scholarly article | Q13442814 |
P356 | DOI | 10.1023/A:1012244520615 |
P698 | PubMed publication ID | 11697464 |
P50 | author | Tsutomu Nakamura | Q57023886 |
P2093 | author name string | K Okumura | |
M Hirai | |||
M Kasuga | |||
T Tamura | |||
T Sakai | |||
M Kakumoto | |||
Y Morita | |||
N Aoyama | |||
T Sakaeda | |||
M Horinouchi | |||
N Ohmoto | |||
P2860 | cites work | Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues | Q24633406 |
Recent progress in P-glycoprotein research. | Q33686903 | ||
Multidrug resistance in human tumors--molecular diagnosis and clinical significance | Q33720478 | ||
Role of P-glycoprotein in drug disposition | Q33845762 | ||
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs | Q34059522 | ||
The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation. | Q34162850 | ||
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants | Q34488592 | ||
Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine | Q34620070 | ||
Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo | Q35113118 | ||
Clinical pharmacokinetic significance of the renal tubular secretion of digoxin | Q39684941 | ||
Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated Nal and SDS. | Q40399731 | ||
Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals | Q40624014 | ||
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin | Q40851439 | ||
Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone | Q41590183 | ||
Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). | Q41596609 | ||
Isolation of DNA from biological specimens without extraction with phenol | Q70044147 | ||
Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum) | Q73145709 | ||
The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs | Q77182829 | ||
P433 | issue | 10 | |
P921 | main subject | pharmacokinetics | Q323936 |
P304 | page(s) | 1400-1404 | |
P577 | publication date | 2001-10-01 | |
P1433 | published in | Pharmaceutical Research | Q7180737 |
P1476 | title | MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects | |
P478 | volume | 18 |
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