The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse

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The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1004924
P3181OpenCitations bibliographic resource ID846353
P932PMC publication ID4412289
P698PubMed publication ID25651210
P5875ResearchGate publication ID272074721

P50authorAndrew G. ClarkQ4757042
Mariana WolfnerQ57317305
P2093author name stringXu Wang
Clement Y Chow
David Riccardi
P2860cites workIdentification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factorsQ22008465
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein responseQ24548363
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationQ24627354
Sestrins at the crossroad between stress and agingQ24633564
TopHat: discovering splice junctions with RNA-SeqQ24655505
The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stressQ24655508
oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genesQ24810241
The noncoding RNA revolution-trashing old rules to forge new onesQ26851952
Micro(RNA)managing endoplasmic reticulum stressQ27001727
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing dataQ27860742
edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataQ27860819
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene listsQ28131785
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein responseQ28139950
Intracellular signaling by the unfolded protein responseQ28250477
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems geneticsQ37349416
Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences.Q37352508
Stress-induced changes in gene interactions in human cellsQ37574224
Genetic and haplotype diversity among wild-derived mouse inbred strains.Q37593047
An enhanced integrated stress response ameliorates mutant SOD1-induced ALS.Q37708372
The collaborative cross: a recombinant inbred mouse population for the systems genetic era.Q37853776
Dimer-specific regulatory mechanisms within the NF-κB family of transcription factorsQ37995686
Endoplasmic reticulum stress signaling: the microRNA connectionQ38091632
The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complexQ39727479
Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of Akt.Q42483656
CACTIN is an essential nuclear protein in Arabidopsis and may be associated with the eukaryotic spliceosomeQ45347510
Female x male interactions in Drosophila sperm competition.Q50849240
Regulatory changes underlying expression differences within and between Drosophila species.Q52688606
The eukaryotic initiation factor-2 kinase pathway facilitates differential GADD45a expression in response to environmental stress.Q53582779
The Collaborative Cross, a community resource for the genetic analysis of complex traitsQ56896214
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-IIQ81144490
The unfolded protein response and cellular stress, Part A.. PrefaceQ83296006
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetesQ28506402
Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethalityQ28587457
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survivalQ28593963
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein responseQ28611502
Trimmomatic: a flexible trimmer for Illumina sequence dataQ29547278
Cytoscape 2.8: new features for data integration and network visualizationQ29547471
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3Q29614852
Common regulatory variation impacts gene expression in a cell type-dependent mannerQ29614882
Mouse genomic variation and its effect on phenotypes and gene regulationQ29617750
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteinsQ33262919
Moderated statistical tests for assessing differences in tag abundanceQ33299648
Transcriptome-wide identification of novel imprinted genes in neonatal mouse brainQ33389173
Methods for monitoring endoplasmic reticulum stress and the unfolded protein response.Q33652280
UPR-inducible miRNAs contribute to stressful situationsQ33752232
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expressionQ33783132
The architecture of gene regulatory variation across multiple human tissues: the MuTHER studyQ33815387
Gene expression and genetic variation in response to endoplasmic reticulum stress in human cellsQ33847195
Regulatory divergence in Drosophila revealed by mRNA-seq.Q33881371
Using next-generation RNA sequencing to identify imprinted genes.Q33927875
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signalingQ34179244
RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations.Q34243017
The genetic basis for male x female interactions underlying variation in reproductive phenotypes of DrosophilaQ34386972
ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.Q34460275
The unfolded protein response in familial amyotrophic lateral sclerosisQ34549529
Genetic analysis of complex traits in the emerging Collaborative CrossQ35145475
High-resolution genetic mapping using the Mouse Diversity outbred populationQ35748248
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variationQ36044823
The impact of the unfolded protein response on human diseaseQ36062081
Sequence-based characterization of structural variation in the mouse genomeQ36193488
Extensive compensatory cis-trans regulation in the evolution of mouse gene expressionQ36446194
The Diversity Outbred mouse population.Q36474146
Identification of steroid-sensitive gene-1/Ccdc80 as a JAK2-binding protein.Q36714862
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetesQ36861224
Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genesQ36895564
Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkageQ37269736
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
edgeRQ113334690
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)e1004924
P577publication date2015-02-01
P1433published inPLOS GeneticsQ1893441
P1476titleThe genetic architecture of the genome-wide transcriptional response to ER stress in the mouse
P478volume11

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cites work (P2860)
Q58799768Baldspot/ELOVL6 is a conserved modifier of disease and the ER stress response
Q52840228Bringing genetic background into focus.
Q37057427Cryptic Genetic Variation in Evolutionary Developmental Genetics
Q89664044Decoupling of Apoptosis from Activation of the ER Stress Response by the Drosophila Metallopeptidase superdeath
Q38653861ER stress and the unfolded protein response in neurodegeneration
Q42350805Erratum: Proteostasis control by the unfolded protein response
Q33683604Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver
Q93162268High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation
Q54116854IreA controls endoplasmic reticulum stress-induced autophagy and survival through homeostasis recovery.
Q46579757Omega-3 fatty acids increase the unfolded protein response and improve amyloid-β phagocytosis by macrophages of patients with mild cognitive impairment
Q38540196Proteostasis control by the unfolded protein response
Q42368371The Alterations in Mitochondrial DNA Copy Number and Nuclear-Encoded Mitochondrial Genes in Rat Brain Structures after Cocaine Self-Administration

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