Immunotherapy in the Asiatic population: any differences from Caucasian population?

scientific article published in May 2018

Immunotherapy in the Asiatic population: any differences from Caucasian population? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.21037/JTD.2018.05.106
P932PMC publication ID5994501
P698PubMed publication ID29951300

P2093author name stringYi-Long Wu
Lunxi Peng
P2860cites workSafety, Activity, and Immune Correlates of Anti–PD-1 Antibody in CancerQ24633070
Crizotinib resistance: implications for therapeutic strategiesQ26738381
Radiotherapy combination opportunities leveraging immunity for the next oncology practiceQ26738443
Combining radiotherapy and cancer immunotherapy: a paradigm shiftQ27021428
EGFR mutation and resistance of non-small-cell lung cancer to gefitinibQ27824829
Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung CancersQ27851710
Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary CancersQ27853176
PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.Q27853379
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinibQ27861059
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer AgentsQ28087754
Comprehensive molecular profiling of lung adenocarcinomaQ28244995
Cancer statistics, 2016Q29547383
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patientsQ29617771
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancerQ29620301
Pembrolizumab for the treatment of non-small-cell lung cancerQ29620851
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung CancerQ29620902
Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung CancerQ29620913
Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study.Q30275719
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trialQ30277192
Update on the role of ipilimumab in melanoma and first data on new combination therapiesQ30585096
Efficacy and safety of nivolumab in Japanese patients with advanced or recurrent squamous non-small cell lung cancerQ33738921
Ongoing clinical trials of PD-1 and PD-L1 inhibitors for lung cancer in ChinaQ33876861
Safety and antitumour activity of durvalumab plus tremelimumab in non-small cell lung cancer: a multicentre, phase 1b studyQ33880042
A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER)Q34041754
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancerQ35463514
Phase I study of ipilimumab in phased combination with paclitaxel and carboplatin in Japanese patients with non-small-cell lung cancer.Q35817265
Molecular Epidemiology of EGFR Mutations in Asian Patients with Advanced Non-Small-Cell Lung Cancer of Adenocarcinoma Histology - Mainland China Subset Analysis of the PIONEER studyQ35849985
Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung CancerQ36352827
Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1-Selected Advanced Non-Small-Cell Lung Cancer (BIRCH).Q36400381
Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE StudyQ36404761
Phase 1 study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced solid tumorsQ36879415
The global burden of liver disease: the major impact of ChinaQ36901892
Randomized phase I pharmacokinetic study of ipilimumab with or without one of two different chemotherapy regimens in patients with untreated advanced melanomaQ36980597
Mutation incidence and coincidence in non small-cell lung cancer: meta-analyses by ethnicity and histology (mutMap).Q37126929
Model-Based Population Pharmacokinetic Analysis of Nivolumab in Patients With Solid TumorsQ37609786
PD-1 inhibitors increase the incidence and risk of pneumonitis in cancer patients in a dose-independent manner: a meta-analysisQ37685959
Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillanceQ38124438
Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?Q38447992
Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?Q38541770
Potential biomarker for checkpoint blockade immunotherapy and treatment strategy.Q38700735
Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial.Q38760078
Adding checkpoint inhibitors to tyrosine kinase inhibitors targeting EGFR/ALK in non-small cell lung cancer: a new therapeutic strategyQ38827684
EGFR-TKI down-regulates PD-L1 in EGFR mutant NSCLC through inhibiting NF-κB.Q38872276
Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trialQ38906747
Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR MutationQ38912283
The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4.Q38919859
PD-1 checkpoint blockade alone or combined PD-1 and CTLA-4 blockade as immunotherapy for lung cancer?Q39033713
Potential Predictive Value of TP53 and KRAS Mutation Status for Response to PD-1 Blockade Immunotherapy in Lung Adenocarcinoma.Q39048866
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumorsQ39089944
Elements of cancer immunity and the cancer-immune set pointQ39094764
Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study.Q39118471
Estimating the burden of disease attributable to injecting drug use as a risk factor for HIV, hepatitis C, and hepatitis B: findings from the Global Burden of Disease Study 2013.Q39354156
Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trialQ39396355
Nivolumab Monotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung CancerQ39646977
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trialQ40163779
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trialQ40231174
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial.Q40408396
Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy.Q40534742
Change in PD-L1 Expression After Acquiring Resistance to Gefitinib in EGFR-Mutant Non-Small-Cell Lung CancerQ41019077
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer: A Retrospective Analysis.Q41112103
Unique distribution of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancerQ41302377
Nivolumab in Combination With Platinum-Based Doublet Chemotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung CancerQ41508440
PD-1 Axis Inhibitors in EGFR- and ALK-Driven Lung Cancer: Lost Cause?Q42644265
Radiation and immunotherapy: a synergistic combination.Q42724344
Treating KRAS-mutant NSCLC: latest evidence and clinical consequencesQ42820759
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and NeckQ43164702
Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth RateQ43715235
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunityQ46066476
Phase I/II study of ipilimumab for patients with metastatic melanomaQ46087025
P2.39: Long-Term OS for Patients With Advanced NSCLC Enrolled in the KEYNOTE-001 Study of Pembrolizumab: Track: ImmunotherapyQ46888796
EGFR mutation correlates with uninflamed phenotype and weak immunogenicity, causing impaired response to PD-1 blockade in non-small cell lung cancerQ47214499
Clinical and Molecular Characteristics Associated With Survival Among Patients Treated With Checkpoint Inhibitors for Advanced Non-Small Cell Lung Carcinoma: A Systematic Review and Meta-analysisQ47262054
Nivolumab versus everolimus in advanced renal cell carcinoma: Japanese subgroup analysis from the CheckMate 025 studyQ47564905
Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung CancerQ47834638
Tumor immune microenvironment and nivolumab efficacy in EGFR mutation-positive non-small-cell lung cancer based on T790M status after disease progression during EGFR-TKI treatment.Q47920560
Nivolumab versus docetaxel in previously treated advanced non-small cell lung cancer (CheckMate 017 and CheckMate 057): 3-year update and outcomes in patients with liver metastasesQ50161502
Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study.Q50876217
136O: Osimertinib combined with durvalumab in EGFR-mutant non-small cell lung cancer: Results from the TATTON phase Ib trialQ51521616
Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.Q52586557
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung CancerQ52587406
Five-Year Follow-Up of Nivolumab in Previously Treated Advanced Non-Small-Cell Lung Cancer: Results From the CA209-003 StudyQ52640577
57O Efficacy, safety and tolerability of MEDI4736 (durvalumab [D]), a human IgG1 anti-programmed cell death-ligand-1 (PD-L1) antibody, combined with gefitinib (G): A phase I expansion in TKI-naïve patients (pts) with EGFR mutant NSCLC.Q52868409
Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancerQ54339119
Multicentre phase II study of nivolumab in Japanese patients with advanced or recurrent non-squamous non-small cell lung cancer.Q54620120
Update on immune checkpoint inhibitors in lung cancerQ56897146
Non-small cell lung cancerQ59565902
P433issueSuppl 13
P921main subjectimmunotherapyQ1427096
P304page(s)S1482-S1493
P577publication date2018-05-01
P1433published inJournal of thoracic diseaseQ26841814
P1476titleImmunotherapy in the Asiatic population: any differences from Caucasian population?
P478volume10

Reverse relations

cites work (P2860)
Q99582721A meta-analysis on immune checkpoint inhibitor efficacy for advanced non-small cell lung cancer between East Asians versus non-East Asians
Q97537530Genomic assessment distinguishes intrapulmonary metastases from synchronous primary lung cancers
Q89622208KEYNOTE-042 rolls back programmed cell death ligand 1 threshold for non-small cell lung cancer pembrolizumab monotherapy without new insight into those deriving benefit
Q91649938Treatment-Related Adverse Events of Combination Immune Checkpoint Inhibitors: Systematic Review and Meta-Analysis

Search more.