| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Akihiko Yoshimura | |
| Toshikatsu Hanada | |||
| Masato Kubo | |||
| P2860 | cites work | A family of cytokine-inducible inhibitors of signalling | Q24313168 |
| A new protein containing an SH2 domain that inhibits JAK kinases | Q24313242 | ||
| Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation | Q24533574 | ||
| The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop | Q24533774 | ||
| SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation | Q24537559 | ||
| Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation | Q24538645 | ||
| Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3 | Q24555816 | ||
| The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation | Q24654107 | ||
| Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation | Q24675835 | ||
| SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms | Q28139486 | ||
| CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2 | Q28140132 | ||
| SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985 | Q28140351 | ||
| Gigantism in mice lacking suppressor of cytokine signalling-2 | Q28140549 | ||
| JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling | Q28141157 | ||
| SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality | Q28144528 | ||
| Negative regulation of cytokine signaling pathways | Q28145643 | ||
| Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b) | Q28201918 | ||
| SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130 | Q28211408 | ||
| Cutting edge: Suppressor of cytokine signaling 3 inhibits activation of NFATp | Q28215578 | ||
| A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor | Q28218885 | ||
| Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis | Q28366650 | ||
| SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo | Q28511490 | ||
| Structure and function of a new STAT-induced STAT inhibitor | Q28584775 | ||
| The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo | Q28588059 | ||
| SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities | Q31096727 | ||
| Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice | Q31949951 | ||
| Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation | Q33559005 | ||
| Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1). | Q33894724 | ||
| SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation | Q33958723 | ||
| Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice | Q33959559 | ||
| CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor | Q34116317 | ||
| Cytokine signaling in 2002: new surprises in the Jak/Stat pathway | Q34126053 | ||
| Suppressors of cytokine signalling (SOCS) in the immune system | Q34716329 | ||
| Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation | Q34967884 | ||
| Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease | Q35010293 | ||
| Ingested type I interferon: a potential treatment for autoimmunity | Q35064479 | ||
| The lethal effects of transplantation of Socs1-/- bone marrow cells into irradiated adult syngeneic recipients | Q35168328 | ||
| The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families | Q35211894 | ||
| Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130 | Q35777741 | ||
| Interleukin 4 expressed in situ selectively alters thymocyte development | Q36229764 | ||
| A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis | Q36371158 | ||
| CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation | Q36376179 | ||
| Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. | Q36735213 | ||
| Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts | Q36975390 | ||
| SOCS3 regulates the plasticity of gp130 signaling | Q38354507 | ||
| SOCS3 negatively regulates IL-6 signaling in vivo | Q38354512 | ||
| SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation | Q39698984 | ||
| Cytokine receptor signalling | Q40416594 | ||
| Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation | Q40642728 | ||
| A regulatory role for suppressor of cytokine signaling-1 in T(h) polarization in vivo | Q40693567 | ||
| Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice | Q40705435 | ||
| Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance | Q40743352 | ||
| Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs | Q40801352 | ||
| The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. | Q40816941 | ||
| LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. | Q40910796 | ||
| Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells | Q42286408 | ||
| A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production | Q42944831 | ||
| Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation. | Q43949091 | ||
| Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. | Q44021327 | ||
| Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling | Q44123776 | ||
| A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1). | Q44391338 | ||
| A critical role for Stat3 signaling in immune tolerance | Q44589709 | ||
| IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages | Q46376203 | ||
| SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses | Q47777274 | ||
| Suppressor of cytokine signaling 1 regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes. | Q52006064 | ||
| SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. | Q52174469 | ||
| Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1 | Q56899149 | ||
| Suppressor of Cytokine Signaling-1 Has IFN- -Independent Actions in T Cell Homeostasis | Q57227836 | ||
| Suppressor of Cytokine Signaling-1 Regulates Signaling in Response to Interleukin-2 and Other γc-dependent Cytokines in Peripheral T Cells | Q62819390 | ||
| Negative Regulation of Interleukin-12 Signaling by Suppressor of Cytokine Signaling-1 | Q62819402 | ||
| Neutralization of interferon-gamma in neonatal SOCS1-/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease | Q74566444 | ||
| Dual effects of suppressor of cytokine signaling (SOCS-2) on growth hormone signal transduction | Q77993656 | ||
| SOCS1/JAB is a negative regulator of LPS-induced macrophage activation | Q78518643 | ||
| SOCS-1 participates in negative regulation of LPS responses | Q78518680 | ||
| Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells | Q78806915 | ||
| Suppressor of Cytokine Signaling-1 Is Essential for Suppressing Dendritic Cell Activation and Systemic Autoimmunity | Q79073423 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1169-1176 | |
| P577 | publication date | 2003-12-01 | |
| P1433 | published in | Nature Immunology | Q1071725 |
| P1476 | title | Suppressors of cytokine signaling and immunity | |
| P478 | volume | 4 |
| Q39799474 | 12-O-tetradecanoylphorbol-13-acetate inhibits melanoma growth by inactivation of STAT3 through protein kinase C-activated tyrosine phosphatase(s) |
| Q36302666 | A MyD88-JAK1-STAT1 complex directly induces SOCS-1 expression in macrophages infected with Group A Streptococcus |
| Q64079625 | A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy |
| Q64060301 | A balanced game: chicken macrophage response to ALV-J infection |
| Q35222475 | A critical role for SOCS3 in innate resistance to Toxoplasma gondii |
| Q33330494 | A logic-based diagram of signalling pathways central to macrophage activation |
| Q64938127 | A systems immunology approach identifies the collective impact of 5 miRs in Th2 inflammation. |
| Q51053343 | A tritherapy combination of a fusion protein vaccine with immune-modulating doses of sequential chemotherapies in an optimized regimen completely eradicates large tumors in mice. |
| Q41774568 | Activation of protein kinase Calpha by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein beta-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells. |
| Q28583520 | Adiponectin activation of AMPK disrupts leptin-mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS-3) |
| Q54977185 | Adoptive Transfer of Interleukin-21-stimulated Human CD8+ T Memory Stem Cells Efficiently Inhibits Tumor Growth. |
| Q54569365 | Allogeneic activation is attenuated in a model of mouse lung perfused with magnesium-deficient blood. |
| Q46350343 | Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons. |
| Q93014137 | Amyloids in Site-Specific Autoimmune Reactions and Inflammatory Responses |
| Q25256583 | An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells |
| Q48908105 | Analysis of extracellular signal-regulated kinase 2 function in neural stem/progenitor cells via nervous system-specific gene disruption. |
| Q34550268 | Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes. |
| Q34139124 | Antiviral responses in mouse embryonic stem cells: differential development of cellular mechanisms in type I interferon production and response |
| Q54573052 | Association of neuropeptides with Th1/Th2 balance and allergic sensitization in children. |
| Q47927346 | Asthma: new developments in cytokine regulation |
| Q85344668 | Astragalin Attenuates Allergic Inflammation in a Murine Asthma Model |
| Q36199901 | Attenuated Innate Immunity in Embryonic Stem Cells and Its Implications in Developmental Biology and Regenerative Medicine |
| Q28589369 | BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2 |
| Q35919140 | Bacterial extract OM-85 BV protects mice against experimental chronic rhinosinusitis. |
| Q43807014 | Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing suppressor of cytokine signalling-1 (SOCS-1). |
| Q50896575 | CIS: the late-blooming eldest son. |
| Q37168160 | Can the immune system be harnessed to repair the CNS? |
| Q61813961 | Cancer Immunotherapy: Silencing Intracellular Negative Immune Regulators of Dendritic Cells |
| Q37689046 | Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth |
| Q38389332 | Carp edema virus/Koi sleepy disease: an emerging disease in Central-East Europe. |
| Q34028060 | Cellular and molecular basis for the regulation of inflammation by TGF-beta |
| Q39669203 | Cerebral preconditioning using cortical application of hypertonic salt solutions: upregulation of mRNAs encoding inhibitors of inflammation |
| Q39277283 | Combining MPDL3280A with adoptive cell immunotherapy exerts better antitumor effects against cervical cancer |
| Q41939112 | Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics |
| Q50726567 | Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. |
| Q31080044 | Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus |
| Q38997587 | Continuous time Bayesian networks identify Prdm1 as a negative regulator of TH17 cell differentiation in humans |
| Q40555249 | Crosstalk between PKCzeta and the IL4/Stat6 pathway during T-cell-mediated hepatitis |
| Q36691086 | Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. |
| Q37438637 | Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis |
| Q40315469 | Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections |
| Q36617125 | Cytokines in type 2 diabetes. |
| Q37147102 | DNA methylation in nasal epithelial cells from smokers: identification of ULBP3-related effects |
| Q28267996 | Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer |
| Q92398568 | Decoding inflammation, its causes, genomic responses, and emerging countermeasures |
| Q43468951 | Decreased SOCS1 mRNA expression levels in peripheral blood mononuclear cells from patients with systemic lupus erythematosus in a Chinese population |
| Q47151871 | Defective Suppressor of Cytokine Signaling 1 Signaling Contributes to the Pathogenesis of Systemic Lupus Erythematosus |
| Q36229426 | Dendritic cell quiescence during systemic inflammation driven by LPS stimulation of radioresistant cells in vivo |
| Q36436168 | Dendritic cell-based tumor vaccines and antigen presentation attenuators |
| Q92440947 | Differential Transcription of SOCS5 and SOCS7 in Multiple Sclerosis Patients Treated with Interferon Beta or Glatiramer Acetate |
| Q33771100 | Differential expression and potential role of SOCS1 and SOCS3 in Wallerian degeneration in injured peripheral nerve |
| Q54613582 | Differential expression of CD126 and CD130 mediates different STAT-3 phosphorylation in CD4+CD25- and CD25high regulatory T cells. |
| Q84580749 | Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity |
| Q23909718 | Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure |
| Q37913363 | Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections |
| Q37256528 | Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice |
| Q35176382 | Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range. |
| Q42205530 | Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. |
| Q45921962 | Dynamic expression of the suppressor of cytokine signaling-3 and cytokines in the cerebral basilar artery of rats with subarachnoid hemorrhage, and the effect of acetylcholine. |
| Q28727511 | Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines |
| Q28509208 | E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptors |
| Q51016636 | Effect of caffeic acid phenethyl ester on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. |
| Q24813993 | Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells |
| Q46912019 | Effect of ovariectomy on cardiac gene expression: inflammation and changes in SOCS gene expression |
| Q60923176 | Effects of thyroid-stimulating hormone on adhesion molecules and pro-inflammatory cytokines secretion in human umbilical vein endothelial cells |
| Q50130525 | Efficacy of intracellular immune checkpoint-silenced DC vaccine. |
| Q55314046 | Emergence of Leptin in Infection and Immunity: Scope and Challenges in Vaccines Formulation. |
| Q36661273 | Emerging mechanisms of immunosuppression in oral cancers |
| Q39994152 | Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism |
| Q54418379 | Endotoxin-induced lung injury in α-galactosylceramide-sensitized mice is caused by failure of interleukin-4 production in lung natural killer T cells. |
| Q38284703 | Engineering better immunotherapies via RNA interference |
| Q38694852 | Epigenetic alterations underlying autoimmune diseases |
| Q37933446 | Epigenetics and psoriasis |
| Q33650938 | Epstein-Barr Virus Interferes with the Amplification of IFNα Secretion by Activating Suppressor of Cytokine Signaling 3 in Primary Human Monocytes |
| Q30445485 | Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells |
| Q33717808 | Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes |
| Q36761824 | Expression of SOCS1 and SOCS3 genes in human graft-versus-host disease after allogeneic hematopoietic stem cell transplantation |
| Q41468278 | Expression of the SOCS family in human chronic wound tissues: Potential implications for SOCS in chronic wound healing |
| Q33897894 | Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3. |
| Q42241238 | FoxP3 provides competitive fitness to CD4⁺CD25⁺ T cells in leprosy patients via transcriptional regulation |
| Q34626052 | Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses |
| Q35817342 | Functional Impairment of Myeloid Dendritic Cells during Advanced Stage of HIV-1 Infection: Role of Factors Regulating Cytokine Signaling |
| Q57273099 | Functional Polymorphism in theSuppressor of Cytokine Signaling 1Gene Associated with Adult Asthma |
| Q36202888 | Gastrointestinal disease in simian immunodeficiency virus-infected rhesus macaques is characterized by proinflammatory dysregulation of the interleukin-6-Janus kinase/signal transducer and activator of transcription3 pathway |
| Q41831288 | Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes |
| Q39190247 | Gene methylation and silencing of SOCS3 in mantle cell lymphoma |
| Q36267259 | Genes and susceptibility to leishmaniasis |
| Q42155017 | Genetic variations in the SOCS3 gene in patients with Graves' ophthalmopathy |
| Q38324435 | Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes. |
| Q36876370 | Green tea catechins inhibit angiogenesis through suppression of STAT3 activation |
| Q35997118 | Growth factors in inflammatory bowel disease: the actions and interactions of growth hormone and insulin-like growth factor-I. |
| Q44363247 | HIV interferes with SOCS-1 and -3 expression levels driving immune activation |
| Q33747593 | HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1) |
| Q92062395 | Hepatic progenitor cell activation is induced by the depletion of the gut microbiome in mice |
| Q24806140 | Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function |
| Q40097568 | Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways |
| Q37389753 | Human suppressor of cytokine signaling 1 controls immunostimulatory activity of monocyte-derived dendritic cells |
| Q41841012 | IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice |
| Q37211125 | IL-4 confers resistance to IL-27-mediated suppression on CD4+ T cells by impairing signal transducer and activator of transcription 1 signaling |
| Q40261012 | IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites |
| Q41677262 | IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression |
| Q53505333 | Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. |
| Q56898193 | Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance |
| Q26744094 | Immunotherapy for human papillomavirus-associated disease and cervical cancer: review of clinical and translational research |
| Q42358876 | Improved Antitumor Activity of a Therapeutic Melanoma Vaccine through the Use of the Dual COX-2/5-LO Inhibitor Licofelone |
| Q38500702 | Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation |
| Q54424759 | Increased expression of suppressor of cytokine signaling 1 mRNA in patients with rheumatoid arthritis. |
| Q37226913 | Increased expression of suppressor of cytokine signaling-1 (SOCS-1): A mechanism for dysregulated T helper-1 responses in HIV-1 disease |
| Q47140124 | Inferring gene and protein interactions using PubMed citations and consensus Bayesian networks. |
| Q34894445 | Inflammatory process of CD8+ CD28- T cells in induced sputum from asthmatic patients |
| Q33383235 | Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression |
| Q37247082 | Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy |
| Q36289108 | Information networks in the mammary gland. |
| Q35951508 | Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance |
| Q34033910 | Inhibitory RNA molecules in immunotherapy for cancer |
| Q41282268 | Innate immunity in pluripotent human cells: attenuated response to interferon-β. |
| Q46602150 | Insights into gene expression profiles induced by Socs3 depletion in keratinocytes |
| Q36935522 | Interaction of hepatitis C virus with the type I interferon system |
| Q34594792 | Interference of suppressor of cytokine signaling 3 promotes epithelial-mesenchymal transition in MHCC97H cells |
| Q35913007 | Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells |
| Q35658377 | Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2. |
| Q35073912 | Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3. |
| Q46025003 | Interleukin-15 stimulates macrophages to activate CD4+ T cells: a role in the pathogenesis of rheumatoid arthritis? |
| Q35155990 | Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex |
| Q33560131 | Intracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling |
| Q81105362 | Knocking the SOCS1 off dendritic cells |
| Q37373008 | Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation |
| Q36680938 | Leptin-based adjuvants: an innovative approach to improve vaccine response |
| Q90314834 | Leukemia Inhibitory Factor Inhibits Plasmacytoid Dendritic Cell Function and Development |
| Q42766950 | Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1 |
| Q86530888 | Mesenchymal stem cells inhibit Th17 cells differentiation via IFN-γ-mediated SOCS3 activation |
| Q41240274 | Methylation and microRNA-mediated epigenetic regulation of SOCS3. |
| Q34154772 | Methylation profiling of SOCS1, SOCS2, SOCS3, CISH and SHP1 in Philadelphia-negative myeloproliferative neoplasm |
| Q36671852 | MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis |
| Q37393263 | MicroRNAs and Epithelial Immunity |
| Q37141220 | MicroRNAs: novel regulators in skin inflammation |
| Q43437633 | Misregulation of suppressors of cytokine signaling in eosinophilic esophagitis |
| Q24299367 | Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages |
| Q34554357 | Modulation of Toll-interleukin 1 receptor mediated signaling |
| Q37052050 | Molecular basis of oncostatin M-induced SOCS-3 expression in astrocytes |
| Q30390170 | Molecular characterization of in vivo adjuvant activity in ferrets vaccinated against influenza virus |
| Q39777644 | Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1). |
| Q37022886 | Myeloid depletion of SOCS3 enhances LPS-induced acute lung injury through CCAAT/enhancer binding protein δ pathway |
| Q35347976 | NF-κB and STAT3 - key players in liver inflammation and cancer |
| Q33682330 | NOD1 modulates IL-10 signalling in human dendritic cells |
| Q36231107 | Negative regulation of cytokine and TLR signalings by SOCS and others |
| Q81133805 | Negative regulation of cytokine signaling |
| Q24816896 | Negative regulation of cytokine signaling and immune responses by SOCS proteins |
| Q36485165 | New drugs targeting Th2 lymphocytes in asthma |
| Q34099855 | New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries |
| Q57406718 | New perspectives of Lactobacillus plantarum as a probiotic: The gut-heart-brain axis |
| Q61812442 | Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between Obesity and Inflammation-Driven Liver and Colorectal Cancers |
| Q28542802 | Olmesartan decreased levels of IL-1β and TNF-α, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model |
| Q52571885 | Osteoblast differentiation is impaired in SOCS-1-deficient mice. |
| Q54629846 | Overexpression of the suppressor of cytokine signalling 3 (SOCS3) in severe atopic dermatitis. |
| Q37620186 | PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis |
| Q54363541 | Paeoniflorin Suppressed High Glucose-Induced Retinal Microglia MMP-9 Expression and Inflammatory Response via Inhibition of TLR4/NF-κB Pathway Through Upregulation of SOCS3 in Diabetic Retinopathy. |
| Q38020769 | Particulate systems for targeting of macrophages: basic and therapeutic concepts. |
| Q36243982 | Pathological role of IL-6 in the experimental allergic bronchial asthma in mice |
| Q40548422 | Peroxiredoxin 1 Contributes to Host Defenses against Mycobacterium tuberculosis. |
| Q91741830 | Phosphorylated STAT3 expression linked to SOCS3 methylation is associated with proliferative ability of gastric mucosa in patients with early gastric cancer |
| Q91889657 | Porcine Reproductive and Respiratory Syndrome Virus Enhances Self-Replication via AP-1-Dependent Induction of SOCS1 |
| Q42116196 | Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells |
| Q41071671 | Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (SOCS3). |
| Q38857818 | Preventing Overheating: Tight Control of Gut Innate Immunity in Health and Disease |
| Q33858381 | Prognoses of patients with acute-on-chronic hepatitis B liver failure are closely associated with altered SOCS1 mRNA expression and cytokine production following glucocorticoid treatment. |
| Q34754932 | Programmed death 1 and cytokine inducible SH2-containing protein dependent expansion of regulatory T cells upon stimulation With Mycobacterium tuberculosis |
| Q92256920 | Prolonged Release and Functionality of Interleukin-10 Encapsulated within PLA-PEG Nanoparticles |
| Q35017646 | Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance |
| Q41204113 | Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue |
| Q86077790 | Protection of intestinal injury during heat stroke in mice by interleukin-6 pretreatment |
| Q37268557 | Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis. |
| Q42030398 | Pulmonary microRNA profiling in a mouse model of ventilator-induced lung injury |
| Q51759144 | Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype. |
| Q36983827 | RNA interference-mediated in vivo silencing of fas ligand as a strategy for the enhancement of DNA vaccine potency |
| Q37598112 | RNA interference: a potent technology in studying and modulating of dendritic cells, and potential in clinical therapy. |
| Q42977335 | Recipient IL28B polymorphism is an important independent predictor of posttransplant diabetes mellitus in liver transplant patients with chronic hepatitis C. |
| Q52689527 | Regulation of T-Cell Signaling by Post-Translational Modifications in Autoimmune Disease. |
| Q44967205 | Regulation of eotaxin-3/CC chemokine ligand 26 expression by T helper type 2 cytokines in human colonic myofibroblasts |
| Q43104640 | Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase. |
| Q38909429 | Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis |
| Q37965220 | Regulation of the inflammatory response of vascular endothelial cells by EPAC1. |
| Q37062216 | Relevance of Interferon Regulatory Factor-8 Expression in Myeloid-Tumor Interactions |
| Q37949289 | Role of SOCS1 in tumor progression and therapeutic application |
| Q86029959 | Role of Suppressor of Cytokine Signaling 3 in the Immune Modulation of Mesenchymal Stromal Cells |
| Q28071830 | Role of an imbalanced miRNAs axis in pathogenesis of psoriasis: novel perspectives based on review of the literature |
| Q81419045 | SOCS in situ expression in tuberculous lymphadenitis in an endemic area |
| Q38065534 | SOCS proteins in infectious diseases of mammals. |
| Q36831668 | SOCS proteins, cytokine signalling and immune regulation |
| Q38193362 | SOCS signaling in autoimmune diseases: molecular mechanisms and therapeutic implications |
| Q35927538 | SOCS, Inflammation, and Autoimmunity |
| Q64376943 | SOCS-1 Suppresses Inflammation Through Inhibition of NALP3 Inflammasome Formation in Smoke Inhalation-Induced Acute Lung Injury |
| Q64376760 | SOCS-1 inhibits TNF-alpha-induced cardiomyocyte apoptosis via ERK1/2 pathway activation |
| Q39594973 | SOCS-3 antagonizes pro-apoptotic effects of TRAIL and resveratrol in prostate cancer cells |
| Q22001519 | SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation |
| Q35226610 | SOCS1 and SOCS3 are expressed in mononuclear cells in human cytomegalovirus viremia after allogeneic hematopoietic stem cell transplantation |
| Q39831884 | SOCS1 protects protein tyrosine phosphatases by thioredoxin upregulation and attenuates Jaks to suppress ROS-mediated apoptosis. |
| Q31161219 | SOCS1 regulates the immune modulatory properties of mesenchymal stem cells by inhibiting nitric oxide production |
| Q34211024 | SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling |
| Q40366547 | SOCS2 can enhance interleukin-2 (IL-2) and IL-3 signaling by accelerating SOCS3 degradation |
| Q33506625 | SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation. |
| Q33697768 | SOCS3 deletion in T lymphocytes suppresses development of chronic ocular inflammation via upregulation of CTLA-4 and expansion of regulatory T cells |
| Q39089939 | SOCS3 expression correlates with severity of inflammation, expression of proinflammatory cytokines, and activation of STAT3 and p38 MAPK in LPS-induced inflammation in vivo. |
| Q37725585 | SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B. |
| Q63383863 | SOCS3 is required to temporally fine-tune photoreceptor cell differentiation |
| Q47796841 | SOCS3 participates in cholinergic pathway regulation of synovitis in rheumatoid arthritis. |
| Q33779510 | SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction |
| Q37592325 | SOCS3, a Major Regulator of Infection and Inflammation. |
| Q82493403 | SOCS5 and SOCS6 have similar expression patterns in normal and cancer tissues |
| Q42096170 | STAT3 Activities and Energy Metabolism: Dangerous Liaisons. |
| Q33623947 | STAT3 and epithelial-mesenchymal transitions in carcinomas |
| Q36871967 | STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses |
| Q38536624 | STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance |
| Q29547203 | STATs in cancer inflammation and immunity: a leading role for STAT3 |
| Q91997450 | STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion |
| Q41954125 | Salmonella pathogenicity island 2-dependent expression of suppressor of cytokine signaling 3 in macrophages |
| Q35103140 | Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency. |
| Q57077884 | Signal transduction in the type I interferon system and viral countermeasures |
| Q36492439 | Signal transduction of inflammatory cytokines and tumor development |
| Q36562969 | Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. |
| Q35071210 | Signaling by retinol and its serum binding protein |
| Q35478457 | Signaling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis |
| Q35108316 | Silenced suppressor of cytokine signaling 1 (SOCS1) enhances the maturation and antifungal immunity of dendritic cells in response to Candida albicans in vitro |
| Q40488939 | Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity |
| Q58326709 | Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting multiple sclerosis |
| Q33250007 | Single-walled carbon nanotubes-mediated in vivo and in vitro delivery of siRNA into antigen-presenting cells |
| Q65001289 | Sjogren's Syndrome and TAM Receptors: A Possible Contribution to Disease Onset. |
| Q34951617 | Social isolation impairs oral palatal wound healing in sprague-dawley rats: a role for miR-29 and miR-203 via VEGF suppression |
| Q46605002 | Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway |
| Q55003884 | Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies. |
| Q47386577 | Structure-activity studies of peptidomimetics based on kinase-inhibitory region of suppressors of cytokine signaling 1. |
| Q34314006 | Subversion of host cellular functions by the apicomplexan parasites |
| Q35192650 | Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance |
| Q36195649 | Suppressive effect of 19-nor-1α-25-dihydroxyvitamin D2 on gastric cancer cells and peritoneal metastasis model |
| Q57166981 | Suppressor of Cytokine Signaling 1 (SOCS1) and SOCS3 Are Stimulated within the Eye during Experimental Murine Cytomegalovirus Retinitis in Mice with Retrovirus-Induced Immunosuppression |
| Q34810532 | Suppressor of cytokine signaling 1 (SOCS1) mitigates anterior uveitis and confers protection against ocular HSV-1 infection |
| Q50278499 | Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-gamma. |
| Q33387801 | Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus |
| Q36600347 | Suppressor of cytokine signaling 1 inhibition strategy to enhance anti-HIV vaccination |
| Q46697159 | Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells. |
| Q45345628 | Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity |
| Q36395750 | Suppressor of cytokine signaling 3 (SOCS3) in Th2 cells evokes Th2 cytokines, IgE, and eosinophilia |
| Q34333533 | Suppressor of cytokine signaling 3 inhibits LPS-induced IL-6 expression in osteoblasts by suppressing CCAAT/enhancer-binding protein {beta} activity |
| Q35221160 | Suppressor of cytokine signaling-1 (SOCS1) inhibits lymphocyte recruitment into the retina and protects SOCS1 transgenic rats and mice from ocular inflammation |
| Q45775662 | Suppressor of cytokine signaling-1 reduces high glucose-induced TGF-beta1 and fibronectin synthesis in human mesangial cells |
| Q37455362 | Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function |
| Q35101723 | Suppressors of cytokine signaling 3 expression in eosinophils: regulation by PGE₂ and Th2 cytokines |
| Q36388792 | Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing |
| Q47785124 | TARC/CCL17 gene polymorphisms and expression associated with susceptibility and coronary artery aneurysm formation in Kawasaki disease. |
| Q37777380 | TGF-β Function in Immune Suppression |
| Q41897840 | TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2. |
| Q47352598 | TRIM8: Making the Right Decision between the Oncogene and Tumour Suppressor Role. |
| Q38047645 | Targeting the host or the virus: current and novel concepts for antiviral approaches against influenza virus infection |
| Q35543558 | Targeting the immunoregulator SRA/CD204 potentiates specific dendritic cell vaccine-induced T-cell response and antitumor immunity |
| Q61805129 | The Functions and Mechanism of a New Oligopeptide BP9 from Avian Bursa on Antibody Responses, Immature B Cell, and Autophagy |
| Q38792930 | The Inflammatory Response in Psoriasis: a Comprehensive Review |
| Q33566310 | The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet |
| Q35989418 | The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo |
| Q37148069 | The Thyroid Hormone Receptors Inhibit Hepatic Interleukin-6 Signaling During Endotoxemia |
| Q46646334 | The adjuvant effect of levamisole on killed viral vaccines |
| Q40470833 | The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits Porphyromonas gingivalis-induced expression of interleukin-8 by oral keratinocytes |
| Q46907819 | The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase |
| Q36796472 | The central role of wear debris in periprosthetic osteolysis |
| Q35803456 | The inhibition of lipopolysaccharide-induced macrophage inflammation by 4 compounds in Hypericum perforatum extract is partially dependent on the activation of SOCS3 |
| Q36346824 | The interferon response circuit: induction and suppression by pathogenic viruses |
| Q38902037 | The siRNA cocktail targeting interleukin 10 receptor and transforming growth factor-β receptor on dendritic cells potentiates tumour antigen-specific CD8(+) T cell immunity |
| Q36736188 | The target tissue in autoimmunity--an influential niche |
| Q42787245 | Therapeutic Potential for Targeting the Suppressor of Cytokine Signalling-1 Pathway for the Treatment of SLE. |
| Q45780399 | Therapeutic hope for psoriasis offered by SOCS (suppressor of cytokine signaling) mimetic peptide |
| Q49991844 | Time-dependent LXR/RXR pathway modulation characterizes capillary remodeling in inflammatory corneal neovascularization. |
| Q37401744 | Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. |
| Q35930484 | Topical administration of a suppressor of cytokine signaling-1 (SOCS1) mimetic peptide inhibits ocular inflammation and mitigates ocular pathology during mouse uveitis |
| Q38346243 | Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition |
| Q37760477 | Transcriptional regulation of T helper 17 cell differentiation |
| Q40050488 | Transcriptome profiling of antiviral immune and dietary fatty acid dependent responses of Atlantic salmon macrophage-like cells |
| Q43202271 | Tumor necrosis factor-a augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradation |
| Q41852651 | Type I diabetes-associated tolerogenic properties of interleukin-2. |
| Q37034487 | Understanding signaling cascades in melanoma |
| Q38916829 | Utilization of different anti-viral mechanisms by mammalian embryonic stem cells and differentiated cells |
| Q34742146 | Viral exploitation of host SOCS protein functions |
| Q51335017 | Vitamin A Transport and Cell Signaling by the Retinol-Binding Protein Receptor STRA6. |
| Q55492703 | [The Role of SOCS in the Development of Tumors]. |
| Q33975103 | c-MYC functions as a molecular switch to alter the response of human mammary epithelial cells to oncostatin M. |
| Q35222270 | c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. |
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