Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver

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Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1085111960
P356DOI10.1038/S41598-017-01526-5
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/s41598-017-01526-5
P932PMC publication ID5430975
P698PubMed publication ID28465592

P50authorChristian MalteccaQ82642850
P2093author name stringJames D Brooks
James L Yeatts
Jeremy T Howard
Melissa S Ashwell
Ronald E Baynes
P2860cites workUrsodeoxycholic acid enhances the absorption of cyclosporine in a heart transplant patient with short bowel syndromeQ67966507
Biliary secretion and enterohepatic recycling of fenbendazole metabolites in sheepQ72866890
Pharmacokinetics of fenbendazole following intravenous and oral administration to pigsQ73769515
Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levelsQ79840749
Transcript length bias in RNA-seq data confounds systems biologyQ21093194
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Analyses of pig genomes provide insight into porcine demography and evolutionQ22122156
Gene ontology: tool for the unification of biologyQ23781406
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A review of antibiotic use in food animals: perspective, policy, and potentialQ24630387
Differential Gene Expression across Breed and Sex in Commercial Pigs Administered Fenbendazole and Flunixin MeglumineQ27318232
edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataQ27860819
Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine modelQ28248944
Cytochrome P450s and cholesterol homeostasisQ28254484
Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discoveryQ28261086
Effect of bile acids on absorption of nitrendipine in healthy subjectsQ28365945
The genetic architecture of the genome-wide transcriptional response to ER stress in the mouseQ28546777
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A general framework for weighted gene co-expression network analysisQ29617580
limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
Hierarchical organization of modularity in metabolic networksQ29618451
BioMart and Bioconductor: a powerful link between biological databases and microarray data analysisQ30998448
Data supporting ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretionQ31033407
Possible mechanisms underlying the testicular toxicity of oxfendazole in rats.Q31034963
A powerful and flexible linear mixed model framework for the analysis of relative quantification RT-PCR dataQ33440981
Gene co-expression network analysis identifies porcine genes associated with variation in Salmonella sheddingQ33805188
The effect of food and bile acid administration on the relative bioavailability of cyclosporinQ34398429
Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R.Q34714933
Pharmacokinetics of flunixin meglumine in mature swine after intravenous, intramuscular and oral administration.Q34938796
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Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRtQ35174434
Pharmacokinetics and pharmacodynamic effects of flunixin after intravenous, intramuscular and oral administration to dairy goatsQ35695579
Coordinate transcriptional regulation of bile acid homeostasis and drug metabolismQ35974423
Impairment of the ubiquitin-proteasome pathway by methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate leads to a potent cytotoxic effect in tumor cells: a novel antiproliferative agent with a potential therapeutic implicationQ36216436
Biologic effects of fenbendazole in rats and mice: a review.Q36997850
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UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the dimer-dimer subunit interfacesQ37368613
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Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variationQ38075335
The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cellsQ38330500
Health concerns and management of select veterinary drug residuesQ38691975
The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swineQ39210061
Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosisQ40558204
Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasisQ43737827
Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitisQ44876859
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesWGCNAQ102537983
limmaQ112236343
edgeRQ113334690
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)1357
P577publication date2017-05-02
P1433published inScientific ReportsQ2261792
P1476titleGene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver
P478volume7

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cites work (P2860)
Q50305648Genetic Parameter Estimates for Metabolizing Two Common Pharmaceuticals in Swine.
Q98735812Muscle Transcriptome Analysis Reveals Potential Candidate Genes and Pathways Affecting Intramuscular Fat Content in Pigs
Q52721786The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone.

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