q34589493 | Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer. |
Q36866974 | Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer |
Q43246506 | Detection of EGFR T790M Mutation in Pericardial Effusion from a Non-Small Cell Lung Cancer Patient with Erlotinib Therapy |
Q37313331 | Detection of EGFR gene mutations in non-small cell lung cancer: lessons from a single-institution routine analysis of 1,403 tumor samples |
Q35038358 | Detection of EGFR mutation in supernatant, cell pellets of pleural effusion and tumor tissues from non-small cell lung cancer patients by high resolution melting analysis and sequencing |
Q38398139 | Detection of EGFR mutations and EML4-ALK rearrangements in lung adenocarcinomas using archived cytological slides. |
Q33582524 | Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays. |
Q34467915 | Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer |
Q36787803 | Detection of EML4-ALK fusion gene and features associated with EGFR mutations in Chinese patients with non-small-cell lung cancer |
Q44509483 | Detection of EML4-ALK fusion genes in non-small cell lung cancer patients with clinical features associated with EGFR mutations |
Q37141952 | Detection of K-Ras mutations in tumour samples of patients with non-small cell lung cancer using PNA-mediated PCR clamping |
Q47879384 | Detection of an EGFR mutation in cytological specimens of lung adenocarcinoma. |
Q37709234 | Detection of circulating tumor DNA in patients with advanced non-small cell lung cancer |
Q36755219 | Detection of drug-sensitizing EGFR exon 19 deletion mutations in salivary gland carcinoma |
Q35787132 | Detection of epidermal growth factor receptor mutation in lung cancer by droplet digital polymerase chain reaction |
Q36278010 | Detection of epidermal growth factor receptor mutation in plasma as a biomarker in Chinese patients with early-stage non-small cell lung cancer |
Q39437297 | Detection of epidermal growth factor receptor mutations in a few cancer cells from transbronchial cytologic specimens by reverse transcriptase-polymerase chain reaction |
Q36835257 | Detection of epidermal growth factor receptor mutations in formalin fixed paraffin embedded biopsies in Malaysian non-small cell lung cancer patients. |
Q47093966 | Detection of epidermal growth factor receptor mutations in lung adenocarcinoma cytological specimens by immunocytochemistry |
Q42907464 | Detection of epidermal growth factor receptor mutations in non-small cell lung cancer tumor specimens from various ways by denaturing high-performance liquid chromatography |
Q39531710 | Detection of low-level EGFR T790M mutation in lung cancer tissues |
Q35789640 | Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma. |
Q29615033 | Detection of mutations in EGFR in circulating lung-cancer cells |
Q40251398 | Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors |
Q36138364 | Detection of rearrangement of anaplastic lymphoma kinase (ALK) and mutation of epidermal growth factor receptor (EGFR) in primary pulmonary lymphoepithelioma-like carcinoma |
Q46609599 | Detection of response-predicting mutations in the kinase domain of the epidermal growth factor receptor gene in cholangiocarcinomas |
Q36497457 | Detection of tumor PIK3CA status in metastatic breast cancer using peripheral blood |
Q33525226 | Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients |
Q37146779 | Determinants of survival in advanced non--small-cell lung cancer in the era of targeted therapies |
Q36085452 | Determination of EGFR and KRAS mutational status in Greek non-small-cell lung cancer patients |
Q34799198 | Determination of EGFR mutations in single cells microdissected from enriched lung tumor cells in peripheral blood. |
Q39129178 | Determining EGFR-TKI sensitivity of G719X and other uncommon EGFR mutations in non-small cell lung cancer: Perplexity and solution (Review). |
Q54272422 | Determining the profiles and parameters for gene amplification testing of growth factor receptors in lung cancer. |
Q97567723 | Development and validation of a predictive model for estimating EGFR mutation probabilities in patients with non-squamous non-small cell lung cancer in New Zealand |
Q91344944 | Development and validation of a targeted gene sequencing panel for application to disparate cancers |
Q35612289 | Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms |
Q35968389 | Development of TGF-beta signalling inhibitors for cancer therapy |
Q39319196 | Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma. |
Q38717500 | Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients. |
Q50246515 | Development of a skin rash within the first week and the therapeutic effect in afatinib monotherapy for EGFR-mutant non-small cell lung cancer (NSCLC): Okayama Lung Cancer Study Group experience. |
Q49802373 | Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours. |
Q37630493 | Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer |
Q34393558 | Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib |
Q38792120 | Development of crizotinib, a rationally designed tyrosine kinase inhibitor for non-small cell lung cancer |
Q38793056 | Development of indication criteria for preoperative examination in lung cancer |
Q37833005 | Development of molecularly targeted therapies in biliary tract cancers: reassessing the challenges and opportunities |
Q38956309 | Development of personalized treatments in lung cancer: focusing on the EGFR mutations and beyond. |
Q38930336 | Diagnosis and Molecular Classification of Lung Cancer |
Q33737293 | Diagnostic and Therapeutic Potential of MicroRNAs in Lung Cancer |
Q46624082 | Diagnostic value of a novel fully automated immunochemistry assay for detection of ALK rearrangement in primary lung adenocarcinoma |
Q35244225 | Diagnostic value of mutation-specific antibodies for immunohistochemical detection of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis |
Q52903547 | Diamond: immunohistochemistry versus sequencing in EGFR analysis of lung adenocarcinomas. |
Q37324081 | Dichotomy of cellular inhibition by small-molecule inhibitors revealed by single-cell analysis. |
Q49166137 | Diethylnitrosamine induces lung adenocarcinoma in FVB/N mouse. |
Q47118230 | Difference in Postsurgical Prognostic Factors between Lung Adenocarcinoma and Squamous Cell Carcinoma |
Q37177513 | Differences among lesions with exon 19, exon 21 EGFR mutations and wild types in surgically resected non-small cell lung cancer |
Q37269571 | Differences in EGFR and KRAS mutation spectra in lung adenocarcinoma of never and heavy smokers |
Q52145217 | Different EGFR Gene Mutations in Exon 18, 19 and 21 as Prognostic and Predictive Markers in NSCLC: A Single Institution Analysis. |
Q40016506 | Different spatial distributions of brain metastases from lung cancer by histological subtype and mutation status of epidermal growth factor receptor. |
Q39277085 | Different treatment orders achieved similar clinical results: a retrospective study for retreatment of epidermal growth factor receptor tyrosine kinase inhibitors in 120 patients with non-small-cell lung cancer |
Q35434274 | Differential Effects of Tyrosine Kinase Inhibitors on Normal and Oncogenic EGFR Signaling and Downstream Effectors |
Q90427149 | Differential Gene Expression in Erlotinib-Treated Fibroblasts |
Q58772425 | Differential MicroRNA Expression between EGFR T790M and L858R Mutated Lung Cancer |
Q90411020 | Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins |
Q41930710 | Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes |
Q40384212 | Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations |
Q36121683 | Differential efficacy of docetaxel according to non-small cell lung cancer histology and the therapeutic effect of epidermal growth factor receptor tyrosine kinase inhibitors |
Q45848152 | Differential expression and activation of epidermal growth factor receptor 1 (EGFR1), ERK, AKT, STAT3, and TWIST1 in nonsmall cell lung cancer (NSCLC). |
Q33733522 | Differential expression of CRKL and AXL genes in lung adenocarcinoma subtypes according to the epidermal growth factor receptor and anaplastic lymphoma kinase gene status |
Q41213157 | Differential expression of bone morphogenetic protein 5 in human lung squamous cell carcinoma and adenocarcinoma. |
Q39032624 | Differential parsing of EGFR endocytic flux among parallel internalization pathways in lung cancer cells with EGFR-activating mutations |
Q37708836 | Differential protein stability of EGFR mutants determines responsiveness to tyrosine kinase inhibitors |
Q39430288 | Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide |
Q43200792 | Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII. |
Q35967385 | Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors |
Q90193852 | Diffuse Lung Metastases in EGFR-Mutant Non-Small Cell Lung Cancer |
Q47208190 | Diffusion-Weighted Imaging of Brain Metastasis from Lung Cancer: Correlation of MRI Parameters with the Histologic Type and Gene Mutation Status. |
Q42131816 | Diminished functional role and altered localization of SHP2 in non-small cell lung cancer cells with EGFR-activating mutations |
Q64120213 | Direct activation of PP2A for the treatment of tyrosine kinase inhibitor-resistant lung adenocarcinoma |
Q36855852 | Direct interaction of avermectin with epidermal growth factor receptor mediates the penetration resistance in Drosophila larvae |
Q42652187 | Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer |
Q39478075 | Direct sequencing in cytological specimens as a useful strategy for detecting EGFR mutations in non-small cell lung cancer patients. |
Q38202550 | Discoidin domain receptors: a proteomic portrait |
Q36847104 | Discordance of Mutation Statuses of Epidermal Growth Factor Receptor and K-ras between Primary Adenocarcinoma of Lung and Brain Metastasis |
Q50050248 | Discordance of epidermal growth factor receptor mutations between primary tumors and corresponding mediastinal nodal metastases in patients operated on for stage N2 non-small cell lung cancer. |
Q38605171 | Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies. |
Q34152841 | Discovering tumor suppressor genes through genome-wide copy number analysis |
Q64075678 | Discovery Stories of RET Fusions in Lung Cancer: A Mini-Review |
Q39781895 | Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors |
Q30664020 | Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value |
Q33566948 | Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode |
Q93083358 | Discovery of JND3229 as a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy |
Q38829629 | Discovery of a dual-targeting organometallic ruthenium complex with high activity inducing early stage apoptosis of cancer cells |
Q38702793 | Discovery of a potent dual ALK and EGFR T790M inhibitor |
Q34701319 | Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutation |
Q99584571 | Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer |
Q37421181 | Disease diversity and FLT3 mutations |
Q44331655 | Disease flare after EGFR tyrosine kinase inhibitor cessation predicts poor survival in patients with non-small cell lung cancer |
Q96950911 | Disease-related cellular protein networks differentially affected under different EGFR mutations in lung adenocarcinoma |
Q37078736 | Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity |
Q60933000 | Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer |
Q36547770 | Dissecting cancer pathways and vulnerabilities with RNAi |
Q27851628 | Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling |
Q37285302 | Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. |
Q28537922 | Distinct clinical outcomes of non-small cell lung cancer patients with epidermal growth factor receptor (EGFR) mutations treated with EGFR tyrosine kinase inhibitors: non-responders versus responders |
Q36427883 | Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells |
Q42484909 | Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants |
Q46456054 | Distribution according to histologic type and outcome by gender and age group in Taiwanese patients with lung carcinoma. |
Q37328516 | Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells. |
Q51214174 | Diversity of epidermal growth factor receptor-mediated activation of downstream molecules in human lung carcinomas. |
Q37314999 | Divide and conquer: progress in the molecular stratification of cancer |
Q53792939 | Do EGFR tyrosine kinase inhibitors (TKIs) still have a role in EGFR wild-type pre-treated advanced non-small cell lung cancer (NSCLC)?-the shifting paradigm of therapeutics. |
Q55387219 | Docetaxel plus ramucirumab with primary prophylactic pegylated-granulocyte-colony stimulating factor for pretreated non-small cell lung cancer. |
Q42145859 | Does lung cancer mutation status and targeted therapy predict for outcomes and local control in the setting of brain metastases treated with radiation? |
Q39205689 | Does the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor differ according to the type of EGFR mutation in non-small cell lung cancer? |
Q35200480 | Does the order of factors affect the product? Lessons learned from the TORCH trial |
Q51576856 | Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer. |
Q37709570 | Dosing to rash: a phase II trial of the first-line erlotinib for patients with advanced non-small-cell lung cancer an Eastern Cooperative Oncology Group Study (E3503). |
Q28237711 | Double-stranded DNA in exosomes: a novel biomarker in cancer detection |
Q53556638 | Down Expression of FBP1 Is a Negative Prognostic Factor for Non-Small-Cell Lung Cancer. |
Q53622918 | Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells. |
Q24307767 | Downregulation and growth inhibitory role of FHL1 in lung cancer |
Q39510460 | Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling |
Q35227386 | Downregulation of ubiquitin inhibits the proliferation and radioresistance of non-small cell lung cancer cells in vitro and in vivo |
Q39048792 | Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer |
Q36498413 | Driven to metastasize: Kinases as potential therapeutic targets in prostate cancer |
Q37815607 | Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma |
Q36179400 | Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas |
Q59080774 | Drivers and passengers |
Q48263037 | Droplet digital PCR-based EGFR mutation detection with an internal quality control index to determine the quality of DNA. |
Q37282274 | Drug Insight: cetuximab in the treatment of recurrent and metastatic squamous cell carcinoma of the head and neck |
Q37174391 | Drug Insight: panitumumab, a human EGFR-targeted monoclonal antibody with promising clinical activity in colorectal cancer |
Q37634419 | Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma |
Q36834883 | Drug Resistance to EGFR Inhibitors in Lung Cancer |
Q39390532 | Drug Sensitivity Assays of Human Cancer Organoid Cultures |
Q35827606 | Drug development in oncology: classical cytotoxics and molecularly targeted agents |
Q37970537 | Drug development to overcome resistance to EGFR inhibitors in lung and colorectal cancer |
Q39493552 | Drug efficacy testing in mice |
Q36893554 | Drug insight: advances in renal cell carcinoma and the role of targeted therapies |
Q36040613 | Drug resistance and its significance for treatment decisions in non-small-cell lung cancer |
Q37008882 | Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents |
Q94317317 | Drug resistance in lung cancer |
Q28537830 | Drug resistance missense mutations in cancer are subject to evolutionary constraints |
Q36801208 | Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer |
Q45327788 | Drug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics |
Q38664437 | Drug-diagnostic co-development: challenges and issues |
Q36735178 | Drug-sensitive FGFR2 mutations in endometrial carcinoma |
Q33564782 | Drug-sensitive FGFR3 mutations in lung adenocarcinoma |
Q28079559 | Drugging the addict: non-oncogene addiction as a target for cancer therapy |
Q28254233 | Drugging the cancer kinome: progress and challenges in developing personalized molecular cancer therapeutics |
Q33860674 | Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells |
Q36258125 | Dual HER2/PIK3CA Targeting Overcomes Single-Agent Acquired Resistance in HER2-Amplified Uterine Serous Carcinoma Cell Lines In Vitro and In Vivo |
Q34122718 | Dual inhibition of EGFR and mTOR pathways in small cell lung cancer. |
Q37520544 | Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D. |
Q39091696 | Dual inhibition of MEK1/2 and EGFR synergistically induces caspase-3-dependent apoptosis in EGFR inhibitor-resistant lung cancer cells via BIM upregulation |
Q37382669 | Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations |
Q33759715 | Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells |
Q37363050 | Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer |
Q36273532 | Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype |
Q37126666 | DxS Ltd. |
Q41694055 | Dynamic circulating tumor DNA quantificaton for the individualization of non-small-cell lung cancer patients treatment. |
Q24294659 | Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA) |
Q42362771 | Dynamics of EGFR mutations in plasma recapitulates the clinical response to EGFR-TKIs in NSCLC patients |
Q36670951 | Dynamics of biological systems: role of systems biology in medical research |
Q36746250 | Dynamics of circulating tumor DNA represented by the activating and resistant mutations in epidermal growth factor receptor tyrosine kinase inhibitor treatment |
Q55334265 | Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer. |
Q44323391 | EFHD2 promotes epithelial-to-mesenchymal transition and correlates with postsurgical recurrence of stage I lung adenocarcinoma |
Q37438426 | EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells |
Q38951627 | EGF potentiation of VEGF production is cell density dependent in H292 EGFR wild type NSCLC cell line |
Q24561953 | EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib |
Q37799824 | EGF receptor in lung cancer: a successful story of targeted therapy |
Q38034817 | EGF receptor-targeted therapy in non-small-cell lung cancer: role of germline polymorphisms in outcome and toxicity |
Q29619032 | EGF-ERBB signalling: towards the systems level |
Q40235641 | EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer |
Q37043503 | EGF-receptor targeting with monoclonal antibodies in colorectal carcinomas: rationale for a pharmacogenomic approach |
Q57032248 | EGFR Amplification and Sensitizing Mutations Correlate with Survival in Lung Adenocarcinoma Patients Treated with Erlotinib (MutP-CLICaP) |
Q36044399 | EGFR Exon 18 Mutations in East Asian Patients with Lung Adenocarcinomas: A Comprehensive Investigation of Prevalence, Clinicopathologic Characteristics and Prognosis |
Q36971209 | EGFR Fusions as Novel Therapeutic Targets in Lung Cancer |
Q37240726 | EGFR Inhibition in the Treatment of Non-Small Cell Lung Cancer |
Q36244968 | EGFR Kinase Domain Duplication (EGFR-KDD) Is a Novel Oncogenic Driver in Lung Cancer That Is Clinically Responsive to Afatinib |
Q30397503 | EGFR L858M/L861Q cis Mutations Confer Selective Sensitivity to Afatinib |
Q35606916 | EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib. |
Q49959764 | EGFR Mutation Status in Lung Adenocarcinoma-Associated Malignant Pleural Effusion and Efficacy of EGFR Tyrosine Kinase Inhibitors. |
Q93183634 | EGFR Mutation Testing: Changing Patterns of Molecular Testing in Brazil |
Q36687288 | EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors |
Q33859707 | EGFR Mutations in Latinos From the United States and Latin America. |
Q91637156 | EGFR Polymorphism and Survival of NSCLC Patients Treated with TKIs: A Systematic Review and Meta-Analysis |
Q46411995 | EGFR R497K polymorphism is a favorable prognostic factor for advanced lung cancer |
Q34627605 | EGFR Signaling in Colorectal Carcinoma |
Q35040888 | EGFR T790M mutation as a possible target for immunotherapy; identification of HLA-A*0201-restricted T cell epitopes derived from the EGFR T790M mutation |
Q47836622 | EGFR T790M mutation testing of non-small cell lung cancer tissue and blood samples artificially spiked with circulating cell-free tumor DNA: results of a round robin trial. |
Q42701535 | EGFR T790M: revealing the secrets of a gatekeeper |
Q45886897 | EGFR TKI as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer |
Q39167752 | EGFR TKI combination with immunotherapy in non-small cell lung cancer |
Q99728118 | EGFR activity addiction facilitates anti-ERBB based combination treatment of squamous bladder cancer |
Q36048238 | EGFR and HER2 genomic gain in recurrent non-small cell lung cancer after surgery: impact on outcome to treatment with gefitinib and association with EGFR and KRAS mutations in a Japanese cohort |
Q36733618 | EGFR and HER2 signaling in breast cancer brain metastasis |
Q54495025 | EGFR and HER2-Akt-mTOR signaling pathways are activated in subgroups of salivary gland carcinomas. |
Q41829016 | EGFR and K-RAS mutations and ERCC1, TUBB3, TYMS, RRM1 and EGFR mRNA expression in non-small cell lung cancer: Correlation with clinical response to gefitinib or chemotherapy |
Q34346624 | EGFR and K-Ras mutations in women with lung adenocarcinoma: implications for treatment strategy definition |
Q36419182 | EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors? |
Q37790671 | EGFR and KRAS in colorectal cancer |
Q34096414 | EGFR and KRAS mutation analysis in cytologic samples of lung adenocarcinoma enabled by laser capture microdissection. |
Q47780922 | EGFR and KRAS mutations do not enrich for the activation of IL-6, JAK1 or phosphorylated STAT3 in resected lung adenocarcinoma. |
Q38391135 | EGFR and KRAS mutations in Turkish non-small cell lung cancer patients: a pilot study |
Q53238557 | EGFR and KRAS mutations in lung carcinoma: molecular testing by using cytology specimens. |
Q37205334 | EGFR and KRAS mutations in patients with adenocarcinoma of the lung |
Q38160089 | EGFR and KRAS mutations, and ALK fusions: current developments and personalized therapies for patients with advanced non-small-cell lung cancer. |
Q80647736 | EGFR and gastrointestinal stromal tumor: an immunohistochemical and FISH study of 82 cases |
Q46039810 | EGFR dinucleotide repeat polymorphism as a prognostic indicator in non-small cell lung cancer. |
Q33576802 | EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR. |
Q37021792 | EGFR exon 20 insertion mutations in lung adenocarcinomas: prevalence, molecular heterogeneity, and clinicopathologic characteristics. |
Q33963199 | EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications |
Q62127975 | EGFR exon mutation distribution and outcome in non-small-cell lung cancer: a Portuguese retrospective study |
Q33372792 | EGFR expression in gallbladder carcinoma in North America |
Q46513909 | EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations |
Q27851658 | EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target |
Q53249127 | EGFR gene copy number gain is related to high tumor SUV and frequent relapse after adjuvant chemotherapy in resected lung adenocarcinoma. |
Q40378678 | EGFR gene copy number heterogeneity in fine-needle aspiration cytology from breast carcinomas determined by chromogenic in situ hybridization |
Q38796569 | EGFR gene mutation in gastrointestinal stromal tumours. |
Q44690866 | EGFR gene mutations in patients with adenosquamous lung carcinoma. |
Q48014727 | EGFR heterogeneity and implications for therapeutic intervention in glioblastoma |
Q37180302 | EGFR inhibition in non-small cell lung cancer: current evidence and future directions |
Q24794815 | EGFR inhibition in non-small cell lung cancer: resistance, once again, rears its ugly head |
Q38257898 | EGFR inhibitors and autophagy in cancer treatment |
Q38120309 | EGFR inhibitors as the first-line systemic treatment for advanced non-small-cell lung cancer. |
Q43849261 | EGFR inhibitors for wild-type EGFR NSCLC: to use or not to use? |
Q37767383 | EGFR inhibitors in non-small cell lung cancer (NSCLC): the emerging role of the dual irreversible EGFR/HER2 inhibitor BIBW 2992. |
Q36306259 | EGFR inhibitors: what have we learned from the treatment of lung cancer? |
Q34008570 | EGFR isoforms and gene regulation in human endometrial cancer cells |
Q36772144 | EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment. |
Q36758325 | EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy |
Q37709182 | EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction. |
Q38554153 | EGFR kinase-dependent and kinase-independent roles in clear cell renal cell carcinoma |
Q37191983 | EGFR lung cancer mutants get specialized |
Q46717312 | EGFR mRNA is upregulated, but somatic mutations of the gene are hardly found in renal cell carcinoma in Japanese patients. |
Q41065727 | EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer |
Q53538486 | EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy. |
Q46055656 | EGFR mutation analysis in non-small-cell lung cancer : Experience from routine diagnostics |
Q46853023 | EGFR mutation in gefitinib-responsive small-cell lung cancer |
Q46484941 | EGFR mutation in kidney carcinoma confers sensitivity to gefitinib treatment: a case report. |
Q35164306 | EGFR mutation is a better predictor of response to tyrosine kinase inhibitors in non-small cell lung carcinoma than FISH, CISH, and immunohistochemistry |
Q80100696 | EGFR mutation of tumor and serum in gefitinib-treated patients with chemotherapy-naive non-small cell lung cancer |
Q34992513 | EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer |
Q58793364 | EGFR mutation status in Tunisian non-small-cell lung cancer patients evaluated by mutation-specific immunohistochemistry |
Q38053963 | EGFR mutation status in brain metastases of non-small cell lung carcinoma. |
Q36611944 | EGFR mutation status in tumour-derived DNA from pleural effusion fluid is a practical basis for predicting the response to gefitinib |
Q64109081 | EGFR mutation subtypes and response to immune checkpoint blockade treatment in non-small cell lung cancer |
Q38061599 | EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples |
Q45243918 | EGFR mutation testing practice in advanced non-small cell lung cancer |
Q38379393 | EGFR mutation testing using archival-stained smears in non-small cell lung carcinoma. |
Q36135844 | EGFR mutation: Significance as a stratification factor in the era of molecular-targeted therapy |
Q30664830 | EGFR mutational status in a large series of Caucasian European NSCLC patients: data from daily practice |
Q46236872 | EGFR mutations and HER2/3 protein expression and clinical outcome in Chinese advanced non-small cell lung cancer patients treated with gefitinib |
Q98938383 | EGFR mutations and ROS1 and ALK rearrangements in a large series of non-small cell cancer in South India |
Q83093506 | EGFR mutations and molecularly targeted therapy: a new era in the treatment of lung cancer |
Q37434212 | EGFR mutations are detected comparably in cytologic and surgical pathology specimens of nonsmall cell lung cancer |
Q46263820 | EGFR mutations are more frequent in well-differentiated than in poor-differentiated lung adenocarcinomas |
Q26852507 | EGFR mutations as a prognostic and predictive marker in non-small-cell lung cancer |
Q43238274 | EGFR mutations cause a lethal syndrome of epithelial dysfunction with progeroid features |
Q34688967 | EGFR mutations in Indian lung cancer patients: clinical correlation and outcome to EGFR targeted therapy |
Q54112709 | EGFR mutations in early-stage and advanced-stage lung adenocarcinoma: Analysis based on large-scale data from China. |
Q36579633 | EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression |
Q38515822 | EGFR mutations in lung cancer: from tissue testing to liquid biopsy |
Q35800614 | EGFR mutations in patients with brain metastases from lung cancer: association with the efficacy of gefitinib. |
Q37566609 | EGFR mutations in patients with lung adenocarcinoma in southwest China: are G719S/A and L861Q more likely detected in tumors derived from smokers? |
Q34167004 | EGFR mutations in patients with non-small cell lung cancer from mainland China and their relationships with clinicopathological features: a meta-analysis |
Q37421036 | EGFR mutations in surgically resected fresh specimens from 697 consecutive Chinese patients with non-small cell lung cancer and their relationships with clinical features. |
Q54117532 | EGFR mutations subset in Chinese lung squamous cell carcinoma patients. |
Q55502873 | EGFR overexpression is not common in patients with head and neck cancer. Cell lines are not representative for the clinical situation in this indication. |
Q51794333 | EGFR point mutation in non-small cell lung cancer is occasionally accompanied by a second mutation or amplification. |
Q36348040 | EGFR polymorphism as a predictor of clinical outcome in advanced lung cancer patients treated with EGFR-TKI. |
Q46653404 | EGFR polymorphisms, hormone replacement therapy and lung adenocarcinoma risk: analysis from a genome-wide association study in never-smoking women |
Q51744466 | EGFR protein overexpression and gene copy number increases in oral tongue squamous cell carcinoma. |
Q46054209 | EGFR protein overexpression and mutation in areca quid-associated oral cavity squamous cell carcinoma in Taiwan |
Q38171032 | EGFR signaling and autophagy dependence for growth, survival, and therapy resistance |
Q46677125 | EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids |
Q38552978 | EGFR targeted therapies and radiation: Optimizing efficacy by appropriate drug scheduling and patient selection |
Q24652337 | EGFR targeted therapy in non-small cell lung cancer: potential role of cetuximab |
Q34618994 | EGFR targeting drugs in the treatment of head and neck squamous cell carcinoma |
Q36557678 | EGFR testing and clinical management of advanced NSCLC: a Galician Lung Cancer Group study (GGCP 048-10) |
Q28243483 | EGFR testing in lung cancer is ready for prime time |
Q37177600 | EGFR tyrosine kinase inhibitors for the treatment of NSCLC in East Asia: present and future |
Q46837947 | EGFR tyrosine kinase inhibitors in non-small cell lung cancer: report of a 3-year compassionate use experience with gefitinib in stage IIIB/IV outpatients |
Q37393940 | EGFR tyrosine kinase inhibitors versus chemotherapy as first-line therapy for non-small cell lung cancer patients with the L858R point mutation |
Q38089244 | EGFR tyrosine kinase inhibitors: a therapy for a few, for the majority or for all non-small cell lung cancer patients? |
Q38106905 | EGFR tyrosine kinase inhibitors: difference in efficacy and resistance |
Q39362508 | EGFR tyrosine kinase mutation testing in the treatment of non-small-cell lung cancer |
Q39538057 | EGFR upregulates inflammatory and proliferative responses in human lung adenocarcinoma cell line (A549), induced by lower dose of cadmium chloride |
Q42731684 | EGFR with TKI-sensitive mutations in exon 19 is highly expressed and frequently detected in Chinese patients with lung squamous carcinoma |
Q37561771 | EGFR(S) inhibitors in the treatment of gastro-intestinal cancers: what's new? |
Q36741251 | EGFR, ALK, RET, KRAS and BRAF alterations in never-smokers with non-small cell lung cancer |
Q35893808 | EGFR, CD10 and proliferation marker Ki67 expression in ameloblastoma: possible role in local recurrence |
Q36947038 | EGFR, HER2 and VEGF pathways: validated targets for cancer treatment |
Q33727426 | EGFR, PIK3CA, KRAS and BRAF mutations in meningiomas |
Q38807586 | EGFR-GRB2 Protein Colocalization Is a Prognostic Factor Unrelated to Overall EGFR Expression or EGFR Mutation in Lung Adenocarcinoma |
Q90224747 | EGFR-Specific Tyrosine Kinase Inhibitor Modifies NK Cell-Mediated Antitumoral Activity against Ovarian Cancer Cells |
Q36285611 | EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity |
Q40562646 | EGFR-TKI rechallenge with bevacizumab in EGFR-mutant non-small cell lung cancer |
Q53698558 | EGFR-TKI resistance and MAP17 are associated with cancer stem cell like properties. |
Q30871237 | EGFR-TKI therapy for patients with brain metastases from non-small-cell lung cancer: a pooled analysis of published data |
Q57485837 | EGFR-TKI-sensitive mutations in lung carcinomas: are they related to clinical features and CT findings? |
Q37538757 | EGFR-directed therapies to treat non-small-cell lung cancer |
Q24335999 | EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance |
Q60449321 | EGFR-mutant lung adenocarcinoma in a patient with Li-Fraumeni syndrome |
Q24606177 | EGFR-mutant lung adenocarcinomas treated first-line with the novel EGFR inhibitor, XL647, can subsequently retain moderate sensitivity to erlotinib |
Q34406334 | EGFR-mutated lung cancer: a paradigm of molecular oncology |
Q37160173 | EGFR-targeted therapies in lung cancer: predictors of response and toxicity |
Q36619212 | EGFR-targeted therapy for non-small cell lung cancer: focus on EGFR oncogenic mutation |
Q37682778 | EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models |
Q36826056 | EGFR-tyrosine kinase inhibitor treatment in a patient with advanced non-small cell lung cancer and concurrent exon 19 and 21 EGFR mutations: A case report and review of the literature |
Q37206247 | EGFR/HER2 in breast cancer: a biological approach for molecular diagnosis and therapy |
Q46640557 | EGFR/KRAS mutations and gefitinib therapy in Chinese NSCLC patients |
Q35619241 | EGFR: The Paradigm of an Oncogene-Driven Lung Cancer |
Q80100754 | EGFR: a prognostic and/or a predictive marker? |
Q35078031 | EGFRvIII mediates hepatocellular carcinoma cell invasion by promoting S100 calcium binding protein A11 expression |
Q55457200 | EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival. |
Q34356008 | EGFs and ERBBs--brief history and prospects |
Q35730962 | EML4-ALK fusion gene in Korean non-small cell lung cancer |
Q46113744 | EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. |
Q24645724 | EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues |
Q36335816 | EML4-ALK translocation is associated with early onset of disease and other clinicopathological features in Chinese female never-smokers with non-small-cell lung cancer |
Q54727452 | EML4-ALK: honing in on a new target in non-small-cell lung cancer. |
Q39220097 | EMP-1 promotes tumorigenesis of NSCLC through PI3K/AKT pathway |
Q37589341 | EORTC Elderly Task Force and Lung Cancer Group and International Society for Geriatric Oncology (SIOG) experts' opinion for the treatment of non-small-cell lung cancer in an elderly population. |
Q38805633 | EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer |
Q35532215 | EPMA position paper in cancer: current overview and future perspectives |
Q36355962 | ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma |
Q29619520 | ERBB receptors and cancer: the complexity of targeted inhibitors |
Q33601653 | ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics |
Q90101145 | ERBB3 mutations in cancer: biological aspects, prevalence and therapeutics |
Q38919117 | ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas |
Q37337542 | ERBBs in the gastrointestinal tract: recent progress and new perspectives |
Q85303113 | ERCC1 and the efficacy of cisplatin in patients with resected non-small cell lung cancer |
Q99419149 | EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy |
Q52649612 | ERK inhibition represses gefitinib resistance in non-small cell lung cancer cells. |
Q37661108 | ERK1/2 blockade prevents epithelial-mesenchymal transition in lung cancer cells and promotes their sensitivity to EGFR inhibition |
Q28741454 | EZH2 codon 641 mutations are common in BCL2-rearranged germinal center B cell lymphomas |
Q33392707 | Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET). |
Q33947163 | Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells |
Q54113607 | Early radiological response as predictor of overall survival in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor mutations. |
Q35571704 | Eastern Cooperative Oncology Group Phase II Trial of lapatinib in men with biochemically relapsed, androgen dependent prostate cancer |
Q36439557 | Echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase rearrangement and epidermal growth factor receptor mutation coexisting in Chinese patients with lung adenocarcinoma |
Q26747510 | Ectopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic Instability |
Q58545847 | Effect Sizes of Somatic Mutations in Cancer |
Q64109900 | Effect of Cetuximab and Small Interfering RNA Combination Treatment in NSCLC Cell Lines with Wild Type and Use of as a Possible Biomarker for Treatment Responsiveness |
Q64072904 | Effect of EGFR gene polymorphism on efficacy of chemotherapy combined with targeted therapy for non-small cell lung cancer in Chinese patients |
Q79782947 | Effect of ERCC1 polymorphisms and the modification by smoking on the survival of non-small cell lung cancer patients |
Q53519220 | Effect of Sustained Elevated Gastric pH Levels on Gefitinib Exposure. |
Q40337329 | Effect of adding gefitinib to neoadjuvant chemotherapy in estrogen receptor negative early breast cancer in a randomized phase II trial |
Q36524729 | Effect of hydrothorax EGFR gene mutation and EGFR-TKI targeted therapy on advanced non-small cell lung cancer patients |
Q37090804 | Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice |
Q92298178 | Effect of miR-140-5p on the regulation of proliferation and apoptosis in NSCLC and its underlying mechanism |
Q35221485 | Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM. |
Q35699603 | Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition |
Q38634910 | Effect of smoking status on progression-free and overall survival in non-small cell lung cancer patients receiving erlotinib or gefitinib: a meta-analysis |
Q54973430 | Effective osimertinib treatment in a patient with discordant T790 M mutation detection between liquid biopsy and tissue biopsy. |
Q54979668 | Effectiveness of afatinib after ineffectiveness of gefitinib in an advanced lung adenocarcinoma patient with a single EGFR exon 20 S768I mutation: a case report. |
Q34041701 | Effectiveness of gefitinib against non-small-cell lung cancer with the uncommon EGFR mutations G719X and L861Q. |
Q38956327 | Effectiveness of maintenance treatments for nonsmall cell lung cancer |
Q36036046 | Effects of AKT inhibition on HGF-mediated erlotinib resistance in non-small cell lung cancer cell lines |
Q37389605 | Effects of epidermal growth factor receptor-tyrosine kinase inhibitors alone on EGFR-mutant non-small cell lung cancer with brain metastasis |
Q37000538 | Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib |
Q54356532 | Effects of icotinib on advanced non-small cell lung cancer with different EGFR phenotypes. |
Q36733598 | Effects of icotinib on early-stage non-small-cell lung cancer as neoadjuvant treatment with different epidermal growth factor receptor phenotypes |
Q36967631 | Effects of oncogenic mutations on the conformational free-energy landscape of EGFR kinase |
Q89092109 | Efficacy and Safety of Afatinib for EGFR-mutant Non-small Cell Lung Cancer, Compared with Gefitinib or Erlotinib |
Q36631504 | Efficacy and safety of icotinib as first-line therapy in patients with advanced non-small-cell lung cancer |
Q36924484 | Efficacy and safety of icotinib in patients with brain metastases from lung adenocarcinoma |
Q54210501 | Efficacy of EGFR tyrosine kinase inhibitors for non-adenocarcinoma lung cancer patients harboring EGFR-sensitizing mutations in China. |
Q54347207 | Efficacy of S-1 plus nedaplatin compared to standard second-line chemotherapy in EGFR-negative lung adenocarcinoma after failure of first-line chemotherapy. |
Q34050239 | Efficacy of bevacizumab plus erlotinib versus erlotinib alone in advanced non-small-cell lung cancer after failure of standard first-line chemotherapy (BeTa): a double-blind, placebo-controlled, phase 3 trial |
Q36247866 | Efficacy of bronchoscopic biopsy for the detection of epidermal growth factor receptor mutations and anaplastic lymphoma kinase gene rearrangement in lung adenocarcinoma |
Q46008308 | Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study. |
Q36616462 | Efficacy of epidermal growth factor receptor-targeted molecular therapy in anaplastic thyroid cancer cell lines |
Q41099007 | Efficacy of erlotinib in previously treated patients with advanced non-small cell lung cancer: analysis of the Chinese subpopulation in the TRUST study |
Q52893820 | Efficacy of icotinib in lung squamous-cell cancer: A real-world experience from single institution. |
Q35233470 | Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation |
Q36351290 | Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A. |
Q33485003 | Efficacy of sorafenib on metastatic renal cell carcinoma in Asian patients: results from a multicenter study |
Q34785940 | Efficacy of third-line pemetrexed monotherapy versus pemetrexed combination with bevacizumab in patients with advanced EGFR mutation-positive lung adenocarcinoma |
Q51296848 | Efficacy, safety, and survival factors for sorafenib treatment in Japanese patients with advanced hepatocellular carcinoma. |
Q36438421 | Elderly male smokers with right lung tumors are viable candidates for KRAS mutation screening |
Q36116287 | Electrical detection of cancer biomarker using aptamers with nanogap break-junctions |
Q92134578 | Elemental and mutational analysis of lung tissue in lung adenocarcinoma patients |
Q35064133 | Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells |
Q39971699 | Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma |
Q39828170 | Elevated integrin α6β4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer. |
Q37099888 | Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer |
Q39473591 | Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients |
Q43261058 | Elevated serum levels of TPS and CYFRA 21-1 predict poor prognosis in advanced non-small-cell lung cancer patients treated with gefitinib |
Q35948915 | Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs |
Q79886528 | Elevation of soluble interleukin-2 receptor in patients with non-small cell lung cancer treated with gefitinib |
Q37691441 | Emerging MEK inhibitors. |
Q37588717 | Emerging Raf inhibitors. |
Q98944239 | Emerging Therapies in Thoracic Malignancies-Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non-Small Cell Lung Cancer |
Q38623361 | Emerging anti-cancer antibodies and combination therapies targeting HER3/ERBB3. |
Q36758593 | Emerging drugs for mesothelioma |
Q36944022 | Emerging drugs for targeted therapy of bladder cancer. |
Q35914897 | Emerging insights into the molecular and cellular basis of glioblastoma |
Q37848663 | Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer |
Q36084718 | Emerging molecular classification in renal cell carcinoma: implications for drug development |
Q38642455 | Emerging molecular targets and therapy for cholangiocarcinoma |
Q37269316 | Emerging options for the management of non-small cell lung cancer |
Q37249366 | Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer |
Q45216006 | Emerging role of erlotinib (OSI-774) in non-small-cell lung cancer. |
Q33892582 | Emerging role of gefitinib in the treatment of non-small-cell lung cancer (NSCLC). |
Q28078928 | Emerging roles of Nrf2 signal in non-small cell lung cancer |
Q35988130 | Emerging strategies and applications of pharmacogenomics |
Q35008971 | Emerging tactical strategies for fighting the war on cancer based on the genetic landscape |
Q28070165 | Emerging therapeutic agents for lung cancer |
Q37030800 | Emerging therapies for malignant glioma |
Q64089193 | Emerging therapies for non-small cell lung cancer |
Q34483953 | Emerging treatment for advanced lung cancer with EGFR mutation |
Q36228352 | Emerging treatment options for patients with recurrent advanced thymic epithelial tumors |
Q36519807 | Emerging treatments for choroidal metastases |
Q46071509 | Emerging uses of biomarkers in lung cancer management: molecular mechanisms of resistance |
Q39841334 | Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation |
Q42869980 | Endocytosis and cancer |
Q37549617 | Endocytosis and signalling: a meeting with mathematics |
Q38892107 | Endothelial PAS domain-containing protein 1 confers TKI-resistance by mediating EGFR and MET pathways in non-small cell lung cancer cells |
Q37129376 | Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR |
Q46424042 | Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells |
Q35051626 | Enhanced anti-angiogenic effect of E7820 in combination with erlotinib in epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer xenograft models |
Q39124519 | Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer |
Q27305848 | Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer |
Q36484536 | Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status |
Q33648864 | Epidemiological features of lung giant cell carcinoma and therapy for patients with EGFR mutations based on case reports and the surveillance, epidemiology, and end results (SEER) database |
Q39363203 | Epidemiological profile and prognostic factors in patients with lung cancer |
Q36337982 | Epidemiology informing clinical practice: from bills of mortality to population laboratories |
Q90150760 | Epidermal Growth Factor Receptor (EGFR) Gene Mutation Analysis in Adenocarcinoma of Lung, the First Report from Iran |
Q47261688 | Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors and Non-Small Cell Lung Cancer (NSCLC) - Advances in Molecular Diagnostic Techniques to Facilitate Targeted Therapy. |
Q36322658 | Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy |
Q92454757 | Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC) |
Q33803406 | Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer |
Q33737298 | Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways |
Q47614764 | Epidermal Growth Factor Receptor Expression Predicts Time and Patterns of Recurrence in Patients with Glioblastoma After Radiotherapy and Temozolomide |
Q58567008 | Epidermal Growth Factor Receptor Gene in Non-Small-Cell Lung Cancer: The Importance of Promoter Polymorphism Investigation |
Q36040002 | Epidermal Growth Factor Receptor Mutation (EGFR) Testing for Prediction of Response to EGFR-Targeting Tyrosine Kinase Inhibitor (TKI) Drugs in Patients with Advanced Non-Small-Cell Lung Cancer: An Evidence-Based Analysis |
Q38460428 | Epidermal Growth Factor Receptor Mutation Status in the Treatment of Non-small Cell Lung Cancer: Lessons Learned |
Q80393070 | Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha |
Q36239648 | Epidermal growth factor inhibition in solid tumours |
Q57692990 | Epidermal growth factor ligand/receptor loop and downstream signaling activation pattern in completely resected nonsmall cell lung cancer |
Q40212739 | Epidermal growth factor receptor (EGFR) antibody down-regulates mutant receptors and inhibits tumors expressing EGFR mutations |
Q33302191 | Epidermal growth factor receptor (EGFR) gene copy number detection in non-small-cell lung cancer; a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization. |
Q36485352 | Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry. |
Q35667627 | Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update |
Q36458742 | Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy |
Q39828582 | Epidermal growth factor receptor (EGFR) mutation and p-EGFR expression in resected non-small cell lung cancer |
Q28284519 | Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC) |
Q34781380 | Epidermal growth factor receptor (EGFR) mutations are exceptionally rare in thyroid transcription factor (TTF-1)-negative adenocarcinomas of the lung. |
Q54361563 | Epidermal growth factor receptor (EGFR) mutations as biomarker for head and neck squamous cell carcinomas (HNSCC). |
Q82500381 | Epidermal growth factor receptor (EGFR) mutations in a series of non-small-cell lung cancer (NSCLC) patients and response rate to EGFR-specific tyrosine kinase inhibitors (TKIs) |
Q30850656 | Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data. |
Q39254692 | Epidermal growth factor receptor (EGFR): A rising star in the era of precision medicine of lung cancer. |
Q44740671 | Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy |
Q47116265 | Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFR-mutant non-small cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors |
Q36014004 | Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas |
Q27865182 | Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain |
Q42818168 | Epidermal growth factor receptor activation in prostate cancer by three novel missense mutations |
Q33575439 | Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas |
Q35549063 | Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies |
Q36907221 | Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors |
Q35956330 | Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients |
Q54494664 | Epidermal growth factor receptor and Kras gene expression: reliability of mutational analysis on cytological samples. |
Q38995524 | Epidermal growth factor receptor and anaplastic lymphoma kinase testing and mutation prevalence in patients with advanced non-small cell lung cancer in Switzerland: A comprehensive evaluation of real world practices |
Q37790320 | Epidermal growth factor receptor and mammalian target of rapamycin as therapeutic targets in malignant glioma: current clinical status and perspectives |
Q28080187 | Epidermal growth factor receptor and notch signaling in non-small-cell lung cancer |
Q36653667 | Epidermal growth factor receptor as a major anticancer drug target |
Q34195184 | Epidermal growth factor receptor copy number in potentially malignant oral disorders and oral squamous cell carcinoma: a short communication and preliminary study. |
Q46679323 | Epidermal growth factor receptor domain II, IV, and kinase domain mutations in human solid tumors |
Q40448827 | Epidermal growth factor receptor double targeting by a tyrosine kinase inhibitor (Iressa) and a monoclonal antibody (Cetuximab). Impact on cell growth and molecular factors. |
Q36728450 | Epidermal growth factor receptor exon 20 insertions in advanced lung adenocarcinomas: Clinical outcomes and response to erlotinib |
Q36503084 | Epidermal growth factor receptor exon 20 p.S768I mutation in non-small cell lung carcinoma: A case report combined with a review of the literature and investigation of clinical significance |
Q46371923 | Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy |
Q40332214 | Epidermal growth factor receptor expression and activation in neuroendocrine tumours |
Q34411696 | Epidermal growth factor receptor expression and gene amplification in colorectal carcinoma: an immunohistochemical and chromogenic in situ hybridization study |
Q42052616 | Epidermal growth factor receptor expression and gene copy number analysis in gastric carcinoma samples from Chinese patients |
Q39335663 | Epidermal growth factor receptor expression in acute myelogenous leukaemia is associated with clinical prognosis |
Q33691211 | Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes |
Q81414066 | Epidermal growth factor receptor expression in renal cell carcinoma: rationale for therapy with sidling blockade |
Q92134583 | Epidermal growth factor receptor first generation tyrosine-kinase inhibitors |
Q44485092 | Epidermal growth factor receptor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer |
Q33942092 | Epidermal growth factor receptor gene amplification in atypical adenomatous hyperplasia of the lung. |
Q34557318 | Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer |
Q40756893 | Epidermal growth factor receptor gene mutation as risk factor for recurrence in patients with surgically resected lung adenocarcinoma: a matched-pair analysis |
Q54538613 | Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma. |
Q80584656 | Epidermal growth factor receptor gene mutations in atypical adenomatous hyperplasias of the lung |
Q57075013 | Epidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro |
Q44051250 | Epidermal growth factor receptor gene mutations in papillary thyroid carcinoma |
Q35164907 | Epidermal growth factor receptor gene mutations in patients with lung adenocarcinoma differ by frequency and type between Uighur and Han ethnic groups in Xinjiang Autonomous Region |
Q37476827 | Epidermal growth factor receptor genomic variation in NSCLC patients receiving tyrosine kinase inhibitor therapy: a systematic review and meta-analysis |
Q28084216 | Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer |
Q54416267 | Epidermal growth factor receptor in adrenocortical tumors: analysis of gene sequence, protein expression and correlation with clinical outcome. |
Q35642677 | Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations. |
Q34105339 | Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance |
Q28088636 | Epidermal growth factor receptor in non-small cell lung cancer |
Q37132640 | Epidermal growth factor receptor in pancreatic cancer. |
Q37634598 | Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer |
Q35013457 | Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy |
Q36504349 | Epidermal growth factor receptor inhibition and non-small cell lung cancer |
Q36071392 | Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy |
Q28475894 | Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy |
Q36482542 | Epidermal growth factor receptor inhibitors and antiangiogenic agents for the treatment of non-small cell lung cancer |
Q36157284 | Epidermal growth factor receptor inhibitors and their role in non-small-cell lung cancer |
Q36429442 | Epidermal growth factor receptor inhibitors in cancer treatment. |
Q34382797 | Epidermal growth factor receptor inhibitors in colorectal cancer treatment: what's new? |
Q36830108 | Epidermal growth factor receptor inhibitors in non-small cell lung cancer |
Q38088756 | Epidermal growth factor receptor inhibitors in non-small-cell lung cancer |
Q36302860 | Epidermal growth factor receptor inhibitors in the treatment of non-small cell lung cancer |
Q35222011 | Epidermal growth factor receptor is a critical mediator of ultraviolet B irradiation-induced signal transduction in immortalized human keratinocyte HaCaT cells |
Q43555541 | Epidermal growth factor receptor is associated with the onset of skeletal related events in non-small cell lung cancer |
Q37123445 | Epidermal growth factor receptor kinase domain mutations are rare in salivary gland carcinomas |
Q37252270 | Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas |
Q35812818 | Epidermal growth factor receptor mutation analysis in cytological specimens and responsiveness to gefitinib in advanced non-small cell lung cancer patients |
Q37719929 | Epidermal growth factor receptor mutation and diverse tumors: case report and concise literature review |
Q37265114 | Epidermal growth factor receptor mutation in adenocarcinoma lung in a North Indian population: Prevalence and relation with different clinical variables |
Q33824203 | Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity |
Q37102688 | Epidermal growth factor receptor mutation in lung adenocarcinoma in India: A single center study |
Q34676580 | Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung |
Q50096967 | Epidermal growth factor receptor mutation status is strongly associated with smoking status in patients undergoing surgical resection for lung adenocarcinoma. |
Q44669701 | Epidermal growth factor receptor mutation subtypes and geographical distribution among Indian non-small cell lung cancer patients |
Q45272652 | Epidermal growth factor receptor mutation, but not sex and smoking, is independently associated with favorable prognosis of gefitinib-treated patients with lung adenocarcinoma |
Q54569001 | Epidermal growth factor receptor mutation-guided treatment for lung cancers: Where are we now? |
Q54395887 | Epidermal growth factor receptor mutation-specific immunohistochemical antibodies in lung adenocarcinoma. |
Q33617464 | Epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangements in lung cancer with nodular ground-glass opacity |
Q34575299 | Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer |
Q37232048 | Epidermal growth factor receptor mutations and the clinical outcome in male smokers with squamous cell carcinoma of lung |
Q51491538 | Epidermal growth factor receptor mutations as a prognostic factor in Korean patients with advanced lung adenocarcinoma who had not been treated with received epidermal growth factor receptor tyrosine kinase inhibitors. |
Q84409820 | Epidermal growth factor receptor mutations detected by denaturing high-performance liquid chromatography in nonsmall cell lung cancer: impact on response to therapy with epidermal growth factor receptor-tyrosine kinase inhibitors |
Q58082495 | Epidermal growth factor receptor mutations in Chinese patients with laryngeal squamous cell carcinoma |
Q54179471 | Epidermal growth factor receptor mutations in East European non-small cell lung cancer patients. |
Q38174770 | Epidermal growth factor receptor mutations in lung adenocarcinoma |
Q29615474 | Epidermal growth factor receptor mutations in lung cancer |
Q36817294 | Epidermal growth factor receptor mutations in lung cancers. |
Q39918647 | Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling |
Q36662504 | Epidermal growth factor receptor mutations in nonsmall cell lung carcinoma patients in Kuwait |
Q53270990 | Epidermal growth factor receptor mutations in patients with oral cavity cancer in a betel nut chewing-prevalent area. |
Q36429519 | Epidermal growth factor receptor mutations predict sensitivity to gefitinib in patients with non-small-cell lung cancer |
Q40190070 | Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma |
Q53564370 | Epidermal growth factor receptor polymorphisms and clinical outcomes in non-small-cell lung cancer patients treated with gefitinib. |
Q33996096 | Epidermal growth factor receptor polymorphisms and risk for toxicity in paediatric patients treated with gefitinib |
Q43407740 | Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma |
Q39739616 | Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells |
Q39752055 | Epidermal growth factor receptor signaling in nonsmall cell lung cancer |
Q34561698 | Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway |
Q38207484 | Epidermal growth factor receptor signalling in keratinocyte biology: implications for skin toxicity of tyrosine kinase inhibitors |
Q49468021 | Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer. |
Q36014238 | Epidermal growth factor receptor status in anaplastic thyroid carcinoma |
Q33315034 | Epidermal growth factor receptor structural alterations in gastric cancer |
Q34159125 | Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck |
Q39165055 | Epidermal growth factor receptor tyrosine kinase inhibition up-regulates interleukin-6 in cancer cells and induces subsequent development of interstitial pneumonia |
Q36660669 | Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease |
Q34031229 | Epidermal growth factor receptor tyrosine kinase inhibitors for non-small cell lung cancer |
Q38763111 | Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of central nervous system metastases from non-small cell lung cancer: the present and the future |
Q24653036 | Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer: results and open issues |
Q37431620 | Epidermal growth factor receptor tyrosine kinase inhibitors in elderly or poor performance status patients with advanced non-small cell lung cancer |
Q38594474 | Epidermal growth factor receptor tyrosine kinase inhibitors in elderly patients with non-small cell lung cancer |
Q35290807 | Epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: a decade of progress and hopeful future |
Q38701670 | Epidermal growth factor receptor tyrosine kinase inhibitors in previously treated advanced non-small-cell lung cancer with wild-type EGFR. |
Q36402837 | Epidermal growth factor receptor tyrosine kinase inhibitors with conventional chemotherapy for the treatment of non-small cell lung cancer |
Q38168795 | Epidermal growth factor receptor tyrosine-kinase inhibitor treatment resistance in non-small cell lung cancer: biological basis and therapeutic strategies |
Q34589789 | Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors |
Q36493232 | Epidermal growth factor receptor-targeted agents for lung cancer |
Q40038133 | Epidermal growth factor receptor-targeted therapy. |
Q36119978 | Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma |
Q38888532 | Epidermal growth factor receptor-tyrosine kinase inhibitor therapy is especially beneficial to patients with exon 19 deletion compared with exon 21 L858R mutation in non-small-cell lung cancer: Systematic review and meta analysis |
Q54329048 | Epidermal growth factor receptor-tyrosine kinase inhibitors in advanced squamous cell carcinoma of the lung: a meta-analysis. |
Q90886378 | Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics |
Q33779882 | Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized |
Q36042698 | Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer. |
Q36938216 | Epigenetic Therapy in Lung Cancer - Role of microRNAs |
Q38150749 | Epistatic interactions and drug response |
Q82917858 | Epithelial growth factor receptor status in primary and recurrent ovarian cancer |
Q24535592 | Epithelial membrane protein-1 is a biomarker of gefitinib resistance. |
Q37977436 | Epithelial mesenchymal transition and lung cancer |
Q36399326 | Epithelial-mesenchymal transition in lung cancer: is tobacco the "smoking gun"? |
Q34095970 | Epithelioid sarcoma expresses epidermal growth factor receptor but gene amplification and kinase domain mutations are rare. |
Q38729111 | ErbB Family Signalling: A Paradigm for Oncogene Addiction and Personalized Oncology |
Q37668848 | ErbB Proteins as Molecular Target of Dietary Phytochemicals in Malignant Diseases |
Q37970020 | ErbB family receptor inhibitors as therapeutic agents in breast cancer: current status and future clinical perspective |
Q36545883 | ErbB receptor negative regulatory mechanisms: implications in cancer |
Q36677496 | ErbB receptors and epithelial-cadherin-catenin complex in human carcinomas |
Q24683709 | ErbB receptors: from oncogenes to targeted cancer therapies |
Q33928631 | ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines |
Q37249978 | ErbBs in lung cancer |
Q37419295 | Eribulin sensitizes oral squamous cell carcinoma cells to cetuximab via induction of mesenchymal-to-epithelial transition. |
Q35263024 | Erlotinib 'dosing-to-rash': a phase II intrapatient dose escalation and pharmacologic study of erlotinib in previously treated advanced non-small cell lung cancer |
Q40161836 | Erlotinib (OSI-774)-induced inhibition of transitional cell carcinoma of bladder cell line growth is enhanced by interferon-alpha |
Q38245038 | Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 study |
Q38841850 | Erlotinib and gefitinib responsiveness in head and neck cancer cell lines--a comparing analysis with cetuximab. |
Q33945734 | Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations |
Q24685474 | Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth |
Q54616855 | Erlotinib efficacy and cerebrospinal fluid concentration in patients with lung adenocarcinoma developing leptomeningeal metastases during gefitinib therapy. |
Q36425173 | Erlotinib eradicates brain metastases from epidermal growth factor receptor mutant non-small cell lung cancer |
Q36224756 | Erlotinib has better efficacy than gefitinib in adenocarcinoma patients without EGFR-activating mutations, but similar efficacy in patients with EGFR-activating mutations. |
Q43955796 | Erlotinib hydrochloride |
Q34266864 | Erlotinib in African Americans with advanced non-small cell lung cancer: a prospective randomized study with genetic and pharmacokinetic analyses. |
Q36161290 | Erlotinib in non-small cell lung cancer: a review |
Q36968183 | Erlotinib in non-small-cell lung cancer |
Q48597941 | Erlotinib in patients with advanced lung squamous cell carcinoma. |
Q35628121 | Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians |
Q37307567 | Erlotinib in the treatment of advanced pancreatic cancer |
Q36284485 | Erlotinib in the treatment of non-small cell lung cancer |
Q37290401 | Erlotinib in wild type epidermal growth factor receptor non-small cell lung cancer: A systematic review |
Q39975225 | Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK. |
Q33275026 | Erlotinib inhibits growth of a patient-derived chordoma xenograft |
Q35558557 | Erlotinib is a viable treatment for tumors with acquired resistance to cetuximab |
Q36228534 | Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial |
Q36151475 | Erlotinib plus capecitabine as first-line treatment for older Chinese patients with advanced adenocarcinoma of the lung (C-TONG0807): an open-label, single arm, multicenter phase II study |
Q39121775 | Erlotinib resistance in EGFR-amplified glioblastoma cells is associated with upregulation of EGFRvIII and PI3Kp110δ. |
Q42017054 | Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma |
Q34134464 | Erlotinib response in an NSCLC patient with a novel compound G719D+L861R mutation in EGFR. |
Q35996048 | Erlotinib therapy after initial platinum doublet therapy in patients with EGFR wild type non-small cell lung cancer: results of a combined patient-level analysis of the NCIC CTG BR.21 and SATURN trials |
Q34657690 | Erlotinib usage after prior treatment with gefitinib in advanced non-small cell lung cancer: A clinical perspective and review of published literature |
Q46542092 | Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial |
Q27851712 | Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial |
Q35152542 | Erlotinib-cisplatin combination inhibits growth and angiogenesis through c-MYC and HIF-1α in EGFR-mutated lung cancer in vitro and in vivo |
Q37754925 | Erlotinib: an EGF receptor tyrosine kinase inhibitor in non-small-cell lung cancer treatment |
Q36839754 | Erlotinib: success of a molecularly targeted agent for the treatment of advanced pancreatic cancer |
Q38970911 | Esophageal carcinoma cell line with high EGFR polysomy is responsive to gefitinib |
Q38694441 | Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure |
Q36834539 | Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient. |
Q35921330 | Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation |
Q37028611 | Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies |
Q41672200 | Estimation of age-related DNA degradation from formalin-fixed and paraffin-embedded tissue according to the extraction methods |
Q35051314 | Estrogen adversely affects the prognosis of patients with lung adenocarcinoma. |
Q38434138 | Estrogen receptor signaling pathways in human non-small cell lung cancer |
Q33561588 | Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatme |
Q34657570 | Estrogen receptors as the novel therapeutic biomarker in non-small cell lung cancer |
Q41171803 | Ethics of mandatory research biopsy for correlative end points within clinical trials in oncology |
Q37399540 | Ethnic differences and functional analysis of MET mutations in lung cancer |
Q35943089 | Ethnicity affects EGFR and KRAS gene alterations of lung adenocarcinoma |
Q61455095 | Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer |
Q47099044 | Evaluating the Prognostic Value of ERCC1 and Thymidylate Synthase Expression and the Epidermal Growth Factor Receptor Mutation Status in Adenocarcinoma Non-Small-Cell Lung Cancer |
Q37432535 | Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer. |
Q38753542 | Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis |
Q53306420 | Evaluation of PTEN and Mcl-1 expressions in NSCLC expressing wild-type or mutated EGFR. |
Q38686009 | Evaluation of concurrent chemoradiotherapy for locally advanced NSCLC according to EGFR mutation status |
Q51319681 | Evaluation of crizotinib absolute bioavailability, the bioequivalence of three oral formulations, and the effect of food on crizotinib pharmacokinetics in healthy subjects. |
Q41973777 | Evaluation of current methods to detect the mutations of epidermal growth factor receptor in non-small cell lung cancer patients |
Q79346134 | Evaluation of denaturing high-performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in nonsmall-cell lung cancer |
Q33379967 | Evaluation of efficacy and safety of gefitinib as monotherapy in Chinese patients with advanced non-small cell lung cancer and very poor performance status |
Q36611204 | Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA). |
Q36966128 | Evaluation of epidermal growth factor receptor mutations based on mutation specific immunohistochemistry in non-small cell lung cancer: A preliminary study. |
Q40977709 | Evaluation of erlotinib for the treatment of patients with non-small cell lung cancer with epidermal growth factor receptor wild type |
Q51700829 | Evaluation of gefitinib efficacy according to body surface area in patients with non-small cell lung cancer harboring an EGFR mutation. |
Q36523502 | Evaluation of gefitinib for treatment of refractory solid tumors and central nervous system malignancies in pediatric patients |
Q41994944 | Evaluation of immunohistochemistry using two different antibodies and procedures for primary lung adenocarcinoma harboring anaplastic lymphoma kinase rearrangement |
Q39716869 | Evaluation of modified PEG-anilinoquinazoline derivatives as potential agents for EGFR imaging in cancer by small animal PET. |
Q37883964 | Evaluation of molecular prognostic and predictive factors: an important step towards personalised treatment in non small cell lung cancer |
Q36582547 | Evaluation of phosphatidylinositol-3-kinase catalytic subunit (PIK3CA) and epidermal growth factor receptor (EGFR) gene mutations in pancreaticobiliary adenocarcinoma |
Q43846394 | Evaluation of statistical designs in phase I expansion cohorts: the Dana-Farber/Harvard Cancer Center experience. |
Q39308716 | Evaluation of the efficacy and safety of anti-PD-1 and anti-PD-L1 antibody in the treatment of non-small cell lung cancer (NSCLC): a meta-analysis |
Q50674470 | Evaluation of the new IASLC/ATS/ERS proposed classification of adenocarcinoma based on lepidic pattern in patients with pathological stage IA pulmonary adenocarcinoma. |
Q38844092 | Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line. |
Q91729686 | Evolution of Small Molecule Kinase Drugs |
Q47816379 | Evolution of early phase clinical trials in oncology |
Q58613175 | Evolution of platinum resistance in high-grade serous ovarian cancer |
Q33557413 | Evolution of systemic therapy for advanced pancreatic cancer |
Q35591358 | Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer |
Q36327195 | Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy |
Q40228498 | Evolving '-omics' technologies in the drug development process. |
Q30398030 | Evolving health care through personal genomics |
Q34529131 | Evolving landscape of tumor molecular profiling for personalized cancer therapy: a comprehensive review. |
Q37349280 | Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway |
Q83106750 | Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer |
Q37255147 | Existing and emerging technologies for tumor genomic profiling |
Q28743468 | Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines |
Q37416668 | Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte-Duclos disease. |
Q35669012 | Exon 19 deletion of epidermal growth factor receptor is associated with prolonged survival in brain metastases from non-small-cell lung cancer |
Q33621754 | Exons 19 and 21 of epidermal growth factor receptor are highly conserved in squamous cell cancer of the head and neck |
Q43195723 | Expanding options for EGFR targeting in lung cancer |
Q34359274 | Experience with afatinib in patients with non-small cell lung cancer progressing after clinical benefit from gefitinib and erlotinib |
Q38524526 | Experience with erlotinib in the treatment of non-small cell lung cancer |
Q26799390 | Expert Consensus on the Management of Adverse Events from EGFR Tyrosine Kinase Inhibitors in the UK |
Q39288360 | Exploiting Synthetic Lethality and Network Biology to Overcome EGFR Inhibitor Resistance in Lung Cancer. |
Q29615120 | Exploiting the PI3K/AKT pathway for cancer drug discovery |
Q58802587 | Exploiting vulnerabilities in cancer signalling networks to combat targeted therapy resistance |
Q37818230 | Exploration of synthetic lethal interactions as cancer drug targets |
Q41920903 | Exploratory study on the correlation between 14 lung cancer-related gene expression and specific clinical characteristics of NSCLC patients |
Q54319566 | Exploring microRNA-mediated alteration of EGFR signaling pathway in non-small cell lung cancer using an mRNA:miRNA regression model supported by target prediction databases. |
Q52688847 | Expression and copy number gains of the RET gene in 631 early and mid stage non-small cell lung cancer cases. |
Q83855416 | Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma |
Q36341754 | Expression biomarkers for clinical efficacy and outcome prediction in cancer |
Q39144184 | Expression level of CRKL and AXL combined with exon 19 deletion in EGFR and ALK status confer differential prognosis of lung adenocarcinoma subtypes |
Q35218145 | Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer |
Q36774633 | Expression of E-cadherin and KRAS mutation may serve as biomarkers of cetuximab-based therapy in metastatic colorectal cancer |
Q38329982 | Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells |
Q36010179 | Expression of EGFR Is Closely Related to Reduced 3-Year Survival Rate in Chinese Female NSCLC |
Q34745805 | Expression of NRG1 and its receptors in human bladder cancer |
Q40117486 | Expression of Rab5a in hepatocellular carcinoma: Possible involvement in epidermal growth factor signaling |
Q35238466 | Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380 |
Q80587761 | Expression of syndecan-1 and expression of epidermal growth factor receptor are associated with survival in patients with nonsmall cell lung carcinoma |
Q35036471 | Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutations |
Q37457741 | Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma |
Q30009050 | Expression pattern of FGFR2, Grb2 and Plcγ1 acts as a novel prognostic marker of recurrence recurrence-free survival in lung adenocarcinoma |
Q38296583 | Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification |
Q37291399 | FAIM2, as a novel diagnostic maker and a potential therapeutic target for small-cell lung cancer and atypical carcinoid |
Q91982178 | FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC |
Q42059865 | FAM83A and FAM83B: candidate oncogenes and TKI resistance mediators |
Q24296333 | FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice |
Q35073348 | FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma |
Q47307357 | FDA Benefit-Risk Assessment of Osimertinib for the Treatment of Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor T790M Mutation |
Q53089675 | FDG PET/CT metabolic tumor volume and total lesion glycolysis predict prognosis in patients with advanced lung adenocarcinoma. |
Q38234978 | FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC. |
Q39297937 | FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma |
Q38966912 | FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor |
Q36406190 | FGFR1 amplification in squamous cell carcinoma of the lung |
Q47260594 | FLNa negatively regulated proliferation and metastasis in lung adenocarcinoma A549 cells via suppression of EGFR. |
Q36251184 | FLT3 tyrosine kinase inhibitors |
Q40371743 | FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance. |
Q61813957 | FOSB⁻PCDHB13 Axis Disrupts the Microtubule Network in Non-Small Cell Lung Cancer |
Q35745004 | FS-93, an Hsp90 inhibitor, induces G2/M arrest and apoptosis via the degradation of client proteins in oncogene addicted and derived resistant cancer cells |
Q39281214 | Factors associated with efficacy of first-generation epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer |
Q28252845 | Factors underlying sensitivity of cancers to small-molecule kinase inhibitors |
Q39809931 | Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition |
Q35073353 | Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: retrospective and in vitro studies |
Q43101561 | Favorable response to icotinib in a lung cancer patient with a special mutation at exon 19 of epidermal growth factor receptor |
Q36439363 | Feasibility of computed tomography-guided core needle biopsy in producing state-of-the-art clinical management in Chinese lung cancer. |
Q54977963 | Feasibility of continuing crizotinib therapy after RECIST-PD in advanced non-small cell lung cancer patients with ALK/ROS-1 mutations. |
Q37427038 | Feasibility of imaging of epidermal growth factor receptor expression with ZEGFR:2377 affibody molecule labeled with 99mTc using a peptide-based cysteine-containing chelator. |
Q55363718 | Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study. |
Q41729710 | Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain. |
Q37831109 | Feedback regulation of EGFR signalling: decision making by early and delayed loops. |
Q64931081 | Fibrinogen is associated with EGFR mutation status and lymphatic metastasis in non-small cell lung cancer. |
Q24658237 | Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells |
Q90616691 | Fibroblast growth factor receptor 1 gene amplification and protein expression in human lung cancer |
Q36924414 | Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met |
Q37639588 | Final overall survival in JO22903, a phase II, open-label study of first-line erlotinib for Japanese patients with EGFR mutation-positive non-small-cell lung cancer |
Q60918185 | Finding the Right Way to Target EGFR in Glioblastomas; Lessons from Lung Adenocarcinomas |
Q54246031 | Finding the missing links in EGFR. |
Q93382354 | Fine-needle aspiration cytology of non-small cell lung carcinoma: A paradigm shift |
Q60921601 | First- and Second-Generation EGFR-TKIs Are All Replaced to Osimertinib in Chemo-Naive Mutation-Positive Non-Small Cell Lung Cancer? |
Q48004901 | First-Line Carboplatin, Pemetrexed, and Panitumumab in Patients with Advanced Non-Squamous KRAS Wild Type (WT) Non-Small-Cell Lung Cancer (NSCLC). |
Q41569372 | First-line gefitinib for elderly patients with advanced NSCLC harboring EGFR mutations. A combined analysis of North-East Japan Study Group studies |
Q34386915 | First-line gefitinib in Caucasian EGFR mutation-positive NSCLC patients: a phase-IV, open-label, single-arm study. |
Q43639934 | First-line gefitinib therapy for elderly patients with non-small cell lung cancer harboring EGFR mutation: Central Japan Lung Study Group 0901. |
Q47763039 | First-line icotinib versus cisplatin/pemetrexed plus pemetrexed maintenance therapy for patients with advanced EGFR mutation-positive lung adenocarcinoma (CONVINCE): a phase 3, open-label, randomized study |
Q38088215 | First-line management of EGFR-mutated advanced lung adenocarcinoma: recent developments |
Q37625444 | First-line systemic treatment of advanced stage non-small-cell lung cancer in Asia: consensus statement from the Asian Oncology Summit 2009. |
Q38221293 | First-line therapeutic options for advanced non-small-cell lung cancer in the molecular medicine era. |
Q38032437 | First-line therapy of mutated non-small cell lung cancer: an update |
Q54186267 | First-line treatment in NSCLC harboring EGFR common mutations: EGFR TKI in monotherapy or in combination with anti-VEGF? |
Q36283596 | First-line treatment of EGFR-mutant non-small-cell lung cancer: the role of erlotinib and other tyrosine kinase inhibitors |
Q64228070 | First-line tyrosine kinase inhibitors in EGFR mutation-positive non-small-cell lung cancer: a network meta-analysis |
Q34591159 | Five microRNAs in plasma as novel biomarkers for screening of early-stage non-small cell lung cancer |
Q37164590 | Five-Year Survival in EGFR-Mutant Metastatic Lung Adenocarcinoma Treated with EGFR-TKIs |
Q50876305 | Flavonoids and Tannins from Smilax china L. Rhizome Induce Apoptosis Via Mitochondrial Pathway and MDM2-p53 Signaling in Human Lung Adenocarcinoma Cells. |
Q39284284 | Flexible lab-tailored cut-offs for suitability of formalin-fixed tumor samples for diagnostic mutational analyses |
Q55030214 | Flipped script for gefitinib: A reapproved tyrosine kinase inhibitor for first-line treatment of epidermal growth factor receptor mutation positive metastatic nonsmall cell lung cancer. |
Q41965926 | Fluorescent signatures for variable DNA sequences |
Q36939898 | Flying under the radar: the new wave of BCR-ABL inhibitors |
Q28550689 | Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer |
Q38089600 | Focus on the potential role of ficlatuzumab in the treatment of non-small cell lung cancer |
Q35845580 | Focused molecular analysis of small cell lung cancer: feasibility in routine clinical practice |
Q42368437 | Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation |
Q35200424 | Following the crumbs: from tissue samples, to pharmacogenomics, to NSCLC therapy |
Q34669260 | Fool's gold, lost treasures, and the randomized clinical trial |
Q39528185 | Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks |
Q83230378 | Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4 |
Q37698293 | Four-dimensional dynamics of MAPK information processing systems. |
Q40929491 | Frequencies of EGFR single nucleotide polymorphisms in non-small cell lung cancer patients and healthy individuals in the Republic of Serbia: a preliminary study |
Q92798844 | Frequency and clinical features of BRAF mutations among patients with stage III/IV lung adenocarcinoma without EGFR/ALK aberrations |
Q27851448 | Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma |
Q34673282 | Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer |
Q35915133 | Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans |
Q37110396 | Frequency of EGFR and KRAS mutations in patients with non small cell lung cancer by racial background: do disparities exist? |
Q35016912 | Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity |
Q35871742 | Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histologic subtypes and age at diagnosis |
Q46607446 | Frequency of epidermal growth factor receptor mutations in Bangladeshi patients with adenocarcinoma of the lung |
Q54284515 | Frequent alterations of HER2 through mutation, amplification, or overexpression in pleomorphic lobular carcinoma of the breast. |
Q27851615 | Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. |
Q38489488 | Frequent central nervous system failure after clinical benefit with epidermal growth factor receptor tyrosine kinase inhibitors in Korean patients with nonsmall-cell lung cancer. |
Q46738962 | Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung |
Q80173694 | From bench to bedside and back again? |
Q28533949 | From bench to bedside: lessons learned in translating preclinical studies in cancer drug development |
Q50123361 | From biology to therapy: Improvements of therapeutic options in Lung cancer. |
Q24621007 | From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway |
Q92302884 | From discovery of tyrosine phosphorylation to targeted cancer therapies: The 2018 Tang Prize in Biopharmaceutical Science |
Q37551148 | From drug discovery to biomarker-driven clinical trials in lymphoma |
Q37003218 | From genotype to phenotype: Are there imaging characteristics associated with lung adenocarcinomas harboring RET and ROS1 rearrangements? |
Q26830811 | From modules to medicine: How modular domains and their associated networks can enable personalized medicine |
Q55093479 | From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo. |
Q46560311 | From nihilism to individualism: the evolution of lung cancer therapy |
Q37236447 | From oncogene to network addiction: the new frontier of cancer genomics and therapeutics |
Q28385559 | From single-gene to multiplex analysis in lung cancer, challenges and accomplishments: a review of a single institution's experience |
Q35117568 | From the bench to bedside: biological and methodology considerations for the future of companion diagnostics in nonsmall cell lung cancer |
Q26864637 | From tissue to molecular phenotyping: pre-analytical requirements heidelberg experience |
Q90612116 | Frontiers of ctDNA, targeted therapies, and immunotherapy in non-small-cell lung cancer |
Q34094224 | Frontline gefitinib in advanced non-small cell lung cancer: Meta-analysis of published randomized trials |
Q93337424 | Fully automated real-time PCR for EGFR testing in non-small cell lung carcinoma |
Q36120023 | Functional analysis of cancer-associated EGFR mutants using a cellular assay with YFP-tagged EGFR intracellular domain |
Q37732019 | Functional analysis of polymorphisms in the COX-2 gene and risk of lung cancer |
Q36221780 | Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. |
Q51739953 | Functional characterization of an activating TEK mutation in acute myeloid leukemia: a cellular context-dependent activating mutation. |
Q33838325 | Functional characterization of human cancer-derived TRKB mutations |
Q34423170 | Functional consequences of somatic mutations in cancer using protein pocket-based prioritization approach |
Q54977360 | Functional cooperation between HIF-1α and c-Jun in mediating primary and acquired resistance to gefitinib in NSCLC cells with activating mutation of EGFR. |
Q33368629 | Functional copy-number alterations in cancer |
Q37999073 | Functional drug-gene interactions in lung cancer. |
Q45933675 | Functional evaluation of therapeutic response of HCC827 lung cancer to bevacizumab and erlotinib targeted therapy using dynamic contrast-enhanced and diffusion-weighted MRI. |
Q85001306 | Functional mutation analysis of EGFR family genes and corresponding lymph node metastases in head and neck squamous cell carcinoma |
Q48013156 | Functional precision cancer medicine-moving beyond pure genomics |
Q37269270 | Functional role of eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) in NSCLC |
Q36895812 | Future of molecular profiling of human hepatocellular carcinoma |
Q35404376 | Fuzheng Kang'ai decoction combined with gefitinib in advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: study protocol for a randomized controlled trial |
Q42702662 | GAB2 Amplification in Squamous Cell Lung Cancer of Non-Smokers. |
Q49789981 | GRK5 functions as an oncogenic factor in non-small-cell lung cancer. |
Q61804215 | GSK-3β regulates the endothelial-to-mesenchymal transition via reciprocal crosstalk between NSCLC cells and HUVECs in multicellular tumor spheroid models |
Q55070732 | Gain of copy number and amplification of the RET gene in lung cancer. |
Q35067654 | Galectin-4, a novel predictor for lymph node metastasis in lung adenocarcinoma |
Q40161268 | Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib |
Q34768400 | Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells |
Q54719163 | Gastrointestinal toxicities of novel agents in cancer therapy. |
Q33265628 | Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation |
Q39400141 | Gefitinib (ZD1839) increases the efficacy of cisplatin in ovarian cancer cells |
Q36135604 | Gefitinib (ZD1839, Iressa) in non-small-cell lung cancer: a review of clinical trials from a daily practice perspective. |
Q64969430 | Gefitinib Plus Bevacizumab vs. Gefitinib Alone for EGFR Mutant Non-squamous Non-small Cell Lung Cancer. |
Q28485309 | Gefitinib analogue V1801 induces apoptosis of T790M EGFR-harboring lung cancer cells by up-regulation of the BH-3 only protein Noxa |
Q54564062 | Gefitinib and chemotherapy combination studies in five novel human non small cell lung cancer xenografts. Evidence linking EGFR signaling to gefitinib antitumor response. |
Q35345489 | Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials. |
Q36740873 | Gefitinib as first line therapy in Malaysian patients with EGFR mutation-positive non-small-cell lung cancer: A single-center retrospective study |
Q46333966 | Gefitinib first or gefitinib second: is timing everything in the treatment of EGFR mutant non-small cell lung cancer? |
Q36612517 | Gefitinib for non-small-cell lung cancer patients with epidermal growth factor receptor gene mutations screened by peptide nucleic acid-locked nucleic acid PCR clamp |
Q37929795 | Gefitinib for non-small-cell lung cancer treatment |
Q88123698 | Gefitinib for oesophageal cancer: a cog in need of a wheel? |
Q37357287 | Gefitinib for the treatment of non-small-cell lung cancer |
Q37738913 | Gefitinib for the treatment of non-small-cell lung cancer. |
Q36512046 | Gefitinib in Selected Patients with Pre-Treated Non-Small-Cell Lung Cancer: Results from a Phase IV, Multicenter, Non-Randomized Study (SELINE) |
Q35031807 | Gefitinib in non small cell lung cancer |
Q36161284 | Gefitinib in non-small cell lung cancer |
Q36610166 | Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). |
Q37449013 | Gefitinib in the treatment of advanced non-small-cell lung cancer |
Q26739096 | Gefitinib in the treatment of nonsmall cell lung cancer with activating epidermal growth factor receptor mutation |
Q54321696 | Gefitinib induces cytoplasmic translocation of the CDK inhibitor p27 and its binding to a cleaved intermediate of caspase 8 in non-small cell lung cancer cells. |
Q28534577 | Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification |
Q36155335 | Gefitinib is more effective in never-smokers with non-small-cell lung cancer: experience among Asian patients |
Q50506376 | Gefitinib plus Fuzheng Kang'ai Formula () in patients with advanced non-small cell lung cancer with epidermal growth factor receptor mutation: A randomized controlled trial. |
Q29620605 | Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer) |
Q36065216 | Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity |
Q34114278 | Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated |
Q33231452 | Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation |
Q36615832 | Gefitinib treatment affects androgen levels in non-small-cell lung cancer patients |
Q53513542 | Gefitinib treatment in patients with postoperative recurrent non-small-cell lung cancer harboring epidermal growth factor receptor gene mutations. |
Q44679030 | Gefitinib treatment is highly effective in non-small-cell lung cancer patients failing previous chemotherapy in Taiwan: a prospective phase II study |
Q29619975 | Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial |
Q46232500 | Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. |
Q30544631 | Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study |
Q42328764 | Gefitinib with pemetrexed as first-line therapy in patients with advanced nonsquamous non-small cell lung cancer with activating epidermal growth factor receptor mutations |
Q37419104 | Gefitinib, Fluorouracil, Oxaliplatin, and Leucovorin (IFOX) Regimen for Colorectal Cancer |
Q45169148 | Gefitinib--a novel targeted approach to treating cancer |
Q28469345 | Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics |
Q35580846 | Gefitinib-mediated reactive oxygen specie (ROS) instigates mitochondrial dysfunction and drug resistance in lung cancer cells |
Q36661222 | Gefitinib-resistance is related to BIM expression in non-small cell lung cancer cell lines |
Q43042819 | Gefitinib: a consideration of cost |
Q38338492 | Gefitinib: a review of its use in adults with advanced non-small cell lung cancer |
Q33207883 | Gefitinib: a review of its use in the management of advanced non-small-cell lung cancer |
Q33915997 | Gemcitabine for the treatment of advanced nonsmall cell lung cancer |
Q64238805 | Gene Expression Profiling Reveals Distinct Molecular Subtypes of Esophageal Squamous Cell Carcinoma in Asian Populations |
Q37221902 | Gene Expression of the EGF System-a Prognostic Model in Non-Small Cell Lung Cancer Patients Without Activating EGFR Mutations |
Q94603193 | Gene Signature for Sorafenib Susceptibility in Hepatocellular Carcinoma: Different Approach with a Predictive Biomarker |
Q36755676 | Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma |
Q83139511 | Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma |
Q46465639 | Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study |
Q41714879 | Gene copy number gain of EGFR is a poor prognostic biomarker in gastric cancer: evaluation of 855 patients with bright-field dual in situ hybridization (DISH) method |
Q38378815 | Gene expression of MAGE-A3 and PRAME tumor antigens and EGFR mutational status in Taiwanese non-small cell lung cancer patients |
Q33263277 | Gene expression patterns that predict sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer cell lines and human lung tumors |
Q40141195 | Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma |
Q39312152 | Gene expression-based chemical genomics identifies heat-shock protein 90 inhibitors as potential therapeutic drugs in cholangiocarcinoma. |
Q24809183 | Gene mutations in lung cancer: promising predictive factors for the success of molecular therapy |
Q34994030 | Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer |
Q39159155 | Gene silencing of c-Met leads to brain metastasis inhibitory effects |
Q28397345 | Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies |
Q34566773 | Gene-guided gefitinib switch maintenance therapy for patients with advanced EGFR mutation-positive non-small cell lung cancer: an economic analysis |
Q33829488 | Generation of lung cancer cell lines harboring EGFR T790M mutation by CRISPR/Cas9-mediated genome editing |
Q54114243 | Genetic Association of Drug Response to Erlotinib in Chinese Advanced Non-small Cell Lung Cancer Patients. |
Q38198930 | Genetic Interactions of STAT3 and Anticancer Drug Development |
Q40498334 | Genetic Modifiers of Progression-Free Survival in Never-Smoking Lung Adenocarcinoma Patients Treated with First-Line Tyrosine Kinase Inhibitors |
Q35898597 | Genetic abnormalities of the EGFR pathway in African American Patients with non-small-cell lung cancer |
Q36695240 | Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma |
Q36524569 | Genetic alterations in lung adenocarcinoma with a micropapillary component |
Q40040928 | Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines |
Q36393012 | Genetic alterations in urothelial bladder carcinoma: an updated review |
Q34674319 | Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer |
Q34125003 | Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance |
Q33520794 | Genetic and proteomic features associated with survival after treatment with erlotinib in first-line therapy of non-small cell lung cancer in Eastern Cooperative Oncology Group 3503. |
Q36115735 | Genetic changes in squamous cell lung cancer: a review |
Q37899883 | Genetic determinants of anticancer drug activity: towards a global approach to personalized cancer medicine. |
Q35897344 | Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma |
Q37977835 | Genetic insight and therapeutic targets in squamous-cell lung cancer |
Q34832117 | Genetic modifiers of EGFR dependence in non-small cell lung cancer |
Q37113682 | Genetic predictors of MEK dependence in non-small cell lung cancer |
Q34658903 | Genetic variations of the A13/A14 repeat located within the EGFR 3' untranslated region have no oncogenic effect in patients with colorectal cancer |
Q33693846 | Genetic-based prediction of disease traits: prediction is very difficult, especially about the future |
Q37765099 | Genetics of biliary tract cancers and emerging targeted therapies |
Q36344243 | Genetics of drug resistance |
Q39872383 | Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines |
Q28391355 | Genome stability pathways in head and neck cancers |
Q28385454 | Genome wide SNP comparative analysis between EGFR and KRAS mutated NSCLC and characterization of two models of oncogenic cooperation in non-small cell lung carcinoma |
Q33598001 | Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer |
Q37037246 | Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers |
Q34354428 | Genome-wide identification of significant aberrations in cancer genome. |
Q82452891 | Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway |
Q37028708 | Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets |
Q35671373 | Genomic Characterization of Non-Small-Cell Lung Cancer in African Americans by Targeted Massively Parallel Sequencing |
Q92555522 | Genomic Medicine-Progress, Pitfalls, and Promise |
Q55457466 | Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations. |
Q33313648 | Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers |
Q49678076 | Genomic alterations of ERBB receptors in cancer: clinical implications. |
Q37427132 | Genomic amplification and high expression of EGFR are key targetable oncogenic events in malignant peripheral nerve sheath tumor |
Q35079683 | Genomic analyses across six cancer types identify basal-like breast cancer as a unique molecular entity |
Q36195093 | Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer |
Q35873554 | Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer |
Q34104493 | Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors |
Q35036588 | Genomic and transcriptional alterations in lung adenocarcinoma in relation to EGFR and KRAS mutation status |
Q38060203 | Genomic biomarkers for patient selection and stratification: the cancer paradigm. |
Q36851245 | Genomic landscape of non-small cell lung cancer in smokers and never-smokers |
Q38231825 | Genomic medicine and targeted therapy for solid tumors |
Q38114005 | Genomic medicine: a decade of successes, challenges, and opportunities |
Q37269251 | Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative |
Q36207381 | Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response |
Q26853507 | Genomic sequencing in cancer |
Q35807322 | Genomic technology applied to pharmacological traits |
Q35252277 | Genomics and drug response |
Q36084693 | Genomics of lung cancer may change diagnosis, prognosis and therapy |
Q92830555 | Genomics-Enabled Precision Medicine for Cancer |
Q37376509 | Genomics: applications in mechanism elucidation |
Q35519172 | Genotype-dependent sensitivity of uveal melanoma cell lines to inhibition of B-Raf, MEK, and Akt kinases: rationale for personalized therapy |
Q35146927 | Genotype-driven therapies for non-small cell lung cancer: focus on EGFR, KRAS and ALK gene abnormalities |
Q27851633 | Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors |
Q36660664 | Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies |
Q33275318 | Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1 |
Q33901617 | Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: a novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma |
Q35546231 | Germline EGFR T790M mutation found in multiple members of a familial cohort |
Q40732783 | Germline mutations causing familial lung cancer |
Q33367793 | Germline polymorphisms as modulators of cancer phenotypes |
Q94481864 | Germline whole exome sequencing of a family with appendiceal mucinous tumours presenting with pseudomyxoma peritonei |
Q40116157 | Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity. |
Q38460865 | Glioblastoma: pathology, molecular mechanisms and markers |
Q35089063 | Global Oct4 target gene analysis reveals novel downstream PTEN and TNC genes required for drug-resistance and metastasis in lung cancer |
Q37699154 | Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer |
Q30447539 | Gold nanoparticles: From nanomedicine to nanosensing. |
Q34059536 | Good Clinical Response to Erlotinib in a Non-Small Cell Lung Cancer Patient Harboring Multiple Brain Metastases and a Double Active Somatic Epidermal Growth Factor Gene Mutation |
Q27851566 | Good clinical response to gefitinib in a non-small cell lung cancer patient harboring a rare somatic epidermal growth factor gene point mutation; codon 768 AGC > ATC in exon 20 (S768I). |
Q90429716 | Gossypol Inhibits Non-small Cell Lung Cancer Cells Proliferation by Targeting EGFRL858R/T790M |
Q42035610 | Grand challenge commentary: Informative diagnostics for personalized medicine. |
Q46939852 | Griffipavixanthone from Garcinia oblongifolia champ induces cell apoptosis in human non-small-cell lung cancer H520 cells in vitro |
Q49287962 | Ground-glass opacity heralding invasive lung adenocarcinoma with prodromal dermatomyositis: a case report. |
Q37045217 | Growth factors and oncogenes as targets in melanoma: lost in translation? |
Q34064620 | Growth suppression of lung cancer cells by targeting cyclic AMP response element-binding protein |
Q37631021 | Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group. |
Q39622232 | Guidelines for biomarker testing in advanced non-small-cell lung cancer. A national consensus of the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP). |
Q90448494 | HCC-derived EGFR mutants are functioning, EGF-dependent, and erlotinib-resistant |
Q37073441 | HER Receptor Family: Novel Candidate for Targeted Therapy for Gallbladder and Extrahepatic Bile Duct Cancer |
Q36734936 | HER family inhibitors in pancreatic cancer: current status and future directions |
Q33699007 | HER kinase axis receptor dimer partner switching occurs in response to EGFR tyrosine kinase inhibition despite failure to block cellular proliferation |
Q36217582 | HER1/EGFR tyrosine kinase inhibitors for the treatment of glioblastoma multiforme |
Q36061145 | HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy. |
Q36322762 | HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation |
Q41308137 | HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer |
Q55045037 | HER3 expression is enhanced during progression of lung adenocarcinoma without EGFR mutation from stage 0 to IA1. |
Q36615002 | HER3 genomic gain and sensitivity to gefitinib in advanced non-small-cell lung cancer patients |
Q39263953 | HGF induces novel EGFR functions involved in resistance formation to tyrosine kinase inhibitors |
Q36822204 | HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer |
Q33586269 | HPV infection and EGFR activation/alteration in HIV-infected East African patients with conjunctival carcinoma |
Q52717015 | Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents. |
Q54257595 | Harnessing massively parallel DNA sequencing for the personalization of cancer management. |
Q37411128 | Harnessing plasma genotyping for precision therapy against lung cancer |
Q89634774 | Harnessing the vulnerabilities of p53 mutants in lung cancer - Focusing on the proteasome: a new trick for an old foe? |
Q36249234 | Have we made progress in pharmacogenomics? The implementation of molecular markers in colon cancer |
Q58197295 | Head and neck cancer: from research to therapy and cure |
Q35762499 | Heat shock protein 90 inhibition in lung cancer |
Q38819110 | Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers |
Q46268586 | Hemorrhagic pericardial effusion and multiple pulmonary nodules in a 37 year old male who has "never smoked" |
Q42995833 | Heparin-binding EGF-like factor augments esophageal epithelial cell proliferation, migration and inhibits TRAIL-mediated apoptosis via EGFR/MAPK signaling. |
Q38377273 | Hepatocyte growth factor and Met in drug discovery |
Q36842715 | Her signaling in pancreatic cancer |
Q33747967 | Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system |
Q92163099 | Heregulin expression and its clinical implication for patients with EGFR-mutant non-small cell lung cancer treated with EGFR-tyrosine kinase inhibitors |
Q27853391 | Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma |
Q38065082 | Heterogeneity of the EGFR mutation status between the primary tumor and metastatic lymph node and the sensitivity to EGFR tyrosine kinase inhibitor in non-small cell lung cancer |
Q42227138 | Heterozygous mutation (G/G→G/A) at nt 2607 of the EGFR gene is closely associated with increases in EGFR copy number and mRNA half life, but impaired EGFR protein synthesis in squamous cell carcinomas of the head and neck - implication for gefitinib |
Q30157152 | Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations |
Q36793862 | High EGFR copy number predicts benefits from tyrosine kinase inhibitor treatment for non-small cell lung cancer patients with wild-type EGFR. |
Q53300836 | High EGFR gene copy number predicts poor outcome in triple-negative breast cancer. |
Q36051484 | High ERK protein expression levels correlate with shorter survival in triple-negative breast cancer patients |
Q41708722 | High PHLPP1 expression levels predicts longer time of acquired resistance to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma |
Q38776722 | High expression of EGFR predicts poor survival in patients with resected T3 stage gastric adenocarcinoma and promotes cancer cell survival |
Q28304785 | High frequency of BRAF V600E mutations in ameloblastoma |
Q46448637 | High incidence of disease recurrence in the brain and leptomeninges in patients with nonsmall cell lung carcinoma after response to gefitinib |
Q33717222 | High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886) |
Q25257525 | High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization |
Q33336861 | High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies |
Q33267389 | High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer. |
Q37619902 | High sensitivity EndoV mutation scanning through real-time ligase proofreading |
Q40822344 | High serum level of C-reactive protein is associated with worse outcome of patients with advanced-stage NSCLC treated with erlotinib. |
Q87745890 | High specificity but low sensitivity of mutation-specific antibodies against EGFR mutations in non-small-cell lung cancer |
Q28740553 | High throughput interrogation of somatic mutations in high grade serous cancer of the ovary |
Q37109744 | High-content analysis of cancer genome DNA alterations |
Q36477716 | High-fidelity of non-small cell lung cancer xenograft models derived from bronchoscopy-guided biopsies |
Q38754469 | High-throughput Phenotyping of Lung Cancer Somatic Mutations |
Q45901707 | High-throughput biochemical kinase selectivity assays: panel development and screening applications. |
Q34050186 | High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes |
Q39991911 | High-throughput lung cancer cell line screening for genotype-correlated sensitivity to an EGFR kinase inhibitor |
Q36288148 | High-throughput molecular analysis in lung cancer: insights into biology and potential clinical applications |
Q36497083 | High-throughput mutational analysis of the human cancer genome |
Q57693480 | High-throughput oncogene mutation profiling in human cancer |
Q42316845 | High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients |
Q36591388 | High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia |
Q40476723 | Highly Sensitive and Reliable Detection of EGFR Exon 19 Deletions by Droplet Digital Polymerase Chain Reaction. |
Q27851714 | Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer |
Q37068513 | Highly parallel identification of essential genes in cancer cells |
Q50465588 | Highly sensitive EGFR mutation detection by specific amplification of mutant alleles. |
Q38164052 | Histo-cytological diagnostic accuracy in lung cancer |
Q48132127 | Histologic Grade Is Predictive of Incidence of Epidermal Growth Factor Receptor Mutations in Metastatic Lung Adenocarcinoma |
Q40109306 | Histological Transformation to Large Cell Neuroendocrine Carcinoma from Lung Adenocarcinoma Harboring an EGFR Mutation: An Autopsy Case Report. |
Q33904760 | Histological comparison between preoperative and surgical specimens of non-small cell lung cancer for distinguishing between "squamous" and "non-squamous" cell carcinoma |
Q48150376 | Histone Deacetylase Inhibitors Resensitize EGFR/EGFRvIII-Overexpressing, Erlotinib-Resistant Glioblastoma Cells to Tyrosine Kinase Inhibition. |
Q37598057 | Historical Evolution of Second-Line Therapy in Non-Small Cell Lung Cancer |
Q42292319 | Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells |
Q38858961 | Honokiol targets mitochondria to halt cancer progression and metastasis |
Q95260313 | Hormone receptor expression correlates with EGFR gene mutation in lung cancer in patients with simultaneous primary breast cancer |
Q37793837 | How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine |
Q37245907 | How Molecular Understanding Affects to Prescribing Patterns and Clinical Outcome of Gefitinib in Non-small Cell Lung Cancer? 10 Year Experience of Single Institution |
Q37588365 | How and when to use genetic markers for nonsmall cell lung cancer. |
Q37065678 | How genetically engineered mouse tumor models provide insights into human cancers |
Q26992045 | How many molecular subtypes? Implications of the unique tumor principle in personalized medicine |
Q48411592 | How to develop novel treatments for EGFR-mutant lung cancer. |
Q37587294 | How to unleash mitochondrial apoptotic blockades to kill cancers? |
Q36429550 | How will lung cancer be treated in the future? |
Q40352167 | Hsp90 inhibitors cause G2/M arrest associated with the reduction of Cdc25C and Cdc2 in lung cancer cell lines |
Q36982771 | Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines |
Q27023576 | Human correlates of provocative questions in pancreatic pathology |
Q37538406 | Humoral immune responses to EGFR-derived peptides predict progression-free and overall survival of non-small cell lung cancer patients receiving gefitinib |
Q52655439 | Hybrid Capture-Based Comprehensive Genomic Profiling Identifies Lung Cancer Patients with Well-Characterized Sensitizing Epidermal Growth Factor Receptor Point Mutations That Were Not Detected by Standard of Care Testing. |
Q37379240 | Hydrogel-based protein array for quantifying epidermal growth factor receptor activity in cell lysates |
Q60050105 | Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells |
Q35591083 | Hypermethylated Epidermal growth factor receptor (EGFR) promoter is associated with gastric cancer |
Q89206292 | Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1 |
Q40147314 | Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway |
Q39302684 | Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors. |
Q38968478 | Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition. |
Q38659248 | ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection |
Q35631086 | IGDB.NSCLC: integrated genomic database of non-small cell lung cancer |
Q39101764 | IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations |
Q35833023 | IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer. |
Q37520432 | IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib |
Q47773490 | Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial |
Q38666574 | Icotinib versus whole-brain irradiation in patients with EGFR-mutant non-small-cell lung cancer and multiple brain metastases (BRAIN): a multicentre, phase 3, open-label, parallel, randomised controlled trial |
Q38352862 | Icotinib, a selective EGF receptor tyrosine kinase inhibitor, for the treatment of non-small-cell lung cancer |
Q36843769 | Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells |
Q79448974 | Identical epidermal growth factor receptor mutations in adenocarcinomatous and squamous cell carcinomatous components of adenosquamous carcinoma of the lung |
Q38668707 | Identification and Validation of Driver Kinases from Next-Generation Sequencing Data |
Q36557174 | Identification and characterization of RET fusions in advanced colorectal cancer |
Q30877356 | Identification and preliminary characterization of novel small molecules that inhibit growth of human lung adenocarcinoma cells |
Q24633776 | Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach |
Q42646980 | Identification of 10 Candidate Biomarkers Distinguishing Tuberculous and Malignant Pleural Fluid by Proteomic Methods. |
Q34354515 | Identification of 33 candidate oncogenes by screening for base-specific mutations. |
Q98384563 | Identification of 4-Anilino-6-aminoquinazoline Derivatives as Potential MERS-CoV Inhibitors |
Q47100541 | Identification of Clinically Approved Drugs Indacaterol and Canagliflozin for Repurposing to Treat Epidermal Growth Factor Tyrosine Kinase Inhibitor-Resistant Lung Cancer |
Q92350228 | Identification of Crucial Candidate Genes and Pathways in Glioblastoma Multiform by Bioinformatics Analysis |
Q46393465 | Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy |
Q54268313 | Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma. |
Q92102263 | Identification of Epidermal Growth Factor Receptor Tyrosine-Kinase Mutations in Non-small Cell Lung Cancer: Testing Platform Matters |
Q91844098 | Identification of FOS as a Candidate Risk Gene for Liver Cancer by Integrated Bioinformatic Analysis |
Q43161186 | Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers |
Q41637034 | Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma |
Q39167915 | Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo |
Q51326919 | Identification of a new insertion in exon 20 of EGFR in a woman with NSCLC. |
Q34887667 | Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity |
Q61815055 | Identification of antiproliferative emodin analogues as inhibitors of epidermal growth factor receptor in cancer |
Q28239452 | Identification of cancer genes by mutational profiling of tumor genomes |
Q45030586 | Identification of driver mutations in lung cancer: first step in personalized cancer |
Q54457108 | Identification of epidermal growth factor receptor (EGFR) exon 20 single nucleotide polymorphism in Chinese squamous cell carcinoma of head and neck (SCCHN). |
Q37368954 | Identification of exon 19 and 21 mutations of EGFR gene in Chinese patients with esophageal squamous cell carcinoma |
Q31132212 | Identification of gefitinib off-targets using a structure-based systems biology approach; their validation with reverse docking and retrospective data mining |
Q41623567 | Identification of microRNAs involved in gefitinib resistance of non-small-cell lung cancer through the insulin-like growth factor receptor 1 signaling pathway |
Q37323468 | Identification of molecular targets in urologic oncology |
Q33690276 | Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients |
Q64105070 | Identification of novel mutations of Insulin Receptor Substrate 1 (IRS1) in tumor samples of non-small cell lung cancer (NSCLC): Implications for aberrant insulin signaling in development of cancer |
Q35166315 | Identification of oncogenic point mutations and hyperphosphorylation of anaplastic lymphoma kinase in lung cancer. |
Q91793139 | Identification of somatic copy number variations in plasma cell free DNA correlating with intrinsic resistances to EGFR targeted therapy in T790M negative non-small cell lung cancer |
Q36897470 | Identification of structural aberrations in cancer by SNP array analysis |
Q46557776 | Identification of the rare EGFR mutation p.G796S as somatic and germline mutation in white patients with squamous cell carcinoma of the head and neck |
Q28511622 | Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification |
Q27851410 | Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer |
Q36127636 | Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamics |
Q91742348 | Identifying a wide range of actionable variants using capture-based ultra-deep targeted sequencing in treatment-naive patients with primary lung adenocarcinoma |
Q26781810 | Identifying activating mutations in the EGFR gene: prognostic and therapeutic implications in non-small cell lung cancer |
Q34295696 | Identifying and targeting ROS1 gene fusions in non-small cell lung cancer |
Q90610221 | Identifying epidermal growth factor receptor mutation status in patients with lung adenocarcinoma by three-dimensional convolutional neural networks |
Q35264584 | Identifying erlotinib-sensitive non-small cell lung carcinoma tumors in mice using [(11)C]erlotinib PET. |
Q36328508 | Identifying molecular markers for the early detection of pancreatic neoplasia |
Q38420747 | Identifying novel targets of oncogenic EGF receptor signaling in lung cancer through global phosphoproteomics. |
Q89926672 | Identifying relationships between imaging phenotypes and lung cancer-related mutation status: EGFR and KRAS |
Q37889967 | Identifying responders to trastuzumab therapy in breast cancer |
Q55401345 | Identifying the Causes of Cancer Health Disparities: Biologic and Non Biologic Determinants. |
Q37187172 | Imaging Characteristics in ALK Fusion-Positive Lung Adenocarcinomas by Using HRCT. |
Q38137829 | Imaging EGFR and HER2 by PET and SPECT: a review |
Q38852701 | Imaging in Advanced Non-Small Cell Lung Cancer: A Medical Oncology Perspective. |
Q37320501 | Imaging of EGFR and EGFR tyrosine kinase overexpression in tumors by nuclear medicine modalities. |
Q36050371 | Imaging of lung cancer in the era of molecular medicine |
Q36654677 | Immediate Versus Delayed Treatment with EGFR Tyrosine Kinase Inhibitors after First-line Therapy in Advanced Non-small-cell Lung CANCER |
Q38206386 | Immune regulation of therapy-resistant niches: emerging targets for improving anticancer drug responses |
Q37898427 | Immunochemistry and lung cancer: application in diagnosis, prognosis and targeted therapy |
Q38868664 | Immunohistochemical analysis of EGFR and hyaluronan in tongue cancer and the development of regional recurrence in patients initially diagnosed N0. |
Q54399363 | Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers. |
Q34008820 | Immunohistochemical expression of epidermal growth factor receptor (EGFR) in oral squamous cell carcinoma in relation to proliferation, apoptosis, angiogenesis and lymphangiogenesis |
Q34158993 | Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma |
Q47140225 | Immunohistochemistry for predictive biomarkers in non-small cell lung cancer |
Q51046274 | Immunohistochemistry with a novel mutation-specific monoclonal antibody as a screening tool for the EGFR L858R mutational status in primary lung adenocarcinoma. |
Q57069991 | Immunotherapy combined with epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer treatment |
Q38367414 | Immunotherapy for lung cancer: for whom the bell tolls? |
Q51132444 | Immunotherapy in lung cancer. |
Q55312983 | Immunotherapy in the Asiatic population: any differences from Caucasian population? |
Q52624361 | Immunotherapy in treatment naïve advanced non-small cell lung cancer. |
Q36797398 | Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18. |
Q26751473 | Immunotoxin Therapies for the Treatment of Epidermal Growth Factor Receptor-Dependent Cancers |
Q47654457 | Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma. |
Q39957730 | Impact of EGFR gene polymorphisms on anticancer drug cytotoxicity in vitro |
Q34339890 | Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis |
Q38937520 | Impact of EGFR mutations and KRAS amino acid substitution on the response to radiotherapy for brain metastasis of non-small-cell lung cancer. |
Q50853655 | Impact of EGFR tyrosine kinase inhibitors versus chemotherapy on the development of leptomeningeal metastasis in never smokers with advanced adenocarcinoma of the lung. |
Q34028470 | Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib |
Q35852269 | Impact of Pre-Analytical Variables on Cancer Targeted Gene Sequencing Efficiency. |
Q36534696 | Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials |
Q42949033 | Impact of Serum Hepatocyte Growth Factor on Treatment Response to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients with Non–Small Cell Lung Adenocarcinoma |
Q50321656 | Impact of Weight Loss at Presentation on Survival in Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors (EGFR-TKI) Sensitive Mutant Advanced Non-small Cell Lung Cancer (NSCLC) Treated with First-line EGFR-TKI. |
Q37471822 | Impact of active smoking on survival of patients with metastatic lung adenocarcinoma harboring an epidermal growth factor receptor (EGFR) mutation |
Q92646422 | Impact of age on EGFR mutations in never-smoking female lung adenocarcinoma patients with malignant pleural effusion |
Q37742492 | Impact of biomarkers on non-small cell lung cancer treatment |
Q40876078 | Impact of body surface area on survival in EGFR-mutant non-small cell lung cancer patients treated with gefitinib monotherapy: observational study of the Okayama Lung Cancer Study Group 0703. |
Q97538360 | Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer |
Q41612456 | Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians |
Q42167271 | Impact of epidermal growth factor receptor (EGFR) kinase mutations, EGFR gene amplifications, and KRAS mutations on survival of pancreatic adenocarcinoma |
Q24625201 | Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials |
Q53597217 | Impact of genetic diagnostics on drug development strategy. |
Q80845931 | Impact of genetic polymorphisms in DNA repair enzymes on drug resistance in lung cancer |
Q89543321 | Impact of somatic mutations on prognosis in resected non-small-cell lung cancer: The Japan Molecular Epidemiology for lung cancer study |
Q85515558 | Impact of the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification of stage IA adenocarcinoma of the lung: Correlation between computed tomography images and EGFR and KRAS gene |
Q41879278 | Impact of thymidylate synthase protein expression on efficacy of chemotherapy in advanced lung cancer patients |
Q92334155 | Impact of tumor microenvironment on the efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with EGFR-mutant non-small cell lung cancer |
Q35560129 | Impact of upfront cellular enrichment by laser capture microdissection on protein and phosphoprotein drug target signaling activation measurements in human lung cancer: Implications for personalized medicine. |
Q62512297 | Impact ofABCG2polymorphisms on the clinical outcome and toxicity of gefitinib in non-small-cell lung cancer patients |
Q37186795 | Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations |
Q39712642 | Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations |
Q39045171 | Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes. |
Q34163458 | Implementation of biomarker-driven cancer therapy: existing tools and remaining gaps |
Q37005953 | Implementation of genetics to personalize medicine |
Q38320914 | Implementation of modern therapy approaches and research for non-small cell lung cancer in Japan |
Q36383418 | Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice |
Q34404229 | Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts |
Q37118974 | Implications of EGFR PharmDx kit for cetuximab eligibility |
Q26764917 | Implications of MicroRNAs in the Treatment of Gefitinib-Resistant Non-Small Cell Lung Cancer |
Q37678306 | Implications of key trials in advanced nonsmall cell lung cancer |
Q98386333 | Implications of lipid droplets in lung cancer: Associations with drug resistance |
Q83508020 | Implications of personalized medicine--perspective from a cancer center |
Q34838412 | Importance of molecular features of non-small cell lung cancer for choice of treatment |
Q38067427 | Importance of the cytological samples for the epidermal growth factor receptor gene mutation test for non-small cell lung cancer |
Q38389841 | Improving Clinical Trial Efficiency: Thinking outside the Box. |
Q42545098 | Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors |
Q42036423 | Improving clinical trial efficiency by biomarker-guided patient selection |
Q51281967 | In Vitro Enzyme Kinetics Analysis of EGFR. |
Q42758535 | In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma |
Q35905204 | In silico analysis of the effect of mutation on epidermal growth factor receptor in non-small-cell lung carcinoma: from mutational analysis to drug designing |
Q47355906 | In silico evaluation of the resistance of the T790M variant of epidermal growth factor receptor kinase to cancer drug Erlotinib. |
Q54578263 | In silico screening of epidermal growth factor receptor (EGFR) in the tyrosine kinase domain through a medicinal plant compound database. |
Q37270405 | In situ Protein Detection for Companion Diagnostics |
Q27014174 | In vitro and in vivo models for analysis of resistance to anticancer molecular therapies |
Q38905987 | In vitro antiproliferative effect of trastuzumab (Herceptin(®)) combined with cetuximab (Erbitux(®)) in a model of human non-small cell lung cancer expressing EGFR and HER2. |
Q37250640 | In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation |
Q27853236 | In vitro modeling to determine mutation specificity of EGFR tyrosine kinase inhibitors against clinically relevant EGFR mutants in non-small-cell lung cancer |
Q39701114 | In vitro sequence-dependent synergism between paclitaxel and gefitinib in human lung cancer cell lines. |
Q38998235 | In vitro study of normoxic epidermal growth factor receptor-induced hypoxia-inducible factor-1-alpha, vascular endothelial growth factor, and BNIP3 expression in head and neck squamous cell carcinoma cell lines: Implications for anti-epidermal growt |
Q40031376 | In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags |
Q40290447 | In-frame deletion in the EGF receptor alters kinase inhibition by gefitinib |
Q40462593 | Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549. |
Q60921926 | Incense burning smoke sensitizes lung cancer cells to EGFR TKI by inducing AREG expression |
Q36406111 | Incidence and survival of non-small cell lung cancer in Shanghai: a population-based cohort study. |
Q35812244 | Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas |
Q33999412 | Including total EGFR staining in scoring improves EGFR mutations detection by mutation-specific antibodies and EGFR TKIs response prediction |
Q38406514 | Incorporating Erlotinib or Irinotecan Plus Cisplatin into Chemoradiotherapy for Stage III Non-small Cell Lung Cancer According to EGFR Mutation Status |
Q38545768 | Incorporating traditional and emerging biomarkers in the clinical management of metastatic colorectal cancer. |
Q37141676 | Incorporation of biologic therapies in the management of gastroesophageal cancers |
Q36759284 | Increased detection rates of EGFR and KRAS mutations in NSCLC specimens with low tumour cell content by 454 deep sequencing |
Q36082004 | Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms |
Q30279226 | Increased survival with the combination of stereotactic radiosurgery and gefitinib for non-small cell lung cancer brain metastasis patients: a nationwide study in Taiwan |
Q55425422 | Indirect comparison of efficacy and safety between immune checkpoint inhibitors and antiangiogenic therapy in advanced non-small-cell lung cancer. |
Q39367306 | Individual dose and scheduling determine the efficacy of combining cytotoxic anticancer agents with a kinase inhibitor in non-small-cell lung cancer |
Q36318541 | Individualised cancer therapeutics: dream or reality? |
Q36387788 | Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer |
Q42535408 | Individualization of treatment in non-small cell lung cancer |
Q86073879 | Individualized chemotherapy for osteosarcoma and identification of gene mutations in osteosarcoma |
Q37579648 | Individualized therapy in non-small-cell lung cancer: future versus current clinical practice |
Q38260343 | Individualizing kinase-targeted cancer therapy: the paradigm of chronic myeloid leukemia. |
Q26801711 | Induced pluripotent stem cell technology for dissecting the cancer epigenome |
Q37552307 | Inducible Mouse Models for Cancer Drug Target Validation |
Q36667008 | Induction of Apoptosis by PQ1, a Gap Junction Enhancer that Upregulates Connexin 43 and Activates the MAPK Signaling Pathway in Mammary Carcinoma Cells |
Q36026392 | Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas |
Q37486272 | Induction of E-cadherin in lung cancer and interaction with growth suppression by histone deacetylase inhibition |
Q34768930 | Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice |
Q24650438 | Induction of cancer-specific cytotoxicity towards human prostate and skin cells using quercetin and ultrasound |
Q90039016 | Influence of EGFR-activating mutations on sensitivity to tyrosine kinase inhibitors in a KRAS mutant non-small cell lung cancer cell line |
Q59794876 | Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases |
Q35200458 | Influence of chemotherapy on EGFR mutation status |
Q37659062 | Influence of chemotherapy on EGFR mutation status among patients with non-small-cell lung cancer. |
Q51770090 | Influence of histological type, smoking history and chemotherapy on survival after first-line therapy in patients with advanced non-small cell lung cancer. |
Q33586108 | Infrequent ERBB2 mutations in Chinese patients with non-small cell lung cancer |
Q58804391 | Inherited lung cancer syndromes targeting never smokers |
Q46782213 | Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. |
Q38970301 | Inhibiting epidermal growth factor receptor at a distance |
Q36764876 | Inhibiting kinases in malignant gliomas |
Q58207282 | Inhibition of EGFR Signaling Protects from Mucormycosis |
Q33227206 | Inhibition of EGFR signaling: all mutations are not created equal |
Q33571026 | Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel |
Q38866417 | Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells |
Q35261397 | Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis |
Q36150646 | Inhibition of angiogenesis in cancer patients |
Q38852858 | Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms |
Q33906140 | Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases |
Q24810622 | Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells |
Q24301761 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface |
Q35528877 | Inhibition of the epidermal growth factor receptor by erlotinib prevents immortalization of human cervical cells by Human Papillomavirus type 16 |
Q40210754 | Inhibition of the epidermal growth factor receptor in bladder cancer cells treated with the DNA-damaging drug etoposide markedly increases apoptosis. |
Q28079309 | Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical application |
Q33925323 | Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approach |
Q27851654 | Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer |
Q37111609 | Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma |
Q46613450 | Inhibitors of epidermoid growth factor receptor suppress cell growth and enhance chemosensitivity of nasopharyngeal cancer cells in vitro |
Q50866526 | Initiation of a formalized precision medicine program in gynecologic oncology. |
Q43807392 | Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma. |
Q37418930 | Insulin-like growth factor-1 receptor-targeted therapy for non-small cell lung cancer: a mini review |
Q34330521 | Insulin-like growth factors and neoplasia. |
Q37046462 | Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation |
Q37853183 | Integrating biomarkers in clinical trials |
Q28077310 | Integrating cancer genomic data into electronic health records |
Q33517983 | Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug? |
Q43040968 | Integrating molecular diagnostics into anticancer drug discovery. |
Q26769744 | Integrating the molecular background of targeted therapy and immunotherapy in lung cancer: a way to explore the impact of mutational landscape on tumor immunogenicity |
Q79227019 | Integration of EGFR inhibitors with radiochemotherapy |
Q38880324 | Integration of Stereotactic Body Radiation Therapy With Tyrosine Kinase Inhibitors in Stage IV Oncogene-Driven Lung Cancer |
Q28271520 | Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target |
Q38057720 | Integration of phosphoproteomic, chemical, and biological strategies for the functional analysis of targeted protein phosphorylation |
Q33673563 | Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas |
Q33774682 | Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients |
Q38322114 | Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer |
Q37216672 | Integrative genomic approaches to understanding cancer. |
Q30860315 | Integrative modeling of multi-platform genomic data under the framework of mediation analysis |
Q37301705 | Integrative transcriptome analysis identifies deregulated microRNA-transcription factor networks in lung adenocarcinoma. |
Q35482150 | Integrin beta-8 (ITGB8) silencing reverses gefitinib resistance of human hepatic cancer HepG2/G cell line |
Q39134067 | Inter-cellular adhesion disruption and the RAS/RAF and beta-catenin signalling in lung cancer progression |
Q46375753 | Interaction maps for kinase inhibitors |
Q33408501 | Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. |
Q41437605 | Intercalating and maintenance gefitinib plus chemotherapy versus chemotherapy alone in selected advanced non-small cell lung cancer with unknown EGFR status |
Q36474196 | Interfering with cell-survival signalling as a treatment strategy for prostate cancer. |
Q37689066 | Interleukin-1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma |
Q38673369 | Intermittent high-dose treatment with erlotinib enhances therapeutic efficacy in EGFR-mutant lung cancer |
Q28303718 | International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma |
Q52446289 | Interobserver variability in tumor contouring affects the use of radiomics to predict mutational status. |
Q36029824 | Interstitial lung disease in lung cancer: separating disease progression from treatment effects. |
Q42278411 | Interstitial lung disease in patients with non-small-cell lung cancer: causes, mechanisms and management |
Q36544282 | Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation. |
Q91941020 | Intracellular paired agent imaging enables improved evaluation of tyrosine kinase inhibitor target engagement |
Q37963231 | Intratumor heterogeneity and chemotherapy-induced changes in EGFR status in non-small cell lung cancer |
Q40005057 | Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib |
Q35994416 | Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition |
Q33700689 | Intratumoral distribution of EGFR mutations and copy number in metastatic lung cancer, what impact on the initial molecular diagnosis? |
Q24603941 | Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells |
Q36559630 | Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. |
Q26744339 | Intrinsic resistance to EGFR tyrosine kinase inhibitors in advanced non-small-cell lung cancer with activating EGFR mutations |
Q34273541 | Intrinsic resistance to selumetinib, a selective inhibitor of MEK1/2, by cAMP-dependent protein kinase A activation in human lung and colorectal cancer cells |
Q39131097 | Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation |
Q85857386 | Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation |
Q37736496 | Investigational EGFR-targeted therapy in head and neck squamous cell carcinoma |
Q46547397 | Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells. |
Q33821320 | Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib |
Q42743773 | Is EGFR expression important in non-small cell lung cancer? |
Q41092945 | Is MPP a good prognostic factor in stage III lung adenocarcinoma with EGFR exon 19 mutation? |
Q44607835 | Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer? |
Q26798882 | Is there a role for epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor wild-type non-small cell lung cancer? |
Q53060849 | Is there any predictor for clinical outcome in EGFR mutant NSCLC patients treated with EGFR TKIs? |
Q37537093 | Is vascular endothelial growth factor modulation a predictor of the therapeutic efficacy of gefitinib for bladder cancer? |
Q33403165 | Isolation of novel EGFR-specific VHH domains |
Q33936071 | It's about time: lessons for solid tumors from chronic myelogenous leukemia therapy |
Q35987345 | JAK2 inhibitor TG101348 overcomes erlotinib-resistance in non-small cell lung carcinoma cells with mutated EGF receptor |
Q39328532 | JAK2-related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor-activating mutation |
Q34879739 | Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area |
Q57909068 | KDR expression is associated with the stage and cigarette smoking of the patients with lung cancer |
Q53242395 | KL-6 and CEA levels in epithelial lining fluid microsamples predict response to gefitinib in patients with advanced non-small cell lung cancer. |
Q40542208 | KRAS Mutation Is a Significant Prognostic Factor in Early-stage Lung Adenocarcinoma |
Q37815135 | KRAS and BRAF: drug targets and predictive biomarkers |
Q21563446 | KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib |
Q37681051 | KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling |
Q37694808 | KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models |
Q42950523 | Keap1 mutations in lung cancer patients |
Q55083559 | Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice. |
Q41768010 | Key drivers of biomedical innovation in cancer drug discovery |
Q82150802 | Keynote comment: reimbursement for molecularly targeted anticancer agents |
Q46555496 | Killing time for cancer cells |
Q37060709 | Kinase inhibitor-responsive genotypes in EGFR mutated lung adenocarcinomas: moving past common point mutations or indels into uncommon kinase domain duplications and rearrangements |
Q34307423 | Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening |
Q37332008 | Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib |
Q39347810 | Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers |
Q64965123 | Knowledge base toward understanding actionable alterations and realizing precision oncology. |
Q38390205 | Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations-a review |
Q37728989 | L1198F Mutation Resensitizes Crizotinib to ALK by Altering the Conformation of Inhibitor and ATP Binding Sites |
Q35943143 | L858R-positive lung adenocarcinoma with KRAS G12V, EGFR T790M and EGFR L858R mutations: A case report |
Q64083382 | LAPTM4B is a novel diagnostic and prognostic marker for lung adenocarcinoma and associated with mutant EGFR |
Q43188970 | LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition |
Q64059672 | LUADpp: an effective prediction model on prognosis of lung adenocarcinomas based on somatic mutational features |
Q38206271 | LUX-Lung 3: redundancy, toxicity or a major step forward? Afatinib as front-line therapy for patients with metastatic EGFR-mutated lung cancer |
Q54296884 | LUX-Lung: determining the best EGFR inhibitor in NSCLC? |
Q37696232 | LYN expression predicts the response to dasatinib in a subpopulation of lung adenocarcinoma patients. |
Q58796615 | Label-free real-time ultrasensitive monitoring of non-small cell lung cancer cell interaction with drugs |
Q39400167 | Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity |
Q37755493 | Lack of Cetuximab induced skin toxicity in a previously irradiated field: case report and review of the literature |
Q54562020 | Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas. |
Q35753530 | Lack of EGFR mutations benefiting gefitinib treatment in adenocarcinoma of esophagogastric junction |
Q35889673 | Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles |
Q36616712 | Lack of clinical efficacy of imatinib in metastatic melanoma |
Q36439293 | Lack of epidermal growth factor receptor gene mutations in exons 19 and 21 in primary lymphoepithelioma-like carcinoma of the lung |
Q46965909 | Lack of prognostic value of EGFR mutations in primary resected non-small cell lung cancer |
Q50775865 | Lack of trastuzumab activity in nonsmall cell lung carcinoma with overexpression of erb-B2: 39810: a phase II trial of Cancer and Leukemia Group B. |
Q35831012 | Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations |
Q90631641 | Landscape of Mitochondria Genome and Clinical Outcomes in Stage 1 Lung Adenocarcinoma |
Q55485409 | Landscape of transcriptional deregulation in lung cancer. |
Q55070923 | Lapatinib-associated mucocutaneous toxicities are clinical predictors of improved progression-free survival in patients with human epidermal growth factor receptor (HER2)-positive advanced breast cancer. |
Q37059866 | Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature |
Q54486463 | Large-cell neuroendocrine carcinoma with epidermal growth factor receptor mutation: possible transformation of lung adenocarcinoma. |
Q33358603 | Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type |
Q33788680 | Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities |
Q47133535 | Leptomeningeal Disease and the Evolving Role of Molecular Targeted Therapy and Immunotherapy |
Q36851421 | Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers |
Q37810104 | Lestaurtinib: a multi-targeted FLT3 inhibitor |
Q37708018 | Leveraging Genomic Factors to Improve Benefit-Risk |
Q35965565 | Leveraging protein quaternary structure to identify oncogenic driver mutations |
Q52723140 | Lgr5+ intestinal stem cells reside in an unlicensed G1 phase. |
Q89762208 | Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET |
Q26797495 | Ligand-Independent EGFR Signaling |
Q36254464 | Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses |
Q35566222 | Ligand-independent phosphorylation of Y869 (Y845) links mutant EGFR signaling to stat-mediated gene expression |
Q26829104 | Ligand-triggered resistance to molecular targeted drugs in lung cancer: roles of hepatocyte growth factor and epidermal growth factor receptor ligands |
Q49684088 | Ligation-dependent RT-PCR: a new specific and low-cost technique to detect ALK, ROS, and RET rearrangements in lung adenocarcinoma. |
Q33931015 | Limited importance of the dominant-negative effect of TP53 missense mutations |
Q28253671 | Lineage dependency and lineage-survival oncogenes in human cancer |
Q38859701 | Liquid Biopsies in the Screening of Oncogenic Mutations in NSCLC and its Application in Targeted Therapy |
Q92028093 | Liquid Biopsy for the Detection of Resistance Mechanisms in NSCLC: Comparison of Different Blood Biomarkers |
Q39279845 | Liquid biopsy: unlocking the potentials of cell-free DNA. |
Q37716622 | Liver X receptors agonist GW3965 re-sensitizes gefitinib-resistant human non-small cell lung cancer cell to gefitinib treatment by inhibiting NF-κB in vitro |
Q36904551 | Local therapy with continued EGFR tyrosine kinase inhibitor therapy as a treatment strategy in EGFR-mutant advanced lung cancers that have developed acquired resistance to EGFR tyrosine kinase inhibitors |
Q37179405 | Locally advanced esophageal adenocarcinoma: current standards and molecular predictors of outcome |
Q38734500 | Long and short noncoding RNAs in lung cancer precision medicine: Opportunities and challenges |
Q42366666 | Long non-coding RNAs associated with non-small cell lung cancer |
Q38682910 | Long noncoding RNAs: emerging regulators of tumor angiogenesis |
Q102057123 | Long term follow-up of EGFR mutated NSCLC cases |
Q53823427 | Long-term safety and survival with gefitinib in select patients with advanced non-small cell lung cancer: Results from the US IRESSA Clinical Access Program (ICAP). |
Q34130681 | Long-term survival outcomes by smoking status in surgical and nonsurgical patients with non-small cell lung cancer: comparing never smokers and current smokers. |
Q51147438 | Long-term treatment with EGFR inhibitor erlotinib attenuates renal inflammatory cytokines but not nephropathy in Alport syndrome mouse model. |
Q98466270 | Longitudinal Monitoring of EGFR and PIK3CA Mutations by Saliva-Based EFIRM in Advanced NSCLC Patients With Local Ablative Therapy and Osimertinib Treatment: Two Case Reports |
Q36916399 | Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02) |
Q89622158 | Looking for the high way in EGFR-positive non-small cell lung cancer through the evaluation of survival endpoints |
Q49340076 | Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization. |
Q49359622 | Losmapimod: A Novel Clinical Drug to Overcome Gefitinib-Resistance. |
Q33977056 | Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance |
Q36028210 | Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma |
Q28481370 | Loss of activating EGFR mutant gene contributes to acquired resistance to EGFR tyrosine kinase inhibitors in lung cancer cells |
Q36503161 | Loss of epidermal growth factor receptor expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition |
Q47653923 | Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells |
Q33779389 | Loss-of-function CYP2C9 variants: finding the correct clinical role for Type 2 diabetes pharmacogenetic testing |
Q39970216 | Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status |
Q54440196 | Low prevalence of K-RAS, EGF-R and BRAF mutations in sinonasal adenocarcinomas. Implications for anti-EGFR treatments. |
Q92577499 | Low-abundance mutations in colorectal cancer patients and healthy adults |
Q38868797 | Low-fidelity alternative DNA repair carcinogenesis theory may interpret many cancer features and anticancer strategies |
Q39096391 | Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model |
Q36761452 | Lung Adenocarcinoma with Anaplastic Lymphoma Kinase (ALK) Rearrangement Presenting as Carcinoma of Unknown Primary Site: Recognition and Treatment Implications |
Q39350278 | Lung Cancer Epidemiology in Korea. |
Q38679289 | Lung Cancer Genomics in the Era of Accelerated Targeted Drug Development. |
Q28386607 | Lung Cancer: Are we up to the Challenge? |
Q53776017 | Lung Cancer: EGFR Inhibitors with Low Nanomolar Activity against a Therapy-Resistant L858R/T790M/C797S Mutant. |
Q47127472 | Lung Cancer: Understanding Its Molecular Pathology and the 2015 WHO Classification |
Q35887906 | Lung adenocarcinoma and human papillomavirus infection |
Q53534519 | Lung adenocarcinoma and its thyroid metastasis characterized on fine-needle aspirates by cytomorphology, immunocytochemistry, and next-generation sequencing. |
Q34281228 | Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases |
Q33967404 | Lung adenocarcinoma harboring L858R and T790M mutations in epidermal growth factor receptor, with poor response to gefitinib: A case report |
Q35790212 | Lung adenocarcinoma harboring mutations in the ERBB2 kinase domain |
Q36962487 | Lung adenocarcinoma in the era of targeted therapies: histological classification, sample prioritization, and predictive biomarkers |
Q89579716 | Lung adenocarcinoma patient with an EGFR kinase domain duplication (KDD) and the response to icotinib |
Q37438296 | Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers |
Q53403793 | Lung adenocarcinoma: Assessment of epidermal growth factor receptor mutation status based on extended models of diffusion-weighted image. |
Q37147755 | Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond |
Q34666826 | Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors |
Q35207787 | Lung cancer and lung injury: the dual role of ceramide |
Q37487153 | Lung cancer biology: a genetic and genomic perspective. |
Q26775396 | Lung cancer biomarkers, targeted therapies and clinical assays |
Q33861083 | Lung cancer cytology: potential pitfalls and mimics - a review |
Q29615414 | Lung cancer in never smokers--a different disease |
Q58804388 | Lung cancer in never smokers-the East Asian experience |
Q34177155 | Lung cancer in never smokers: molecular profiles and therapeutic implications |
Q36026075 | Lung cancer in never-smokers |
Q35861107 | Lung cancer in the era of precision medicine |
Q44477692 | Lung cancer in women: the differences in epidemiology, biology and treatment outcomes |
Q39356534 | Lung cancer samples preserved in liquid medium: One step beyond cytology |
Q34541960 | Lung cancer therapeutics that target signaling pathways: an update |
Q38476124 | Lung cancer treatment - Biology based decision, from gene to histology |
Q37114965 | Lung cancer with concurrent EGFR mutation and ROS1 rearrangement: a case report and review of the literature |
Q35667888 | Lung cancer, thyroid cancer or both: An unusual case presentation |
Q36328370 | Lung cancer: Biology and treatment options |
Q46049056 | Lung cancer: New biological insights and recent therapeutic advances |
Q37622985 | Lung cancer: a biologically different disease in women? |
Q87903213 | Lung cancer: dropping bars or rising hoops--phase III outcomes of NSCLC |
Q34354426 | Lung cancer: intragenic ERBB2 kinase mutations in tumours |
Q39741320 | Lung cancers unrelated to smoking: characterized by single oncogene addiction? |
Q36140332 | Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1. |
Q34104798 | Lung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke |
Q37755025 | Lung microRNA: from development to disease |
Q36501975 | Lungs don't forget: Comparison of the KRAS and EGFR mutation profile and survival of collegiate smokers and never smokers with advanced lung cancers |
Q54337332 | M2-polarized macrophages contribute to the decreased sensitivity of EGFR-TKIs treatment in patients with advanced lung adenocarcinoma. |
Q37268998 | MAPK1E322K mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin |
Q96431732 | MDL-800, an allosteric activator of SIRT6, suppresses proliferation and enhances EGFR-TKIs therapy in non-small cell lung cancer |
Q38051474 | MEK and RAF inhibitors for BRAF-mutated cancers |
Q37427045 | MEK inhibitors against MET-amplified non-small cell lung cancer |
Q42354586 | MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated. |
Q42019758 | MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E. |
Q35872321 | MEK1/2 inhibitor selumetinib (AZD6244) inhibits growth of ovarian clear cell carcinoma in a PEA-15-dependent manner in a mouse xenograft model |
Q36788312 | MET Exon 14 Skipping in Non-Small Cell Lung Cancer. |
Q35606387 | MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation |
Q28551045 | MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells |
Q38709287 | MET amplification and epithelial-to-mesenchymal transition exist as parallel resistance mechanisms in erlotinib-resistant, EGFR-mutated, NSCLC HCC827 cells |
Q27851406 | MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling |
Q24646295 | MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib |
Q37520331 | MET exon 14 skipping defines a unique molecular class of non-small cell lung cancer |
Q36140765 | MET expression and copy number heterogeneity in nonsquamous non-small cell lung cancer (nsNSCLC). |
Q37399525 | MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors |
Q38390016 | MET inhibition in lung cancer |
Q34033952 | MET receptor sequence variants R970C and T992I lack transforming capacity |
Q64929599 | MICAL-L2 potentiates Cdc42-dependent EGFR stability and promotes gastric cancer cell migration. |
Q35417648 | ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. |
Q35781614 | MLH1 V384D polymorphism associates with poor response to EGFR tyrosine kinase inhibitors in patients with EGFR L858R-positive lung adenocarcinoma |
Q33570512 | MMP9 but Not EGFR, MET, ERCC1, P16, and P-53 Is Associated with Response to Concomitant Radiotherapy, Cetuximab, and Weekly Cisplatin in Patients with Locally Advanced Head and Neck Cancer |
Q38803437 | MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma. |
Q39311676 | Macroporous hydrogel micropillars for quantifying Met kinase activity in cancer cell lysates |
Q39293814 | Major Tumor Suppressor and Oncogenic Non-Coding RNAs: Clinical Relevance in Lung Cancer. |
Q64054076 | Major vault protein suppresses lung cancer cell proliferation by inhibiting STAT3 signaling pathway |
Q46070125 | Making a difference with teamwork. |
Q33846850 | Making sense of cancer genomic data |
Q90947631 | Making the first move in EGFR-driven or ALK-driven NSCLC: first-generation or next-generation TKI? |
Q38089834 | Malignant glioma drug discovery - targeting protein kinases |
Q36499234 | Malignant gliomas: strategies to increase the effectiveness of targeted molecular treatment |
Q35108421 | Malignant pleural effusion supernatants are substitutes for metastatic pleural tumor tissues in EGFR mutation test in patients with advanced lung adenocarcinoma |
Q54166640 | Management Strategies for Adverse Events Associated With EGFR TKIs in Non-Small Cell Lung Cancer. |
Q90300758 | Management of Brain Metastases in Epidermal Growth Factor Receptor Mutant Non-Small-Cell Lung Cancer |
Q38685481 | Management of EGFR-mutated non-small-cell lung cancer: practical implications from a clinical and pathology perspective |
Q38258633 | Management of NSCLC: focus on crizotinib |
Q49887989 | Management of acquired resistance to EGFR TKI-targeted therapy in advanced non-small cell lung cancer. |
Q26865779 | Management of acquired resistance to epidermal growth factor receptor kinase inhibitors in patients with advanced non-small cell lung cancer |
Q38131165 | Management of non-small-cell lung cancer: recent developments |
Q33892597 | Management of patients with advanced non-small cell lung cancer: role of gefitinib |
Q90167972 | Managing Lung Cancer with Comorbid Interstitial Pneumonia |
Q37003374 | Markers of systemic inflammation predict survival in patients with advanced renal cell cancer. |
Q34350615 | Mass spectrometry-based proteomics: the road to lung cancer biomarker discovery |
Q37706977 | Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2. |
Q33398142 | Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy |
Q59800637 | Mechanism of Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors and a Potential Treatment Strategy |
Q52568478 | Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer. |
Q36682301 | Mechanisms and insights into drug resistance in cancer |
Q34277873 | Mechanisms behind the inhibition of lung adenocarcinoma cell by shikonin |
Q38459398 | Mechanisms of Acquired Resistance to ALK Inhibitors and the Rationale for Treating ALK-positive Lung Cancer |
Q37217229 | Mechanisms of Disease: signal transduction in lung carcinogenesis -- a comparison of smokers and never-smokers |
Q28069900 | Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma |
Q38669280 | Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors and Therapeutic Approaches: An Update |
Q42043613 | Mechanisms of Resistance to Epidermal Growth Factor Receptor Inhibitors and Novel Therapeutic Strategies to Overcome Resistance in NSCLC Patients |
Q39185608 | Mechanisms of Resistance to Immune Checkpoint Antibodies. |
Q52312436 | Mechanisms of Resistance to Target Therapies in Non-small Cell Lung Cancer. |
Q50146512 | Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors. |
Q39308771 | Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line. |
Q38034816 | Mechanisms of acquired resistance to targeted cancer therapies. |
Q36559283 | Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy |
Q36953160 | Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway--therapeutic perspectives in cancer |
Q36472437 | Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer |
Q39056242 | Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis |
Q35043706 | Mechanisms of resistance to EGFR TKIs and development of a new generation of drugs in non-small-cell lung cancer |
Q36887721 | Mechanisms of resistance to EGFR targeted therapies |
Q28077415 | Mechanisms of resistance to EGFR-targeted drugs: lung cancer |
Q39242812 | Mechanisms of resistance to ErbB-targeted cancer therapeutics |
Q37671920 | Mechanisms of resistance to HER family targeting antibodies |
Q28074073 | Mechanisms of resistance to anti-EGFR therapy in colorectal cancer |
Q97538337 | Mechanisms of resistance to osimertinib |
Q36942619 | Mechanisms of resistance to reversible inhibitors of EGFR tyrosine kinase in non-small cell lung cancer. |
Q36573324 | Mechanisms of resistance to small molecule kinase inhibition in the treatment of solid tumors |
Q83390165 | Mechanisms of tumor resistance to EGFR-targeted therapies |
Q90333285 | Mechanistic insights into differential requirement of receptor dimerization for oncogenic activation of mutant EGFR and its clinical perspective |
Q39603355 | Mechanistic insights into the activation of oncogenic forms of EGF receptor |
Q36107597 | Mediastinal staging of NSCLC with endoscopic and endobronchial ultrasound |
Q98467275 | Medical management of brain metastases |
Q42190258 | Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice |
Q36772001 | Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells |
Q34749765 | Membrane-anchored growth factors, the epidermal growth factor family: beyond receptor ligands |
Q36249213 | Membrane-bound estrogen receptor-α expression and epidermal growth factor receptor mutation are associated with a poor prognosis in lung adenocarcinoma patients |
Q36224439 | Membranous and cytoplasmic expression of epidermal growth factor receptor in metastatic pancreatic ductal adenocarcinoma |
Q30415408 | Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells |
Q39911616 | Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer |
Q34449385 | Meta-analysis of first-line therapies in advanced non-small-cell lung cancer harboring EGFR-activating mutations |
Q91646512 | Metabolic Remodelling: An Accomplice for New Therapeutic Strategies to Fight Lung Cancer |
Q36903072 | Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer |
Q35588724 | Metaplastic breast carcinomas are negative for Her-2 but frequently express EGFR (Her-1): potential relevance to adjuvant treatment with EGFR tyrosine kinase inhibitors? |
Q25257542 | Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis |
Q36031278 | Metastatic Squamous Cell Carcinoma Component from an Adenosquamous Carcinoma of the Lung with Identical Epidermal Growth Factor Receptor Mutations |
Q37871213 | Metastatic non-small-cell lung cancer: consensus on pathology and molecular tests, first-line, second-line, and third-line therapy: 1st ESMO Consensus Conference in Lung Cancer; Lugano 2010. |
Q93379419 | Metastatic osteosarcoma challenged by regorafenib |
Q92597887 | Metformin Prolongs Survival in Type 2 Diabetes Lung Cancer Patients With EGFR-TKIs |
Q37848661 | Methodological and practical challenges for personalized cancer therapies |
Q36540555 | Methodological aspects of current problems in target-based anticancer drug development |
Q35925441 | Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance |
Q42013793 | Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma |
Q38833904 | MiR-122 Induces Radiosensitization in Non-Small Cell Lung Cancer Cell Line |
Q37274389 | MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers |
Q37681498 | MiRNA-125a-5p: a regulator and predictor of gefitinib's effect on nasopharyngeal carcinoma |
Q37702742 | MicroRNA expression profiles and clinicopathological implications in lung adenocarcinoma according to EGFR, KRAS, and ALK status |
Q39433270 | MicroRNA-21 versus microRNA-34: Lung cancer promoting and inhibitory microRNAs analysed in silico and in vitro and their clinical impact |
Q38826622 | MicroRNA-221 targets PTEN to reduce the sensitivity of cervical cancer cells to gefitinib through the PI3K/Akt signaling pathway |
Q42315789 | MicroRNA-30e reduces cell growth and enhances drug sensitivity to gefitinib in lung carcinoma |
Q37723702 | MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab |
Q36429673 | MicroRNAs as a potential magic bullet in cancer. |
Q38917573 | MicroRNAs in non-small cell lung cancer and idiopathic pulmonary fibrosis. |
Q37297730 | MicroRNAs in the pathogenesis of Lung Cancer |
Q42354892 | MicroRNAs: a new tool in the complex biology of KRAS mutated non-small cell lung cancer? |
Q38430945 | Microarray gene expression analysis of chemosensitivity for docetaxel, cisplatin and 5-fluorouracil (TPF) combined chemotherapeutic regimen in hypopharyngeal squamous cell carcinoma |
Q34975977 | Micropapillary lung adenocarcinoma: EGFR, K-ras, and BRAF mutational profile |
Q26748947 | Migraine in the era of precision medicine |
Q39214395 | Milestones in the systemic treatment of lung cancer |
Q64936082 | Miliary lung metastases from non-small cell lung cancer with Exon 20 insertion: A dismal prognostic entity: A case report. |
Q48125418 | Miliary metastases are associated with epidermal growth factor receptor mutations in non-small cell lung cancer: a population-based study. |
Q34796086 | Mind-mapping for lung cancer: towards a personalized therapeutics approach |
Q33631471 | Minireview: Familiar Faces in Unfamiliar Places: The Emerging Role of Nuclear Receptors in Lung Cancer |
Q35679203 | Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction |
Q40467961 | Missense Mutations in Exons 18-24 of EGFR in Hepatocellular Carcinoma Tissues. |
Q37347485 | Mitochondria: gatekeepers of response to chemotherapy |
Q39890068 | Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase |
Q64298060 | Mixed response to osimertinib and the beneficial effects of additional local therapy |
Q36910615 | Modeling NSCLC progression: recent advances and opportunities available |
Q92531307 | Modeling Tumor Growth and Treatment Resistance Dynamics Characterizes Different Response to Gefitinib or Chemotherapy in Non-Small Cell Lung Cancer |
Q38721547 | Modeling gene-wise dependencies improves the identification of drug response biomarkers in cancer studies |
Q28484612 | Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression |
Q36840172 | Modeling oncogene addiction using RNA interference. |
Q89598805 | Molecular Analysis of Liquid-Based Cytological Specimen Using Virtually Positive Sputum with Adenocarcinoma Cells |
Q37120887 | Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase |
Q28070038 | Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective |
Q58700723 | Molecular Diagnostics in Clinical Oncology |
Q35849985 | Molecular Epidemiology of EGFR Mutations in Asian Patients with Advanced Non-Small-Cell Lung Cancer of Adenocarcinoma Histology - Mainland China Subset Analysis of the PIONEER study |
Q35216709 | Molecular Imaging in Optical Coherence Tomography |
Q34213559 | Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation |
Q26771116 | Molecular Pathology and Personalized Medicine: The Dawn of a New Era in Companion Diagnostics-Practical Considerations about Companion Diagnostics for Non-Small-Cell-Lung-Cancer |
Q42926986 | Molecular Predictors of Sensitivity to the MET Inhibitor PHA665752 in Lung Carcinoma Cells |
Q37347532 | Molecular Targeted Drugs and Biomarkers in NSCLC, the Evolving Role of Individualized Therapy |
Q37589551 | Molecular Targeted Therapy in Modern Oncology: Imaging Assessment of Treatment Response and Toxicities |
Q38869420 | Molecular Targeting of Growth Factor Receptor Signaling in Radiation Oncology |
Q47141828 | Molecular Targets in Non-Small Cell Lung Cancer |
Q38582997 | Molecular Testing in Multiple Synchronous Lung Adenocarcinomas: Case Report and Literature Review |
Q55564375 | Molecular Therapies in Thyroid Cancer. |
Q38258822 | Molecular alterations in non-small-cell lung cancer: perspective for targeted therapy and specimen management for the bronchoscopist |
Q37683112 | Molecular alterations in uterine serous carcinoma |
Q37349875 | Molecular alterations of EGFR and PIK3CA in uterine serous carcinoma |
Q51019080 | Molecular alterations of EGFR in small intestinal adenocarcinoma. |
Q37350516 | Molecular analysis of metaplastic breast carcinoma: high EGFR copy number via aneusomy |
Q46594292 | Molecular analysis of the EGFR gene in astrocytic gliomas: mRNA expression, quantitative-PCR analysis of non-homogeneous gene amplification and DNA sequence alterations. |
Q30811836 | Molecular analysis of the EGFR-RAS-RAF pathway in pancreatic ductal adenocarcinomas: lack of mutations in the BRAF and EGFR genes |
Q38292199 | Molecular analysis-based treatment strategies for non-small cell lung cancer |
Q33843578 | Molecular and clinical responses in a pilot study of gefitinib with paclitaxel and radiation in locally advanced head-and-neck cancer |
Q36993693 | Molecular basis for multimerization in the activation of the epidermal growth factor receptor |
Q36612550 | Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis. |
Q24606677 | Molecular biology of lung cancer |
Q37653893 | Molecular biology of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. |
Q24610335 | Molecular biology of lung cancer: clinical implications |
Q36273001 | Molecular biology of medulloblastoma: will it ever make a difference to clinical management? |
Q33969308 | Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study |
Q63366116 | Molecular characterisation and liquid biomarkers in Carcinoma of Unknown Primary (CUP): taking the ‘U’ out of ‘CUP’ |
Q34778891 | Molecular characteristics of non-small cell lung cancer with reduced CHFR expression in The Cancer Genome Atlas (TCGA) project |
Q35681816 | Molecular characteristics predict clinical outcomes: prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene |
Q33475963 | Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. |
Q89426902 | Molecular characterization of pulmonary sarcomatoid carcinoma: analysis of 33 cases |
Q37666114 | Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance |
Q36240941 | Molecular chess? Hallmarks of anti-cancer drug resistance |
Q56795277 | Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay |
Q58053853 | Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis |
Q43805944 | Molecular determinations of EGFR and EML4-ALK on a single slide of NSCLC tissue |
Q48458378 | Molecular diagnostic algorithm for epidermal growth factor receptor mutation detection in Asian lung adenocarcinomas: comprehensive analyses of 445 Taiwanese patients with immunohistochemistry, PCR-direct sequencing and Scorpion/ARMS methods. |
Q37037132 | Molecular diagnostic testing in malignant gliomas: a practical update on predictive markers |
Q43226909 | Molecular diagnostics in lung carcinoma for therapy stratification |
Q43690882 | Molecular diagnostics of lung cancer in the clinic |
Q36370600 | Molecular diagnostics of non-small cell lung cancer using mediastinal lymph nodes sampled by endoscopic ultrasound-guided needle aspiration |
Q42822469 | Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases |
Q51099791 | Molecular dynamics and pharmacophore modelling studies of different subtype (ALK and EGFR (T790M)) inhibitors in NSCLC. |
Q41144243 | Molecular dynamics simulation analysis of the effect of T790M mutation on epidermal growth factor receptor protein architecture in non-small cell lung carcinoma |
Q64265169 | Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare mutations |
Q24611043 | Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers |
Q42951192 | Molecular factors related to gefitinib efficacy in advanced non-small cell lung cancer |
Q38117105 | Molecular genetic testing for lung adenocarcinomas: a practical approach to clinically relevant mutations and translocations |
Q37206476 | Molecular genetics of lung cancer in people who have never smoked |
Q37732704 | Molecular imaging and targeted therapies |
Q48451660 | Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography. |
Q34534164 | Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT |
Q37061902 | Molecular imaging of nonsmall cell lung carcinomas expressing active mutant EGFR kinase using PET with [(124)i]-morpholino-IPQA |
Q28544659 | Molecular interaction of a kinase inhibitor midostaurin with anticancer drug targets, S100A8 and EGFR: transcriptional profiling and molecular docking study for kidney cancer therapeutics |
Q36673960 | Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors |
Q36634023 | Molecular markers of prognosis and novel therapeutic strategies for urothelial cell carcinomas |
Q34560236 | Molecular mechanism of the schedule-dependent synergistic interaction in EGFR-mutant non-small cell lung cancer cell lines treated with paclitaxel and gefitinib |
Q42290027 | Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells |
Q39411432 | Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers |
Q33828409 | Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy |
Q35104755 | Molecular mechanisms of cigarette smoke-induced proliferation of lung cells and prevention by vitamin C. |
Q38060727 | Molecular mechanisms of lung-specific toxicity induced by epidermal growth factor receptor tyrosine kinase inhibitors |
Q35001415 | Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab |
Q39172297 | Molecular mechanisms of therapy resistance in solid tumors: chasing "moving" targets |
Q26769659 | Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs |
Q36567573 | Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer. |
Q35256622 | Molecular methods for somatic mutation testing in lung adenocarcinoma: EGFR and beyond |
Q36468815 | Molecular modeling and description of a newly characterized activating mutation of the EGFR gene in non-small cell lung cancer |
Q37602884 | Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype |
Q37919395 | Molecular oncology of lung cancer |
Q38012566 | Molecular pathogenesis of malignant mesothelioma |
Q38459875 | Molecular pathology in oncology--the AstraZeneca perspective |
Q34194997 | Molecular pathology of lung cancer: current status and future directions |
Q27691299 | Molecular pathology of lung cancer: key to personalized medicine |
Q27690919 | Molecular pathology of non-small cell lung cancer: a practical guide |
Q36868012 | Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition |
Q37606747 | Molecular predictive and prognostic markers in non-small-cell lung cancer. |
Q36772562 | Molecular predictors of EGFR-TKI sensitivity in advanced non-small cell lung cancer |
Q36788498 | Molecular predictors of chemotherapy response in non-small-cell lung cancer |
Q36498832 | Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer |
Q33696507 | Molecular profile of lung cancer in never smokers |
Q92536292 | Molecular profile of non-small cell lung cancer in northeastern Brazil |
Q36691733 | Molecular profiling of lung carcinoma: identifying clinically useful tumor markers for diagnosis and prognosis |
Q37417261 | Molecular profiling of sinonasal undifferentiated carcinoma |
Q54461448 | Molecular profiling of thin-prep FNA samples in assisting clinical management of non-small-cell lung cancer. |
Q26830588 | Molecular recognition of gangliosides and their potential for cancer immunotherapies |
Q44070495 | Molecular spectrum of somatic EGFR and KRAS gene mutations in non small cell lung carcinoma: determination of frequency, distribution pattern and identification of novel variations in Indian patients |
Q39214067 | Molecular subtype and response to dasatinib, an Src/Abl small molecule kinase inhibitor, in hepatocellular carcinoma cell lines in vitro |
Q33609045 | Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing |
Q36944441 | Molecular targeted therapies for pancreatic cancer |
Q46780845 | Molecular targeted therapy for lung cancer |
Q36547758 | Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors |
Q26828860 | Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors |
Q34159011 | Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular |
Q26824599 | Molecular testing in lung cancer in the era of precision medicine |
Q37771888 | Molecular testing in lung cancer: the time is now. |
Q92326347 | Molecular testing strategies in non-small cell lung cancer: optimizing the diagnostic journey |
Q34608584 | Molecular therapeutic advances in personalized therapy of melanoma and non-small cell lung cancer |
Q37458175 | Molecular therapy in head and neck oncology |
Q33699594 | Molecular tumor board: the University of California-San Diego Moores Cancer Center experience |
Q47130146 | Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms. |
Q36929734 | Molecularly targeted approaches herald a new era of non-small-cell lung cancer treatment |
Q36859958 | Molecularly targeted therapies for advanced or metastatic non-small-cell lung carcinoma |
Q33644407 | Molecularly targeted therapies for malignant glioma: rationale for combinatorial strategies |
Q35136424 | Molecularly targeted therapies in non-small-cell lung cancer annual update 2014 |
Q36829847 | Molecularly targeted therapy for malignant glioma |
Q36326239 | Molecularly-targeted therapies for non-small cell lung cancer |
Q46793091 | Molecule-kinase interaction map. |
Q35962944 | Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR. |
Q80100680 | Monitoring EGFR-mutant lung cancers by means of the blood |
Q35004426 | Monitoring of epidermal growth factor receptor tyrosine kinase inhibitor-sensitizing and resistance mutations in the plasma DNA of patients with advanced non-small cell lung cancer during treatment with erlotinib |
Q36514558 | Monitoring of high-density lipoprotein cholesterol level is predictive of EGFR mutation and efficacy of EGFR-TKI in patients with advanced lung adenocarcinoma |
Q47617131 | Monoamines in Glioblastoma: complex biology with therapeutic potential. |
Q37051227 | Morphine-induced epidermal growth factor pathway activation in non-small cell lung cancer |
Q33594324 | Morphologic features of adenocarcinoma of the lung predictive of response to the epidermal growth factor receptor kinase inhibitors erlotinib and gefitinib |
Q38765690 | Morphometric and cytomorphologic characterization of EGFR-mutated cancer cells-comparison between cultured lung cancer cell lines and lung adenocarcinoma clinical samples |
Q36184798 | Morphoproteomics: exposing protein circuitries in tumors to identify potential therapeutic targets in cancer patients |
Q38431277 | Mouse hospital and co-clinical trial project--from bench to bedside. |
Q36547732 | Mouse models of human non-small-cell lung cancer: raising the bar. |
Q47108604 | Moving more potent and less toxic options to the frontline in the management of advanced lung cancer |
Q24683814 | Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features |
Q35541778 | Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience |
Q82976088 | Multicenter Phase II trial of high-dose imatinib mesylate in metastatic melanoma: significant toxicity with no clinical efficacy |
Q84444587 | Multicenter analysis of lung cancer patients younger than 45 years in Shanghai |
Q36494159 | Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403). |
Q35799619 | Multigene amplification and massively parallel sequencing for cancer mutation discovery |
Q36936796 | Multimodality imaging of the HER-kinase axis in cancer |
Q34123261 | Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin |
Q35237841 | Multiplatform comparison of molecular oncology tests performed on cytology specimens and formalin-fixed, paraffin-embedded tissue. |
Q89747760 | Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy |
Q39246320 | Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer |
Q59807868 | Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC |
Q41986671 | Multiplex Real-Time PCR Assays that Measure the Abundance of Extremely Rare Mutations Associated with Cancer |
Q40479483 | Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR. |
Q35169273 | Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry |
Q37595545 | Multiplexed fluorescence imaging of tumor biomarkers in gene expression and protein levels for personalized and predictive medicine |
Q91741802 | Multiplexed molecular profiling of lung cancer with malignant pleural effusion using next generation sequencing in Chinese patients |
Q36163327 | Multiplexed quantification of estrogen receptor and HER2/Neu in tissue and cell lysates by peptide immunoaffinity enrichment mass spectrometry |
Q37633877 | Multiplexed transcriptome analysis to detect ALK, ROS1 and RET rearrangements in lung cancer |
Q37443767 | Multiscale cancer modeling |
Q51128947 | Mutant allele frequency predicts the efficacy of EGFR-TKIs in lung adenocarcinoma harboring the L858R mutation. |
Q59812799 | Mutation Detection and Its Association With Clinicopathological Characters of Lung Cancer Patients |
Q89206835 | Mutation Yield of a 34-Gene Solid Tumor Panel in Community-Based Tumor Samples |
Q52642806 | Mutation abundance affects the therapeutic efficacy of EGFR-TKI in patients with advanced lung adenocarcinoma: A retrospective analysis. |
Q38804094 | Mutation analysis of EGFR and its correlation with the HPV in Indian cervical cancer patients. |
Q31162700 | Mutation analysis of genes in the EGFR pathway in Head and Neck cancer patients: implications for anti-EGFR treatment response |
Q51437092 | Mutation analysis of the EGFR gene and its downstream signaling pathway in thymic carcinoma patients from a Chinese Han population. |
Q55004879 | Mutation analysis of the EGFR pathway genes, EGFR, RAS, PIK3CA, BRAF, and AKT1, in salivary gland adenoid cystic carcinoma. |
Q40149065 | Mutation and polymorphism in the EGFR-TK domain associated with lung cancer. |
Q60445017 | Mutation de l’EGFR, de l’étude du gène à la pratique clinique : exemplarité ou exception ? |
Q33412122 | Mutation detection by real-time PCR: a simple, robust and highly selective method |
Q33856261 | Mutation detection of epidermal growth factor receptor and KRAS genes using the smart amplification process version 2 from formalin-fixed, paraffin-embedded lung cancer tissue |
Q50613227 | Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors. |
Q39813481 | Mutation of epidermal growth factor receptor is associated with MIG6 expression |
Q36383360 | Mutation of the PIK3CA oncogene in human cancers |
Q40237141 | Mutation profile of EGFR gene detected by denaturing high-performance liquid chromatography in Japanese lung cancer patients |
Q43223369 | Mutation profile of JAK2 transcripts in patients with chronic myeloproliferative neoplasias |
Q34457501 | Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform |
Q28484396 | Mutation scanning using MUT-MAP, a high-throughput, microfluidic chip-based, multi-analyte panel |
Q54373177 | Mutation status of somatic EGFR and KRAS genes in Chinese patients with prostate cancer (PCa). |
Q37512938 | Mutation-associated fusion cancer genes in solid tumors. |
Q97885892 | Mutational Portrait of Lung Adenocarcinoma in Brazilian Patients: Past, Present, and Future of Molecular Profiling in the Clinic |
Q55281004 | Mutational Screening in Tyrosine-Kinase Domain of erbB1 And erbB2 Genes. |
Q36824808 | Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis |
Q46881384 | Mutational activation of ErbB2 reveals a new protein kinase autoinhibition mechanism |
Q37558631 | Mutational analyses of multiple oncogenic pathways in intraductal papillary mucinous neoplasms of the pancreas. |
Q54671910 | Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas. |
Q33283995 | Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4 |
Q35948040 | Mutational analysis of the insulin-like growth factor 1 receptor tyrosine kinase domain in non-small cell lung cancer patients |
Q34650735 | Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1 |
Q41545847 | Mutational frequency of KRAS, NRAS, IDH2, PIK3CA, and EGFR in North Indian gallbladder cancer patients. |
Q21261249 | Mutational profiling of kinases in glioblastoma |
Q41535851 | Mutational profiling of second primary lung cancers in patients who have received radiation for the treatment of Hodgkin's disease |
Q33534522 | Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer |
Q34747189 | Mutations in epidermal growth factor receptor gene in esophageal squamous cell carcinoma patients in kashmir- a high incidence area of India. |
Q27851720 | Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer |
Q24669579 | Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas |
Q35558988 | Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy |
Q37110011 | Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers. |
Q36615150 | Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma |
Q37823422 | Mutations in the epidermal growth factor receptor gene in non-small cell lung cancer: Impact on treatment beyond gefitinib and erlotinib |
Q80241919 | Mutations in the epidermal growth factor receptor tyrosine kinase may predict response to gefitinib in non-small-cell lung cancer |
Q37349031 | Mutations in the polybasic juxtamembrane sequence of both plasma membrane- and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell transformation |
Q46973585 | Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma |
Q51051494 | Mutations of the EGFR and K-ras genes in resected stage I lung adenocarcinoma and their clinical significance. |
Q52892289 | Mutations of the EGFR, K-ras, EML4-ALK, and BRAF genes in resected pathological stage I lung adenocarcinoma. |
Q36121584 | Mutations of the epidermal growth factor receptor gene in NSCLC patients |
Q35551048 | Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking |
Q35380919 | N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells |
Q34631703 | N-cadherin expression is associated with acquisition of EMT phenotype and with enhanced invasion in erlotinib-resistant lung cancer cell lines |
Q38631853 | NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor |
Q64055892 | NGFI-A Binding Protein 2 Promotes EGF-Dependent HNSCC Cell Invasion |
Q92255821 | NSCLC Mutated Isoforms of CCDC6 Affect the Intracellular Distribution of the Wild Type Protein Promoting Cisplatinum Resistance and PARP Inhibitors Sensitivity in Lung Cancer Cells |
Q38793074 | NSCLC harboring EGFR exon-20 insertions after the regulatory C-helix of kinase domain responds poorly to known EGFR inhibitors |
Q35063769 | NVP-BEZ235 overcomes gefitinib-acquired resistance by down-regulating PI3K/AKT/mTOR phosphorylation |
Q27011692 | Nanomedicine therapeutic approaches to overcome cancer drug resistance |
Q57377197 | Nanoparticles combined with growth factors: recent progress and applications |
Q37822705 | Nanoparticles for the development of improved (bio)sensing systems |
Q28072745 | Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes |
Q24305218 | Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors |
Q34551144 | Nedd4-1 is an exceptional prognostic biomarker for gastric cardia adenocarcinoma and functionally associated with metastasis |
Q42292974 | Neoadjuvant Oncogene-Targeted Therapy in Early Stage Non-Small-Cell Lung Cancer as a Strategy to Improve Clinical Outcome and Identify Early Mechanisms of Resistance |
Q38694837 | Neoadjuvant chemotherapy by bronchial arterial infusion in patients with unresectable stage III squamous cell lung cancer |
Q38185175 | Neoadjuvant therapy for localized prostate cancer: Examining mechanism of action and efficacy within the tumor |
Q47915799 | Neoantigens in the immuno-oncology space |
Q37603346 | Neratinib: an oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer |
Q33813119 | Network biomarkers, interaction networks and dynamical network biomarkers in respiratory diseases |
Q28677268 | Network-based drug discovery by integrating systems biology and computational technologies |
Q37579308 | Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells. |
Q55709770 | Neuropeptide G Protein-Coupled Receptors as Oncotargets. |
Q34483541 | Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotinib |
Q45268799 | Never-smoking nonsmall cell lung cancer as a separate entity: clinicopathologic features and survival |
Q92377401 | New Era for Next-Generation Sequencing in Japan |
Q39453653 | New Insight into microRNA Functions in Cancer: Oncogene-microRNA-Tumor Suppressor Gene Network. |
Q35088122 | New Response Evaluation Criteria in Solid Tumors (RECIST) guidelines for advanced non-small cell lung cancer: comparison with original RECIST and impact on assessment of tumor response to targeted therapy |
Q38947183 | New and emerging targeted treatments in advanced non-small-cell lung cancer. |
Q38163931 | New approach to cancer therapy based on a molecularly defined cancer classification. |
Q52646651 | New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing. |
Q36616537 | New drugs for the treatment of metastatic or refractory soft tissue sarcomas in children |
Q58769699 | New drugs in thoracic oncology: needs and knowledge - an online ERS Lung Cancer Assembly survey |
Q47159366 | New insights in non-small-cell lung cancer: circulating tumor cells and cell-free DNA. |
Q24680988 | New molecularly targeted therapies for lung cancer |
Q39139889 | New options in the management of intractable ALK(+) metastatic non-small-cell lung cancer |
Q34998576 | New prognostic factors and scoring system for patients with skeletal metastasis |
Q26775385 | New strategies in immunotherapy for non-small cell lung cancer |
Q37724947 | New strategies in personalized medicine for solid tumors: molecular markers and clinical trial designs |
Q37080517 | New strategies in squamous cell carcinoma of the lung: identification of tumor drivers to personalize therapy |
Q37853198 | New targeted therapies for gastric cancer |
Q42024692 | New targets and challenges in the molecular therapeutics of cancer |
Q37936432 | New targets and targeted drugs for the treatment of cancer: an outlook to pediatric oncology |
Q24806486 | New targets for therapy in breast cancer: small molecule tyrosine kinase inhibitors |
Q38114835 | New targets in non-small cell lung cancer |
Q38949133 | New therapeutic perspectives in CCDC6 deficient lung cancer cells |
Q26746230 | New treatment options for ALK+ advanced non-small-cell lung cancer: critical appraisal of ceritinib |
Q28067439 | Next generation sequencing techniques in liquid biopsy: focus on non-small cell lung cancer patients |
Q39114552 | Next-Generation EGFR Tyrosine Kinase Inhibitors for Treating EGFR-Mutant Lung Cancer beyond First Line |
Q28079320 | Next-generation EGFR/HER tyrosine kinase inhibitors for the treatment of patients with non-small-cell lung cancer harboring EGFR mutations: a review of the evidence |
Q35726787 | Next-generation sequencing for molecular diagnosis of lung adenocarcinoma specimens obtained by fine needle aspiration cytology |
Q35078128 | Next-generation sequencing of lung cancer EGFR exons 18-21 allows effective molecular diagnosis of small routine samples (cytology and biopsy). |
Q34657670 | Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants. |
Q60957062 | Nile Tilapia Derived TP4 Shows Broad Cytotoxicity Toward to Non-Small-Cell Lung Cancer Cells |
Q33779303 | Nimotuzumab plus chemotherapy versus chemotherapy alone in advanced non-small-cell lung cancer: a multicenter, randomized, open-label Phase II study |
Q39139857 | Nimotuzumab, a novel monoclonal antibody to the epidermal growth factor receptor, in the treatment of non-small cell lung cancer |
Q37558534 | Nimotuzumab: a novel anti-EGFR monoclonal antibody that retains anti-EGFR activity while minimizing skin toxicity |
Q34385995 | Nomogram Predicting Clinical Outcomes in Non-small Cell Lung Cancer Patients Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors |
Q90747070 | Non-Small Cell Lung Cancer in Countries of Central and Southeastern Europe: Diagnostic Procedures and Treatment Reimbursement Surveyed by the Central European Cooperative Oncology Group |
Q64244179 | Non-Smoking-Associated Lung Cancer: A distinct Entity in Terms of Tumor Biology, Patient Characteristics and Impact of Hereditary Cancer Predisposition |
Q28730066 | Non-antioxidant properties of α-tocopherol reduce the anticancer activity of several protein kinase inhibitors in vitro |
Q52716935 | Non-canonical functions of the RB protein in cancer. |
Q39163315 | Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment. |
Q100694461 | Non-invasive detection of EGFR mutations by cell-free loop-mediated isothermal amplification (CF-LAMP) |
Q36924440 | Non-small Cell Lung Cancer with Concomitant EGFR, KRAS, and ALK Mutation: Clinicopathologic Features of 12 Cases |
Q47146342 | Non-small cell lung cancer (NSCLC), EGFR downstream pathway activation and TKI targeted therapies sensitivity: Effect of the plasma membrane-associated NEU3. |
Q37874487 | Non-small cell lung cancer in never smokers as a representative 'non-smoking-associated lung cancer': epidemiology and clinical features |
Q37859221 | Non-small cell lung cancer in never-smokers: a new disease entity? |
Q47139758 | Non-small cell lung cancer treatment (r)evolution: ten years of advances and more to come. |
Q34558586 | Non-small cell lung cancer with EML4-ALK translocation in Chinese male never-smokers is characterized with early-onset |
Q26740333 | Non-small cell lung cancer: current treatment and future advances |
Q28278682 | Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship |
Q37645231 | Non-small cell lung cancer: the era of targeted therapy |
Q37692660 | Non-small-cell lung cancer harbouring mutations in the EGFR kinase domain |
Q36850900 | Non-small-cell lung cancer: molecular targeted therapy and personalized medicine - drug resistance, mechanisms, and strategies |
Q38233321 | Non-small-cell lung cancers: a heterogeneous set of diseases |
Q36622817 | Noncovalent wild-type-sparing inhibitors of EGFR T790M |
Q37321820 | Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: a phase II study. |
Q33735738 | Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer. |
Q33909660 | Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer. |
Q38865192 | Norcantharidin combined with EGFR-TKIs overcomes HGF-induced resistance to EGFR-TKIs in EGFR mutant lung cancer cells via inhibition of Met/PI3k/Akt pathway |
Q26744284 | Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy |
Q58790384 | Notch3-dependent β-catenin signaling mediates EGFR TKI drug persistence in EGFR mutant NSCLC |
Q38999795 | Novel [99mTcN]2+ labeled EGFR inhibitors as potential radiotracers for single photon emission computed tomography (SPECT) tumor imaging. |
Q34389263 | Novel agents in development for advanced non-small cell lung cancer |
Q46255077 | Novel and existing mutations in the tyrosine kinase domain of the epidermal growth factor receptor are predictors of optimal resectability in malignant peritoneal mesothelioma |
Q37923386 | Novel approaches to treating leptomeningeal metastases |
Q37772496 | Novel biomarkers of metastatic cancer |
Q38152899 | Novel cancer therapies: treatments driven by tumour biology |
Q39238873 | Novel dithiocarbamic acid esters derived from 6-aminomethyl-4-anilinoquinazolines and 6-aminomethyl-4-anilino-3-cyanoquinolines as potent EGFR inhibitors |
Q34158952 | Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations |
Q36612451 | Novel heteroduplex method using small cytology specimens with a remarkably high success rate for analysing EGFR gene mutations with a significant correlation to gefitinib efficacy in non-small-cell lung cancer |
Q28386773 | Novel insights into the molecular origins and treatment of lung cancer |
Q36045973 | Novel kinase inhibitors in renal cell carcinoma: progressive development of static agents |
Q82562299 | Novel kinase inhibitors in renal cell carcinoma: progressive development of static agents |
Q37702126 | Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma |
Q37038500 | Novel targets in non-small cell lung cancer: ROS1 and RET fusions |
Q36187046 | Novel therapeutics in adult malignant brain gliomas |
Q51707848 | Novel use for an EGFR mutation-specific antibody in discriminating lung adenocarcinoma from reactive pneumocyte hyperplasia. |
Q36864786 | Nuclear excision repair-based personalized therapy for non-small cell lung cancer: from hypothesis to reality |
Q36798851 | Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implications |
Q38810432 | Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival |
Q35063410 | Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells |
Q42431173 | Numerical indices based on circulating tumor DNA for the evaluation of therapeutic response and disease progression in lung cancer patients |
Q46073617 | O-Mel-Inib: a Cancéro-pôle Nord-Ouest multicenter phase II trial of high-dose imatinib mesylate in metastatic uveal melanoma. |
Q36530038 | Observation of hepatotoxicity during long-term gefitinib administration in patients with non-small-cell lung cancer |
Q41976220 | Occupy EGFR. |
Q50316870 | Octogenarians with EGFR-mutated non-small cell lung cancer treated by tyrosine-kinase inhibitor: a multicentric real-world study assessing tolerance and efficacy (OCTOMUT study). |
Q36108082 | Oligo-recurrence predicts favorable prognosis of brain-only oligometastases in patients with non-small cell lung cancer treated with stereotactic radiosurgery or stereotactic radiotherapy: a multi-institutional study of 61 subjects |
Q90349512 | Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors |
Q91761286 | Oligosaccharyltransferase: A Gatekeeper of Health and Tumor Progression |
Q37188017 | Omics and therapy - a basis for precision medicine |
Q91238291 | Onco-omics Approaches and Applications in Clinical Trials for Cancer Patients |
Q44945808 | Oncocytic, focally anaplastic, thyroid cancer responding to erlotinib |
Q38355156 | Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure |
Q35729391 | Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways |
Q33510334 | Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells |
Q36016428 | Oncogene status predicts patterns of metastatic spread in treatment-naive nonsmall cell lung cancer |
Q35623817 | Oncogenes come of age. |
Q41009749 | Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer. |
Q36337966 | Oncogenic PI3K deregulates transcription and translation |
Q27852800 | Oncogenic RIT1 mutations in lung adenocarcinoma |
Q33902463 | Oncogenic activity of epidermal growth factor receptor kinase mutant alleles is enhanced by the T790M drug resistance mutation |
Q45916835 | Oncogenic driver mutations in patients with non-small-cell lung cancer at various clinical stages. |
Q47147399 | Oncogenic driver mutations, treatment, and EGFR-TKI resistance in a Caucasian population with non-small cell lung cancer: survival in clinical practice |
Q38213830 | Oncogenic drivers, targeted therapies, and acquired resistance in non-small-cell lung cancer |
Q33943421 | Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy |
Q34073766 | Oncogenic mutations are associated with histological subtypes but do not have an independent prognostic value in lung adenocarcinoma |
Q24321210 | Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization |
Q24810573 | Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants |
Q37295261 | Oncologist's/haematologist's view on the roles of pathologists for molecular targeted cancer therapy |
Q37782592 | Oncomutations as biomarkers of cancer risk. |
Q37069689 | Opportunities and challenges in the era of molecularly targeted agents and radiation therapy |
Q38520010 | Opportunities and challenges in using studies without a control group in comparative effectiveness reviews |
Q36883671 | Optimal duration of chemotherapy in advanced non-small cell lung cancer |
Q37822780 | Optimal management of patients with non-small cell lung cancer and epidermal growth factor receptor mutations |
Q26859993 | Optimal therapeutic strategy for non-small cell lung cancer with mutated epidermal growth factor receptor |
Q36406541 | Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling |
Q37756959 | Optimization of genetics to create therapies for metastatic (stage IV) non-small-cell lung cancer |
Q38405477 | Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of KRAS, PIK3CA, MET, and non-sensitizing EGFR mutations |
Q36354945 | Optimized expression-based microdissection of formalin-fixed lung cancer tissue. |
Q36430307 | Optimizing chemotherapy and targeted agent combinations in NSCLC. |
Q53088478 | Optimizing endobronchial ultrasound for molecular analysis. How many passes are needed? |
Q36441490 | Optimizing response to gefitinib in the treatment of non-small-cell lung cancer |
Q35112467 | Optimizing the sequence of anti-EGFR-targeted therapy in EGFR-mutant lung cancer |
Q39128273 | Optimizing treatment for patients with anaplastic lymphoma kinase-positive lung cancer |
Q37996453 | Oral tyrosine kinase inhibitors in the first-line treatment of advanced non-small cell lung cancer |
Q28652806 | Organizing knowledge to enable personalization of medicine in cancer |
Q28083032 | Organoid development in cancer genome discovery |
Q47131461 | Organotypic three-dimensional cancer cell cultures mirror drug responses in vivo: lessons learned from the inhibition of EGFR signaling. |
Q54213250 | Osimertinib Western and Asian clinical pharmacokinetics in patients and healthy volunteers: implications for formulation, dose, and dosing frequency in pivotal clinical studies. |
Q38790929 | Osimertinib for EGFR T790M mutation-positive non-small cell lung cancer |
Q39002726 | Osimertinib for the treatment of non-small cell lung cancer |
Q33757134 | Osimertinib in patients with advanced epidermal growth factor receptor T790M mutation-positive non-small cell lung cancer: rationale, evidence and place in therapy |
Q38598893 | Osimertinib in the treatment of non-small-cell lung cancer: design, development and place in therapy |
Q38991958 | Osimertinib in the treatment of patients with epidermal growth factor receptor T790M mutation-positive metastatic non-small cell lung cancer: clinical trial evidence and experience |
Q54959395 | Osimertinib in untreated epidermal growth factor receptor (EGFR)-mutated advanced non-small cell lung cancer. |
Q35368205 | Our changing view of the genomic landscape of cancer |
Q35584972 | Outcomes after combined modality therapy for EGFR-mutant and wild-type locally advanced NSCLC. |
Q51317673 | Outcomes of Malaysian patients with advanced lung adenocarcinoma and unknown epidermal growth factor receptor mutation status treated with gefitinib. |
Q50122983 | Outcomes of an Australian testing programme for epidermal growth factor receptor mutations in non-small cell lung cancer. |
Q45936261 | Outpacing cancer. |
Q38040628 | Ovarian cancer: advances in first-line treatment strategies with a particular focus on anti-angiogenic agents. |
Q81578551 | Ovarian granulosa cell tumors frequently express EGFR (Her-1), Her-3, and Her-4: An immunohistochemical study |
Q36750945 | Overall survival benefits of first-line EGFR tyrosine kinase inhibitors in EGFR-mutated non-small-cell lung cancers: a systematic review and meta-analysis. |
Q37057914 | Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors |
Q58599659 | Overcoming EGFR-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors |
Q42716087 | Overcoming erlotinib resistance with tailored treatment regimen in patient-derived xenografts from naïve Asian NSCLC patients |
Q40996325 | Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma |
Q26745427 | Overcoming resistance to first/second generation epidermal growth factor receptor tyrosine kinase inhibitors and ALK inhibitors in oncogene-addicted advanced non-small cell lung cancer |
Q36812355 | Overcoming resistance to molecularly targeted anticancer therapies: Rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies |
Q26795556 | Overcoming resistance to targeted therapies in NSCLC: current approaches and clinical application |
Q37357692 | Overcoming resistance to tyrosine kinase inhibitors: lessons learned from cancer cells treated with EGFR antagonists |
Q48301559 | Overexpression of ATP-Binding Cassette Subfamily G Member 2 Confers Resistance to Phosphatidylinositol 3-Kinase Inhibitor PF-4989216 in Cancer Cells. |
Q24678516 | Overexpression of PIAS3 suppresses cell growth and restores the drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivation |
Q36615322 | Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability |
Q37619679 | Overexpression of mutant EGFR protein indicates a better survival benefit from EGFR-TKI therapy in non-small cell lung cancer |
Q37157333 | Overview of chemoradiation clinical trials for locally advanced non-small cell lung cancer in Japan |
Q37579644 | Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors. |
Q35763328 | Overview of the development of personalized genomic medicine and surgery |
Q36690248 | Overview of the pharmacoeconomics of pharmacogenetics |
Q86506613 | PCR-sequencing is a complementary method to amplification refractory mutation system for EGFR gene mutation analysis in FFPE samples |
Q37013280 | PD-1/PD-L1 expression in non-small-cell lung cancer and its correlation with EGFR/KRAS mutations |
Q47124504 | PD-L1 promoter methylation mediates the resistance response to anti-PD-1 therapy in NSCLC patients with EGFR-TKI resistance |
Q42942636 | PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor |
Q50326521 | PET Imaging-Based Phenotyping as a Predictive Biomarker of Response to Tyrosine Kinase Inhibitor Therapy in Non-small Cell Lung Cancer: Are We There Yet? |
Q35653992 | PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer. |
Q37039348 | PI3K signaling in glioma--animal models and therapeutic challenges |
Q35808438 | PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations |
Q34028766 | PIK3CA and KRAS mutations predict for response to everolimus therapy: now that’s RAD001 |
Q36545534 | PIK3CA mutation detection in metastatic biliary cancer using cell-free DNA |
Q54360869 | PIK3CA mutation is an early event in the development of endometriosis-associated ovarian clear cell adenocarcinoma. |
Q38584695 | PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab |
Q34616536 | PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells |
Q33987852 | PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers |
Q39826662 | PKC-delta binds to E-cadherin and mediates EGF-induced cell scattering |
Q38087648 | PROFILing non-small-cell lung cancer patients for treatment with crizotinib according to anaplastic lymphoma kinase abnormalities: translating science into medicine. |
Q38732488 | PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis |
Q38629644 | PTEN and PI3K/AKT in non-small-cell lung cancer. |
Q44846498 | PTEN and PIK3CA expression is associated with prolonged survival after gefitinib treatment in EGFR-mutated lung cancer patients. |
Q39398876 | PTMScan direct: identification and quantification of peptides from critical signaling proteins by immunoaffinity enrichment coupled with LC-MS/MS. |
Q36788450 | Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer |
Q36487089 | Paclitaxel-carboplatin combination chemotherapy in advanced breast cancer: accumulating evidence for synergy, efficacy, and safety |
Q36900261 | Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer |
Q37398845 | Parameters for individualizing systemic therapy in non-small cell lung cancer |
Q35584647 | Part 4: pharmacogenetic variability in anticancer pharmacodynamic drug effects |
Q88790399 | Past, present and future of gene expression-tailored therapy for lung cancer |
Q37389526 | Pathogenesis of lung cancer signalling pathways: roadmap for therapies |
Q36233709 | Pathogenesis of lung cancer: 100 year report |
Q34781357 | Pathways driving the endocytosis of mutant and wild-type EGFR in cancer |
Q44507827 | Patient harboring a novel PIK3CA point mutation after acquired resistance to crizotinib in an adenocarcinoma with ROS1 rearrangement: A case report and literature review |
Q47895107 | Patient selection criteria and the FLEX Study |
Q40340984 | Patient selection in non-small cell lung cancer: Histologic versus molecular subtypes? |
Q28080046 | Patient-derived tumour xenografts for breast cancer drug discovery |
Q39377749 | Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors |
Q64267035 | Pattern of recurrence after CyberKnife stereotactic body radiotherapy for peripheral early non-small cell lung cancer |
Q93136766 | Patterns of brain metastasis in anaplastic lymphoma kinase - rearranged and epidermal growth factor receptor-mutated lung cancer patients in magnetic resonance imaging |
Q36334789 | Patterns of epidermal growth factor receptor mutation in non-small-cell lung cancers in the Gulf region |
Q41559395 | Patterns of spread and prognostic implications of lung cancer metastasis in an era of driver mutations. |
Q48322740 | Paul Ehrlich's magic bullet concept: 100 years of progress |
Q36273006 | Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches |
Q80671770 | Pediatric oncology |
Q36187075 | Pemetrexed Singlet Versus Nonpemetrexed-Based Platinum Doublet as Second-Line Chemotherapy after First-Line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Failure in Non-small Cell Lung Cancer Patients with EGFR Mutations |
Q47952924 | Pemetrexed monotherapy for chemo-naïve elderly (aged ≥80) patients with non-squamous non-small cell lung cancer: results from combined analysis of two single arm phase II studies (HANSHIN002 and 003). |
Q55070748 | Pemetrexed-based chemotherapy in advanced lung adenocarcinoma patients with different EGFR genotypes. |
Q36187118 | Peptide Nucleic Acid Clamping Versus Direct Sequencing for the Detection of EGFR Gene Mutation in Patients with Non-small Cell Lung Cancer |
Q40013710 | Peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based detection test for gefitinib-refractory T790M epidermal growth factor receptor mutation. |
Q38176989 | Peptide nucleic acids: a review on recent patents and technology transfer |
Q33520512 | Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications |
Q53338991 | Percutaneous computed tomography-guided lung biopsy and pleural dissemination: an assessment by intraoperative pleural lavage cytology. |
Q46862765 | Percutaneous image-guided biopsy of prostate cancer metastases yields samples suitable for genomics and personalised oncology |
Q34235130 | Performance of standard procedures in detection of EGFR mutations in daily practice in advanced NSCLC patients selected according to the ESMO guideline: a large Caucasian cohort study |
Q36462861 | Perimembrane Aurora-A expression is a significant prognostic factor in correlation with proliferative activity in non-small-cell lung cancer (NSCLC). |
Q40479158 | Peroxisome proliferator-activated receptor-gamma (PPAR(gamma)) inhibits tumorigenesis by reversing the undifferentiated phenotype of metastatic non-small-cell lung cancer cells (NSCLC). |
Q64354468 | Personalised Medicine: The Odyssey from Hope to Practice |
Q36089579 | Personalized Combined Modality Therapy for Locally Advanced Non-small Cell Lung Cancer |
Q39453553 | Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies |
Q37965048 | Personalized cancer medicine and the future of pathology. |
Q38976521 | Personalized learning: From neurogenetics of behaviors to designing optimal language training |
Q37651778 | Personalized management of chronic obstructive pulmonary disease via transcriptomic profiling of the airway and lung. |
Q36441548 | Personalized medicine and treatment approaches in non-small-cell lung carcinoma |
Q37932029 | Personalized medicine for lung cancer: new challenges for pathology |
Q35757107 | Personalized medicine for pathological circadian dysfunctions |
Q36817080 | Personalized medicine for targeted and platinum-based chemotherapy of lung and bladder cancer |
Q35680026 | Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative |
Q37921595 | Personalized medicine in lung cancer: what we need to know. |
Q57177486 | Personalized medicine in non-small cell lung cancer: a review from a pharmacogenomics perspective |
Q51828510 | Personalized medicine in oncology: the future is now. |
Q74441598 | Personalized medicine: Special treatment |
Q42697296 | Personalized medicine: hype or reality |
Q38232150 | Personalized oncology: genomic screening in phase 1. |
Q37214412 | Personalized prediction of EGFR mutation-induced drug resistance in lung cancer. |
Q27027259 | Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014 |
Q36321826 | Personalized targeted therapy for lung cancer |
Q58792324 | Personalized therapy for lung cancer: Striking a moving target |
Q37996505 | Personalized therapy for non-small cell lung cancer: which drug for which patient? |
Q35911350 | Personalized therapy in endometrial cancer: challenges and opportunities |
Q38266308 | Personalized treatment of EGFR mutant and ALK-positive patients in NSCLC. |
Q28075800 | Personalized treatment of advanced non-small-cell lung cancer in routine clinical practice |
Q36015295 | Personalized tumor response assessment in the era of molecular medicine: cancer-specific and therapy-specific response criteria to complement pitfalls of RECIST |
Q27851614 | Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer |
Q37080513 | Personalizing lung cancer prevention through a reverse migration strategy |
Q36811453 | Personalizing therapy in advanced non-small cell lung cancer |
Q35679361 | Personalizing therapy with targeted agents in non-small cell lung cancer |
Q47240432 | Perspective: The clinical trial barriers |
Q43061648 | Perspectives in adjuvant chemotherapy in NSCLC. |
Q36163982 | Perspectives on novel therapies for bronchial carcinoma |
Q39940683 | Perspectives on the development of imatinib and the future of cancer research |
Q28537769 | Perturbation biology: inferring signaling networks in cellular systems |
Q24339394 | Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms |
Q34042708 | Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity |
Q28382921 | PharmGKB summary: very important pharmacogene information for the epidermal growth factor receptor |
Q28278381 | Pharmacodynamic biomarkers for molecular cancer therapeutics |
Q37194753 | Pharmacoeconomic evaluations of pharmacogenetic and genomic screening programmes: a systematic review on content and adherence to guidelines |
Q35889619 | Pharmacogenetics - five decades of therapeutic lessons from genetic diversity |
Q35889605 | Pharmacogenetics and drug development: the path to safer and more effective drugs |
Q40218486 | Pharmacogenetics and stomach cancer: an update. |
Q36478845 | Pharmacogenetics approach to therapeutics |
Q35038056 | Pharmacogenetics in drug development |
Q37275470 | Pharmacogenetics in drug discovery and development: a translational perspective |
Q36256445 | Pharmacogenetics in gastrointestinal tumors |
Q36493347 | Pharmacogenetics in the management of breast cancer -- prospects for individualised treatment. |
Q35840645 | Pharmacogenetics in type 2 diabetes: potential implications for clinical practice |
Q38010747 | Pharmacogenetics of EGFR in lung cancer: perspectives and clinical applications |
Q23919667 | Pharmacogenetics, pharmacogenomics, and individualized medicine |
Q36294685 | Pharmacogenetics/genomics and personalized medicine |
Q37430384 | Pharmacogenetics: implementing personalized medicine |
Q38262008 | Pharmacogenomic biomarkers for personalized cancer treatment. |
Q28392982 | Pharmacogenomic discovery using cell-based models |
Q35873676 | Pharmacogenomics and stomach cancer. |
Q38596926 | Pharmacogenomics in the treatment of lung cancer: an update |
Q27025558 | Pharmacogenomics of chemotherapeutic susceptibility and toxicity |
Q36966043 | Pharmacogenomics of lung cancer: with a view to address EGFR-targeted therapies |
Q56446183 | Pharmacogenomics steps toward personalized medicine |
Q35876017 | Pharmacogenomics: bench to bedside |
Q36658763 | Pharmacogenomics: challenges and opportunities |
Q36465177 | Pharmacogenomics: from bedside to clinical practice |
Q37353853 | Pharmacokinetic considerations for new targeted therapies. |
Q46375104 | Pharmacokinetics of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, in rat and dog. |
Q37492540 | Pharmacologic and chemical adjuvants in tumor virotherapy |
Q39396274 | Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells. |
Q37822760 | Pharmacometabonomics as an effector for personalized medicine. |
Q38248997 | Pharmacotherapy targeting the EGFR oncogene in NSCLC. |
Q33161299 | Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib |
Q53545682 | Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer. |
Q49962860 | Phase 1b Trial of Ficlatuzumab, a Humanized Hepatocyte Growth Factor Inhibitory Monoclonal Antibody, in Combination With Gefitinib in Asian Patients With NSCLC. |
Q45904308 | Phase 2 trial of afatinib, an ErbB family blocker, in solid tumors genetically screened for target activation. |
Q37069238 | Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma. |
Q50933613 | Phase I study of 5-aza-2'-deoxycytidine in combination with valproic acid in non-small-cell lung cancer. |
Q91796969 | Phase I study of TAS-121, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, in patients with non-small-cell lung cancer harboring EGFR mutations |
Q36317627 | Phase I study of icotinib, an EGFR tyrosine kinase inhibitor combined with IMRT in nasopharyngeal carcinoma |
Q35527148 | Phase I study of irinotecan and gefitinib in patients with gefitinib treatment failure for non-small cell lung cancer |
Q43092698 | Phase I trial of liposomal doxorubicin and ZD1839 in patients with refractory gynecological malignancies or metastatic breast cancer |
Q34549722 | Phase I trial of oxaliplatin, infusional 5-fluorouracil, and leucovorin (FOLFOX4) with erlotinib and bevacizumab in colorectal cancer |
Q36938818 | Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. |
Q34578584 | Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer |
Q64107367 | Phase II Trial of Cabozantinib Plus Erlotinib in Patients With Advanced Epidermal Growth Factor Receptor ()-Mutant Non-small Cell Lung Cancer With Progressive Disease on Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy: A California |
Q37705422 | Phase II clinical trials in oncology: are we hitting the target? |
Q42162257 | Phase II randomized study of daily gefitinib treatment alone or with vinorelbine every 2 weeks in patients with adenocarcinoma of the lung who failed at least 2 regimens of chemotherapy |
Q33390208 | Phase II study of S-1, a novel oral fluoropyrimidine, and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer |
Q36614114 | Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer |
Q52941341 | Phase II study of erlotinib in elderly patients with non-small cell lung cancer harboring epidermal growth factor receptor mutations. |
Q44656784 | Phase II study of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer |
Q34427320 | Phase II study of pemetrexed and carboplatin plus bevacizumab, followed by maintenance pemetrexed and bevacizumab in Japanese patients with non-squamous non-small cell lung cancer |
Q37693919 | Phase II trial of dose-dense chemotherapy followed by dose-intense erlotinib for patients with newly diagnosed metastatic non-small cell lung cancer |
Q54403335 | Phase II trial of erlotinib in patients with advanced non‑small‑cell lung cancer harboring epidermal growth factor receptor mutations: additive analysis of pharmacokinetics. |
Q36625206 | Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer |
Q33608491 | Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer |
Q51493357 | Phase II trial of gefitinib in pretreated Chinese women with advanced non-small-cell lung cancer. |
Q46791717 | Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers. |
Q35208151 | Phase II trial of modified FOLFOX6 and erlotinib in patients with metastatic or advanced adenocarcinoma of the oesophagus and gastro-oesophageal junction |
Q42663635 | Phase III, randomized, open-label, first-line study in Asia of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer: evaluation of patients recruited from mainland China. |
Q37414810 | Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study |
Q47723850 | Phase1 study of cisplatin plus pemetrexed with erlotinib and bevacizumab for chemotherapy-naïve advanced non-squamous non-small cell lung cancer with EGFR mutations |
Q94545721 | Phenotypic screening using large-scale genomic libraries to identify drug targets for the treatment of cancer |
Q35256618 | Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway in non-small cell lung cancer |
Q36642695 | Phosphatidylinositol-3-kinase α catalytic subunit gene somatic mutations in bronchopulmonary neuroendocrine tumours |
Q36346828 | Phosphoinositide 3-kinase: from viral oncoprotein to drug target |
Q38757884 | Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer. |
Q36219744 | Phosphoproteomics for oncology discovery and treatment |
Q34539788 | Phosphoproteomics in cancer |
Q27851872 | Phosphorylated EGFR expression may predict outcome of EGFR-TKIs therapy for the advanced NSCLC patients with wild-type EGFR |
Q36717778 | Phosphorylated epidermal growth factor receptor and cyclooxygenase-2 expression in localized non-small cell lung cancer |
Q35082185 | Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors |
Q24644787 | Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors |
Q39561256 | Phosphorylated insulin-like growth factor 1 receptor is implicated in resistance to the cytostatic effect of gefitinib in colorectal cancer cells |
Q34598322 | Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation. |
Q54503313 | Phosphorylation of epidermal growth factor receptor and chromosome 7 polysomy in gastric adenocarcinoma. |
Q38943113 | Phosphotyrosine profiling identifies ephrin receptor A2 as a potential therapeutic target in esophageal squamous-cell carcinoma. |
Q36524232 | Photodynamic therapy activated signaling from epidermal growth factor receptor and STAT3: Targeting survival pathways to increase PDT efficacy in ovarian and lung cancer |
Q36962642 | Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling |
Q34039413 | Physicochemical properties of epidermal growth factor receptor inhibitors and development of a nanoliposomal formulation of gefitinib |
Q47387077 | Physiologically Based Pharmacokinetic Modeling to Evaluate the Systemic Exposure of Gefitinib in CYP2D6 Ultrarapid Metabolizers and Extensive Metabolizers |
Q36558400 | Picoliter-Droplet Digital Polymerase Chain Reaction-Based Analysis of Cell-Free Plasma DNA to Assess EGFR Mutations in Lung Adenocarcinoma That Confer Resistance to Tyrosine-Kinase Inhibitors |
Q39089524 | Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors |
Q35187806 | Pilot study of gefitinib and fulvestrant in the treatment of post-menopausal women with advanced non-small cell lung cancer |
Q42835389 | Pitfalls in immunohistochemical assessment of EGFR expression in soft tissue sarcomas |
Q35996716 | Pituitary adenylate cyclase-activating polypeptide causes tyrosine phosphorylation of the epidermal growth factor receptor in lung cancer cells |
Q54961209 | Pituitary-Directed Therapies for Cushing's Disease. |
Q45998326 | Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor. |
Q51239492 | Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance? |
Q36020891 | Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity |
Q36632245 | Point mutations of protein kinases and individualised cancer therapy |
Q51415798 | Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma. |
Q36385082 | Polymorphisms in intron 1 of the EGFR gene in non-small cell lung cancer patients |
Q28757672 | Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers |
Q35800638 | Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma. |
Q37623532 | Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations |
Q51029938 | Pooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy. |
Q34311186 | Pooled analysis of clinical outcome for EGFR TKI-treated patients with EGFR mutation-positive NSCLC |
Q36905639 | Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers |
Q89493481 | Poor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer |
Q37528486 | Poor response to erlotinib in patients with tumors containing baseline EGFR T790M mutations found by routine clinical molecular testing. |
Q42340129 | Poor response to platinum-based chemotherapy is associated with KRAS mutation and concomitant low expression of BRAC1 and TYMS in NSCLC. |
Q43515674 | Population pharmacokinetics/pharmacodynamics of erlotinib and pharmacogenomic analysis of plasma and cerebrospinal fluid drug concentrations in Japanese patients with non-small cell lung cancer |
Q28394485 | Population-based trends in lung cancer incidence in women |
Q26778987 | Positional proteomics in the era of the human proteome project on the doorstep of precision medicine |
Q36420719 | Positron emission tomography measurement of tumor metabolism and growth: its expanding role in oncology |
Q27026940 | Positron emission tomography to assess hypoxia and perfusion in lung cancer |
Q36439506 | Positron emission tomography-computed tomography on predicting the efficacy of targeted therapy for lung adenocarcinoma |
Q99565904 | Postoperative management for non-small cell lung cancer harboring EGFR mutations |
Q95723908 | Postoperative survival According to the Glasgow Prognostic Score in Patients with Resected Lung Adenocarcinoma |
Q36537788 | Posttranslational protein modifications: current implications for cancer detection, prevention, and therapeutics |
Q35941562 | Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model. |
Q26775315 | Potential targets for ovarian clear cell carcinoma: a review of updates and future perspectives |
Q33520624 | Power to detect selective allelic amplification in genome-wide scans of tumor data |
Q38555223 | Practical Value of Molecular Pathology in Stage I-III Lung Cancer: Implications for the Clinical Surgeon |
Q47597667 | Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics |
Q89429141 | Pragmatic approaches to address expansion cohort design |
Q35702897 | Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome. |
Q89975407 | Precision Medicine Tumor Boards: Clinical Applicability of Personalized Treatment Concepts in Ovarian Cancer |
Q33714064 | Precision Medicine: The New Frontier in Idiopathic Pulmonary Fibrosis |
Q38838757 | Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment |
Q50195535 | Precision Oncology: The Road Ahead. |
Q38810911 | Precision medicine in pediatric oncology: Lessons learned and next steps |
Q47566249 | Precision medicine: does ethnicity information complement genotype-based prescribing decisions? |
Q52857191 | Preclinical Study of a Combination of Erlotinib and Bevacizumab in Early Stages of Unselected Non-Small Cell Lung Cancer Patient-Derived Xenografts. |
Q40373819 | Preclinical evaluation of ZD1839 alone or in combination with oxaliplatin in a panel of human tumor cell lines -- implications for clinical use. |
Q27322080 | Preclinical mouse cancer models: a maze of opportunities and challenges |
Q40365247 | Preclinical study of a "tailor-made" combination of NK4-expressing gene therapy and gefitinib (ZD1839, Iressa) for disseminated peritoneal scirrhous gastric cancer |
Q36547786 | Predicting clinical benefit in non-small-cell lung cancer patients treated with epidermal growth factor tyrosine kinase inhibitors |
Q37209222 | Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions |
Q34572279 | Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia |
Q36788485 | Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer. |
Q36042375 | Predicting survival of patients with resectable non-small cell lung cancer: Beyond TNM |
Q33247966 | Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development |
Q35151544 | Prediction and prioritization of rare oncogenic mutations in the cancer Kinome using novel features and multiple classifiers |
Q40053178 | Prediction of EGFR and KRAS mutation in non-small cell lung cancer using quantitative 18F FDG-PET/CT metrics |
Q40327150 | Prediction of anticancer drug potency from expression of genes involved in growth factor signaling |
Q43162278 | Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer |
Q45248889 | Prediction of response to tyrosine kinase epithelial cell growth factor receptor inhibitors: a major breakthrough in the treatment of non-small-cell lung cancer |
Q45116933 | Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839). |
Q51743342 | Prediction of sensitivity to gefitinib/erlotinib for EGFR mutations in NSCLC based on structural interaction fingerprints and multilinear principal component analysis. |
Q57896476 | Predictive Tumor Biomarkers for EGFR Inhibitors |
Q34620545 | Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: a systemic review of current development, evidence, and recommendation |
Q35076206 | Predictive and prognostic markers for epidermal growth factor receptor inhibitor therapy in non-small cell lung cancer |
Q33311133 | Predictive and prognostic markers in neuro-oncology |
Q38137764 | Predictive biomarkers for cancer therapy with PARP inhibitors. |
Q26824536 | Predictive biomarkers in precision medicine and drug development against lung cancer |
Q46066416 | Predictive biomarkers in the development of oncology drugs: a therapeutic industry perspective. |
Q52991200 | Predictive efficacy of (11)C-PD153035 PET imaging for EGFR-tyrosine kinase inhibitor sensitivity in non-small cell lung cancer patients. |
Q35077521 | Predictive efficacy of low burden EGFR mutation detected by next-generation sequencing on response to EGFR tyrosine kinase inhibitors in non-small-cell lung carcinoma |
Q36610291 | Predictive factors associated with prolonged survival in patients with advanced non-small-cell lung cancer (NSCLC) treated with gefitinib |
Q35773852 | Predictive factors for epidermal growth factor receptor inhibitors--the bull's-eye hits the arrow |
Q34427439 | Predictive factors in patients with EGFR mutation-negative non-small cell lung cancer treated with erlotinib |
Q39028004 | Predictive factors of early distant brain failure after gamma knife radiosurgery alone in patients with brain metastases of non-small-cell lung cancer |
Q37579647 | Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer |
Q54510031 | Predictive value of loci in VEGF pathway genes in bevacizumab treatment. |
Q47143835 | Predictors of EGFR mutation and factors associated with clinical tumor stage at diagnosis: Experience of the INSIGHT study in Poland. |
Q36808416 | Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study |
Q81601035 | Predominance of high-grade pathway in breast cancer development of Middle East women |
Q35145369 | Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma |
Q94371037 | Preface |
Q36088722 | Preliminary Evidence on the Diagnostic and Molecular Role of Circulating Soluble EGFR in Non-Small Cell Lung Cancer |
Q30890447 | Preparation of EGFR monoclonal antibody conjugated nanoparticles and targeting to hepatocellular carcinoma |
Q41869566 | Presence of EGFR mutation in pathologically non-malignant specimens from computed tomography-guided lung needle biopsies |
Q51168062 | Presence of pleural effusion is associated with a poor prognosis in patients with epidermal growth factor receptor-mutated lung cancer receiving tyrosine kinase inhibitors as first-line treatment. |
Q35877737 | Present status and problems on molecular targeted therapy of cancer |
Q35478632 | Pretreatment levels of the serum biomarkers CEA, CYFRA 21-1, SCC and the soluble EGFR and its ligands EGF, TGF-alpha, HB-EGF in the prediction of outcome in erlotinib treated non-small-cell lung cancer patients |
Q35671830 | Prevalence and Clinicopathological Characteristics of HER2 and BRAF Mutation in Chinese Patients with Lung Adenocarcinoma |
Q45370579 | Prevalence and detection of low-allele-fraction variants in clinical cancer samples. |
Q36330709 | Prevalence and outcome of epidermal growth factor receptor mutations in non-squamous non-small cell lung cancer patients |
Q38661269 | Prevalence of EGFR Mutations in Lung Cancer in Uruguayan Population |
Q39073840 | Prevalence of EGFR Tyrosine Kinase Domain Mutations in Head and Neck Squamous Cell Carcinoma: Cohort Study and Systematic Review |
Q41461334 | Prevalence of EGFR and ALK Mutations in Lung Adenocarcinomas in the Levant Area - a Prospective Analysis |
Q36085837 | Prevalence of KRAS, BRAF, PI3K and EGFR mutations among Asian patients with metastatic colorectal cancer |
Q60949785 | Prevalence of ROS1 fusion in Chinese patients with non-small cell lung cancer |
Q92107648 | Prevalence of the epidermal growth factor receptor mutations in lung adenocarcinoma patients from the Middle East region |
Q54384637 | Prevalence, clinicopathologic characteristics, and molecular associations of EGFR exon 20 insertion mutations in East Asian patients with lung adenocarcinoma. |
Q36654338 | Prevention of breast cancer: current state of the science and future opportunities |
Q38745430 | Primary Double-Strike Therapy for Cancers to Overcome EGFR Kinase Inhibitor Resistance: Proposal from the Bench |
Q38008698 | Primary and acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: an update |
Q37799825 | Primary and secondary therapeutic strategies for EGF receptor pathway inhibition in non-small-cell lung cancer |
Q27009148 | Primary chemotherapy and radiation as a treatment strategy for HPV-positive oropharyngeal cancer |
Q39649266 | Primary pulmonary lymphoepithelioma-like carcinoma: fifty-two patients with long-term follow-up |
Q36180606 | Priorities and standards in pharmacogenetic research |
Q43259078 | Prioritizing molecular markers to test for in the initial workup of advanced non-small cell lung cancer: wants versus needs |
Q38262620 | Prioritizing targets for precision cancer medicine |
Q38694064 | Pro-tumoural CXCL10/CXCR3-A autocrine loop in invasive mucinous lung adenocarcinoma. |
Q38470647 | ProKinO: a unified resource for mining the cancer kinome |
Q92282893 | Profile of Daniel A. Haber |
Q39106800 | Profile of the Roche cobas® EGFR mutation test v2 for non-small cell lung cancer. |
Q51139197 | Profile of the therascreen® EGFR RGQ PCR kit as a companion diagnostic for gefitinib in non-small cell lung cancer. |
Q21562343 | Profiling critical cancer gene mutations in clinical tumor samples |
Q92767063 | Profiling of protein-protein interactions via single-molecule techniques predicts the dependence of cancers on growth-factor receptors |
Q37652622 | Prognosis of recurrent non-small cell lung cancer following complete resection |
Q91906497 | Prognostic analysis of patients with mutant and wild-type EGFR gene lung adenocarcinoma |
Q38089884 | Prognostic and predictive factors in resected non-small-cell lung cancer |
Q34443983 | Prognostic and predictive role of the VeriStrat plasma test in patients with advanced non-small-cell lung cancer treated with erlotinib or placebo in the NCIC Clinical Trials Group BR.21 trial |
Q38019976 | Prognostic and predictive value of K-RAS mutations in non-small cell lung cancer |
Q38493294 | Prognostic and predictive value of MET deregulation in non-small cell lung cancer |
Q30498101 | Prognostic and predictive value of epidermal growth factor receptor tyrosine kinase domain mutation status and gene copy number for adjuvant chemotherapy in non-small cell lung cancer |
Q54632156 | Prognostic and predictive values of pERK1/2 and pAkt-1 expression in non-small cell lung cancer patients treated with adjuvant chemotherapy. |
Q33620091 | Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status |
Q34616626 | Prognostic effect of epidermal growth factor receptor gene mutations and the aberrant phosphorylation of Akt and ERK in ovarian cancer |
Q48551119 | Prognostic factors for brain metastases from non-small cell lung cancer with EGFR mutation: influence of stable extracranial disease and erlotinib therapy. |
Q44462744 | Prognostic factors for gefitinib-treated postoperative recurrence in non-small cell lung cancer |
Q55035103 | Prognostic factors of afatinib as a first-line therapy for advanced EGFR mutation-positive lung adenocarcinoma: a real-world, large cohort study. |
Q37702165 | Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial |
Q34544677 | Prognostic impact of [18F]fluorothymidine and [18F]fluoro-D-glucose baseline uptakes in patients with lung cancer treated first-line with erlotinib. |
Q38399545 | Prognostic impact of a new score using neutrophil-to-lymphocyte ratios in the serum and malignant pleural effusion in lung cancer patients |
Q36399028 | Prognostic impact of initial maximum standardized uptake value of (18)F-FDG PET/CT on treatment response in patients with metastatic lung adenocarcinoma treated with erlotinib |
Q34860000 | Prognostic impact of serum CYFRA 21-1 in patients with advanced lung adenocarcinoma: a retrospective study |
Q46620066 | Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma |
Q46416422 | Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma |
Q35681087 | Prognostic role of p53 and Ki-67 immunohistochemical expression in patients with surgically resected lung adenocarcinoma: a retrospective study |
Q34775815 | Prognostic significance of PIK3CA and SOX2 in Asian patients with lung squamous cell carcinoma |
Q34181641 | Prognostic significance of adenocarcinoma in situ, minimally invasive adenocarcinoma, and nonmucinous lepidic predominant invasive adenocarcinoma of the lung in patients with stage I disease |
Q45751366 | Prognostic significance of expression of cyclooxygenase-2, vascular endothelial growth factor, and epidermal growth factor receptor in nasopharyngeal carcinoma. |
Q54485965 | Prognostic significance of the IASLC/ATS/ERS classification in Chinese patients-A single institution retrospective study of 292 lung adenocarcinoma. |
Q90087574 | Prognostic value of EGFR 19-del and 21-L858R mutations in patients with non-small cell lung cancer |
Q34937417 | Prognostic value of EGFR mutation and ERCC1 in patients with non-small cell lung cancer undergoing platinum-based chemotherapy |
Q51678342 | Prognostic value of EGFR mutations in surgically resected pathological stage I lung adenocarcinoma. |
Q41296140 | Prognostic value of LIPC in non-small cell lung carcinoma |
Q47547523 | Prognostic value of epidermal growth factor receptor mutations and histologic subtypes with lung adenocarcinoma. |
Q46757816 | Prognostic value of epidermal growth factor receptor mutations in resected lung adenocarcinomas |
Q27692669 | Prognostic value of epidermal growth factor receptor mutations in resected non-small cell lung cancer: a systematic review with meta-analysis |
Q37902246 | Prognostic, therapeutic and diagnostic potential of microRNAs in non-small cell lung cancer |
Q49163406 | Programmed death-ligand 1 expression according to epidermal growth factor receptor mutation status in pretreated non-small cell lung cancer. |
Q35632548 | Progression-free Survival Decreases with Each Subsequent Therapy in Patients Presenting for Phase I Clinical Trials |
Q44171169 | Progressive patterns of gifitinib treating advanced non-small cell lung cancer after obtained resistance |
Q41956993 | Proliferation of Ewing sarcoma cell lines is suppressed by the receptor tyrosine kinase inhibitors gefitinib and vandetanib |
Q36838905 | Prolonged survival with erlotinib followed by afatinib in a caucasian smoker with metastatic, poorly differentiated large cell carcinoma of the lung: a case report |
Q36235591 | Promises and pitfalls in the prediction of antiepidermal growth factor receptor activity |
Q33283634 | Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers |
Q28294647 | Prompt control of bronchorrhea in patients with bronchioloalveolar carcinoma treated with gefitinib (Iressa) |
Q36095223 | Proposal for a novel methodology to screen and score cost versus survival for anticancer drugs in metastatic disease: could cost weigh in evaluation? |
Q37483993 | Prospect of JAK2 inhibitor therapy in myeloproliferative neoplasms |
Q35975657 | Prospective Evaluation of First-Line Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Carrying an Activating EGFR Mutation: A Multicenter Academic Phase II Study in Caucasian Patients (FIELT). |
Q53573913 | Prospective validation for prediction of gefitinib sensitivity by epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer. |
Q41970534 | Prospective, high-throughput molecular profiling of human gliomas |
Q37775627 | Prospects for molecular staging of non-small-cell lung cancer from genomic alterations |
Q34554617 | Prospects on strategies for therapeutically targeting oncogenic regulatory factors by small-molecule agents |
Q54518974 | Protein expression, gene amplification, and mutational analysis of EGFR in triple-negative breast cancer. |
Q35208584 | Protein kinase C-beta gene variants, pathway activation, and enzastaurin activity in lung cancer |
Q38205518 | Protein kinase inhibitors to treat non-small-cell lung cancer |
Q37417742 | Protein kinase inhibitors: contributions from structure to clinical compounds |
Q51540449 | Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas. An immunohistochemical and fluorescence in situ hybridization study. |
Q24337213 | Protein phosphorylation profiling using an in situ proximity ligation assay: phosphorylation of AURKA-elicited EGFR-Thr654 and EGFR-Ser1046 in lung cancer cells |
Q36969009 | Proteins, drug targets and the mechanisms they control: the simple truth about complex networks |
Q38461516 | Proteome research in urothelial carcinoma. |
Q35814785 | Proteomic analysis of HEK293 cells expressing non small cell lung carcinoma associated epidermal growth factor receptor variants reveals induction of heat shock response |
Q36168391 | Proteomic analysis of cellular signaling |
Q37709355 | Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor |
Q39282659 | Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. |
Q39868726 | Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer. |
Q30402667 | Proteomics and biomarkers in clinical trials for drug development |
Q33233797 | Proteomics: clinical applications for head and neck squamous cell carcinoma |
Q64269953 | Provisional Guideline Recommendation for EGFR Gene Mutation Testing in Liquid Samples of Lung Cancer Patients: A Proposal by the Korean Cardiopulmonary Pathology Study Group |
Q92951808 | Proximity proteomics identifies cancer cell membrane cis-molecular complex as a potential cancer target |
Q90383683 | Pulmonary Administration: Strengthening the Value of Therapeutic Proximity |
Q53190932 | Pulmonary adenocarcinoma with epidermal growth factor receptor-mutations in asbestos exposed non-smokers: A case series. |
Q28395348 | Pulmonary adenocarcinoma: a renewed entity in 2011 |
Q34404209 | Pulmonary adenocarcinoma: implications of the recent advances in molecular biology, treatment and the IASLC/ATS/ERS classification |
Q34284660 | Pyrosequencing data analysis software: a useful tool for EGFR, KRAS, and BRAF mutation analysis |
Q38658503 | Quality Assessment of Reporting Performance for EGFR Molecular Diagnosis in Non-Small Cell Lung Cancer |
Q36051542 | Quality of life with gefitinib in patients with EGFR-mutated non-small cell lung cancer: quality of life analysis of North East Japan Study Group 002 Trial |
Q28541305 | Quantification and kinetic analysis of Grb2-EGFR interaction on micro-patterned surfaces for the characterization of EGFR-modulating substances |
Q54979720 | Quantification and localization of oncogenic receptor tyrosine kinase variant transcripts using molecular inversion probes. |
Q37480093 | Quantification of EGFR mutations in primary and metastatic tumors in non-small cell lung cancer |
Q37190448 | Quantification of mutant alleles in circulating tumor DNA can predict survival in lung cancer. |
Q34158755 | Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array |
Q37210782 | Quantitative Secretomic Analysis Identifies Extracellular Protein Factors That Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer |
Q60307896 | Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states |
Q90292140 | Quantitative features of dual-energy spectral computed tomography for solid lung adenocarcinoma with EGFR and KRAS mutations, and ALK rearrangement: a preliminary study |
Q37330722 | Quantitative modeling perspectives on the ErbB system of cell regulatory processes |
Q37340472 | Quantitative prediction of fold resistance for inhibitors of EGFR. |
Q37649220 | Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibition |
Q98386425 | Quantitative volumetric assessment of the solid portion percentage on CT images to predict ROS1/ALK rearrangements in lung adenocarcinomas |
Q35138060 | Quantum coupled mutation finder: predicting functionally or structurally important sites in proteins using quantum Jensen-Shannon divergence and CUDA programming. |
Q42633890 | Quantum dots immunofluorescence histochemical detection of EGFR gene mutations in the non-small cell lung cancers using mutation-specific antibodies |
Q34143354 | Quinacrine overcomes resistance to erlotinib by inhibiting FACT, NF-κB, and cell-cycle progression in non-small cell lung cancer |
Q90447993 | R-spondin family members as novel biomarkers and prognostic factors in lung cancer |
Q37399367 | RAD18 polymorphisms are associated with platinum-based chemotherapy toxicity in Chinese patients with non-small cell lung cancer |
Q34138262 | RADical response puts an exceptional responder in CHKmate: a synthetic lethal curative response to DNA-damaging chemotherapy? |
Q37065818 | RECIST 1.1 in NSCLC patients with EGFR mutations treated with EGFR tyrosine kinase inhibitors: comparison with RECIST 1.0. |
Q36530631 | RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer |
Q37650677 | RET-rearranged non-small-cell lung carcinoma: a clinicopathological and molecular analysis |
Q46700376 | RETRACTED: Ca(2+)/calmodulin-dependent protein kinase IIγ, a critical mediator of the NF-κB network, is a novel therapeutic target in non-small cell lung cancer |
Q35461504 | RETRACTED: Silencing EGFR/HER3 signaling with a novel anti-EGFR domain II/IV antibody |
Q40484644 | RNA interference against a glioma-derived allele of EGFR induces blockade at G2M. |
Q33569727 | RNA interference and nonviral targeted gene therapy of experimental brain cancer |
Q35934254 | RNAi and HTS: exploring cancer by systematic loss-of-function |
Q37187716 | RNAi screen for rapid therapeutic target identification in leukemia patients |
Q33306326 | RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia |
Q41985336 | RNAi-induced synthetic lethality in cancer therapy |
Q36946705 | ROS1 copy number alterations are frequent in non-small cell lung cancer |
Q43101538 | ROS1 mutation and treatment with crizotinib in a 30-year old Caucasian woman with stage IV non-small cell lung cancer/adenocarcinoma and complete remission |
Q27851700 | ROS1 rearrangements define a unique molecular class of lung cancers |
Q39325857 | RUNX3 downregulation in human lung adenocarcinoma is independent of p53, EGFR or KRAS status. |
Q38178095 | Race and ethnicity in cancer therapy: what have we learned? |
Q40340394 | Race, gender and mutations in the prediction of anti-EGFR activity |
Q36440803 | Racial differences in oncogene mutations detected in early-stage low-grade endometrial cancers |
Q52985571 | Radiogenomic correlation in lung adenocarcinoma with epidermal growth factor receptor mutations: Imaging features and histological subtypes. |
Q40409078 | Radiogenomic evaluation of lung cancer - Are there imaging characteristics associated with lung adenocarcinomas harboring BRAF mutations? |
Q60922021 | Radiogenomics as association between non-invasive imaging features and molecular genomics of lung cancer |
Q36634305 | Radiographic assessment and therapeutic decisions at RECIST progression in EGFR-mutant NSCLC treated with EGFR tyrosine kinase inhibitors |
Q33673131 | Radiological and Clinical Features associated with Epidermal Growth Factor Receptor Mutation Status of Exon 19 and 21 in Lung Adenocarcinoma |
Q35814752 | Radiotherapy for asymptomatic brain metastasis in epidermal growth factor receptor mutant non-small cell lung cancer without prior tyrosine kinase inhibitors treatment: a retrospective clinical study |
Q38564088 | Radiotherapy of non-small-cell lung cancer in the era of EGFR gene mutations and EGF receptor tyrosine kinase inhibitors |
Q35810510 | Randomized Adjuvant Chemotherapy of EGFR-Mutated Non-Small Cell Lung Cancer Patients with or without Icotinib Consolidation Therapy |
Q50300068 | Randomized Phase II Study of Afatinib Plus Simvastatin Versus Afatinib Alone in Previously Treated Patients with Advanced Nonadenocarcinomatous Non-small Cell Lung Cancer. |
Q36951721 | Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer |
Q49928885 | Randomized phase 2 trial of pemetrexed, pemetrexed/bevacizumab, and pemetrexed/carboplatin/bevacizumab in patients with stage IIIB/IV non-small cell lung cancer and an Eastern Cooperative Oncology Group performance status of 2. |
Q37290704 | Randomized phase II clinical trial of chemo-immunotherapy in advanced nonsmall cell lung cancer |
Q37658881 | Randomized phase II study of erlotinib in combination with placebo or R1507, a monoclonal antibody to insulin-like growth factor-1 receptor, for advanced-stage non-small-cell lung cancer |
Q35817772 | Randomized phase II study of paclitaxel/carboplatin intercalated with gefitinib compared to paclitaxel/carboplatin alone for chemotherapy-naïve non-small cell lung cancer in a clinically selected population excluding patients with non-smoking adenoc |
Q37104233 | Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer. |
Q37594039 | Randomized phase II study of sequential carboplatin plus paclitaxel and gefitinib in chemotherapy-naïve patients with advanced or metastatic non-small-cell lung cancer: Long-term follow-up results |
Q33407127 | Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034. |
Q38410994 | Rapid and efficient detection of EGFR mutations in problematic cytologic specimens by high-resolution melting analysis |
Q41956182 | Rapid and simple detection of hot spot point mutations of epidermal growth factor receptor, BRAF, and NRAS in cancers using the loop-hybrid mobility shift assay |
Q33872030 | Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer |
Q39661497 | Rapid detection of the epidermal growth factor receptor mutation in non-small-cell lung cancer for analysis of acquired resistance using molecular beacons |
Q40026743 | Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). |
Q37185267 | Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3. |
Q89116419 | Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes |
Q35789960 | Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas |
Q42204869 | Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine |
Q37404105 | Rare EGFR exon 18 and exon 20 mutations in non-small-cell lung cancer on 10 117 patients: a multicentre observational study by the French ERMETIC-IFCT network |
Q90484072 | Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch |
Q47864863 | Rare and complex mutations of epidermal growth factor receptor, and efficacy of tyrosine kinase inhibitor in patients with non-small cell lung cancer |
Q38730141 | Rare cancers: a sea of opportunity |
Q90343085 | Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer |
Q38104414 | Rare mutations in non-small-cell lung cancer |
Q42506718 | Rare oncogenic mutations of predictive markers for targeted therapy in triple-negative breast cancer |
Q46466221 | Rare subtypes of adenocarcinoma of the lung |
Q37672002 | Rate of EGFR mutation testing for patients with nonsquamous non-small-cell lung cancer with implementation of reflex testing by pathologists |
Q34773458 | Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer |
Q36046225 | Rationale and clinical experience with epidermal growth factor receptor inhibitors in gynecologic malignancies |
Q92282031 | Rationale for Using Irreversible Epidermal Growth Factor Receptor Inhibitors in Combination with Phosphatidylinositol 3-Kinase Inhibitors for Advanced Head and Neck Squamous Cell Carcinoma |
Q46486238 | Rationale for combination use of targeted agents in ovarian cancer: do we have one? |
Q38514601 | Rationale for targeting the ErbB family of receptors in patients with advanced squamous cell carcinoma of the lung. |
Q36085487 | Re-biopsy by endobronchial ultrasound procedures for mutation analysis of non-small cell lung cancer after EGFR tyrosine kinase inhibitor treatment |
Q42945763 | Readministration of gefitinib in a responder after treatment discontinuation due to gefinitib-related interstitial lung disease: a case report |
Q36372611 | Real-World Data on Prognostic Factors for Overall Survival in EGFR Mutation-Positive Advanced Non-Small Cell Lung Cancer Patients Treated with First-Line Gefitinib |
Q36050294 | Real-World Patterns of EGFR Testing and Treatment with Erlotinib for Non-Small Cell Lung Cancer in the United States |
Q92326226 | Real-time PCR and targeted next-generation sequencing in the detection of low level EGFR mutations: Instructive case analyses |
Q47102256 | Real-world experience of afatinib as a first-line therapy for advanced EGFR mutation-positive lung adenocarcinoma. |
Q36729611 | Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer |
Q37458182 | Reasons for response differences seen in the V15-32, INTEREST and IPASS trials |
Q42004900 | Rebiopsy of Histological Samples in Pretreated Non-small Cell Lung Cancer: Comparison Among Rebiopsy Procedures |
Q34762839 | Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay |
Q43611330 | Rebiopsy of non-small cell lung cancer patients with acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitor: Comparison between T790M mutation-positive and mutation-negative populations. |
Q38672650 | Recent Advances in Conjugated Polymer Materials for Disease Diagnosis |
Q39079553 | Recent Development of the Second and Third Generation Irreversible Epidermal Growth Factor Receptor Inhibitors |
Q34678073 | Recent advances in personalized lung cancer medicine |
Q40143039 | Recent advances in targeted advanced lung cancer therapy in the elderly |
Q36709566 | Recent advances in targeted therapy for non-small cell lung cancer. |
Q36318531 | Recent advances in targeted therapy of human myelogenous leukaemia |
Q36491838 | Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain |
Q28070120 | Recent advances in the biology of human circulating tumour cells and metastasis |
Q88487552 | Recent advances in the management of lung cancer |
Q47105316 | Recent advances in the management of non-small cell lung cancer |
Q21092930 | Recent advances of novel targeted therapy in non-small cell lung cancer |
Q36874335 | Recent development in pharmacogenomics: from candidate genes to genome-wide association studies. |
Q36636637 | Recent developments in the chemotherapeutic options for nonsmall cell lung cancer |
Q51106997 | Recent mass spectrometry-based proteomics for biomarker discovery in lung cancer, COPD, and asthma. |
Q36492444 | Recent trends in the treatment of advanced lung cancer |
Q38023942 | Recent understanding of the molecular mechanisms for the efficacy and resistance of EGF receptor-specific tyrosine kinase inhibitors in non-small cell lung cancer. |
Q91310921 | Receptor Tyrosine Kinase Fusions as an Actionable Resistance Mechanism to EGFR TKIs in EGFR-Mutant Non-Small-Cell Lung Cancer |
Q58607138 | Receptor Tyrosine Kinase-Targeted Cancer Therapy |
Q37368256 | Receptor signaling as a regulatory mechanism of DNA repair |
Q37831148 | Receptor tyrosine kinases as therapeutic targets in rhabdomyosarcoma |
Q27851674 | Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers |
Q28082793 | Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers |
Q36738608 | Receptor tyrosine kinases: mechanisms of activation and signaling |
Q46047035 | Receptor-based predictors of response in breast cancer |
Q35102025 | Receptor-tyrosine-kinase-targeted therapies for head and neck cancer |
Q37194503 | Recurrent gene fusions in prostate cancer |
Q37118936 | Recurrent head and neck cancer: current treatment and future prospects. |
Q37262314 | Reduced Erlotinib sensitivity of epidermal growth factor receptor-mutant non-small cell lung cancer following cisplatin exposure: a cell culture model of second-line erlotinib treatment |
Q57806346 | Reducing DNA damage by formaldehyde in liquid-based cytology preservation solutions to enable the molecular testing of lung cancer specimens |
Q51587643 | Reducing experimental variability in variance-based sensitivity analysis of biochemical reaction systems. |
Q40426911 | Reduction of PTEN protein and loss of epidermal growth factor receptor gene mutation in lung cancer with natural resistance to gefitinib (IRESSA). |
Q35957585 | Reevaluation and reclassification of resected lung carcinomas originally diagnosed as squamous cell carcinoma using immunohistochemical analysis |
Q38473472 | Refining the treatment of NSCLC according to histological and molecular subtypes |
Q37645169 | Refining the treatment of advanced nonsmall cell lung cancer. |
Q28603408 | Registered report: A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations |
Q37226800 | Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. |
Q37096248 | Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains |
Q36738312 | Regulation of MAPKs by growth factors and receptor tyrosine kinases |
Q35206258 | Regulation of cell transformation by Rb-controlled redox homeostasis |
Q38074713 | Regulatory perspective on remaining challenges for utilization of pharmacogenomics-guided drug developments |
Q28391395 | Reinventing diagnostics for personalized therapy in oncology |
Q83964708 | Relapsing high grade mucoepidermoid carcinoma. Long-lasting complete response following reirradiation and EGFR blockade |
Q33634703 | Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas |
Q37183593 | Relationship between epidermal growth factor receptor gene mutation and copy number in Chinese patients with non-small cell lung cancer |
Q50989318 | Relationship between icotinib hydrochloride exposure and clinical outcome in Chinese patients with advanced non-small cell lung cancer. |
Q37058782 | Relationship between serum carcinoembryonic antigen level and epidermal growth factor receptor mutations with the influence on the prognosis of non-small-cell lung cancer patients |
Q36341825 | Relevance of epidermal growth factor receptor genomic gain in predicting clinical response to kinase inhibitors in non-small-cell lung cancer |
Q35791117 | Relevant molecular markers and targets |
Q54561641 | Reliability of the peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based test for epidermal growth factor receptor mutations integrated into the clinical practice for non-small cell lung cancers. |
Q54120286 | Reliability of using circulating tumor cells for detecting epidermal growth factor receptor mutation status in advanced non-small-cell lung cancer patients: a meta-analysis and systematic review. |
Q41767944 | Remarkable Effect of Gefitinib Retreatment in a Lung Cancer Patient With Lepidic Predominat Adenocarcinoma who had Experienced Favorable Results From Initial Treatment With Gefitinib: A Case Report |
Q36307379 | Remarkably high frequency of EGFR expression in breast carcinomas with squamous differentiation |
Q35166782 | Renal cell carcinoma and the use of sorafenib |
Q38581146 | Renal toxicity of anticancer agents targeting HER2 and EGFR. |
Q36741917 | Repeated favorable responses to epidermal growth factor receptor-tyrosine kinase inhibitors in a case of advanced lung adenocarcinoma |
Q24658420 | Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses |
Q35063579 | Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients |
Q34185518 | Reproductive factors, hormone use, and risk for lung cancer in postmenopausal women, the Nurses' Health Study |
Q58792355 | Requirement for MUC5AC in KRAS-dependent lung carcinogenesis |
Q36330264 | Research progress on criteria for discontinuation of EGFR inhibitor therapy |
Q36113804 | Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer |
Q27853298 | Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F. |
Q53718494 | Resistance is futile: overcoming resistance to targeted therapies in lung adenocarcinoma. |
Q37487158 | Resistance mechanisms of tumour cells to EGFR inhibitors |
Q47715159 | Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer |
Q42557873 | Resistance to EGFR-TKI can be mediated through multiple signaling pathways converging upon cap-dependent translation in EGFR-wild type NSCLC. |
Q51004850 | Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling. |
Q34392733 | Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer |
Q38930367 | Resistance to Therapy |
Q38626744 | Resistance to cancer treatment: the role of somatic genetic events and the challenges for targeted therapies |
Q55191884 | Resistance to epidermal growth factor receptor tyrosine kinase inhibitors, T790M, and clinical trials. |
Q79443198 | Resistance to gefitinib |
Q37715457 | Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathway |
Q26739760 | Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy? |
Q41634338 | Resistances to targeted therapies and strategy for following therapeutic lines in metastatic NSCLC |
Q38012422 | Respiratory cytology in the era of molecular diagnostics: a review |
Q38931077 | Response to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma with the Rare Epidermal Growth Factor Receptor Mutation S768I: a Retrospective Analysis and Literature Review |
Q46941491 | Response to dual blockade of epidermal growth factor receptor (EGFR) and cycloxygenase-2 in nonsmall cell lung cancer may be dependent on the EGFR mutational status of the tumor |
Q33576476 | Response to erlotinib in recurrent glioblastoma multiforme showing coexpression of EGFRvIII and PTEN. |
Q36225230 | Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha |
Q28306934 | Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation |
Q29618727 | Restoration of p53 function leads to tumour regression in vivo |
Q44843905 | Restriction endonuclease-mediated real-time digestion-PCR for somatic mutation detection |
Q58417919 | Results of the UK NEQAS for Molecular Genetics reference sample analysis |
Q33881153 | Retinoic Acid affects Lung Adenocarcinoma growth by inducing differentiation via GATA6 activation and EGFR and Wnt inhibition |
Q84723308 | Retrospective subset analyses in early breast cancer revisited |
Q24611142 | Retroviral oncogenes: a historical primer |
Q54794454 | Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications. |
Q36041152 | Review article: the potential of combinational regimen with non-steroidal anti-inflammatory drugs in the chemoprevention of colorectal cancer |
Q34180683 | Review of EGFR TKIs in Metastatic NSCLC, Including Ongoing Trials |
Q37290444 | Review of erlotinib in the treatment of advanced non-small cell lung cancer. |
Q27015079 | Review of the current targeted therapies for non-small-cell lung cancer |
Q34449725 | Review of the regulations for clinical research in herbal medicines in USA. |
Q36461805 | Review of the treatment of non-small cell lung cancer with gefitinib |
Q37093554 | Revisiting clinical trials using EGFR inhibitor-based regimens in patients with advanced non-small cell lung cancer: a retrospective analysis of an MD Anderson Cancer Center phase I population |
Q35668629 | Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas. |
Q36015618 | Rhizoma Paridis Saponins Induces Cell Cycle Arrest and Apoptosis in Non-Small Cell Lung Carcinoma A549 Cells |
Q36413425 | Rhodomycin A, a novel Src-targeted compound, can suppress lung cancer cell progression via modulating Src-related pathways |
Q57918768 | Risk factors differ for non-small-cell lung cancers with and without EGFR mutation: assessment of smoking and sex by a case-control study in Japanese |
Q37697247 | Risk factors of brain metastasis during the course of EGFR-TKIs therapy for patients with EGFR-mutated advanced lung adenocarcinoma |
Q35584486 | Role of 18F-fluorodeoxyglucose positron emission tomography in predicting epidermal growth factor receptor mutations in non-small cell lung cancer |
Q38818845 | Role of Cytochrome P450 3A4 and 1A2 Phenotyping in Patients with Advanced Non-small-Cell Lung Cancer Receiving Erlotinib Treatment. |
Q38486882 | Role of EGFR mutations in lung cancers: prognosis and tumor chemosensitivity. |
Q54980093 | Role of Epidermal Growth Factor Receptor (EGFR) Inhibitors and Radiation in the Management of Brain Metastases from EGFR Mutant Lung Cancers. |
Q37153625 | Role of ErbB4 in breast cancer |
Q38087392 | Role of FGF receptors as an emerging therapeutic target in lung squamous cell carcinoma. |
Q26781683 | Role of HER2 in NSCLC |
Q53711253 | Role of HGF-MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer. |
Q35067488 | Role of IGF-binding protein 3 in the resistance of EGFR mutant lung cancer cells to EGFR-tyrosine kinase inhibitors |
Q54340378 | Role of [¹⁸F]FDG PET in prediction of KRAS and EGFR mutation status in patients with advanced non-small-cell lung cancer. |
Q36622102 | Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. |
Q37320346 | Role of epidermal growth factor receptor in breast cancer |
Q36155957 | Role of epidermal growth factor receptor mutations in predicting sensitivity or resistance to targeted agents in non-small-cell lung cancer |
Q36475391 | Role of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of esophageal carcinoma and the suggested mechanisms of action |
Q34417886 | Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer |
Q35919264 | Role of erlotinib in the management of pancreatic cancer. |
Q37591935 | Role of erlotinib in the targeted treatment of non-small-cell lung cancer in Chinese patients |
Q26866485 | Role of erlotinib in the treatment of non-small cell lung cancer: clinical outcomes in wild-type epidermal growth factor receptor patients |
Q26750428 | Role of gefitinib in the targeted treatment of non-small-cell lung cancer in Chinese patients |
Q37956397 | Role of genotyping in non-small cell lung cancer treatment: current status |
Q92134595 | Role of liquid biopsy in oncogene-addicted non-small cell lung cancer |
Q27027957 | Role of mesenchymal-epithelial transition amplification in resistance to anti-epidermal growth factor receptor agents |
Q36950439 | Role of miRNA in carcinogenesis and biomarker selection: a methodological view |
Q33576845 | Role of network branching in eliciting differential short-term signaling responses in the hypersensitive epidermal growth factor receptor mutants implicated in lung cancer |
Q36616926 | Role of novel targeted therapies in the clinic |
Q50050619 | Role of particle beam therapy in a trimodality approach to locally advanced non-small cell lung cancer. |
Q37288681 | Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation Consortium |
Q28242840 | Role of receptor tyrosine kinases in gastric cancer: new targets for a selective therapy |
Q34705858 | Roles for growth factors in cancer progression |
Q35111284 | Roles of EGFR and KRAS Mutations in the Treatment Of Patients With Non-Small-Cell Lung Cancer |
Q36477469 | Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes. |
Q37627937 | Roles of pathologists in molecular targeted cancer therapy |
Q41605055 | Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer-ready for prime-time? |
Q33599057 | Routine genetic testing of lung cancer specimens derived from surgery, bronchoscopy and fluid aspiration by next generation sequencing |
Q40096915 | Routine molecular profiling of patients with advanced non-small-cell lung cancer: results of a 1-year nationwide programme of the French Cooperative Thoracic Intergroup (IFCT). |
Q36695771 | S100A2 is strongly expressed in airway basal cells, preneoplastic bronchial lesions and primary non-small cell lung carcinomas |
Q100512512 | S6K1 blockade overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer |
Q84706708 | SEOM clinical guidelines for using molecular markers in clinical practice |
Q38833666 | SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer |
Q37246242 | SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers |
Q28818608 | SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers |
Q41876194 | SMC1A knockdown induces growth suppression of human lung adenocarcinoma cells through G1/S cell cycle phase arrest and apoptosis pathways in vitro |
Q34989327 | SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women |
Q41642309 | SPARC is a possible predictive marker for albumin-bound paclitaxel in non-small-cell lung cancer |
Q37662776 | SR48692 inhibits non-small cell lung cancer proliferation in an EGF receptor-dependent manner |
Q35570442 | SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines |
Q30821792 | STAC: A method for testing the significance of DNA copy number aberrations across multiple array-CGH experiments |
Q47412228 | Safety and discomfort during bronchoscopy performed under sedation with fentanyl and midazolam: a prospective study |
Q44555068 | Safety and effectiveness of stereotactic body radiotherapy for a clinically diagnosed primary stage I lung cancer without pathological confirmation |
Q46764329 | Safety and efficacy of sequential chemotherapy with carboplatin plus gemcitabine followed by weekly paclitaxel in advanced non-small cell lung cancer |
Q43965995 | Safety and pharmacokinetics of high-dose gefitinib in patients with solid tumors: results of a phase I study. |
Q38841473 | Safety of gefitinib in non-small cell lung cancer treatment |
Q38786021 | Safety profiles of first-line therapies for metastatic non-squamous non-small-cell lung cancer |
Q37364638 | Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study. |
Q58704176 | Score for lung adenocarcinoma in China with EGFR mutation of exon 19: Combination of clinical and radiological characteristics analysis |
Q34497010 | Screening for EGFR Mutations in Patients with Head and Neck Cancer Treated with Gefitinib on a Compassionate-Use Program: A Hellenic Cooperative Oncology Group Study |
Q34032012 | Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR. |
Q40251351 | Screens using RNAi and cDNA expression as surrogates for genetics in mammalian tissue culture cells |
Q30488528 | SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical-protein interactome |
Q37177594 | Searching for a magic bullet in NSCLC: the role of epidermal growth factor receptor mutations and tyrosine kinase inhibitors |
Q93185180 | Second-generation EGFR and ErbB tyrosine kinase inhibitors as first-line treatments for non-small cell lung cancer |
Q36904574 | Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in lung cancers |
Q36268315 | Second-generation kinase inhibitors |
Q38155201 | Second-line systemic therapy for metastatic urothelial carcinoma of the bladder |
Q47861831 | Second-line therapy of squamous non-small cell lung cancer: an evolving landscape |
Q80100973 | Second-line treatment of non-small cell lung cancer: big targets, small progress; small targets, big progress? |
Q37945643 | Second-line treatment of non-small-cell lung cancer: chemotherapy or tyrosine kinase inhibitors? |
Q53854603 | Selected highlights from the 5th International Conference on Ovarian Cancer. Houston, TX, USA, 1-4 December 2004. |
Q90468769 | Selecting short length nucleic acids localized in exosomes improves plasma EGFR mutation detection in NSCLC patients |
Q44915706 | Selecting the right patient for tumor therapy |
Q37730020 | Selection criteria for c-Met-targeted therapies: emerging evidence for biomarkers |
Q41678123 | Selection of Non-small Cell Lung Cancer Patients for Intercalated Chemotherapy and Tyrosine Kinase Inhibitors |
Q34384968 | Selection of extreme phenotypes: the role of clinical observation in translational research. |
Q58151801 | Selective Energy Transfer Between Quantum Dots and Gold Nanoparticles for Detection of Multiple Mutations in Epidermal Growth Factor Receptor |
Q34354339 | Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells |
Q47226790 | Selective heat generation in cancer cells using a combination of 808 nm laser irradiation and the folate-conjugated Fe2O3@Au nanocomplex. |
Q36616873 | Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib |
Q40862682 | Selectivity profile of afatinib for EGFR-mutated non-small-cell lung cancer. |
Q61456218 | Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells |
Q51293195 | Semiautomated laser capture microdissection of lung adenocarcinoma cytology samples. |
Q36746316 | Sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells |
Q79787202 | Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing |
Q35189160 | Sensitivity analysis of biological Boolean networks using information fusion based on nonadditive set functions |
Q37468539 | Sensitivity and resistance to EGF-R inhibitors: approaches to enhance the efficacy of EGF-R antibodies |
Q36611196 | Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition |
Q33510934 | Sequence and structure signatures of cancer mutation hotspots in protein kinases |
Q34201724 | Sequence-dependent effect of docetaxel with gefitinib on the proliferation and apoptosis of lung adenocarcinoma cell H1975 |
Q91704405 | Sequential analysis of transcript expression patterns improves survival prediction in multiple cancers |
Q37378176 | Sequential molecular changes during multistage pathogenesis of small peripheral adenocarcinomas of the lung |
Q33995172 | Sequential treatment of icotinib after first-line pemetrexed in advanced lung adenocarcinoma with unknown EGFR gene status |
Q34614608 | Serum APE1 autoantibodies: a novel potential tumor marker and predictor of chemotherapeutic efficacy in non-small cell lung cancer |
Q36695530 | Serum EGF-receptor and HER-2 extracellular domains and prognosis of non-small-cell lung cancer |
Q90409971 | Serum Platelet-Derived Growth Factor Is Significantly Lower in Patients with Lung Cancer and Continued to Decrease After Platinum-Based Chemotherapy |
Q55011252 | Serum VEGF levels in the early diagnosis and severity assessment of non-small cell lung cancer. |
Q46946875 | Serum carcinoembryonic antigen level is associated with epidermal growth factor receptor mutations in recurrent lung adenocarcinomas |
Q54680146 | Serum levels of surfactant protein D predict the anti-tumor activity of gefitinib in patients with advanced non-small cell lung cancer. |
Q54977786 | Serum peptide expression and treatment responses in patients with advanced non-small-cell lung cancer. |
Q35034044 | Serum proteomic study on EGFR-TKIs target treatment for patients with NSCLC. |
Q36839768 | Setting the benchmark for tailoring treatment with EGFR tyrosine kinase inhibitors |
Q40201980 | Setup and characterization of a human head and neck squamous cell carcinoma xenograft model in nude rats |
Q37401172 | Sex-specific aspects of tumor therapy |
Q39194466 | Shedding of c-Met ectodomain correlates with c-Met expression in non-small cell lung cancer |
Q41701853 | Shikonin enhances Adriamycin antitumor effects by inhibiting efflux pumps in A549 cells |
Q58759414 | Short-Term Responders of Non-Small Cell Lung Cancer Patients to EGFR Tyrosine Kinase Inhibitors Display High Prevalence of TP53 Mutations and Primary Resistance Mechanisms |
Q37411082 | Should primary tumor be resected for non-small cell lung cancer with malignant pleural disease unexpectedly found during operation?-a systemic review and meta-analysis |
Q37847104 | Signal transduction inhibitors and antiangiogenic therapies for malignant glioma |
Q27027778 | Signaling cross-talk in the resistance to HER family receptor targeted therapy |
Q35987785 | Signaling multiplex of the epidermal growth factor receptor |
Q36392991 | Signaling networks assembled by oncogenic EGFR and c-Met |
Q34072567 | Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo |
Q38805800 | Signatures of drug sensitivity in nonsmall cell lung cancer |
Q64250706 | Significance of EGFR and PTEN Expression and PLR and NLR for Predicting the Prognosis of Epithelioid Malignant Peritoneal Mesothelioma |
Q34886787 | Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non-small cell lung cancer treated with radiotherapy for brain metastases |
Q34427354 | Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice |
Q37034341 | Significant increase in hEGF uptake is correlated with formation of EGFR dimers induced by the EGFR tyrosine kinase inhibitor gefitinib |
Q89497005 | Silence of S1 RNA binding domain 1 represses cell growth and promotes apoptosis in human non-small cell lung cancer cells |
Q28547292 | Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma |
Q36216766 | Simultaneous detection of expression and gene mutations of HER2/neu in Chinese patients with gastric cancer |
Q43860596 | Simultaneous diagnostic platform of genotyping EGFR, KRAS, and ALK in 510 Korean patients with non-small-cell lung cancer highlights significantly higher ALK rearrangement rate in advanced stage |
Q36782324 | Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy |
Q34589774 | Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model. |
Q40472879 | Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with speci |
Q52583236 | Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations. |
Q34523257 | Single-Tube Mutation Scanning of The Epidermal Growth Factor Receptor Gene Using Multiplex LATE-PCR and Lights-On/Lights-Off Probes |
Q83015772 | Single-arm phase II study of multiagent concurrent chemoradiotherapy and gefitinib in locoregionally advanced squamous cell carcinoma of the head and neck |
Q91721637 | Single-molecule functional anatomy of endogenous HER2-HER3 heterodimers |
Q28069454 | Skin problems and EGFR-tyrosine kinase inhibitor |
Q39637704 | Slug confers resistance to the epidermal growth factor receptor tyrosine kinase inhibitor |
Q48070194 | Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation |
Q27027835 | Small molecule compounds targeting the p53 pathway: are we finally making progress? |
Q38219688 | Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer |
Q37238413 | Smoking status and self-reported race affect the frequency of clinically relevant oncogenic alterations in non-small-cell lung cancers at a United States-based academic medical practice. |
Q46971338 | Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma |
Q35602124 | Soluble epidermal growth factor receptor (sEGFR) and carcinoembryonic antigen (CEA) concentration in patients with non-small cell lung cancer: correlation with survival after erlotinib and gefitinib treatment |
Q37502708 | Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC. |
Q36200850 | Somatic Mutation Spectrum of Non-Small-Cell Lung Cancer in African Americans: A Pooled Analysis. |
Q37294797 | Somatic microindels in human cancer: the insertions are highly error-prone and derive from nearby but not adjacent sense and antisense templates |
Q99607554 | Somatic mutation detection efficiency in EGFR: a comparison between high resolution melting analysis and Sanger sequencing |
Q36014517 | Somatic mutation in synchronous primary adenocarcinomas of the left lung: a case report |
Q46880458 | Somatic mutation of PHF6 gene in T-cell acute lymphoblatic leukemia, acute myelogenous leukemia and hepatocellular carcinoma |
Q24648102 | Somatic mutations affect key pathways in lung adenocarcinoma |
Q42706743 | Somatic mutations and immunotherapy outcome with CTLA-4 blockade in melanoma |
Q52590998 | Somatic mutations of ErbB4: selective loss-of-function phenotype affecting signal transduction pathways in cancer. |
Q38512879 | Somatic mutations of the ERBB4 kinase domain in human cancers |
Q24648133 | Somatic mutations of the epidermal growth factor receptor and non-small-cell lung cancer |
Q37235024 | Somatic pharmacogenomics in cancer |
Q35749438 | Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas |
Q36028660 | Some lessons learned from imatinib mesylate clinical development in gastrointestinal stromal tumors |
Q33582914 | Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways |
Q38020917 | Sorafenib in non-small cell lung cancer |
Q36708741 | Sorafenib: where do we go from here? |
Q39202557 | Sorting nexin 2-mediated membrane trafficking of c-Met contributes to sensitivity of molecular-targeted drugs |
Q33405933 | Southwestern oncology group phase II trial (S0526) of pemetrexed in bronchioloalveolar carcinoma subtypes of advanced adenocarcinoma |
Q39714753 | Spatial and temporal genetic heterogeneity of epidermal growth factor receptor gene status in a patient with non-small cell lung cancer: a case report |
Q37995451 | Specific biomarkers of receptors, pathways of inhibition and targeted therapies: pre-clinical developments. |
Q40127625 | Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value |
Q40669345 | Specific killing of Rb mutant cancer cells by inactivating TSC2. |
Q89750470 | Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan-cancer analysis |
Q35036895 | Spectrum of EGFR gene copy number changes and KRAS gene mutation status in Korean triple negative breast cancer patients |
Q36815913 | Spectrum of EGFR gene mutations and ALK rearrangements in lung cancer patients in Turkey |
Q47930093 | Spectrum of EGFR gene mutations in Vietnamese patients with non-small cell lung cancer |
Q33563803 | Spectrum of LKB1, EGFR, and KRAS mutations in chinese lung adenocarcinomas |
Q30837003 | SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples |
Q37137372 | Sputum-based molecular biomarkers for the early detection of lung cancer: limitations and promise |
Q30278774 | Src inhibitors act through different mechanisms in Non-Small Cell Lung Cancer models depending on EGFR and RAS mutational status |
Q39033091 | Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer |
Q35207876 | Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells |
Q47390697 | Standard-dose osimertinib for refractory leptomeningeal metastases in T790M-positive EGFR-mutant non-small cell lung cancer |
Q35167923 | Standardization of epidermal growth factor receptor (EGFR) measurement by quantitative immunofluorescence and impact on antibody-based mutation detection in non-small cell lung cancer |
Q52673091 | Standardizing biomarker testing for Canadian patients with advanced lung cancer. |
Q36271949 | State of the art in therapy for non-small cell lung cancer |
Q34681069 | State of the art: Response assessment in lung cancer in the era of genomic medicine |
Q34089332 | State-of-the-art MS technology applications in lung disease. |
Q36269651 | Statin improves survival in patients with EGFR-TKI lung cancer: A nationwide population-based study |
Q36117881 | Strategic plans to promote head and neck cancer translational research within the radiation therapy oncology group: a report from the translational research program |
Q84623471 | Strategies for overcoming EGFR resistance in the treatment of advanced-stage NSCLC |
Q37856721 | Strategies to improve radiotherapy with targeted drugs |
Q38838227 | Strategies to overcome acquired resistances conferred by mutations in the kinase domain of EGFR. |
Q35968384 | Strategies to overcome resistance to targeted protein kinase inhibitors |
Q35017477 | Stratification of non-small cell lung cancer patients for therapy with epidermal growth factor receptor inhibitors: the EGFR fluorescence in situ hybridization assay |
Q54957856 | Stressing the need to overcome EGFR tyrosine kinase inhibitor resistance. |
Q42119491 | Structural Differences between Wild-Type and Double Mutant EGFR Modulated by Third-Generation Kinase Inhibitors |
Q33810641 | Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer |
Q27677383 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor |
Q41593246 | Structural basis of mutant-selectivity and drug-resistance related to CO-1686. |
Q90179057 | Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation |
Q52345422 | Structural insights into drug development strategy targeting EGFR T790M/C797S. |
Q35652106 | Structural investigations of T854A mutation in EGFR and identification of novel inhibitors using structure activity relationships |
Q42768815 | Structural signature of the G719S-T790M double mutation in the EGFR kinase domain and its response to inhibitors. |
Q36181814 | Structural systems biology and multiscale signaling models |
Q92658888 | Structural variation and its potential impact on genome instability: Novel discoveries in the EGFR landscape by long-read sequencing |
Q27680966 | Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer |
Q92934599 | Structure and Dynamics of the EGF Receptor as Revealed by Experiments and Simulations and Its Relevance to Non-Small Cell Lung Cancer |
Q37122918 | Structure and clinical relevance of the epidermal growth factor receptor in human cancer |
Q33680363 | Structure and function of epigen, the last EGFR ligand |
Q33812445 | Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors. |
Q49344251 | Structure-based pharmacophore design and virtual screening for novel potential inhibitors of epidermal growth factor receptor as an approach to breast cancer chemotherapy. |
Q38987589 | Structure-functional prediction and analysis of cancer mutation effects in protein kinases. |
Q27643967 | Structure-guided development of affinity probes for tyrosine kinases using chemical genetics |
Q27644014 | Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity |
Q40694780 | Study of Gefitinib and Pemetrexed as First-Line Treatment in Patients with Advanced Non-Small Cell Lung Cancer Harboring EGFR Mutation |
Q37389611 | Study of efficacy and safety of pulsatile administration of high-dose gefitinib or erlotinib for advanced non-small cell lung cancer patients with secondary drug resistance: A single center, single arm, phase II clinical trial |
Q35700405 | Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer |
Q35929525 | Studying a complex tumor: potential and pitfalls |
Q35596310 | Studying clonal dynamics in response to cancer therapy using high-complexity barcoding. |
Q37127423 | Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy |
Q89995873 | Subtyping and EGFR mutation testing from blocks of cytological materials, based on liquid-based cytology for lung cancer at bronchoscopic examinations |
Q44574005 | Subtyping of pulmonary adenocarcinoma in cytologic specimens: the next challenge |
Q36324363 | Successes and failures of the teachable moment: smoking cessation in cancer patients |
Q38721743 | Sufficiency of Single-Arm Studies to Support Registration of Targeted Agents in Molecularly Selected Patients with Cancer: Lessons from the Clinical Development of Crizotinib |
Q44126874 | Sunitinib in pretreated advanced non-small-cell lung carcinoma: a primary result from Asian population |
Q38721555 | Superior Efficacy and Selectivity of Novel Small-Molecule Kinase Inhibitors of T790M-Mutant EGFR in Preclinical Models of Lung Cancer |
Q61798869 | Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity |
Q28477887 | Suppression of expression of heat shock protein 70 by gefitinib and its contribution to pulmonary fibrosis |
Q37179584 | Surgical treatment for primary pulmonary lymphoepithelioma-like carcinoma |
Q36439350 | Surgical treatment for pulmonary pleomorphic carcinoma: A retrospective study of 60 patients |
Q47417911 | Surrogate end points for survival in the target treatment of advanced non-small-cell lung cancer with gefitinib or erlotinib |
Q40315977 | Survival Gains from First-Line Systemic Therapy in Metastatic Non-Small Cell Lung Cancer in the U.S., 1990-2015: Progress and Opportunities |
Q54977347 | Survival analysis and pathological features of advanced non-small cell lung cancer with miliary pulmonary metastases in patients harboring epidermal growth factor receptor mutations. |
Q30574736 | Survival and death signals can predict tumor response to therapy after oncogene inactivation |
Q36311791 | Survival impact of epidermal growth factor receptor overexpression in patients with non-small cell lung cancer: a meta-analysis |
Q51785555 | Survival outcome and predictors of gefitinib antitumor activity in East Asian chemonaive patients with advanced nonsmall cell lung cancer. |
Q37761935 | Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics |
Q49873962 | Survival-associated factors of first-line EGFR-tyrosine kinase inhibitor responders and non-responders in lung adenocarcinoma patients with common EGFR mutations. |
Q54375452 | Survivin mRNA expression in blood as a predictor of the response to EGFR-tyrosine kinase inhibitors and prognosis in patients with non-small cell lung cancer. |
Q45041454 | Switching on kinases: oncogenic activation of BRAF and the PDGFR family |
Q41969702 | Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer |
Q33837881 | Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy |
Q49387613 | Synergistic effect of targeting dishevelled-3 and the epidermal growth factor receptor-tyrosine kinase inhibitor on mesothelioma cells in vitro. |
Q39388106 | Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway |
Q40409431 | Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma |
Q39429719 | Synergistic inhibitory effects by the combination of gefitinib and genistein on NSCLC with acquired drug-resistance in vitro and in vivo |
Q39499521 | Synergistic interaction between sunitinib and docetaxel is sequence dependent in human non-small lung cancer with EGFR TKIs-resistant mutation |
Q39280914 | Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma |
Q44851135 | Synthesis and anticancer activity of new quinazoline derivatives |
Q33847057 | Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents |
Q28820988 | Synthesis and biological evaluation of matrine derivatives containing benzo-α-pyrone structure as potent anti-lung cancer agents |
Q39413333 | Synthetic essentiality: Targeting tumor suppressor deficiencies in cancer |
Q38801969 | Systematic Computational Identification of Variants That Activate Exonic and Intronic Cryptic Splice Sites |
Q36539506 | Systematic Prioritization of Druggable Mutations in ∼5000 Genomes Across 16 Cancer Types Using a Structural Genomics-based Approach |
Q35854835 | Systematic analysis of genetic alterations in tumors using Cancer Genome WorkBench (CGWB). |
Q89900731 | Systematic comparison of somatic variant calling performance among different sequencing depth and mutation frequency |
Q33826328 | Systematic comparison of two whole-genome amplification methods for targeted next-generation sequencing using frozen and FFPE normal and cancer tissues |
Q29547695 | Systematic identification of genomic markers of drug sensitivity in cancer cells |
Q37331472 | Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer |
Q58774943 | Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma |
Q34865629 | Systemic Nocardiosis Mimicking Disease Flare-up after Discontinuation of Gefitinib in a Patient with EGFR-Mutant Lung Cancer |
Q54978262 | Systemic Therapy of Lung Cancer CNS Metastases Using Molecularly Targeted Agents and Immune Checkpoint Inhibitors. |
Q38285931 | Systemic therapy of brain metastases. |
Q47585577 | Systems Biology: a new hope for drug discovery? |
Q90324481 | Systems Modeling Identifies Divergent Receptor Tyrosine Kinase Reprogramming to MAPK Pathway Inhibition |
Q38066235 | Systems biology technologies enable personalized traditional Chinese medicine: a systematic review |
Q54627325 | Systems biology-embedded target validation: improving efficacy in drug discovery. |
Q58765906 | T790M Correlates with Longer Progression-free Survival in Non-small Cell Lung Carcinomas Harboring Mutations |
Q40012030 | TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer |
Q34345632 | TAGCNA: a method to identify significant consensus events of copy number alterations in cancer |
Q35525917 | TAK-701, a humanized monoclonal antibody to hepatocyte growth factor, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation |
Q42286893 | TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling |
Q28393844 | TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer |
Q34100276 | TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer |
Q45286133 | TGFalpha expression impairs Trastuzumab-induced HER2 downregulation |
Q36285249 | TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice |
Q41959361 | TKIs in NSCLC: the down of a new era? |
Q38853578 | TLG-S criteria are superior to both EORTC and PERCIST for predicting outcomes in patients with metastatic lung adenocarcinoma treated with erlotinib |
Q52317261 | TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer. |
Q42259718 | TRAIL apoptotic pathway-targeted therapies for NSCLC. |
Q39373269 | TRPC1 protein channel is major regulator of epidermal growth factor receptor signaling |
Q34137429 | TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma |
Q36836799 | TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia |
Q36956724 | Tackling EGFR signaling with TACE antagonists: a rational target for metalloprotease inhibitors in cancer |
Q36430761 | Tailor-made chemotherapy for non-small cell lung cancer patients |
Q35927501 | Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors |
Q37851009 | Taming the dragon: genomic biomarkers to individualize the treatment of cancer. |
Q38669277 | Target Therapy in Lung Cancer |
Q34898454 | Target therapies in lung cancer |
Q42582783 | Target therapy in NSCLC patients: Relevant clinical agents and tumour molecular characterisation |
Q42328292 | Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer |
Q90672582 | Targeted Molecular Treatments in Non-Small Cell Lung Cancer: A Clinical Guide for Oncologists |
Q38930362 | Targeted Therapies for Lung Cancer |
Q34030379 | Targeted Therapies in Lung Cancer |
Q28083446 | Targeted Therapies in Non-Small Cell Lung Cancer-Beyond EGFR and ALK |
Q39192200 | Targeted Treatment of Brain Metastases |
Q38100162 | Targeted agents in non-small cell lung cancer therapy: What is there on the horizon? |
Q36616922 | Targeted antitumour therapy--future perspectives |
Q36920799 | Targeted cancer therapies based on antibodies directed against epidermal growth factor receptor: status and perspectives |
Q36786085 | Targeted cancer therapy: promise and reality |
Q34356166 | Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer |
Q38956321 | Targeted inhibition in tumors with ALK dependency |
Q34683348 | Targeted inhibition of kinases in cancer therapy |
Q44992034 | Targeted lung cancer therapies |
Q26862516 | Targeted molecular therapies against epidermal growth factor receptor: past experiences and challenges |
Q37807159 | Targeted molecular therapy in melanoma |
Q36113026 | Targeted molecular therapy of malignant gliomas |
Q82494790 | Targeted molecular therapy of malignant gliomas |
Q37392703 | Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium). |
Q36128449 | Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA |
Q26738986 | Targeted therapies and immunotherapy in non-small-cell lung cancer |
Q35589492 | Targeted therapies for advanced Ewing sarcoma family of tumors |
Q35919642 | Targeted therapies for cancer 2004. |
Q36046241 | Targeted therapies for gynecologic malignancies |
Q54411624 | Targeted therapies for locally advanced or metastatic squamous cell carcinoma of the lung. |
Q36054970 | Targeted therapies for lung cancer: clinical experience and novel agents |
Q42431459 | Targeted therapies for lung cancer: how did the game begin? |
Q36150842 | Targeted therapies for prostate cancer |
Q49961144 | Targeted therapies for targeted populations: Anti-EGFR treatment for EGFR amplified gastroesophageal adenocarcinoma. |
Q38625550 | Targeted therapies for treatment of non-small cell lung cancer--Recent advances and future perspectives |
Q36934791 | Targeted therapies in bladder cancer--an update |
Q36051459 | Targeted therapies in breast cancer. |
Q27022852 | Targeted therapies in development for non-small cell lung cancer |
Q33606699 | Targeted therapies in epithelial ovarian cancer |
Q34878868 | Targeted therapies in epithelial ovarian cancer: Molecular mechanisms of action |
Q36990546 | Targeted therapies in non-small cell lung cancer |
Q42845478 | Targeted therapies: Tyrosine-kinase inhibitors--new standard for NSCLC therapy |
Q37956110 | Targeted therapies: how personal should we go? |
Q33807742 | Targeted therapy for cancer: the gastrointestinal stromal tumor model |
Q38390200 | Targeted therapy for non-small cell lung cancer: current standards and the promise of the future |
Q37096910 | Targeted therapy for squamous cell lung cancer |
Q37204270 | Targeted therapy in cancer |
Q35207561 | Targeted therapy in hepatocellular carcinoma |
Q37246286 | Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer |
Q38042324 | Targeted therapy in rare cancers--adopting the orphans |
Q37290520 | Targeted therapy of advanced non-small cell lung cancer: the role of bevacizumab |
Q49956245 | Targeted therapy of brain metastases: latest evidence and clinical implications. |
Q37897792 | Targeted therapy of non-small-cell lung carcinoma. |
Q36026004 | Targeted therapy: a new approach for the treatment of locally advanced oropharyngeal cancer. |
Q37781113 | Targeted therapy: an evolving world of lung cancer. |
Q35671213 | Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer |
Q36933081 | Targeting ALK in neuroblastoma--preclinical and clinical advancements |
Q38673845 | Targeting ALK-rearranged non-small-cell lung cancer: an update |
Q90133295 | Targeting Autophagy for Overcoming Resistance to Anti-EGFR Treatments |
Q27658951 | Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors |
Q33889144 | Targeting CCR2 with its antagonist suppresses viability, motility and invasion by downregulating MMP-9 expression in non-small cell lung cancer cells |
Q40095585 | Targeting EGFR in bladder cancer |
Q37258827 | Targeting EGFR in lung cancer: Lessons learned and future perspectives |
Q37405633 | Targeting EGFR resistance networks in head and neck cancer. |
Q27027433 | Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities |
Q33750719 | Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas |
Q27002155 | Targeting EML4-ALK driven non-small cell lung cancer (NSCLC) |
Q92035698 | Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer |
Q34174883 | Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? |
Q53688274 | Targeting General Transcriptional Machinery as a Therapeutic Strategy for Adult T-Cell Leukemia. |
Q36898642 | Targeting HER proteins in cancer therapy and the role of the non-target HER3. |
Q36429516 | Targeting HER1/EGFR in cancer therapy: experience with erlotinib |
Q35890128 | Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum |
Q37603214 | Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells |
Q42606238 | Targeting IGF-1R: throwing out the baby with the bathwater? |
Q36398758 | Targeting KRAS-mutant non-small cell lung cancer: challenges and opportunities. |
Q37539304 | Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitors |
Q42369856 | Targeting Novel but Less Common Driver Mutations and Chromosomal Translocations in Advanced Non-Small Cell Lung Cancer |
Q29617685 | Targeting PI3K signalling in cancer: opportunities, challenges and limitations |
Q33554884 | Targeting PTPs with small molecule inhibitors in cancer treatment |
Q37293656 | Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma |
Q38608540 | Targeting Signaling Transduction Pathways in Bladder Cancer |
Q35575242 | Targeting TACE-dependent EGFR ligand shedding in breast cancer |
Q36580144 | Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation |
Q92693295 | Targeting an EGFR Water Network with 4-Anilinoquin(az)oline Inhibitors for Chordoma |
Q37435616 | Targeting aromatase and estrogen signaling in human non-small cell lung cancer |
Q38767073 | Targeting asparagine and autophagy for pulmonary adenocarcinoma therapy |
Q37800284 | Targeting cytoskeleton reorganisation as antimetastatic treatment. |
Q36983136 | Targeting epidermal growth factor receptor and SRC pathways in head and neck cancer |
Q36656097 | Targeting epidermal growth factor receptor for head and neck squamous cell carcinoma: still lost in translation? |
Q37768460 | Targeting epidermal growth factor receptor in the treatment of non-small-cell lung cancer |
Q36613969 | Targeting epidermal growth factor receptor signaling in the treatment of head and neck cancer |
Q37789955 | Targeting erbB receptors |
Q64118764 | Targeting exon 20 insertion mutations in non-small cell lung cancer |
Q53078264 | Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor. |
Q89533973 | Targeting gallbladder cancer: a pathway based perspective |
Q37068767 | Targeting genomic alterations in squamous cell lung cancer |
Q90481579 | Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors |
Q37849013 | Targeting mutant fibroblast growth factor receptors in cancer |
Q34627751 | Targeting of Both the c-Met and EGFR Pathways Results in Additive Inhibition of Lung Tumorigenesis in Transgenic Mice |
Q39007950 | Targeting of EGF-displayed protein nanoparticles with anticancer drugs. |
Q38388217 | Targeting of MEK in lung cancer therapeutics |
Q35751013 | Targeting oncogenic serine/threonine-protein kinase BRAF in cancer cells inhibits angiogenesis and abrogates hypoxia |
Q37847584 | Targeting p27Kip1 protein: its relevance in the therapy of human cancer. |
Q35987779 | Targeting protein kinases in cancer therapy: a success? |
Q37600910 | Targeting the EGF receptor ectodomain in the context of cancer |
Q39047294 | Targeting the EGFR T790M mutation in non-small-cell lung cancer |
Q34246558 | Targeting the EGFR signaling pathway in cancer therapy |
Q91329983 | Targeting the IL-1β/EHD1/TUBB3 axis overcomes resistance to EGFR-TKI in NSCLC |
Q37792116 | Targeting the MET oncogene in cancer and metastases. |
Q37265126 | Targeting the PI3-kinase/Akt/mTOR signaling pathway |
Q29618155 | Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer |
Q33584823 | Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe |
Q37485865 | Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges. |
Q37076172 | Targeting the epidermal growth factor receptor in high-grade astrocytomas |
Q36858198 | Targeting the epidermal growth factor receptor in non-small-cell lung cancer: who, which, when, and how? |
Q37990044 | Targeting the epidermal growth factor receptor in solid tumor malignancies. |
Q36564975 | Targeting the epidermal growth factor receptor in the treatment of colorectal cancer: state of the art. |
Q90138425 | Targeting the evolution of drug resistance in lung cancer |
Q37863629 | Targeting the growth factors and angiogenesis pathways: small molecules in solid tumors |
Q37862077 | Targeting the human EGFR family in esophagogastric cancer |
Q41830456 | Targeting the miR-200c/LIN28B axis in acquired EGFR-TKI resistance non-small cell lung cancer cells harboring EMT features. |
Q41825773 | Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation. |
Q36472432 | Technology insight: pharmacoproteomics for cancer--promises of patient-tailored medicine using protein microarrays |
Q35876022 | Technology platforms for pharmacogenomic diagnostic assays |
Q35007976 | Telomere length and recurrence risk after curative resection in patients with early-stage non-small-cell lung cancer: a prospective cohort study |
Q36077604 | Temporal resolution of autophosphorylation for normal and oncogenic forms of EGFR and differential effects of gefitinib. |
Q36246336 | Ten years of marketing approvals of anticancer drugs in Europe: regulatory policy and guidance documents need to find a balance between different pressures |
Q64916419 | Test Feasibility of Next-Generation Sequencing Assays in Clinical Mutation Detection of Small Biopsy and Fine Needle Aspiration Specimens. |
Q36280333 | Tetrathiomolybdate mediates cisplatin-induced p38 signaling and EGFR degradation and enhances response to cisplatin therapy in gynecologic cancers |
Q36587373 | The 5 stages of biotechnology management |
Q42143312 | The Antitumor Effect of C-terminus of Hsp70-Interacting Protein via Degradation of c-Met in Small Cell Lung Cancer |
Q47655278 | The Association of Acquired T790M Mutation with Clinical Characteristics after Resistance to First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma |
Q36197375 | The Association of EGFR Mutations with Stage at Diagnosis in Lung Adenocarcinomas |
Q35208501 | The BATTLE to personalize lung cancer prevention through reverse migration |
Q34275011 | The BATTLE trial: personalizing therapy for lung cancer |
Q27010154 | The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics |
Q35800375 | The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients |
Q34763495 | The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy |
Q36939336 | The Clinical Significance of the Insulin-Like Growth Factor-1 Receptor Polymorphism in Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor Mutation |
Q49544424 | The Dawning of Translational Breast Cancer: From Bench to Bedside. |
Q64055489 | The Diagnostic Value of Quantitative CT Analysis of Ground-Glass Volume Percentage in Differentiating Epidermal Growth Factor Receptor Mutation and Subtypes in Lung Adenocarcinoma |
Q37026204 | The Difference of Clinical Characteristics Between Patients With Exon 19 Deletion and Those With L858R Mutation in Nonsmall Cell Lung Cancer |
Q49887941 | The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells. |
Q36154748 | The E3 ubiquitin ligase RNF135 regulates the tumorigenesis activity of tongue cancer SCC25 cells |
Q92640668 | The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma |
Q58605631 | The EGFR T790M mutation is acquired through AICDA-mediated deamination of 5-methylcytosine following TKI treatment in lung cancer |
Q38201344 | The EGFR family: not so prototypical receptor tyrosine kinases |
Q40158764 | The EGFR inhibitor gefitinib suppresses ligand-stimulated endocytosis of EGFR via the early/late endocytic pathway in non-small cell lung cancer cell lines |
Q37365512 | The EGFR tyrosine kinase inhibitors as second-line therapy for EGFR wild-type non-small-cell lung cancer: a real-world study in People's Republic of China |
Q38598710 | The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors |
Q37888326 | The EMT regulator slug and lung carcinogenesis |
Q54498075 | The ERBB network: at last, cancer therapy meets systems biology. |
Q37135372 | The ERBB3 receptor in cancer and cancer gene therapy |
Q40701318 | The Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Molecularly Selected Patients with Non-Small Cell Lung Cancer: A Meta-Analysis of 30 Randomized Controlled Trials |
Q36095650 | The Emergent Landscape of Detecting EGFR Mutations Using Circulating Tumor DNA in Lung Cancer. |
Q37257613 | The ErbB kinase domain: structural perspectives into kinase activation and inhibition |
Q52673453 | The Evolving Landscape of Brain Metastasis. |
Q35835931 | The Evolving Role of Maintenance Therapy Using Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors (EGFR TKIs) in the Management of Advanced Non-Small-Cell Lung Cancer |
Q39829525 | The Frequency of EGFR Mutation in Lung Adenocarcinoma and the Efficacy of Tyrosine Kinase Inhibitor Therapy in a Hungarian Cohort of Patients |
Q35608617 | The Frequency of Epidermal Growth Factor Receptor Mutation of Nonsmall Cell Lung Cancer according to the Underlying Pulmonary Diseases |
Q34558080 | The HER family and cancer: emerging molecular mechanisms and therapeutic targets |
Q35702309 | The Impact of Coexisting Asthma, Chronic Obstructive Pulmonary Disease and Tuberculosis on Survival in Patients with Lung Squamous Cell Carcinoma |
Q28067196 | The Impact of Genomic Profiling for Novel Cancer Therapy--Recent Progress in Non-Small Cell Lung Cancer |
Q36280050 | The Impact of Sequence of Chemotherapy and EGFR-TKI Treatment on Different EGFR Mutation Lung Adenocarcinoma |
Q46861636 | The Impact of Smoking and TP53 mutations in lung adenocarcinoma patients with targetable mutations - the Lung Cancer Mutation Consortium (LCMC2). |
Q39015512 | The Importance of Biopsy in the Era of Molecular Medicine |
Q35778529 | The Jeremiah Metzger Lecture: intelligent design of cancer therapy: trials and tribulations. |
Q39752575 | The LUX-Lung clinical trial program of afatinib for non-small-cell lung cancer |
Q34459097 | The MAPK pathway across different malignancies: a new perspective |
Q34173500 | The Met oncogene and basal-like breast cancer: another culprit to watch out for? |
Q38679301 | The Microenvironment of Lung Cancer and Therapeutic Implications |
Q35078950 | The Molecular Crosstalk between the MET Receptor Tyrosine Kinase and the DNA Damage Response-Biological and Clinical Aspects |
Q41043732 | The Myb-p300 Interaction Is a Novel Molecular Pharmacologic Target |
Q97569221 | The National Lung Matrix Trial of personalized therapy in lung cancer |
Q36316643 | The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer |
Q54388246 | The PCR-invader method (structure-specific 5' nuclease-based method), a sensitive method for detecting EGFR gene mutations in lung cancer specimens; comparison with direct sequencing. |
Q33699378 | The PIK3CA gene as a mutated target for cancer therapy |
Q37838120 | The Pharmacogenetic Rescue of Side-Lined Anticancer Drugs to the Front-Line: Gefitinib as a Case Example |
Q58781611 | The Prognostic Role of Circulating Tumor Cells (CTCs) in Lung Cancer |
Q30009944 | The Rak/Frk tyrosine kinase associates with and internalizes the epidermal growth factor receptor |
Q36535465 | The Role of Adaptive Immunity in the Efficacy of Targeted Cancer Therapies |
Q39316449 | The Role of ErbB Receptors in Infection |
Q37335920 | The Role of PIK3CA Mutations among Lung Adenocarcinoma Patients with Primary and Acquired Resistance to EGFR Tyrosine Kinase Inhibition |
Q92830541 | The Role of Precision Medicine in the Diagnosis and Treatment of Patients with Rare Cancers |
Q38199934 | The Role of STAT3 in Non-Small Cell Lung Cancer |
Q37189951 | The Role of the NF-kappaB Transcriptome and Proteome as Biomarkers in Human Head and Neck Squamous Cell Carcinomas |
Q24649549 | The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP |
Q49963088 | The T790M resistance mutation in EGFR is only found in cfDNA from erlotinib-treated NSCLC patients that harbored an activating EGFR mutation before treatment. |
Q38994746 | The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors |
Q37689252 | The Translational Research Working Group developmental pathway for anticancer agents (drugs or biologics). |
Q38768030 | The Use of EGFR Tyrosine Kinase Inhibitors in EGFR Wild-Type Non-Small-Cell Lung Cancer |
Q30978835 | The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data |
Q64062553 | The Value of Liquid Biopsies for Guiding Therapy Decisions in Non-small Cell Lung Cancer |
Q42378470 | The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells |
Q40439596 | The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression |
Q38418344 | The apoptotic effect of simvastatin via the upregulation of BIM in nonsmall cell lung cancer cells |
Q37397842 | The aqueous extract of Brucea javanica suppresses cell growth and alleviates tumorigenesis of human lung cancer cells by targeting mutated epidermal growth factor receptor |
Q37709481 | The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations |
Q36533669 | The bioinformatics analysis of miRNAs signatures differentially expressed in HER2(+) versus HER2(-) breast cancers |
Q49826396 | The biology and management of non-small cell lung cancer. |
Q36780601 | The bronchioloalveolar carcinoma and peripheral adenocarcinoma spectrum of diseases. |
Q34342864 | The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2. |
Q34276557 | The cellular origin for malignant glioma and prospects for clinical advancements |
Q37871875 | The challenges of integrating molecular imaging into the optimization of cancer therapy. |
Q39134733 | The changing landscape of clinical trial and approval processes in China. |
Q39037647 | The changing landscape of gynaecological cancer diagnosis: implications for histopathological practice in the 21st century |
Q92644598 | The combination of bevacizumab/Avastin and erlotinib/Tarceva is relevant for the treatment of metastatic renal cell carcinoma: the role of a synonymous mutation of the EGFR receptor |
Q28268061 | The concept of synthetic lethality in the context of anticancer therapy |
Q37077933 | The content of mutant EGFR DNA correlates with response to EGFR-TKIs in lung adenocarcinoma patients with common EGFR mutations |
Q34622547 | The contribution of cetuximab in the treatment of recurrent and/or metastatic head and neck cancer |
Q50050305 | The detection of EGFR mutation status in plasma is reproducible and can dynamically predict the efficacy of EGFR-TKI. |
Q38907580 | The development of biomarkers to reduce attrition rate in drug discovery focused on oncology and central nervous system |
Q38233179 | The diagnosis and treatment of brain metastases in EGFR mutant lung cancer. |
Q90843191 | The diagnosis of non-small cell lung cancer in the molecular era |
Q26781159 | The distinctive nature of adenocarcinoma of the lung |
Q90728910 | The ectopic expression of meiCT genes promotes meiomitosis and may facilitate carcinogenesis |
Q39425405 | The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model. |
Q86183346 | The effects of ketoconazole and rifampin on the single-dose pharmacokinetics of crizotinib in healthy subjects |
Q35164824 | The efficacy and safety of EGFR inhibitor monotherapy in non-small cell lung cancer: a systematic review |
Q39314771 | The efficacy and safety of nivolumab in previously treated advanced non-small-cell lung cancer: a meta-analysis of prospective clinical trials |
Q53165144 | The efficacy of first-line chemotherapy is associated with KRAS mutation status in patients with advanced non-small cell lung cancer: a meta-analysis. |
Q99365521 | The efficacy of first-line tyrosine kinase inhibitors combined with co-medications in Asian patients with EGFR mutation non-small cell lung cancer |
Q37996424 | The emerging role of ALK inhibitors in the treatment of advanced non-small cell lung cancer |
Q64078507 | The emerging role of cell-free DNA as a molecular marker for cancer management |
Q90481899 | The emerging role of circulating tumor cells in cancer management |
Q35076292 | The emerging role of epidermal growth factor receptor (EGFR) inhibitors in first-line treatment for patients with advanced non-small cell lung cancer positive for EGFR mutations |
Q34343043 | The emerging role of nimotuzumab in the treatment of non-small cell lung cancer |
Q42643276 | The emerging roles of NGS-based liquid biopsy in non-small cell lung cancer |
Q92221532 | The emerging treatment landscape of targeted therapy in non-small-cell lung cancer |
Q38697702 | The enhanced tumor inhibitory effects of gefitinib and L-ascorbic acid combination therapy in non-small cell lung cancer cells |
Q40323538 | The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events |
Q35196749 | The epidermal growth factor receptor (EGRF) in lung cancer |
Q35876412 | The epidermal growth factor receptor as a target for gastrointestinal cancer therapy |
Q34692233 | The epidermal growth factor receptor family: biology driving targeted therapeutics |
Q36268324 | The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what's genetics got to do with it? |
Q55147369 | The era of precision oncogenomics. |
Q44486103 | The estimation of tumor cell percentage for molecular testing by pathologists is not accurate |
Q37953478 | The evolution of phase I trials in cancer medicine: a critical review of the last decade |
Q34852043 | The evolving genomic classification of lung cancer |
Q37046861 | The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma |
Q37389768 | The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer |
Q30539397 | The frequency of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC): routine screening data for central Europe from a cohort study |
Q36606755 | The future in diagnosis and staging of lung cancer. Molecular techniques |
Q38151562 | The genetic complexity of common cancers and the promise of personalized medicine: is there any hope? |
Q33389608 | The genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean population |
Q36605965 | The genetics of health |
Q41891513 | The genomics of lung adenocarcinoma: opportunities for targeted therapies |
Q35124798 | The global landscape of intron retentions in lung adenocarcinoma |
Q39648363 | The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking |
Q34057608 | The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain |
Q29619884 | The impact of O2 availability on human cancer |
Q90532509 | The impact of PRDX4 and the EGFR mutation status on cellular proliferation in lung adenocarcinoma |
Q36872857 | The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma |
Q26741041 | The impact of epidermal growth factor receptor mutations on patterns of disease recurrence after chemoradiotherapy for locally advanced non-small cell lung cancer: a literature review and pooled analysis |
Q64098196 | The impact of epidermal growth factor receptor mutations on the prognosis of resected non-small cell lung cancer: a meta-analysis of literatures |
Q36303828 | The impact of epidermal-growth-factor-receptor mutations in response to lung-cancer therapy |
Q37304354 | The impact of genomic changes on treatment of lung cancer |
Q38822314 | The impact of immunohistochemistry on the classification of lung tumors. |
Q36927984 | The impact of initial gefitinib or erlotinib versus chemotherapy on central nervous system progression in advanced non-small cell lung cancer with EGFR mutations |
Q37536556 | The impact of intermittent versus continuous exposure to EGFR tyrosine kinase inhibitor on selection of EGFR T790M-mutant drug-resistant clones in a lung cancer cell line carrying activating EGFR mutation |
Q54271001 | The impact of rare EGFR mutations on the treatment response of patients with non-small cell lung cancer. |
Q80833899 | The impact of systems approaches on biological problems in drug discovery |
Q38587521 | The importance of molecular markers for diagnosis and selection of targeted treatments in patients with cancer |
Q36040638 | The importance of multidisciplinary team management of patients with non-small-cell lung cancer |
Q39148511 | The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations |
Q84230583 | The influence of intracellular epidermal growth factor receptor (EGFR) signal activation on the outcome of EGFR tyrosine kinase inhibitor treatment for pulmonary adenocarcinoma |
Q52651786 | The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance. |
Q51689988 | The inverted pyramid of biomarker-driven trials. |
Q26823305 | The latest therapeutic strategies after resistance to first generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) in patients with non-small cell lung cancer (NSCLC) |
Q35568803 | The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression |
Q40169126 | The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272. |
Q37976416 | The management of EGFR inhibitor adverse events: a case series and treatment paradigm |
Q36348036 | The mannose-binding lectin: a prototypic pattern recognition molecule |
Q38726762 | The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR. |
Q37022191 | The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients |
Q39899686 | The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors |
Q53512510 | The molecular approach to diagnosis in lung cancer. |
Q37703901 | The molecular genetic basis of ovarian cancer and its roadmap towards a better treatment |
Q42583219 | The need for an individual approach to lung cancer treatment |
Q38292875 | The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer |
Q26998894 | The next steps in next-gen sequencing of cancer genomes |
Q37672566 | The next-generation sequencing revolution and its impact on genomics |
Q42360041 | The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive |
Q50237958 | The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor. |
Q89497176 | The optional approach of oncogene-addicted non-small cell lung cancer with brain metastases in the new generation targeted therapies era |
Q35870933 | The pan-HDAC inhibitor panobinostat acts as a sensitizer for erlotinib activity in EGFR-mutated and -wildtype non-small cell lung cancer cells |
Q36545226 | The pan-HER family tyrosine kinase inhibitor afatinib overcomes HER3 ligand heregulin-mediated resistance to EGFR inhibitors in non-small cell lung cancer |
Q45288154 | The pathologist and EGFR in 2004: I like you, nor do it |
Q54306159 | The peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based test for epidermal growth factor receptor mutations in bronchoscopic cytological specimens of non-small cell lung cancer. |
Q33693948 | The percentage of Epidermal Growth Factor Receptor (EGFR)-mutated neoplastic cells correlates to response to tyrosine kinase inhibitors in lung adenocarcinoma. |
Q36752662 | The pharmacogenetics research network: from SNP discovery to clinical drug response. |
Q54560801 | The phosphatase inhibitor menadione (vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab. |
Q45671065 | The polymorphism of EGFR 142285G > A exerts no risk effect on breast cancer |
Q34480697 | The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells |
Q57283047 | The positive inotropic agent DPI-201106 selectively reverses ABCB1-mediated multidrug resistance in cancer cell lines |
Q28072144 | The possibility of clinical sequencing in the management of cancer |
Q38632346 | The potential diagnostic power of circulating tumor cell analysis for non-small-cell lung cancer |
Q37194315 | The potential role of pharmacogenomic and genomic in the adjuvant treatment of early stage non small cell lung cancer |
Q89927858 | The prognostic factors of recurrence and survival in female patients with lung adenocarcinoma and breast cancer |
Q92869196 | The prognostic implications of EGFR mutation and ALK rearrangement for the long-term outcomes of patients with resected lung adenocarcinomas |
Q41612540 | The prognostic role of pretreatment epidermal growth factor receptor T790M mutation in advanced non-small cell lung cancer patients treated with EGFR tyrosine kinase inhibitors |
Q28282889 | The promise and perils of 'targeted therapy' of advanced ovarian cancer |
Q38981780 | The prospect of patritumab for treating non-small cell lung cancer |
Q39272353 | The protein tyrosine phosphatase receptor type J is regulated by the pVHL-HIF axis in clear cell renal cell carcinoma |
Q33725976 | The quest to overcome resistance to EGFR-targeted therapies in cancer |
Q35151853 | The relationship between TTF-1 expression and EGFR mutations in lung adenocarcinomas |
Q54675285 | The relationship between drug exposure and clinical outcomes of non-small cell lung cancer patients treated with gefitinib. |
Q92798542 | The relationship between preliminary efficacy and prognosis after first-line EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment of advanced non-small cell lung cancer |
Q55439654 | The relationship between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase, excision repair cross-complementation group 1 and class III β-tubulin, and the therapeutic effect of S-1 or carbopla |
Q34918878 | The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors |
Q38089953 | The relevance of molecular diagnostics in the practice of surgical pathology. |
Q38976895 | The reverse effect of X-ray irradiation on acquired gefitinib resistance in non-small cell lung cancer cell line NCI-H1975 in vitro |
Q50345037 | The rise of genomic profiling in ovarian cancer. |
Q39028181 | The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer |
Q34349389 | The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics |
Q37868445 | The role of LKB1 in lung cancer |
Q36704645 | The role of STATs in lung carcinogenesis: an emerging target for novel therapeutics |
Q36561648 | The role of companion diagnostics in the development and use of mutation-targeted cancer therapies |
Q42095201 | The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants |
Q33274011 | The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target |
Q35667688 | The role of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of advanced stage non-small cell lung cancer |
Q35043066 | The role of epigenetics in personalized medicine: challenges and opportunities |
Q26749110 | The role of epithelial to mesenchymal transition in resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer |
Q28397662 | The role of estrogen, progesterone and aromatase in human non-small-cell lung cancer |
Q35602147 | The role of funding and policies on innovation in cancer drug development |
Q51757887 | The role of gefitinib treatment for Korean never-smokers with advanced or metastatic adenocarcinoma of the lung: a prospective study. |
Q37715991 | The role of irreversible EGFR inhibitors in the treatment of non-small cell lung cancer: overcoming resistance to reversible EGFR inhibitors |
Q27021738 | The role of irreversible HER family inhibition in the treatment of patients with non-small cell lung cancer |
Q33779663 | The role of metabolic tumor volume (MTV) measured by [18F] FDG PET/CT in predicting EGFR gene mutation status in non-small cell lung cancer |
Q26825678 | The role of obesity in gastrointestinal cancer: evidence and opinion |
Q36463971 | The role of pharmacoethnicity in the development of cytotoxic and molecular targeted drugs in oncology |
Q37430412 | The role of pharmacogenetics and pharmacogenomics in improving translational medicine. |
Q36536674 | The role of pharmacogenetics in cancer therapeutics |
Q39996855 | The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo[a]pyrene in human lung cancer. |
Q28068169 | The role of surgical intervention in lung cancer with carcinomatous pleuritis |
Q38085500 | The role of tumour-stromal interactions in modifying drug response: challenges and opportunities |
Q58741629 | The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications |
Q37085219 | The safety and efficacy of osimertinib for the treatment of EGFR T790M mutation positive non-small-cell lung cancer |
Q39337947 | The safety and efficacy of ramucirumab in combination with docetaxel in the treatment of lung cancer |
Q50782338 | The second annual symposium on the future of lung cancer: a translational focus. 11-12 November 2005, Washington D.C., USA. |
Q82498098 | The second wave in kinase cancer drugs |
Q38704952 | The selective c-Met inhibitor tepotinib can overcome epidermal growth factor receptor inhibitor resistance mediated by aberrant c-Met activation in NSCLC models |
Q36839141 | The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors |
Q26746895 | The steady progress of targeted therapies, promising advances for lung cancer |
Q44968164 | The story of gefitinib, an EGFR kinase that works in lung cancer |
Q35256540 | The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer |
Q89456689 | The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas |
Q47214772 | The synergistic role of ATP-dependent drug efflux pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer. |
Q96231168 | The top 100 cited articles in lung cancer - a bibliometric analysis |
Q36446457 | The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma |
Q36354852 | The transcriptional landscape and mutational profile of lung adenocarcinoma. |
Q33772611 | The translation of cancer genomics: time for a revolution in clinical cancer care |
Q43128868 | The treatment of metastatic non-small cell lung cancer in a new era of personalized medicine |
Q28534476 | The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner |
Q36928853 | The use of EGFR exon 19 and 21 unlabeled DNA probes to screen for activating mutations in non-small cell lung cancer |
Q37177597 | The use of first-generation tyrosine kinase inhibitors in patients with NSCLC and somatic EGFR mutations |
Q87345449 | The use of mutation-specific antibodies in predicting the effect of EGFR-TKIs in patients with non-small-cell lung cancer |
Q35829847 | The use of single-agent dasatinib in molecularly unselected non-small-cell lung cancer patients |
Q33689655 | The utility of napsin-A in the identification of primary and metastatic lung adenocarcinoma among cytologically poorly differentiated carcinomas |
Q83153095 | The wind of change in the therapy of lung cancer |
Q37755154 | Theme: oncology--molecular mechanisms determining the efficacy of EGF receptor-specific tyrosine kinase inhibitors help to identify biomarker candidates |
Q48100116 | Theoretical method for evaluation of therapeutic effects and adverse effects of epidermal growth factor receptor tyrosine kinase inhibitors in clinical treatment. |
Q26824717 | Theragnostic imaging using radiolabeled antibodies and tyrosine kinase inhibitors |
Q37632230 | Therapeutic approach to treating patients with BRAF-mutant lung cancer: latest evidence and clinical implications |
Q28187576 | Therapeutic approaches in arterial thrombosis |
Q36429446 | Therapeutic potential of EGFR-related protein, a universal EGFR family antagonist |
Q38172182 | Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks |
Q27011293 | Therapeutic strategy for postoperative recurrence in patients with non-small cell lung cancer |
Q35986801 | Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations |
Q36158717 | Therapeutic targeting of receptor tyrosine kinases in lung cancer |
Q35976350 | Therapeutic targets for antimetastatic therapy |
Q36562233 | Therapeutic targets in melanoma: map kinase pathway |
Q35918439 | Therapy for recurrent malignant glioma in adults |
Q40462770 | Therapy's Shadow: A Short History of the Study of Resistance to Cancer Chemotherapy. |
Q33740707 | Third-Generation Tyrosine Kinase Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer |
Q92134589 | Third-generation epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer |
Q33302913 | Thirty years into the genomics era: tumor viruses led the way. |
Q50133191 | Thoracic Complications of Precision Cancer Therapies: A Practical Guide for Radiologists in the New Era of Cancer Care. |
Q54570755 | Three cheers for targeted therapy in non-small cell lung cancer... When we hit the target! |
Q39090203 | Three-color crystal digital PCR. |
Q39813810 | Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death |
Q39290667 | Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance |
Q36050719 | Throwing new light on lung cancer pathogenesis: updates on three recent topics |
Q51750277 | Thymosin alpha1 as a chemopreventive agent in lung and breast cancer. |
Q35076227 | Thyroid cancer: emerging role for targeted therapies |
Q36065174 | Thyroid transcription factor-1 expression is significantly associated with mutations in exon 21 of the epidermal growth factor receptor gene in Chinese patients with lung adenocarcinoma. |
Q43056665 | Time for molecularly targeted maintenance therapy for non-small-cell lung cancer? |
Q58128825 | Time to give a rest to cetuximab in the treatment of advanced non-small cell lung carcinoma? |
Q53313789 | Timeline: Chemotherapy and the war on cancer. |
Q36141341 | Tissue biomarkers for prostate cancer radiation therapy |
Q34323926 | Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer. |
Q37586979 | Tissue specificity in the nuclear envelope supports its functional complexity. |
Q34006509 | Tissue-specific gene expression templates for accurate molecular characterization of the normal physiological states of multiple human tissues with implication in development and cancer studies |
Q37109569 | Tobacco Smoking and Lung Cancer: Perception-changing facts |
Q39784247 | Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice |
Q37701499 | Total DNA input is a crucial determinant of the sensitivity of plasma cell-free DNA EGFR mutation detection using droplet digital PCR. |
Q40393934 | Total and mutated EGFR quantification in cell-free DNA from non-small cell lung cancer patients detects tumor heterogeneity and presents prognostic value |
Q36472802 | Toward personalized cancer nanomedicine - past, present, and future |
Q37972865 | Towards clinical applications of selected reaction monitoring for plasma protein biomarker studies |
Q35897673 | Towards pathway-centric cancer therapies via pharmacogenomic profiling analysis of ERK signalling pathway |
Q34978252 | Towards personalized therapy for patients with glioblastoma |
Q42178081 | Toxicity profile of epidermal growth factor receptor tyrosine kinase inhibitors in patients with epidermal growth factor receptor gene mutation-positive lung cancer |
Q35889315 | Tracking Down Response and Resistance to TRK Inhibitors |
Q37688667 | Trajectory of chemotherapy for patients with EGFR wild-type advanced pulmonary adenocarcinoma: a single-institution retrospective study |
Q30436756 | Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor |
Q33306709 | Transcriptional profiling of non-small cell lung cancer cells with activating EGFR somatic mutations |
Q24653386 | Transcriptome sequencing to detect gene fusions in cancer |
Q58116294 | Transcriptomic and functional network features of lung squamous cell carcinoma through integrative analysis of GEO and TCGA data |
Q51733149 | Transformation to small-cell lung cancer following treatment with icotinib in a patient with lung adenocarcinoma. |
Q93188555 | Transglutaminase 2 induces intrinsic EGFR-TKI resistance in NSCLC harboring EGFR sensitive mutations |
Q22241760 | Translatability scoring in drug development: eight case studies |
Q35694365 | Translating cancer 'omics' to improved outcomes |
Q36411676 | Translating genomic biomarkers into clinically useful diagnostics |
Q36354845 | Translating genomic information into clinical medicine: lung cancer as a paradigm |
Q37127235 | Translating insights from the cancer genome into clinical practice |
Q38114641 | Translating next generation sequencing to practice: opportunities and necessary steps |
Q43010001 | Translating research into cancer molecular diagnostics and patents |
Q34344855 | Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective |
Q24806201 | Translation research: from accurate diagnosis to appropriate treatment |
Q42922307 | Translational Bioinformatics Approaches to Drug Development |
Q38257126 | Translational research in oncology--10 years of progress and future prospects |
Q46544726 | Translational research: the full cycle |
Q35977396 | Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor. |
Q37392560 | Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts |
Q43195737 | Treating acquired resistance to EGFR-tyrosine kinase inhibitors:still a work in progress. |
Q34494115 | Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer |
Q37698613 | Treatment choice in epidermal growth factor receptor mutation-positive non-small cell lung carcinoma: latest evidence and clinical implications. |
Q38739807 | Treatment modalities for advanced ALK-rearranged non-small-cell lung cancer |
Q50104127 | Treatment of EGFR T790M-Positive Non-Small Cell Lung Cancer. |
Q40244548 | Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux) results in paradox phosphorylation of tyrosine 1173 in the receptor |
Q35623614 | Treatment of Non-Small-Cell Lung Cancer with Erlotinib following Gefitinib-Induced Hepatotoxicity: Review of 8 Clinical Cases |
Q37011144 | Treatment of Non-small Cell Lung Carcinoma after Failure of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor |
Q35667817 | Treatment of advanced non small cell lung cancer |
Q59872738 | Treatment of brain metastasis from lung cancer |
Q36185627 | Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling |
Q87296355 | Treatment of non-small cell lung cancer, advanced disease, with erlotinib in 2(nd) and 3(rd) lines. Two cases report |
Q37354440 | Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy |
Q37218978 | Treatment of recurrent metastatic head and neck cancer: focus on cetuximab |
Q53547530 | Treatment of squamous cell vulvar cancer with the anti-EGFR tyrosine kinase inhibitor Tarceva. |
Q36412597 | Treatment of stage IV non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines |
Q35583860 | Treatment of unresectable and metastatic cutaneous squamous cell carcinoma |
Q92895800 | Treatment outcome and clinical characteristics of HER2 mutated advanced non-small cell lung cancer patients in China |
Q40071770 | Treatment schedule is of importance when gefitinib is combined with irradiation of glioma and endothelial cells in vitro |
Q95282127 | Trial Design and Endpoints in hepatocellular carcinoma: AASLD Consensus Conference |
Q36038408 | Trial Watch: Monoclonal antibodies in cancer therapy |
Q56932681 | Trial watch: Monoclonal antibodies in cancer therapy |
Q35970324 | Trial-Based Cost-Utility Analysis of Icotinib versus Gefitinib as Second-Line Therapy for Advanced Non-Small Cell Lung Cancer in China |
Q24564024 | Trials to Overcome Drug Resistance to EGFR and ALK Targeted Therapies - Past, Present, and Future |
Q37204363 | Trichomegaly and scalp hair changes following treatment with erlotinib in pulmonary adenocarcinoma patients: A case report and literature review |
Q34041747 | Triple inhibition of EGFR, Met, and VEGF suppresses regrowth of HGF-triggered, erlotinib-resistant lung cancer harboring an EGFR mutation |
Q37594358 | Triple negative breast carcinoma EGFR amplification is not associated with EGFR, Kras or ALK mutations |
Q36747692 | Triple-negative breast cancer: therapeutic options |
Q36048159 | Tumor Hypoxia Response After Targeted Therapy in EGFR-Mutant Non-Small Cell Lung Cancer: Proof of Concept for FMISO-PET. |
Q36439444 | Tumor MET expression profile predicts the outcome of non-small cell lung cancer patients receiving epidermal growth factor receptor tyrosine kinase inhibitors. |
Q37548937 | Tumor dormancy and metastasis. |
Q36616513 | Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth |
Q36196817 | Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma. |
Q35584773 | Tumor epidermal growth factor receptor genotype and depression in stage IV non-small cell lung cancer |
Q97538366 | Tumor evolution in epidermal growth factor receptor mutated non-small cell lung cancer |
Q38192631 | Tumor heterogeneity in the clinic: is it a real problem? |
Q38390044 | Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients |
Q91774076 | Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors |
Q45204330 | Tumor response to gefitinib (IRESSA) in pulmonary adenocarcinoma: toward a molecular basis for therapeutic targetting |
Q37021940 | Tumor volume decrease at 8 weeks is associated with longer survival in EGFR-mutant advanced non-small-cell lung cancer patients treated with EGFR TKI. |
Q39839864 | Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17. |
Q89579304 | Tumour content ratio matters for detecting epidermal growth factor receptor mutation by cobas test in small biopsies; a retrospective study |
Q58599910 | Tumour-targeting bacteria engineered to fight cancer |
Q89651597 | Turning liabilities into opportunities: Off-target based drug repurposing in cancer |
Q35896601 | Two sides of the same coin: EGFR exon 19 deletions and insertions in lung cancer |
Q36022297 | Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer |
Q26741318 | Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications |
Q46590868 | Tyrosine kinase activating mutations in human malignancies: implications for diagnostic pathology |
Q37712380 | Tyrosine kinase domain mutations of EGFR gene in head and neck squamous cell carcinoma. |
Q37894095 | Tyrosine kinase inhibitors for non-small-cell lung cancer: finding patients who will be responsive |
Q35908430 | Tyrosine kinase inhibitors in lung cancer |
Q36977823 | Tyrosine kinase inhibitors in pediatric malignancies |
Q34983846 | Tyrosine kinase inhibitors: Multi-targeted or single-targeted? |
Q37408903 | Tyrosine phosphorylation: thirty years and counting |
Q92840636 | UBE2T silencing inhibited non-small cell lung cancer cell proliferation and invasion by suppressing the wnt/β-catenin signaling pathway |
Q58577633 | USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells |
Q39962704 | Ultra-micro samples can be used for mRNA quantification of lung cancer biomarkers. |
Q36185551 | Ultrasensitive measurement of hotspot mutations in tumor DNA in blood using error-suppressed multiplexed deep sequencing. |
Q48128121 | Uncommon frame-shift exon 19 EGFR mutations are sensitive to EGFR tyrosine kinase inhibitors in non-small cell lung carcinoma. |
Q39002233 | Understanding Mechanisms of Resistance in the Epithelial Growth Factor Receptor in Non-Small Cell Lung Cancer and the Role of Biopsy at Progression |
Q46915997 | Understanding and targeting resistance mechanisms in NSCLC. |
Q34088424 | Understanding resistance to EGFR inhibitors-impact on future treatment strategies |
Q27691330 | Understanding the Impact of ErbB Activating Events and Signal Transduction on Antigen Processing and Presentation: MHC Expression as a Model |
Q28546245 | Understanding the Interplay between Expression, Mutation and Activity of ALK Receptor in Rhabdomyosarcoma Cells for Clinical Application of Small-Molecule Inhibitors |
Q52648399 | Underutilization and disparities in access to EGFR testing among Medicare patients with lung cancer from 2010 - 2013. |
Q46787342 | Unexpected rapid progression of metastatic adenoid cystic carcinoma during treatment with imatinib mesylate. |
Q37039734 | Unifying electrostatic mechanism for phosphates and sulfates in cell signaling |
Q33833942 | Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population |
Q81831688 | Unique issues in the development of "targeted" antineoplastic pharmaceutical agents |
Q40344816 | Unique prevalence of oncogenic genetic alterations in young patients with lung adenocarcinoma |
Q36173303 | Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer |
Q60044591 | Up-Regulated FGFR1 Expression as a Mediator of Intrinsic TKI Resistance in EGFR-Mutated NSCLC |
Q37443898 | Update in antiepidermal growth factor receptor therapy in the management of metastatic colorectal cancer. |
Q36429911 | Update in lung cancer 2005. |
Q36796569 | Update in lung cancer 2006 |
Q35667802 | Update on anti-angiogenic therapy in non-small cell lung cancer: Are we making progress? |
Q61810147 | Update on emerging biomarkers in lung cancer |
Q50802132 | Update on epidermal growth factor receptor inhibitor development in lung cancer. |
Q38237463 | Update on systemic therapy of advanced non-small-cell lung cancer |
Q37721218 | Update on the Treatment of Metastatic Squamous Non-Small Cell Lung Cancer in New Era of Personalized Medicine |
Q44701539 | Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin-paclitaxel for chemo-naïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002). |
Q89485969 | Upfront radiosurgery plus targeted agents followed by active brain control using radiosurgery delays neurological death in non-small cell lung cancer with brain metastasis |
Q91845232 | Urinary Epidermal Growth Factor as a Marker of Disease Progression in Children With Nephrotic Syndrome |
Q48604114 | Urinary circulating DNA detection for dynamic tracking of EGFR mutations for NSCLC patients treated with EGFR-TKIs. |
Q47564108 | Urine test for EGFR analysis in patients with non-small cell lung cancer |
Q37779308 | Use of K-Ras as a predictive biomarker for selecting anti-EGF receptor/pathway treatment |
Q33859472 | Use of Nanotechnology to Develop Multi-Drug Inhibitors For Cancer Therapy |
Q89560168 | Use of a plasma test for verifying epidermal growth factor receptor gene (EGFR) mutations in fluid samples from non-small cell lung cancer patients |
Q37630180 | Use of a tyrosine kinase inhibitor as neoadjuvant therapy for non-small cell lung cancer: A case report. |
Q37269473 | Use of dedicated gene panel sequencing using next generation sequencing to improve the personalized care of lung cancer |
Q57556407 | Use of genome-wide high-throughput technologies in biomarker development |
Q36369836 | Use of genomic signatures in therapeutics development in oncology and other diseases |
Q30585673 | Use of multiple imputation to correct for bias in lung cancer incidence trends by histologic subtype |
Q34003351 | Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review. |
Q27022535 | Use of the epidermal growth factor receptor inhibitors gefitinib, erlotinib, afatinib, dacomitinib, and icotinib in the treatment of non-small-cell lung cancer: a systematic review |
Q52723939 | Usefulness of Bronchoscopic Rebiopsy of Non-Small Cell Lung Cancer with Acquired Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor. |
Q54586663 | Usefulness of EGFR mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer. |
Q24813486 | Ushering in the new toxicology: toxicogenomics and the public interest |
Q55182205 | Using Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways. |
Q28476059 | Using expression and genotype to predict drug response in yeast |
Q35829133 | Using germ-line genetic variation to investigate and treat cancer |
Q31038214 | Using high-throughput sequencing transcriptome data for INDEL detection: challenges for cancer drug discovery. |
Q34474427 | Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer. |
Q34175045 | Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs |
Q35602598 | Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib |
Q37354097 | Using the theory of coevolution to predict protein-protein interactions in non-small cell lung cancer. |
Q38679628 | Utility of Genomic Assessment of Blood-Derived Circulating Tumor DNA (ctDNA) in Patients with Advanced Lung Adenocarcinoma |
Q54390545 | Utilization of cell-transferred cytologic smears in detection of EGFR and KRAS mutation on adenocarcinoma of lung. |
Q37238134 | Utilization of epidermal growth factor receptor (EGFR) testing in the United States: a case study of T3 translational research |
Q37301478 | VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab |
Q37393004 | VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy |
Q52803546 | Validation and comparison of two NGS assays for the detection of EGFR T790M resistance mutation in liquid biopsies of NSCLC patients. |
Q89985173 | Validation and implementation of a modular targeted capture assay for the detection of clinically significant molecular oncology alterations |
Q41906700 | Validation and implementation of targeted capture and sequencing for the detection of actionable mutation, copy number variation, and gene rearrangement in clinical cancer specimens |
Q92989775 | Validation of Immunohistochemistry for the Detection of BRAF V600E-Mutated Lung Adenocarcinomas |
Q54118788 | Validation of [18F]FLT as a perfusion-independent imaging biomarker of tumour response in EGFR-mutated NSCLC patients undergoing treatment with an EGFR tyrosine kinase inhibitor. |
Q41331019 | Validation of a locked nucleic acid based wild-type blocking PCR for the detection of EGFR exon 18/19 mutations |
Q34231456 | Validation of a multiparameter flow cytometry method for the determination of phosphorylated extracellular-signal-regulated kinase and DNA in circulating tumor cells |
Q35663913 | Validation of an Ion Torrent Sequencing Platform for the Detection of Gene Mutations in Biopsy Specimens from Patients with Non-Small-Cell Lung Cancer |
Q80731960 | Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma |
Q48502619 | Validation of liquid biopsy: plasma cell-free DNA testing in clinical management of advanced non-small cell lung cancer. |
Q34903217 | Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis |
Q87928043 | Value of ¹⁸F-FDG uptake on PET/CT and CEA level to predict epidermal growth factor receptor mutations in pulmonary adenocarcinoma |
Q37177871 | Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma |
Q38016190 | Vandetanib for the treatment of lung cancer |
Q39203869 | Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial |
Q39218984 | Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency |
Q42598308 | VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research |
Q38731617 | Variability in Platelet-Derived Growth Factor Receptor Alpha Antibody Specificity May Impact Clinical Utility of Immunohistochemistry Assays |
Q36615850 | Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors. |
Q35456811 | Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial. |
Q36691776 | Vascular endothelial growth factor pharmacogenetics: a new perspective for anti-angiogenic therapy |
Q35122066 | Very low prevalence of epidermal growth factor receptor (EGFR) protein expression and gene amplification in Saudi breast cancer patients. |
Q35387710 | Virotherapy induces massive infiltration of neutrophils in a subset of tumors defined by a strong endogenous interferon response activity |
Q57521562 | Visceral obesity, metabolic syndrome, insulin resistance and cancer |
Q36553854 | Volumetric Tumor Response and Progression in EGFR-mutant NSCLC Patients Treated with Erlotinib or Gefitinib |
Q37280018 | Volumetric tumor growth in advanced non-small cell lung cancer patients with EGFR mutations during EGFR-tyrosine kinase inhibitor therapy: developing criteria to continue therapy beyond RECIST progression |
Q37001330 | Von Hippel-Lindau tumor suppressor gene loss in renal cell carcinoma promotes oncogenic epidermal growth factor receptor signaling via Akt-1 and MEK-1 |
Q36427381 | Whacking a mole-cule: clinical activity and mechanisms of resistance to third generation EGFR inhibitors in EGFR mutated lung cancers with EGFR-T790M. |
Q35927471 | What are the reasons for negative phase III trials of molecular-target-based drugs? |
Q34213994 | What are we learning from the cancer genome? |
Q38312059 | What is the best strategy for targeting EGF receptors in non-small-cell lung cancer? |
Q46787079 | What is the best way to manage patients treated with gefitinib for non-small-cell lung cancer? |
Q48639219 | What is the future for cancer clinical trials? |
Q48241759 | What is the potential of nanolock- and nanocross-nanopore technology in cancer diagnosis? |
Q81352782 | What oncologists need and require from nuclear medicine |
Q24812087 | When clinical trials are compromised: a perspective from a patient advocate |
Q36496065 | Where next for gefitinib in patients with lung cancer? |
Q36610132 | Which biomarker predicts benefit from EGFR-TKI treatment for patients with lung cancer? |
Q44340382 | Which drugs for which patients? |
Q38222703 | Which tyrosine kinase inhibitor should be recommended as initial treatment for non-small cell lung cancer patients with EGFR mutations? |
Q43071284 | Who will take up the gauntlet? Challenges and opportunities for systems biology and drug discovery |
Q28269291 | Whole-genome analysis informs breast cancer response to aromatase inhibition |
Q48431386 | Why Cancer matters. |
Q33304557 | Why do cancer cells become "addicted" to oncogenic epidermal growth factor receptor? |
Q35929119 | Will tomorrow's medicines work for everyone? |
Q37952291 | Winning the arms race by improving drug discovery against mutating targets |
Q34876177 | Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. |
Q38113540 | Worldwide trend of increasing primary adenocarcinoma of the lung |
Q36568760 | Worldwide trends in lung cancer pathology |
Q47097774 | Worse disease-free, tumor-specific, and overall survival in surgically-resected lung adenocarcinoma patients with ALK rearrangement |
Q88682201 | Xenograft tumors derived from malignant pleural effusion of the patients with non-small-cell lung cancer as models to explore drug resistance |
Q41281151 | YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells |
Q37829768 | Year in review 2010: interstitial lung diseases, acute lung injury, sleep, physiology, imaging, bronchoscopic intervention and lung cancer |
Q37624912 | Yin-Cold or Yang-Heat Syndrome Type of Traditional Chinese Medicine Was Associated with the Epidermal Growth Factor Receptor Gene Status in Non-Small Cell Lung Cancer Patients: Confirmation of a TCM Concept |
Q42690204 | Young cancer researchers rewarded |
Q36146882 | ZD6474--clinical experience to date |
Q80403956 | ["Targeted Therapies" in NSCLC - present and future] |
Q54329437 | [A comparison of direct sequencing and ARMS assay performance in EGFR mutation analysis of non-small cell lung cancer patients]. |
Q55436763 | [A study on the long-term non-small cell lung cancer survivors in the Expand Access Program of gefitinib in China]. |
Q55020044 | [Afatinib as first-line therapy in mutation-positive EGFR. Results by type of mutation]. |
Q64884192 | [Anatomy, biology and concepts, pertaining to lung cancer stage classification]. |
Q79317745 | [Anti-EGFR therapy: towards a "à la carte" targeting of hepatocellular carcinoma] |
Q55464970 | [Classification and regression tree analysis of clinical patterns that predict survival in 127 Chinese patients with advanced non-small cell lung cancer treated by gefitinib who failed to previous chemotherapy]. |
Q55464335 | [Classification and regression tree analysis of clinical patterns to predict the survival of patients with advanced non-small cell lung cancer treated with erlotinib]. |
Q53340641 | [Clinical Experience of Gefitinib in the Treatment of 32 Lung Adenocarcinoma Patients with Brain Metastases]. |
Q53520768 | [Clinical Research of EGFR and KRAS Mutation in Fine Needle Aspiration Cytology Specimens of Non-small Cell Lung Carcinoma]. |
Q54389938 | [Clinical significance of ROS1 rearrangements in non-small cell lung cancer]. |
Q54611055 | [Comparison of EGFR mutation status in paired pre- and post-chemotherapy serum for advanced pulmonary adenocarcinoma]. |
Q55437669 | [Development of Precision Medicine in the Surgical Treatment of Lung Cancer]. |
Q54584671 | [Discordance of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in non-small cell lung cancer]. |
Q53654923 | [EGF receptor blockade with monoclonal antibodis and so-called "small molecules"]. |
Q49958940 | [EGFR and KRAS Gene Mutations in 754 Patients with Resectable Stage I-IIIa Non-small Cell Lung Cancer and Its Clinical Significance]. |
Q54482790 | [EGFR gene mutation statuses in advanced non-small cell lung cancer patients and their influence on effect of gefitinib]. |
Q54282828 | [Effectiveness of EGFR-TKIs versus chemotherapy as first-line treatment for advanced non-small cell lung cancer: a meta-analysis]. |
Q54169610 | [Effects of Erlotinib on 34 Patients with Advanced Squamous Cell Lung Cancer]. |
Q55465317 | [Effects of monoclonal antibody cetuximab on proliferation of non-small cell lung cancer cell lines]. |
Q79761419 | [Gefitinib treatment for carcinomatous meningitis in non-small cell lung cancer] |
Q84170796 | [Histology-based algorithm in the molecular diagnosis of mutations of the Epidernal Growth Factor Receptor (EGFR) in non-small cell lung cancer] |
Q55432482 | [Local treatment combined with EGFR-TKIs for advanced non-small cell lung cancer with solitary progression during EGFR-TKI treatment]. |
Q64941333 | [Lung cancer in women: a different entity?]. |
Q80294340 | [Molecular diagnosis and response prediction to anti-tyrosine kinase receptors in oncology] |
Q63979899 | [Molecular diagnostics of lung cancer for treatment stratification] |
Q80606168 | [Molecular high throughput research in prostate carcinoma] |
Q54262588 | [Molecular targeted therapies and cytotoxics: Friends or foes?]. |
Q82663591 | [Multi-targeting drugs and multi-drug targeting in metastatic renal cell carcinoma. Concept of co-inhibition of the epidermal growth] |
Q80212282 | [New biological treatments for lung cancer] |
Q81596236 | [New therapeutic approaches in glioblastomas] |
Q87254396 | [Personalized targeted therapy for lung cancer] |
Q54164031 | [Relationship between EGFR Promoter Region Methylation and Secondary Resistance Which may be Induced by Gefitinib]. |
Q51057061 | [Research Advancement on EGFR Mutation Detection of Cell-free DNA and Tumor Cell in Peripheral Blood of Patients with Non-small Cell Lung Cancer]. |
Q54602050 | [Retreatment with epidermal growth factor receptor inhibitor after initial failure in advanced non-small cell lung cancer]. |
Q54177645 | [Serum CYFRA21-1 is Correlated with the Efficacy of Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor in Non-small Cell Lung Cancer Patients Harboring EGFR Mutations]. |
Q89862647 | [Studies and Progress of EGFR exon 20 Insertion Mutation in Non-small Cell Lung Cancer] |
Q81891643 | [Targeted biotherapies in digestive oncology: a new era in therapeutic management?] |
Q54176392 | [Targeted therapy and precision medicine : More than just words in the treatment of lung cancer]. |
Q55427171 | [The detection methods of EGFR mutations in non-small cell lung cancer]. |
Q80737378 | [Therapeutic management of extensive bronchiolo-alveolar adenocarcinoma: chemotherapy or inhibitors of epidermal growth factor receptor tyrosine kinase?] |
Q80149575 | [Therapy of malignant melanoma. First-, second- and pathogenesis-oriented third-line therapies] |
Q55020040 | [Toxicity associated with EGRF inhibition: review and key aspects in the management of afatinib]. |
Q54484638 | [Translational research and diagnostics in lung cancer]. |
Q54337306 | [Treatment progress for EGFR wild-type advanced non-small cell lung cancer]. |
Q83901136 | [Tyrosine kinase inhibitors in oncology] |
Q35088202 | [¹⁸F]FDG positron emission tomography within two weeks of starting erlotinib therapy can predict response in non-small cell lung cancer patients |
Q53340770 | c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. |
Q35997750 | c-kit expression in adenocarcinomas of the lung. |
Q38304521 | hEGR1 is induced by EGF, inhibited by gefitinib in bladder cell lines and related to EGF receptor levels in bladder tumours |
Q34729796 | mTOR inhibitors control the growth of EGFR mutant lung cancer even after acquiring resistance by HGF. |
Q39165050 | mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy |
Q33774131 | miR-19a contributes to gefitinib resistance and epithelial mesenchymal transition in non-small cell lung cancer cells by targeting c-Met |
Q38366840 | miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells |
Q34136203 | miRNA expression profiling of lung adenocarcinomas: correlation with mutational status |
Q33412928 | nab-paclitaxel for the management of patients with advanced non-small-cell lung cancer |
Q39373570 | p14(ARF) inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway |
Q47136556 | p40 & thyroid transcription factor-1 immunohistochemistry: A useful panel to characterize non-small cell lung carcinoma-not otherwise specified (NSCLC-NOS) category |
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Q40074891 | siRNA mediated the type 1 insulin-like growth factor receptor and epidermal growth factor receptor silencing induces chemosensitization of liver cancer cells. |
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Q64884710 | xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression. |
Q38922926 | γ Secretase inhibitor BMS-708163 reverses resistance to EGFR inhibitor via the PI3K/Akt pathway in lung cancer |
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