| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1024024586 |
| P356 | DOI | 10.1038/NRC1612 |
| P698 | PubMed publication ID | 15864282 |
| P2093 | author name string | Patrick J Casey | |
| Ann M Winter-Vann | |||
| P2860 | cites work | Cloning and characterization of a mammalian prenyl protein-specific protease | Q22009066 |
| Isoprenylcysteine carboxyl methyltransferase deficiency in mice | Q24290644 | ||
| Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity | Q24305492 | ||
| Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum | Q24321665 | ||
| LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo | Q24531930 | ||
| Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis | Q24554290 | ||
| Intracellular localization of the P21rho proteins | Q24642838 | ||
| Inflammation and cancer | Q24649640 | ||
| Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate | Q24671288 | ||
| A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation | Q24671540 | ||
| Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding | Q24674800 | ||
| Cell signaling by receptor tyrosine kinases | Q27860474 | ||
| Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage | Q27931598 | ||
| The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities | Q27935653 | ||
| Modulation of Ras and a-factor function by carboxyl-terminal proteolysis | Q27936659 | ||
| The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane | Q27937876 | ||
| Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules | Q28138265 | ||
| Creation of human tumour cells with defined genetic elements | Q28141602 | ||
| Protein prenyltransferases | Q28277579 | ||
| Guilty as charged: B-RAF is a human oncogene | Q28288202 | ||
| Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release | Q28301699 | ||
| Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases | Q28302743 | ||
| Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells | Q28506731 | ||
| Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells | Q28586789 | ||
| Prenylcysteine carboxylmethyltransferase is essential for the earliest stages of liver development in mice | Q28593403 | ||
| Small GTP-binding proteins | Q29547372 | ||
| RHO-GTPases and cancer | Q29616099 | ||
| Protein prenylation: molecular mechanisms and functional consequences | Q29618038 | ||
| Selective inhibition of ras-transformed cell growth by a novel fatty acid-based chloromethyl ketone designed to target Ras endoprotease | Q33833368 | ||
| Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi | Q34061239 | ||
| Autocrine and paracrine signaling through neuropeptide receptors in human cancer | Q34225976 | ||
| Heterotrimeric G-protein betagamma-dimers in growth and differentiation | Q34226052 | ||
| On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. | Q34277651 | ||
| Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation | Q34290291 | ||
| Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. | Q34298296 | ||
| S-Adenosylmethionine and methylation | Q34382111 | ||
| K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors | Q34427029 | ||
| Rho GTPases in transformation and metastasis. | Q34554757 | ||
| Farnesyltransferase inhibitors: promises and realities | Q34750418 | ||
| Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation | Q34792600 | ||
| Clinical significance of pleiotropic effects of statins: lipid reduction and beyond | Q34946380 | ||
| Lamins: building blocks or regulators of gene expression? | Q34988332 | ||
| Methylation of a membrane protein involved in bacterial chemotaxis | Q35090988 | ||
| Rhebbing up mTOR: New Insights on TSC1 and TSC2, and the Pathogenesis of Tuberous Sclerosis | Q35582348 | ||
| Signal events: Cell signal transduction and its inhibition in cancer | Q35606195 | ||
| Perspectives on farnesyl transferase inhibitors in cancer therapy | Q35687922 | ||
| Prenyl-binding domains: potential targets for Ras inhibitors and anti-cancer drugs | Q35818564 | ||
| Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro | Q35870698 | ||
| The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation. | Q36582083 | ||
| Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae | Q36727122 | ||
| Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR. | Q36819258 | ||
| Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity | Q37108753 | ||
| Farnesyl analogues inhibit vasoconstriction in animal and human arteries | Q37355259 | ||
| Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion | Q37357925 | ||
| Carboxyl methylation of Ras regulates membrane targeting and effector engagement | Q40609836 | ||
| Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic | Q40745426 | ||
| Assays of human postprenylation processing enzymes | Q40812496 | ||
| Inhibition of K-ras-transformed rodent and human cancer cell growth via induction of apoptosis by irreversible inhibitors of Ras endoprotease | Q40988935 | ||
| Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa | Q41069096 | ||
| Relationship between tissue levels of S-adenosylmethionine, S-adenosylhomocysteine, and transmethylation reactions | Q41485988 | ||
| CaaX converting enzymes | Q41749028 | ||
| Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates | Q41882877 | ||
| Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export | Q41977606 | ||
| Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems | Q42066922 | ||
| Farnesylcysteine analogues inhibit chemotactic peptide receptor-mediated G-protein activation in human HL-60 granulocyte membranes | Q42510557 | ||
| Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes | Q42605575 | ||
| RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription. | Q42799714 | ||
| Ras signalling on the endoplasmic reticulum and the Golgi | Q42815732 | ||
| Isoprenylcysteine carboxyl methyltransferase modulates endothelial monolayer permeability: involvement of RhoA carboxyl methylation | Q44709039 | ||
| The discovery of receptor tyrosine kinases: targets for cancer therapy | Q44879898 | ||
| Hematologic effects of inactivating the Ras processing enzyme Rce1. | Q46518410 | ||
| Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers. | Q52379805 | ||
| Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro. | Q54177555 | ||
| RAS oncogenes: the first 30 years. | Q55036584 | ||
| Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils | Q57731072 | ||
| Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding | Q59072746 | ||
| Identification of an isoprenylated cysteine methyl ester hydrolase activity in bovine rod outer segment membranes | Q68165502 | ||
| Inhibitors of the isoprenylated protein endoprotease | Q70585190 | ||
| Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease | Q71010144 | ||
| Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice | Q71803596 | ||
| Functional significance of beta gamma-subunit carboxymethylation for the activation of phospholipase C and phosphoinositide 3-kinase | Q72309438 | ||
| Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase | Q72413275 | ||
| Fractionation and characterization of protein C-terminal prenyl-cysteine methylesterase activities from rabbit brain | Q72625037 | ||
| Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes | Q72625599 | ||
| The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules | Q73010820 | ||
| Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1 | Q73521609 | ||
| Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine | Q73735641 | ||
| Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice | Q73738461 | ||
| Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases | Q73852862 | ||
| Substrate specificity of mammalian prenyl protein-specific endoprotease activity | Q74378121 | ||
| Opinion: Searching for the elusive targets of farnesyltransferase inhibitors | Q75312802 | ||
| P433 | issue | 5 | |
| P304 | page(s) | 405-412 | |
| P577 | publication date | 2005-05-01 | |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | Post-prenylation-processing enzymes as new targets in oncogenesis | |
| P478 | volume | 5 |
| Q38683208 | 10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins |
| Q38683207 | 9 Structure and function of isoprenylcysteine carboxylmethyltransferase (Icmt): A key enzyme in CaaX processing |
| Q37960375 | A journey under the sea: the quest for marine anti-cancer alkaloids |
| Q35266447 | A role for Rac3 GTPase in the regulation of autophagy |
| Q41035817 | A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes. |
| Q52675092 | Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma. |
| Q37055519 | Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection |
| Q34091952 | Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization |
| Q33246884 | Amide-substituted farnesylcysteine analogs as inhibitors of human isoprenylcysteine carboxyl methyltransferase |
| Q41887817 | An ABC transporter controls export of a Drosophila germ cell attractant |
| Q34781560 | An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering |
| Q27939423 | Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartment |
| Q42579212 | Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis |
| Q36708774 | Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter |
| Q36432441 | Cenp-F (mitosin) is more than a mitotic marker |
| Q89175973 | Chemical and Biochemical Perspectives of Protein Lysine Methylation |
| Q27937343 | Chemical inhibition of CaaX protease activity disrupts yeast Ras localization |
| Q90403070 | Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics |
| Q39154559 | Control of RhoA methylation by carboxylesterase I |
| Q89114866 | De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer |
| Q33604076 | Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling |
| Q37304601 | Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation |
| Q41075384 | Distinct functional relevance of dynamic GTPase cysteine methylation in fission yeast |
| Q36050056 | Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases. |
| Q35067883 | Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells |
| Q33843725 | Driven to death: Inhibition of farnesylation increases Ras activity and promotes growth arrest and cell death [corrected] |
| Q40071304 | Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors |
| Q47251070 | Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome. |
| Q90266976 | Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis |
| Q34056922 | Enlarging the scope of cell-penetrating prenylated peptides to include farnesylated 'CAAX' box sequences and diverse cell types |
| Q37388833 | Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease |
| Q24685451 | GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo |
| Q53619387 | Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function. |
| Q34519891 | Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice |
| Q47655012 | HMG-CoA reductase inhibition delays DNA repair and promotes senescence after tumor irradiation |
| Q37477703 | Heterologous expression studies of Saccharomyces cerevisiae reveal two distinct trypanosomatid CaaX protease activities and identify their potential targets |
| Q24671093 | Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis |
| Q28276671 | Human laminopathies: nuclei gone genetically awry |
| Q40131116 | Identification and validation of eukaryotic aspartate and glutamate methylation in proteins |
| Q28584989 | Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding |
| Q40282751 | Identifying off-target effects and hidden phenotypes of drugs in human cells |
| Q33439394 | In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I |
| Q35944601 | Inhibition of Ras for cancer treatment: the search continues |
| Q39681605 | Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth |
| Q35990361 | Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones |
| Q37961442 | Insights into the differences between the A- and B-type nuclear lamins. |
| Q54223105 | Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease. |
| Q39384869 | Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents |
| Q33886255 | Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms |
| Q96610035 | Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal |
| Q38963320 | Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism |
| Q33740505 | Loss of HMG-CoA reductase in C. elegans causes defects in protein prenylation and muscle mitochondria |
| Q45943224 | MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells. |
| Q39498514 | Matrix metalloproteinase-1 contribution to sarcoma cell invasion |
| Q33669995 | Measurement of protein farnesylation and geranylgeranylation in vitro, in cultured cells and in biopsies, and the effects of prenyl transferase inhibitors |
| Q27680718 | Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1 |
| Q28610521 | Membrane protein transport in photoreceptors: the function of PDEδ: the Proctor lecture |
| Q26799973 | Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link |
| Q92286998 | MicroRNAs Involved in Metastasis of Hepatocellular Carcinoma: Target Candidates, Functionality and Efficacy in Animal Models and Prognostic Relevance |
| Q33653120 | Modulation of the inhibitor properties of dipeptidyl (acyloxy)methyl ketones toward the CaaX proteases. |
| Q42790115 | Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites. |
| Q35842216 | N-Acetylfarnesylcysteine is a novel class of peroxisome proliferator-activated receptor γ ligand with partial and full agonist activity in vitro and in vivo |
| Q39091745 | N-Acetylglutaminoyl-S-farnesyl-L-cysteine (SIG-1191): an anti-inflammatory molecule that increases the expression of the aquaglyceroporin, aquaporin-3, in human keratinocytes |
| Q30617387 | Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction. |
| Q39841601 | Novel gene C17orf37 in 17q12 amplicon promotes migration and invasion of prostate cancer cells. |
| Q37144613 | Novel route to chaetomellic acid A and analogues: serendipitous discovery of a more competent FTase inhibitor |
| Q34136884 | Nuclear lamins |
| Q39474407 | PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. |
| Q37426883 | Phosphatase of regenerating liver-3 (PRL-3) is associated with metastasis and poor prognosis in gastric carcinoma |
| Q33408806 | Phosphatase of regenerating liver-3 localizes to cyto-membrane and is required for B16F1 melanoma cell metastasis in vitro and in vivo |
| Q92632702 | Polyisoprenylated Cysteinyl Amide Inhibitors Deplete K-Ras and Induce Caspase-dependent Apoptosis in Lung Cancer Cells |
| Q37650129 | Polyisoprenylated methylated protein methyl esterase overexpression and hyperactivity promotes lung cancer progression |
| Q100762044 | Post-translational modification of KRAS: potential targets for cancer therapy |
| Q36856455 | Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets |
| Q39191891 | Posttranslational isoprenylation of tryptophan in bacteria |
| Q24305028 | Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis |
| Q89996102 | Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences |
| Q91783165 | Protein Isoprenylation in Yeast Targets COOH-Terminal Sequences Not Adhering to the CaaX Consensus |
| Q33849385 | Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer. |
| Q37981563 | Protein farnesylation and disease |
| Q93106338 | Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions |
| Q38704283 | Protein prenylation: unique fats make their mark on biology |
| Q83937866 | Protein-fragment complementation assays (PCA) in small GTPase research and drug discovery |
| Q43709952 | Proteolytic processing of certain CaaX motifs can occur in the absence of the Rce1p and Ste24p CaaX proteases |
| Q35928477 | Quantitative structure-activity relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase |
| Q35008463 | RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments |
| Q42116254 | Rac-ing to the plasma membrane: the long and complex work commute of Rac1 during cell signaling |
| Q34061234 | Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues |
| Q50102683 | Rce1: mechanism and inhibition |
| Q37024839 | Recent discoveries in the genetics of melanoma and their therapeutic implications |
| Q37970568 | Regulating the regulator: post-translational modification of RAS |
| Q30494392 | Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1 |
| Q26995791 | Regulation of mTORC1 by PI3K signaling |
| Q41898753 | Regulation of polyisoprenylated methylated protein methyl esterase by polyunsaturated fatty acids and prostaglandins |
| Q37202275 | Regulation of protein prenyltransferase in central neurons |
| Q42434602 | Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification |
| Q34249114 | Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation |
| Q37377346 | Rho GTPases orient directional sensing in chemotaxis |
| Q38129373 | Rho-kinase: regulation, (dys)function, and inhibition |
| Q42735517 | Rho2 palmitoylation is required for plasma membrane localization and proper signaling to the fission yeast cell integrity mitogen- activated protein kinase pathway |
| Q37459898 | Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration |
| Q45786849 | S-carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation. |
| Q37845250 | Small GTPases and cilia |
| Q47271754 | Small change, big effect: taking RAS by the tail through suppression of post-prenylation carboxylmethylation |
| Q27932239 | Small-molecule inhibitors of the Rce1p CaaX protease |
| Q35188280 | Small-molecule modulation of Ras signaling |
| Q37698902 | SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers |
| Q37243140 | Solid-phase synthesis of prenylcysteine analogs |
| Q34284968 | Splice variants of SmgGDS control small GTPase prenylation and membrane localization |
| Q26745863 | Structural Mechanisms and Drug Discovery Prospects of Rho GTPases |
| Q30152692 | Structural basis for catalysis at the membrane-water interface. |
| Q28383033 | Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells |
| Q36107507 | Synthesis of desthio prenylcysteine analogs: sulfur is important for biological activity |
| Q36515556 | Synthetic isoprenoid analogues for the study of prenylated proteins: Fluorescent imaging and proteomic applications |
| Q50184556 | Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density |
| Q92663940 | Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy |
| Q29618155 | Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer |
| Q31111628 | The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus. |
| Q41920214 | The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylresorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus. |
| Q37622606 | The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif. |
| Q38962669 | The differential palmitoylation states of N-Ras and H-Ras determine their distinct Golgi subcompartment localizations. |
| Q26997789 | The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer |
| Q28000091 | The emerging role of Arf/Arl small GTPases in cilia and ciliopathies |
| Q36107479 | The isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase: development of novel inhibitors |
| Q35742306 | The mevalonate pathway in C. elegans |
| Q39967791 | The polybasic region of Rho GTPases defines the cleavage by Yersinia enterocolitica outer protein T (YopT). |
| Q36445794 | The prenyl-binding protein PrBP/δ: a chaperone participating in intracellular trafficking |
| Q36510458 | The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia |
| Q36673199 | The role of the lens actin cytoskeleton in fiber cell elongation and differentiation |
| Q33943379 | Therapeutic intervention based on protein prenylation and associated modifications |
| Q57060145 | Therapeutic strategies to target RAS-mutant cancers |
| Q37318355 | Topology of the yeast Ras converting enzyme as inferred from cysteine accessibility studies |
| Q38270808 | Understanding Protein Palmitoylation: Biological Significance and Enzymology |
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