scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1038/TPJ.2016.78 |
P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/tpj.2016.78 |
P932 | PMC publication ID | 5380847 |
P698 | PubMed publication ID | 27779243 |
P50 | author | Daniel Shriner | Q56456791 |
P2093 | author name string | J L Baker | |
A R Bentley | |||
C N Rotimi | |||
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Twenty years post-NIH Revitalization Act: enhancing minority participation in clinical trials (EMPaCT): laying the groundwork for improving minority clinical trial accrual... | Q27023862 | ||
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Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation | Q28290595 | ||
Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus | Q28291275 | ||
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Pharmacometrics: opportunity for reducing disease burden in the developing world: the case of Africa | Q42249532 | ||
Population genetics of IFIH1: ancient population structure, local selection, and implications for susceptibility to type 1 diabetes | Q43031184 | ||
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. | Q43521980 | ||
Genotype and allele frequency of a 32-base pair deletion mutation in the CCR5 gene in various ethnic groups: absence of mutation among Asians and Pacific Islanders | Q43570037 | ||
G6PD testing in support of treatment and elimination of malaria: recommendations for evaluation of G6PD tests | Q43721671 | ||
Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate | Q43863009 | ||
Natural resistance to HIV? | Q43910982 | ||
Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa | Q43932822 | ||
Distribution of HLA-A, B and DRB1 alleles in Sahariya tribe of North Central India: an association with pulmonary tuberculosis | Q44000756 | ||
Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients | Q44281312 | ||
The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity | Q44391267 | ||
Consistency of genome-wide associations across major ancestral groups | Q44515366 | ||
High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe | Q46526697 | ||
Natural selection and resistance to HIV. | Q46753804 | ||
Absence of APOL1 risk variants protects against HIV-associated nephropathy in the Ethiopian population | Q46897462 | ||
Glucose-6-phosphate dehydrogenase and malaria. Greater resistance of females heterozygous for enzyme deficiency and of males with non-deficient variant | Q46973697 | ||
Increased susceptibility of Fas ligand-deficient gld mice to Trypanosoma cruzi infection due to a Th2-biased host immune response. | Q52908239 | ||
Fas-FasL interaction modulates nitric oxide production in Trypanosoma cruzi-infected mice. | Q52931841 | ||
High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study | Q56829831 | ||
Pharmacogenomics, ancestry and clinical decision making for global populations | Q57278395 | ||
Ethnic Diversity and Its Environmental Determinants: Effects of Climate, Pathogens, and Habitat Diversity | Q57539943 | ||
Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles | Q58003139 | ||
Control and surveillance of African trypanosomiasis. Report of a WHO Expert Committee | Q58842952 | ||
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir | Q34117815 | ||
Sleeping sickness: a tale of two diseases. | Q34118109 | ||
Posttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding. | Q34123911 | ||
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants | Q34125166 | ||
Ancestry and disease in the age of genomic medicine | Q34143193 | ||
Lassa fever, a new virus disease of man from West Africa. I. Clinical description and pathological findings | Q34204840 | ||
Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence | Q34213787 | ||
Mechanism of Trypanosoma brucei gambiense resistance to human serum | Q34365663 | ||
APOL1 risk variants, race, and progression of chronic kidney disease | Q34383679 | ||
Global distribution of the CCR5 gene 32-basepair deletion. | Q34425080 | ||
The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. | Q34456594 | ||
Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception? | Q34644273 | ||
Lassa fever. Effective therapy with ribavirin | Q34694588 | ||
Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic | Q34733732 | ||
A deletion in the chemokine receptor 5 (CCR5) gene is associated with tickborne encephalitis | Q34733739 | ||
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study | Q34756398 | ||
Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population | Q34778035 | ||
Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations | Q34826590 | ||
The African Genome Variation Project shapes medical genetics in Africa | Q34979569 | ||
Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study | Q34998144 | ||
Next generation disparities in human genomics: concerns and remedies | Q35008340 | ||
Genomic and personalized medicine: foundations and applications | Q35014059 | ||
Genetic susceptibility to tuberculosis in Africans: a genome-wide scan | Q35174396 | ||
The SLCO1B1 rs4149032 polymorphism is highly prevalent in South Africans and is associated with reduced rifampin concentrations: dosing implications. | Q35191432 | ||
The clinical role and cost-effectiveness of long-acting antiretroviral therapy | Q35197271 | ||
Genetic variation and pharmacogenomics: concepts, facts, and challenges | Q35236771 | ||
Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences | Q35238375 | ||
Moving toward true inclusion of racial/ethnic minorities in federally funded studies. A key step for achieving respiratory health equality in the United States. | Q35261972 | ||
Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study | Q35426496 | ||
Genetic analysis implicates resistin in HIV lipodystrophy | Q35538933 | ||
Patterns of ethnic diversity among the genes that influence AIDS. | Q35649567 | ||
Updated estimate of the duration of the meningo-encephalitic stage in gambiense human African trypanosomiasis | Q35682276 | ||
Genome-wide scans provide evidence for positive selection of genes implicated in Lassa fever | Q35701103 | ||
Plasmodium vivax Transmission in Africa | Q35847037 | ||
Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled | Q35869663 | ||
Antimalarial drug resistance, artemisinin-based combination therapy, and the contribution of modeling to elucidating policy choices | Q35872678 | ||
Association between human leukocyte antigen class II and pulmonary tuberculosis due to mycobacterium tuberculosis in Uganda | Q35902458 | ||
Distribution of human CYP2C8*2 allele in three different African populations | Q35963368 | ||
Low prevalence of CCR5-Δ32, CCR2-64I and SDF1-3'A alleles in the Baiga and Gond tribes of Central India. | Q35991885 | ||
Human African trypanosomiasis: clinical presentation and immune response | Q36072554 | ||
Effects of CYP2B6 and CYP1A2 Genetic Variation on Nevirapine Plasma Concentration and Pharmacodynamics as Measured by CD4 Cell Count in Zimbabwean HIV-Infected Patients | Q36074119 | ||
APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans | Q36223249 | ||
Evaluation of genome wide association study associated type 2 diabetes susceptibility loci in sub Saharan Africans | Q36309642 | ||
Differential evolution of a CXCR4-using HIV-1 strain in CCR5wt/wt and CCR5∆32/∆32 hosts revealed by longitudinal deep sequencing and phylogenetic reconstruction. | Q36343848 | ||
HLA class II disease associations in southern Africa | Q36379492 | ||
The future of genomic medicine education in Africa | Q28645593 | ||
Where Next for Genetics and Genomics? | Q28645977 | ||
The H3Africa policy framework: negotiating fairness in genomics | Q28648286 | ||
What does genomic medicine mean for diverse populations? | Q28659678 | ||
Ethiopian genetic diversity reveals linguistic stratification and complex influences on the Ethiopian gene pool | Q28729180 | ||
Trends in population-based studies of human genetics in infectious diseases | Q28732216 | ||
Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach | Q28748816 | ||
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping | Q28748891 | ||
The evolution of human genetic and phenotypic variation in Africa | Q28749146 | ||
Estimates of the duration of the early and late stage of gambiense sleeping sickness | Q28755434 | ||
Worldwide human relationships inferred from genome-wide patterns of variation | Q29547228 | ||
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance | Q29614684 | ||
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene | Q29614892 | ||
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy | Q29614896 | ||
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection | Q29614956 | ||
The neglected burden of Plasmodium vivax malaria | Q29618450 | ||
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C | Q29619541 | ||
Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons. | Q30350498 | ||
Global epidemiology of HIV. | Q30353968 | ||
Risk maps of Lassa fever in West Africa | Q33414102 | ||
Association of HLA-A, -B, and -DRB1 with pulmonary tuberculosis in western Javanese Indonesia | Q33571165 | ||
Evolution of the primate trypanolytic factor APOL1 | Q33665446 | ||
Trypanosomiasis-induced Th17-like immune responses in carp. | Q33707467 | ||
Genetic variants associated with complex human diseases show wide variation across multiple populations | Q33714507 | ||
Bayesian geostatistical analysis and prediction of Rhodesian human African trypanosomiasis | Q33784178 | ||
The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000-2009: the way forward | Q33834072 | ||
Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes | Q33876727 | ||
Enzymatic deficiency in primaquine-sensitive erythrocytes | Q33969317 | ||
Pharmacogenetics of antimalarial drugs: effect on metabolism and transport | Q34020238 | ||
Can pharmacogenomics improve malaria drug policy? | Q34029396 | ||
Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases | Q34031536 | ||
Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry | Q34038606 | ||
Duration of symptoms and case fatality of sleeping sickness caused by Trypanosoma brucei rhodesiense in Tororo, Uganda | Q34066335 | ||
Research capacity. Enabling the genomic revolution in Africa | Q34068017 | ||
Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution | Q34071411 | ||
Genetic perspectives on human origins and differentiation | Q34101048 | ||
PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients | Q36468872 | ||
APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults | Q36520457 | ||
Human leukocyte antigens and susceptibility to tuberculosis: a meta-analysis of case-control studies. | Q36539390 | ||
Antituberculosis drugs and hepatotoxicity | Q36628708 | ||
Duffy blood group and malaria | Q36868609 | ||
Drug-resistant malaria - an insight | Q36933785 | ||
Challenges in human genetic diversity: demographic history and adaptation | Q36958118 | ||
Antituberculosis drug-induced hepatotoxicity: concise up-to-date review | Q36998032 | ||
Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations. | Q37010357 | ||
Imported lassa fever in Germany: molecular characterization of a new lassa virus strain | Q37064973 | ||
Widespread balancing selection and pathogen-driven selection at blood group antigen genes | Q37119639 | ||
Artemisinin-based combination therapy for uncomplicated malaria in sub-Saharan Africa: the efficacy, safety, resistance and policy implementation since Abuja 2000. | Q37171336 | ||
Application of pharmacogenomics to malaria: a holistic approach for successful chemotherapy | Q37278622 | ||
Successful translation of pharmacogenetics into the clinic: the abacavir example | Q37436365 | ||
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans | Q37471061 | ||
Individualized genomics and the future of translational medicine | Q37483876 | ||
Severity of human african trypanosomiasis in East Africa is associated with geographic location, parasite genotype, and host inflammatory cytokine response profile | Q37624109 | ||
The next-generation sequencing revolution and its impact on genomics | Q37672566 | ||
Genomic medicine in Africa: promise, problems and prospects | Q37690919 | ||
Increased burden of cardiovascular disease in carriers of APOL1 genetic variants | Q37696155 | ||
End-stage renal disease in African Americans with lupus nephritis is associated with APOL1 | Q37728822 | ||
NAT2 polymorphisms and susceptibility to anti-tuberculosis drug-induced liver injury: a meta-analysis | Q37992742 | ||
G6PD deficiency: global distribution, genetic variants and primaquine therapy | Q38079323 | ||
Next-generation sequencing platforms | Q38096497 | ||
African variation at Cytochrome P450 genes: Evolutionary aspects and the implications for the treatment of infectious diseases. | Q38183664 | ||
Cytochrome P450 pharmacogenetics in African populations: implications for public health | Q38192688 | ||
The molecular arms race between African trypanosomes and humans | Q38224214 | ||
Provision of antiretroviral therapy in South Africa: the nuts and bolts | Q38259626 | ||
A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome | Q38345868 | ||
Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses, and drug-drug interactions. | Q38622785 | ||
Beyond Tsetse--Implications for Research and Control of Human African Trypanosomiasis Epidemics | Q38716735 | ||
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy | Q38870064 | ||
Comparison of sulfadoxine-pyrimethamine, unsupervised artemether-lumefantrine, and unsupervised artesunate-amodiaquine fixed-dose formulation for uncomplicated plasmodium falciparum malaria in Benin: a randomized effectiveness noninferiority trial | Q39000745 | ||
The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression | Q39249450 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International | Q24082749 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | infection | Q166231 |
genetics | Q7162 | ||
genetic variation | Q349856 | ||
molecular evolution | Q856529 | ||
infectious disease | Q18123741 | ||
pharmacogenomics | Q1152227 | ||
pharmacogenetics | Q1358521 | ||
pharmacogenomic variants | Q71227267 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 112-120 | |
P577 | publication date | 2016-10-25 | |
2017-03-01 | |||
P1433 | published in | The Pharmacogenomics Journal | Q10534704 |
P1476 | title | Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa | |
P478 | volume | 17 |
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