| scholarly article | Q13442814 |
| P50 | author | Klaus Okkenhaug | Q38546924 |
| Robert G Hawley | Q40101931 | ||
| Robert Rottapel | Q51814787 | ||
| P2093 | author name string | Dubreuil P | |
| Rose JL | |||
| De Sepulveda P | |||
| P2860 | cites work | Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis | Q24293012 |
| vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells | Q24296261 | ||
| A family of cytokine-inducible inhibitors of signalling | Q24313168 | ||
| A new protein containing an SH2 domain that inhibits JAK kinases | Q24313242 | ||
| p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells | Q24315152 | ||
| Twenty proteins containing a C-terminal SOCS box form five structural classes | Q24317684 | ||
| Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1 | Q24320046 | ||
| Cloning and characterization of novel CIS family genes | Q24321480 | ||
| Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system | Q24324127 | ||
| Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3 | Q24324173 | ||
| Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism | Q24337545 | ||
| SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain | Q24533530 | ||
| Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding | Q24607293 | ||
| The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors | Q27860467 | ||
| A novel genetic system to detect protein-protein interactions | Q27860915 | ||
| The small GTP-binding protein rac regulates growth factor-induced membrane ruffling | Q27861063 | ||
| Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells | Q28114982 | ||
| Modulation of Kit/stem cell factor receptor-induced signaling by protein kinase C | Q28118872 | ||
| Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells | Q28186886 | ||
| Stem cell factor and hematopoiesis | Q28247104 | ||
| SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase | Q28252144 | ||
| Jak2 is essential for signaling through a variety of cytokine receptors | Q28270987 | ||
| p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity | Q28280824 | ||
| Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2 | Q28285431 | ||
| Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors | Q28287188 | ||
| Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division | Q28288340 | ||
| Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis | Q28295920 | ||
| Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the murine Flt3 receptor tyrosine kinase | Q28507072 | ||
| Biochemical characterization and analysis of the transforming potential of the FLT3/FLK2 receptor tyrosine kinase | Q28508564 | ||
| The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1 | Q28511655 | ||
| Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs | Q28565211 | ||
| Structure and function of a new STAT-induced STAT inhibitor | Q28584775 | ||
| Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture | Q28594956 | ||
| JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor | Q28637652 | ||
| C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains | Q29618334 | ||
| Structural basis for the binding of proline-rich peptides to SH3 domains | Q29620408 | ||
| Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav. | Q30176877 | ||
| Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2. | Q30177046 | ||
| Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes | Q30193572 | ||
| Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. | Q30193575 | ||
| Cloning of a Grb2 isoform with apoptotic properties | Q30194342 | ||
| CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line | Q30454003 | ||
| Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signaling | Q33887555 | ||
| Does Vav bind to F‐actin through a CH domain? | Q34297863 | ||
| A specific combination of substrates is involved in signal transduction by the kit-encoded receptor. | Q35922486 | ||
| c-kit ligand: a unique potentiator of mediator release by human lung mast cells | Q36230802 | ||
| The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor. | Q36695763 | ||
| Ras-Raf interaction: two-hybrid analysis | Q36786557 | ||
| Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo | Q36812664 | ||
| Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation | Q36843943 | ||
| c-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling | Q37386114 | ||
| Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development | Q37570452 | ||
| Deletion of the c-kit protooncogene in the human developmental defect piebald trait | Q37637333 | ||
| Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells. | Q37693932 | ||
| Receptor functions and ligand-dependent transforming potential of a chimeric kit proto-oncogene | Q38338589 | ||
| Hereditary anemias of the mouse: a review for geneticists | Q39838682 | ||
| Activation of phosphatidylinositol 3-kinase is necessary for differentiation of FDC-P1 cells following stimulation of type III receptor tyrosine kinases | Q41051459 | ||
| A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells | Q41066600 | ||
| Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene | Q41358116 | ||
| Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development | Q41414243 | ||
| Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. | Q41489527 | ||
| Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors | Q41528217 | ||
| Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates | Q41635684 | ||
| The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7 | Q41682559 | ||
| c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities | Q41695888 | ||
| Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors | Q42805800 | ||
| Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes | Q42810922 | ||
| Transformation of NIH3T3 fibroblasts by the c-Kit receptor tyrosine kinase: effect of receptor density and ligand-requirement | Q42832485 | ||
| Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages. | Q44750262 | ||
| Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction | Q46517603 | ||
| Stem cell factor in combination with granulocyte colony-stimulating factor (CSF) or granulocyte-macrophage CSF synergistically increases granulopoiesis in vivo | Q46643758 | ||
| Identification of residues in GTPase-activating protein Src homology 2 domains that control binding to tyrosine phosphorylated growth factor receptors and p62. | Q52229246 | ||
| W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor | Q52242244 | ||
| Ex vivo expansion with stem cell factor and interleukin-11 augments both short-term recovery posttransplant and the ability to serially transplant marrow | Q57130915 | ||
| Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor | Q57185397 | ||
| Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7 | Q57986982 | ||
| Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule | Q67700733 | ||
| The c-kit receptor ligand functions as a mast cell chemoattractant | Q67895085 | ||
| Effects of human stem cell factor (c-kit ligand) on proliferation of myeloid leukemia cells: heterogeneity in response and synergy with other hematopoietic growth factors | Q67899070 | ||
| Stem cell factor enhances the survival but not the self-renewal of murine hematopoietic long-term repopulating cells | Q71632296 | ||
| Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor | Q72088953 | ||
| Interleukin-12 synergizes with interleukin-3 and steel factor to enhance recovery of murine hemopoietic stem cells in liquid culture | Q72094970 | ||
| Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor | Q72121269 | ||
| Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo | Q73063909 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | steel | Q11427 |
| P304 | page(s) | 904-915 | |
| P577 | publication date | 1999-02-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation | |
| P478 | volume | 18 |
| Q35064718 | A new role for SOCS in insulin action. Suppressor of cytokine signaling |
| Q36109695 | A novel viral SOCS from infectious spleen and kidney necrosis virus: interacts with Jak1 and inhibits IFN-α induced Stat1/3 activation |
| Q87374651 | AS252424, a PI3Kγ inhibitor, downregulates inflammatory responsiveness in mouse bone marrow-derived mast cells |
| Q39747934 | Can SOCS make arthritis better? |
| Q38380126 | Cell regulation by phosphotyrosine-targeted ubiquitin ligases |
| Q37597696 | Chapter 3: Role of SOCS in allergic and innate immune responses |
| Q36360695 | Cross-regulation of JAK and Src kinases |
| Q24672124 | Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development |
| Q43534834 | Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice |
| Q36675716 | Differential regulation of SOCS genes in normal and transformed erythroid cells |
| Q33855769 | Early events in M-CSF receptor signaling |
| Q75266102 | Expression of the c-kit receptor characterizes a subset of neuroblastomas with favorable prognosis |
| Q62675334 | Failure of sensory neurons to express class I MHC is due to differential SOCS1 expression |
| Q33291671 | Favorable prognostic value of SOCS2 and IGF-I in breast cancer |
| Q36923849 | IL-10-Induced miR-155 Targets SOCS1 To Enhance IgE-Mediated Mast Cell Function |
| Q97519166 | Identification of a Human SOCS1 Polymorphism That Predicts Rheumatoid Arthritis Severity |
| Q24551173 | Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain |
| Q28581615 | Insulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cells |
| Q38305477 | Integrative signaling by minimal erythropoietin receptor forms and c-Kit |
| Q53603763 | Interferon gamma has dual potential in inhibiting or promoting survival and growth of hematopoietic progenitors: interactions with stromal cell-derived factor 1. |
| Q35829699 | Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis |
| Q33979008 | Kit signal transduction |
| Q40762466 | Kit signaling and negative regulation of daunorubicin-induced apoptosis: role of phospholipase Cgamma |
| Q92714817 | MicroRNA-142-5p facilitates the pathogenesis of ulcerative colitis by regulating SOCS1 |
| Q38471795 | Modulation of Rho guanine exchange factor Lfc activity by protein kinase A-mediated phosphorylation |
| Q35056767 | Molecular mechanisms utilized by alternative c-kit gene products in the control of spermatogonial proliferation and sperm-mediated egg activation |
| Q35089361 | Negative receptor signalling |
| Q36097785 | Negative regulation of FAK signaling by SOCS proteins |
| Q36231107 | Negative regulation of cytokine and TLR signalings by SOCS and others |
| Q34170858 | Negative regulation of cytokine signaling by the SOCS proteins |
| Q34825460 | Negative regulation of mast cell proliferation by FcgammaRIIB. |
| Q32062430 | Negative regulation of receptor tyrosine kinase signals |
| Q36649111 | Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network |
| Q33894724 | Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1). |
| Q34467795 | Positive versus negative signaling of LET-23: regulation through the adaptor protein, SEM-5. |
| Q38904799 | Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma |
| Q35630518 | Regulation of TLR signaling and inflammation by SOCS family proteins |
| Q35096707 | Regulation of cytokine receptor signaling by SOCS1. |
| Q24554307 | Regulatory and signaling properties of the Vav family |
| Q37076755 | Retinal Axon Guidance Requires Integration of Eya and the Jak/Stat Pathway into Phosphotyrosine-Based Signaling Circuitries in Drosophila |
| Q28143903 | Role of c-kit in mammalian spermatogenesis |
| Q38202542 | SOCS proteins in regulation of receptor tyrosine kinase signaling |
| Q78518680 | SOCS-1 participates in negative regulation of LPS responses |
| Q52174469 | SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. |
| Q36423499 | SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag. |
| Q36984836 | SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients |
| Q50125557 | SOCS1: Regulator of T Cells in Autoimmunity and Cancer. |
| Q41543057 | SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms. |
| Q42456739 | SOCS2 induces neurite outgrowth by regulation of epidermal growth factor receptor activation |
| Q43135527 | SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. |
| Q40720195 | SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc |
| Q38244705 | SOCS6 is a selective suppressor of receptor tyrosine kinase signaling |
| Q62819486 | STAT5b mediates the GH-induced expression of SOCS-2 and SOCS-3 mRNA in the liver |
| Q24675835 | Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation |
| Q28202019 | Signal transduction-associated and cell activation-linked antigens expressed in human mast cells |
| Q33861766 | Signaling mechanisms of cytokine receptors and their perturbances in disease. |
| Q58617998 | Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells |
| Q36382616 | Stem cell factor expression, mast cells and inflammation in asthma |
| Q28585800 | Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling |
| Q28211775 | Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal |
| Q44548846 | Suppressor of cytokine signaling 1 regulates an endogenous inhibitor of a mast cell protease |
| Q39172495 | Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling |
| Q39284759 | Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3. |
| Q28237281 | Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling |
| Q42243167 | Suppressor of cytokine signalling 1 in lymphocytes regulates the development of intestinal inflammation in mice |
| Q40522793 | Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines |
| Q34279168 | Suppressors of cytokine signaling and immunity |
| Q28187852 | Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance |
| Q34716329 | Suppressors of cytokine signalling (SOCS) in the immune system |
| Q38309877 | The C-terminus of CIS defines its interaction pattern |
| Q24321847 | The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins |
| Q28139281 | The F-box: a new motif for ubiquitin dependent proteolysis in cell cycle regulation and signal transduction |
| Q28205975 | The SOCS box: a tale of destruction and degradation |
| Q73370264 | The SOCS-1 story |
| Q40810938 | The TEL-Jak2 oncoprotein induces Socs1 expression and altered cytokine response in Ba/F3 cells |
| Q27026783 | The role of suppressors of cytokine signalling in human neoplasms |
| Q34057877 | The suppressors of cytokine signaling (SOCS) proteins: important feedback inhibitors of cytokine action. |
| Q44039019 | The tumor suppressor activity of SOCS-1. |
| Q34467090 | Thrombopoietin: a pan-hematopoietic cytokine |
| Q34658532 | Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease |
| Q40642728 | Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation |
| Q28186689 | Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras |
| Q36182969 | VHL: a very hip ligase |
| Q28144320 | Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation |
| Q24515205 | Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation |
| Q34870182 | Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. |
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