scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1001679241 |
P356 | DOI | 10.1007/BF03256456 |
P2888 | exact match | https://scigraph.springernature.com/pub.10.1007/bf03256456 |
P698 | PubMed publication ID | 16771603 |
P50 | author | Jos Beijnen | Q23771643 |
P2093 | author name string | J H M Schellens | |
I Meijerman | |||
P H M Smits | |||
V D Doodeman | |||
T M Bosch | |||
P2860 | cites work | Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome | Q24540140 |
UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer | Q24648015 | ||
Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? | Q24670527 | ||
Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects | Q28206464 | ||
Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome | Q28209501 | ||
Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome | Q28258556 | ||
Rapid and simple method for purification of nucleic acids | Q29615124 | ||
Genetic variability in CYP3A5 and its possible consequences. | Q30341330 | ||
Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28. | Q31043181 | ||
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data. | Q32072529 | ||
Multidrug resistance-associated protein subfamily transporters and drug resistance | Q33686909 | ||
A systematic review of genetic polymorphisms and breast cancer risk. | Q33766628 | ||
Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. | Q33833585 | ||
ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2. | Q33938893 | ||
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. | Q34130450 | ||
Genotyping of cytochrome P450 2D6*3 and *4 mutations using conventional PCR. | Q34285997 | ||
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism | Q34735686 | ||
Genetic polymorphisms of the human MDR1 drug transporter | Q34931160 | ||
Pharmacogenetics of the major polymorphic metabolizing enzymes. | Q35067187 | ||
Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo | Q35113118 | ||
Variations of the bilirubin uridine-diphosphoglucuronosyl transferase 1A1 gene in healthy Taiwanese | Q74278947 | ||
Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms | Q74462951 | ||
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations | Q74598011 | ||
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects | Q77133730 | ||
CYP3A5 variant allele frequencies in Dutch Caucasians | Q77221613 | ||
Mutation analysis of the human CYP3A4 gene 5' regulatory region: population screening using non-radioactive SSCP | Q77758106 | ||
Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism | Q77788818 | ||
UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations | Q78201971 | ||
Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil | Q35749424 | ||
Relationship between proguanil metabolic ratio and CYP2C19 genotype in a Caucasian population | Q35802629 | ||
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males | Q35804210 | ||
Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population. | Q36054252 | ||
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity | Q38315596 | ||
Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan | Q38347530 | ||
Homozygous mutation Arg768Trp in the ABC-transporter encoding gene MRP2/cMOAT/ABCC2 causes Dubin-Johnson syndrome in a Caucasian patient | Q38351098 | ||
Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype. | Q38457450 | ||
Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population. | Q40506352 | ||
Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency. | Q43606229 | ||
No influence of the MDR-1 C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin A trough concentrations or rejection incidence in stable renal transplant recipients | Q43618856 | ||
Identification and functional characterization of eight CYP3A4 protein variants | Q43686375 | ||
Frequency of C3435T polymorphism of MDR1 gene in African people | Q43705274 | ||
Identification of functionally variant MDR1 alleles among European Americans and African Americans | Q43705904 | ||
Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer | Q43743146 | ||
Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. | Q43803779 | ||
CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity | Q43926477 | ||
I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma | Q43993684 | ||
Analysis of GSTP1-1 polymorphism using real-time polymerase chain reaction | Q44317905 | ||
Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups | Q44534413 | ||
CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation | Q44872808 | ||
An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children | Q45305768 | ||
Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations | Q46141212 | ||
Characterization of an allelic variant in the nifedipine-specific element of CYP3A4: ethnic distribution and implications for prostate cancer risk. Mutations in brief no. 191. Online | Q46164950 | ||
A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination | Q46466430 | ||
Genomic evidence for recent positive selection at the human MDR1 gene locus | Q46509410 | ||
Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population | Q46681441 | ||
Metabolic gene polymorphism frequencies in control populations | Q46857953 | ||
Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population. | Q47296992 | ||
Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter polymorphisms among distinct ethnic groups from Brazil | Q47582860 | ||
Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population. | Q47738894 | ||
Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease | Q48320745 | ||
Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease. | Q48476423 | ||
A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. | Q50995791 | ||
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. | Q52965959 | ||
Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic leukemia. | Q54701330 | ||
Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population. | Q64923947 | ||
Genetic tests which identify the principal defects in CYP2C19 responsible for the polymorphism in mephenytoin metabolism | Q71497765 | ||
Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4 | Q73052606 | ||
CYP3A4-V polymorphism detection by PCR-restriction fragment length polymorphism analysis and its allelic frequency among 199 Dutch Caucasians | Q73162883 | ||
Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world | Q73257076 | ||
Influence of GSTM1, GSTT1, GSTP1, and EPHX gene polymorphisms on DNA adduct level and HPRT mutant frequency in coke-oven workers | Q73355668 | ||
Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene | Q73393155 | ||
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene | Q73740950 | ||
Known variant DPYD alleles do not explain DPD deficiency in cancer patients | Q73769582 | ||
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells | Q74127572 | ||
P433 | issue | 3 | |
P304 | page(s) | 175-185 | |
P577 | publication date | 2006-01-01 | |
P1433 | published in | Molecular Diagnosis and Therapy | Q15758832 |
P1476 | title | Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population | |
P478 | volume | 10 |
Q35062331 | ABCB1 genotypes and haplotypes in patients with dementia and age-matched non-demented control patients |
Q50758475 | An iterative searching and ranking algorithm for prioritising pharmacogenomics genes. |
Q37345974 | Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review |
Q30939373 | Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population |
Q37818297 | Finasteride metabolism and pharmacogenetics: new approaches to personalized prevention of prostate cancer. |
Q33632608 | Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans? |
Q80068795 | Rapid detection of the DPYD IVS14+1G>A mutation for screening patients to prevent fluorouracil-related toxicity |
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