Pharmacogenomics: unlocking the human genome for better drug therapy

scientific article

Pharmacogenomics: unlocking the human genome for better drug therapy is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1146/ANNUREV.PHARMTOX.41.1.101
P698PubMed publication ID11264452
P5875ResearchGate publication ID12069356

P2093author name stringMcLeod HL
Evans WE
P2860cites workDistinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
Systematic variation in gene expression patterns in human cancer cell linesQ28145747
P921main subjectpharmacogenomicsQ1152227
P304page(s)101-121
P577publication date2001-01-01
P1433published inAnnual Review of Pharmacology and ToxicologyQ567365
P1476titlePharmacogenomics: unlocking the human genome for better drug therapy
P478volume41

Reverse relations

cites work (P2860)
Q47149558A 17-molecule set as a predictor of complete response to neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in esophageal cancer
Q46923413An exploratory study of the association of adrenergic and serotonergic genotype and gastrointestinal motor functions
Q46614987Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in Chinese cancer patients
Q35608800Antiarrhythmic drugs: past, present and future
Q38551666Are pharmacogenomic biomarkers an effective tool to predict taxane toxicity and outcome in breast cancer patients? Literature review
Q35065516Between-patient differences in the renal response to renin-angiotensin system intervention: clue to optimising renoprotective therapy?
Q37055326CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel
Q35553873Cancer Pharmacogenomics: SNPs, Chips, and the Individual Patient
Q35078443Cancer pharmacogenomics: current and future applications
Q37191102Challenge for a better combination with basic evidence
Q35188391Chemotherapy individualization.
Q31128049Clinical translation of genotyping and haplotyping data: implementation of in vivo pharmacology experience leading drug prescription to pharmacotyping
Q34612133Comparative genome analysis and pathway reconstruction
Q36335956Concept-based learning of personalized prescribing
Q36474351Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine
Q56887724Current Awareness on Comparative and Functional Genomics
Q35876954Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms
Q27318232Differential Gene Expression across Breed and Sex in Commercial Pigs Administered Fenbendazole and Flunixin Meglumine
Q37627676Docetaxel: its role in current and future treatments for advanced gastric cancer
Q36061821Drug bioactivation, covalent binding to target proteins and toxicity relevance
Q37791284Drug interactions in metastatic breast cancer
Q79768663Drug pathways: moving beyond single gene pharmacogenetics
Q40601170Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine
Q34743306Ethical perspectives on pharmacogenomic profiling in the drug development process
Q36986803Evaluation of cytochrome P450 2C9 activity in normal, healthy, adult Western Indian population by both phenotyping and genotyping
Q33261407Evaluation of the activity of CYP2C19 in Gujrati and Marwadi subjects living in Mumbai (Bombay)
Q57421032Evidence for epistatic interactions in antiepileptic drug resistance
Q34649031Formats for combinatorial synthesis: solid-phase, liquid-phase and surface
Q40585334Future prospects of personalized chemotherapy in gastric cancer patients: results of a prospective randomized pilot study
Q38749453Gene Co-Expression Analysis Predicts Genetic Variants Associated with Drug Responsiveness in Lung Cancer
Q41910462Gene expression biomarkers of response to citalopram treatment in major depressive disorder
Q51988543Genetic association mapping under founder heterogeneity via weighted haplotype similarity analysis in candidate genes.
Q37702926Genetic diversity and medicinal drug response in eye care
Q74551571Genetic polymorphisms of adrenergic receptors
Q35569570Genetic variation and hematology: single-nucleotide polymorphisms, haplotypes, and complex disease
Q34743245Genome-based pharmacogenetics and the pharmaceutical industry
Q35035617Genomics and the prediction of xenobiotic toxicity
Q38192063Global pharmacogenomics: where is the research taking us?
Q34312035Herbal modulation of P-glycoprotein
Q36475069Human genomic diversity, viral genomics and proteomics, as exemplified by human papillomaviruses and H5N1 influenza viruses
Q35070838Human pharmacogenomic variations and their implications for antifungal efficacy
Q44956846Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway
Q37998365Individualized medicine, health medicine, and constitutional theory in Chinese medicine
Q34102297Inducible, pharmacogenetic approaches to the study of learning and memory.
Q34786114Insights into pharmacogenomics and its impact upon immunosuppressive therapy
Q38689857Metabolomics applications in precision medicine: An oncological perspective
Q36811537Methadone-associated long QT syndrome: improving pharmacotherapy for dependence on illegal opioids and lessons learned for pharmacology
Q34836984Microarrays in pharmacogenomics--advances and future promise
Q34670698Molecular aspects of pain research
Q36691738Multiplexing molecular diagnostics and immunoassays using emerging microarray technologies
Q35000912Murine pharmacogenomics: using the mouse to understand the genetics of drug therapy
Q35771333Neonatal exposure to drugs in breast milk
Q34990652New insights in the transcriptional activity and coregulator molecules in the arterial wall
Q36481129Next revolution in the molecular theranostics of infectious diseases: microfabricated systems for personalized medicine
Q35746810Pathophysiology as a basis for understanding symptom complexes and therapeutic targets
Q38100809Personalized diagnostics and biosensors: a review of the biology and technology needed for personalized medicine
Q34581712Pharmaceutical education in the wake of genomic technologies for drug development and personalized medicine
Q38778546Pharmacogenetic Predictors of Response
Q35645901Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing
Q26739350Pharmacogenetic studies update in type 2 diabetes mellitus
Q34481324Pharmacogenetic tactics and strategies: implications for paediatrics
Q36028625Pharmacogenetics and pharmacogenomics as new tools to optimise cancer chemotherapy
Q34586812Pharmacogenetics of Lipid-lowering Therapies
Q23919667Pharmacogenetics, pharmacogenomics, and individualized medicine
Q35976402Pharmacogenetics/pharmacogenomics and antirheumatic drugs in rheumatology.
Q37913989Pharmacogenetics: implications for therapy in rheumatic diseases
Q53807397Pharmacogenetics: more than skin deep.
Q77814090Pharmacogenomics and the (ir)relevance of race
Q28071448Pharmacogenomics in Pediatric Patients: Towards Personalized Medicine
Q35116109Pharmacogenomics: implications and considerations for pharmacists
Q35090217Pharmacogenomics: marshalling the human genome to individualise drug therapy
Q38124254Pharmacometabonomics and personalized medicine
Q41265929Phenotyping and genotyping of CYP2C19 using comparative metabolism of proguanil in sickle-cell disease patients and healthy controls in Nigeria
Q26999391Placental transfer of antidepressant medications: implications for postnatal adaptation syndrome
Q42151556Prakriti-based medicine: A step towards personalized medicine
Q39642852Privacy issues in personalized medicine.
Q34079045Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
Q39570743Quantitative prediction of tumor response to neoadjuvant chemotherapy in breast cancer: novel marker genes and prediction model using the expression levels
Q33570878Revitalizing personalized medicine: respecting biomolecular complexities beyond gene expression
Q61959358Role of Cytochrome P450 Polymorphisms in the Development of Pulmonary Drug Toxicity
Q36441540Role of pharmacogenomics in the treatment of tuberculosis: a review
Q47450125Role of structural bioinformatics and traditional Chinese medicine databases in pharmacogenomics.
Q48285119SNP databases and pharmacogenetics: great start, but a long way to go.
Q36967772SNPs in disease gene mapping, medicinal drug development and evolution
Q33733501Screening for 392 polymorphisms in 141 pharmacogenes
Q40008844Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis
Q39253575TMEM158 and FBLP1 as novel marker genes of cisplatin sensitivity in non-small cell lung cancer cells
Q40479885Tailor-made pharmacotherapy: future developments and ethical challenges in the field of pharmacogenomics.
Q36996178Testing gene-treatment interactions in pharmacogenetic studies
Q39210061The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine
Q24791186The genome Assembly Archive: a new public resource
Q47342870The interactions of age, sex, body mass index, genetics, and steroid weight-based doses on tacrolimus dosing requirement after adult kidney transplantation
Q36545015The role of drug-metabolising enzymes in clinical responses to chemotherapy
Q34609157The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics
Q34575544Theoretical basis for the identification of allelic variants that encode drug efficacy and toxicity
Q35615776Thymidylate synthase and thymidine phosphorylase gene expression as predictive parameters for the efficacy of 5-fluorouracil-based adjuvant chemotherapy for gastric cancer.
Q43284930UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal).
Q36192684Use of CEPH and non-CEPH lymphoblast cell lines in pharmacogenetic studies
Q38107101Use of pharmacogenetics for predicting cancer prognosis and treatment exposure, response and toxicity
Q35024962Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis?
Q34629500XPD DNA nucleotide excision repair gene polymorphisms associated with DNA repair deficiency predict better treatment outcomes in secondary acute myeloid leukemia
Q58673700[Pharmacogenetics II. Research molecular methods, bioinformatics and ethical concerns]
Q48640226beta2 adrenoceptor (ADRB2) pharmacogenetics and cardiovascular phenotypes during laryngoscopy and tracheal intubation.

Search more.