| scholarly article | Q13442814 |
| P2093 | author name string | P. J. Casey | |
| E. Kim | |||
| S. G. Young | |||
| B. Taylor | |||
| K. Shannon | |||
| J. C. Otto | |||
| P. Ambroziak | |||
| M. Ashby | |||
| P2860 | cites work | Cloning and characterization of a mammalian prenyl protein-specific protease | Q22009066 |
| Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum | Q24321665 | ||
| Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases | Q24647831 | ||
| Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing | Q24670437 | ||
| Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines | Q24683034 | ||
| Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage | Q27931598 | ||
| Genetic analysis of yeast RAS1 and RAS2 genes. | Q27932104 | ||
| Modulation of Ras and a-factor function by carboxyl-terminal proteolysis | Q27936659 | ||
| Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product | Q27937733 | ||
| All ras proteins are polyisoprenylated but only some are palmitoylated | Q28270312 | ||
| Protein prenyltransferases | Q28277579 | ||
| A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor | Q28493191 | ||
| Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2 | Q28506189 | ||
| The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain | Q28586297 | ||
| ras genes | Q29547799 | ||
| Protein prenylation: molecular mechanisms and functional consequences | Q29618038 | ||
| Protein methylation. | Q34337295 | ||
| K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors | Q34427029 | ||
| K-ras is an essential gene in the mouse with partial functional overlap with N-ras | Q35192456 | ||
| Protein prenylation: genes, enzymes, targets, and functions. | Q35656726 | ||
| Protein isoprenylation and methylation at carboxyl-terminal cysteine residues | Q35671041 | ||
| Endoproteolytic processing of a farnesylated peptide in vitro | Q37019384 | ||
| A microsomal endoprotease that specifically cleaves isoprenylated peptides | Q37102283 | ||
| Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity | Q37108753 | ||
| Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation | Q37739922 | ||
| Death before birth: clues from gene knockouts and mutations | Q40514851 | ||
| Modification of eukaryotic signaling proteins by C-terminal methylation reactions | Q40815224 | ||
| Chemical biology of protein isoprenylation/methylation | Q40974704 | ||
| Analysis of Ras protein expression in mammalian cells | Q41388791 | ||
| Farnesyltransferase inhibitors versus Ras inhibitors. | Q47830137 | ||
| Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers. | Q52379805 | ||
| Mad Bet for Rab | Q59061245 | ||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Kirsten rat sarcoma viral oncogene homolog | Q21498354 |
| GTPase NRas | Q21989424 | ||
| P304 | page(s) | 8383–8390 | |
| P577 | publication date | 1999-03-26 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells | |
| P478 | volume | 274 |
| Q38683208 | 10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins |
| Q35878817 | 8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells. |
| Q24671540 | A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation |
| Q46981603 | A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17. |
| Q41035817 | A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes. |
| Q36513960 | ABI domain‐containing proteins contribute to surface protein display and cell division in Staphylococcus aureus |
| Q33740216 | Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. |
| Q34470636 | Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin |
| Q34290291 | Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation |
| Q36956839 | Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner |
| Q24792001 | Analysis of the kinetic mechanism of recombinant human isoprenylcysteine carboxylmethyltransferase (Icmt) |
| Q40812496 | Assays of human postprenylation processing enzymes |
| Q44556034 | AtFACE-2, a functional prenylated protein protease from Arabidopsis thaliana related to mammalian Ras-converting enzymes. |
| Q28588204 | Biochemical studies of Zmpste24-deficient mice |
| Q36194945 | Biogenesis of the Saccharomyces cerevisiae pheromone a-factor, from yeast mating to human disease |
| Q33923323 | Brain ischemia and reperfusion: molecular mechanisms of neuronal injury |
| Q52327318 | C-terminus Proteolysis and Palmitoylation Cooperate for Optimal Plasma Membrane Localization of RasA in Aspergillus fumigatus. |
| Q22009066 | Cloning and characterization of a mammalian prenyl protein-specific protease |
| Q46264996 | Deciphering lipid codes: K-Ras as a paradigm |
| Q39733353 | Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression |
| Q36863992 | Deficiency of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Leads to Progressive Loss of Photoreceptor Function |
| Q28588865 | Defining the importance of phosphatidylserine synthase 2 in mice |
| Q46620737 | Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway |
| Q33966782 | Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice |
| Q36050056 | Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases. |
| Q40312690 | Endoproteolytic processing of RhoA by Rce1 is required for the cleavage of RhoA by Yersinia enterocolitica outer protein T. |
| Q33914279 | Farnesylation of retinal transducin underlies its translocation during light adaptation |
| Q46473286 | Functional analysis of Arabidopsis postprenylation CaaX processing enzymes and their function in subcellular protein targeting |
| Q42784309 | Functional specificity of ras isoforms: so similar but so different |
| Q35679537 | GGPPS, a new EGR-1 target gene, reactivates ERK 1/2 signaling through increasing Ras prenylation |
| Q37138752 | Genetic analyses of the role of RCE1 in RAS membrane association and transformation. |
| Q53619387 | Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function. |
| Q33755858 | Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. |
| Q39451813 | H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway |
| Q35941280 | HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells. |
| Q34226052 | Heterotrimeric G-protein betagamma-dimers in growth and differentiation |
| Q42181249 | Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans. |
| Q24598824 | Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf |
| Q35944601 | Inhibition of Ras for cancer treatment: the search continues |
| Q35990361 | Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones |
| Q35958478 | Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24 |
| Q24290644 | Isoprenylcysteine carboxyl methyltransferase deficiency in mice |
| Q34251248 | Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. |
| Q35708595 | Methotrexate and Ras methylation: a new trick for an old drug? |
| Q35524497 | Mice that express farnesylated versions of prelamin A in neurons develop achalasia |
| Q33653120 | Modulation of the inhibitor properties of dipeptidyl (acyloxy)methyl ketones toward the CaaX proteases. |
| Q24611091 | Mutational analysis of the ras converting enzyme reveals a requirement for glutamate and histidine residues |
| Q33691054 | New insights into the interaction of Ras with the plasma membrane |
| Q34277651 | On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. |
| Q34246544 | Photoaffinity labeling of Ras converting enzyme 1 (Rce1p) using a benzophenone-containing peptide substrate |
| Q81703538 | Post-prenylation-processing enzymes as new targets in oncogenesis |
| Q33734499 | Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases |
| Q28272957 | Prelamin A farnesylation and progeroid syndromes |
| Q34457223 | Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis |
| Q24305028 | Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis |
| Q37981563 | Protein farnesylation and disease |
| Q38704283 | Protein prenylation: unique fats make their mark on biology |
| Q43709952 | Proteolytic processing of certain CaaX motifs can occur in the absence of the Rce1p and Ste24p CaaX proteases |
| Q33228701 | Proteomic analysis of bovine brain G protein gamma subunit processing heterogeneity |
| Q35008463 | RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments |
| Q100156045 | RCE1 cleaves S-Farn proRAS proteins |
| Q50336184 | Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation |
| Q35120159 | Ras proteins: different signals from different locations |
| Q33351823 | Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events. |
| Q35615842 | Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease |
| Q50102683 | Rce1: mechanism and inhibition |
| Q33889074 | Recent advances in the study of prenylated proteins |
| Q73487348 | Reconstitution of the Ste24p-dependent N-terminal proteolytic step in yeast a-factor biogenesis |
| Q36973165 | Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis |
| Q34166555 | Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24. |
| Q28255336 | Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma) |
| Q33278014 | Sequence dependence and differential expression of Ggamma5 subunit isoforms of the heterotrimeric G proteins variably processed after prenylation in mammalian cells |
| Q24644688 | Structure of mammalian protein geranylgeranyltransferase type-I |
| Q27677111 | Structure of the integral membrane protein CAAX protease Ste24p |
| Q28586789 | Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells |
| Q24671288 | Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate |
| Q29618155 | Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer |
| Q44012141 | The Arabidopsis AtSTE24 is a CAAX protease with broad substrate specificity |
| Q27935653 | The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities |
| Q39897100 | The abi proteins and their involvement in bacteriocin self-immunity |
| Q38740000 | The renewed battle against RAS-mutant cancers |
| Q33943379 | Therapeutic intervention based on protein prenylation and associated modifications |
| Q40472347 | Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase. |
| Q73852862 | Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases |
| Q35994954 | Type-I prenyl protease function is required in the male germline of Drosophila melanogaster |
| Q24328791 | USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity |
| Q34191451 | Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect. |
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