Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms.

scientific article published in July 2017

Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TRANSPROCEED.2017.03.093
P698PubMed publication ID28736028

P50authorYuta OhnoQ84515177
P2093author name stringA Suzuki
T Tsuchiya
Y Itoh
T Deguchi
M Fujitani
K Horie
M Soda
K Kanamori
K Kitaichi
S Yoshikuni
A Shibayama
R Michiuchi
P2860cites workImpact of the CYP3A5, CYP3A4, COMT, IL-10 and POR genetic polymorphisms on tacrolimus metabolism in Chinese renal transplant recipientsQ28538933
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Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conferenceQ37379749
Clinical pharmacokinetics of tacrolimusQ41096852
MDR1 genotypes do not influence the absorption of a single oral dose of 600 mg valacyclovir in healthy Chinese Han ethnic malesQ41324351
Frequencies and roles of CYP3A5, CYP3A4 and ABCB1 single nucleotide polymorphisms in Italian teenagers after kidney transplantation.Q42754368
Effect of different tacrolimus levels on early outcomes after kidney transplantationQ43901985
Influence of cytochrome P450 (CYP) 3A4*1G polymorphism on the pharmacokinetics of tacrolimus, probability of acute cellular rejection, and mRNA expression level of CYP3A5 rather than CYP3A4 in living-donor liver transplant patientsQ44066270
Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipientsQ44486217
Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimusQ44579589
Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.Q44632277
The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.Q44899003
The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patientsQ44914011
CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantationQ44958936
Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipientsQ45122563
Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South AsiansQ45281322
Trough tacrolimus concentrations in the first week after kidney transplantation are related to acute rejection.Q45983572
Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipientsQ46512720
Influence of CYP3A5, ABCB1 and NR1I2 polymorphisms on prednisolone pharmacokinetics in renal transplant recipientsQ46576181
Influence of CYP3A5 and MDR1 polymorphisms on tacrolimus concentration in the early stage after renal transplantationQ46690564
A pharmacogenetic strategy for immunosuppression based on the CYP3A5 genotype.Q46796371
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expressionQ46906576
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.Q52965959
CYP3A and ABCB1 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of tacrolimus and its metabolites (M-I and M-III).Q53122247
Relationship of FK506 whole blood concentrations and efficacy and toxicity after liver and kidney transplantationQ71700445
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjectsQ77133730
CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipientsQ79456645
Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirementsQ80252228
CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipientsQ80316046
Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantationQ83522225
Impact of the CYP3A4*1G polymorphism and its combination with CYP3A5 genotypes on tacrolimus pharmacokinetics in renal transplant patientsQ84255299
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmultiple drug resistanceQ643839
P304page(s)1492-1498
P577publication date2017-07-01
P1433published inTransplantation ProceedingsQ7834825
P1476titleAssociation Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms
P478volume49

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