scholarly article | Q13442814 |
P356 | DOI | 10.1128/MCB.20.7.2475-2487.2000 |
P8608 | Fatcat ID | release_yw5ae3ml4bhnhp2eklsxtz27eq |
P932 | PMC publication ID | 85443 |
P698 | PubMed publication ID | 10713171 |
P50 | author | Robert G. Parton | Q30347571 |
P2093 | author name string | A Apolloni | |
I A Prior | |||
M Lindsay | |||
J F Hancock | |||
P2860 | cites work | Cloning and characterization of a mammalian prenyl protein-specific protease | Q22009066 |
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum | Q24321665 | ||
Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes | Q24336596 | ||
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation | Q24562853 | ||
Molecular cloning and characterization of a novel type of regulatory protein (GDI) for smg p25A, a ras p21-like GTP-binding protein | Q24598539 | ||
Rab11 regulates recycling through the pericentriolar recycling endosome | Q24681897 | ||
Functional rafts in cell membranes | Q27860768 | ||
The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins | Q27935631 | ||
Modulation of Ras and a-factor function by carboxyl-terminal proteolysis | Q27936659 | ||
A non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformation | Q28114914 | ||
Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi | Q28140190 | ||
Increasing complexity of Ras signaling. | Q53429989 | ||
The p21 ras C-terminus is required for transformation and membrane association | Q53551139 | ||
Translocation of Ki-ras p21 between membrane and cytoplasm by smg GDS | Q70575593 | ||
A polybasic domain allows nonprenylated Ras proteins to function in Saccharomyces cerevisiae | Q72136028 | ||
Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger | Q73555600 | ||
Colocalization of Ras and Ral on the membrane is required for Ras-dependent Ral activation through Ral GDP dissociation stimulator | Q73994488 | ||
Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase | Q77195536 | ||
Separation of "glycosphingolipid signaling domain" from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling | Q77631079 | ||
All ras proteins are polyisoprenylated but only some are palmitoylated | Q28270312 | ||
The complexity of Raf-1 regulation | Q28305850 | ||
Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells | Q28506731 | ||
Caveolin-3 associates with developing T-tubules during muscle differentiation | Q28511690 | ||
ER-to-Golgi transport visualized in living cells | Q29547526 | ||
ras oncogenes in human cancer: a review | Q29547769 | ||
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane | Q29618478 | ||
Activation of Raf as a result of recruitment to the plasma membrane | Q29618481 | ||
Regulation of RasGRP via a phorbol ester-responsive C1 domain. | Q31973953 | ||
Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis | Q33562770 | ||
Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. | Q33785693 | ||
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides | Q34219356 | ||
Mapping the distribution of Golgi enzymes involved in the construction of complex oligosaccharides | Q34300298 | ||
p21ras is modified by a farnesyl isoprenoid | Q34315409 | ||
Ras effectors and their role in mitogenesis and oncogenesis | Q34439160 | ||
The murine N-ras gene is not essential for growth and development | Q34650223 | ||
Control of the ERK MAP kinase cascade by Ras and Raf. | Q34662994 | ||
K-ras is an essential gene in the mouse with partial functional overlap with N-ras | Q35192456 | ||
Protein isoprenylation and methylation at carboxyl-terminal cysteine residues | Q35671041 | ||
Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro | Q36220495 | ||
Trafficking of an acylated cytosolic protein: newly synthesized p56(lck) travels to the plasma membrane via the exocytic pathway | Q36342168 | ||
Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae | Q36727122 | ||
N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization | Q38306703 | ||
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins | Q38316770 | ||
Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways | Q38354870 | ||
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. | Q39481540 | ||
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains | Q40918552 | ||
Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated. | Q40977491 | ||
Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies. | Q40982625 | ||
Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo | Q41054513 | ||
Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo | Q41069980 | ||
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins. | Q41083682 | ||
Prenylation and palmitoylation analysis | Q41388759 | ||
Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells. | Q41514986 | ||
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane | Q41715384 | ||
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane | Q41718569 | ||
Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking | Q42833741 | ||
Vesicular tubular clusters between the ER and Golgi mediate concentration of soluble secretory proteins by exclusion from COPI-coated vesicles | Q45345737 | ||
Microsomal membranes contain a high affinity binding site for prenylated peptides | Q48250254 | ||
Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers. | Q52379805 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2475-2487 | |
P577 | publication date | 2000-04-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway | |
P478 | volume | 20 |
Q38683208 | 10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins |
Q34174948 | A Ras by any other name |
Q44170732 | A cell-specific, prenylation-independent mechanism regulates targeting of type II RACs |
Q37234348 | A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes. |
Q36324079 | A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65 |
Q30416821 | A comprehensive survey of Ras mutations in cancer |
Q47985272 | A designed probe for acidic phospholipids reveals the unique enriched anionic character of the cytosolic face of the mammalian plasma membrane |
Q50707844 | A live cell, image-based approach to understanding the enzymology and pharmacology of 2-bromopalmitate and palmitoylation. |
Q93018032 | A model for RAS mutation patterns in cancers: finding the sweet spot |
Q39865031 | A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis. |
Q46981603 | A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17. |
Q30635394 | A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores |
Q57364518 | A role of Saccharomyces cerevisiae fatty Acid activation protein 4 in palmitoyl-CoA pool for growth in the presence of ethanol |
Q37336146 | ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment |
Q40014102 | Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion |
Q36956839 | Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner |
Q24601002 | Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors |
Q34825246 | Activation of small GTPases of the Ras and Rho family by growth factors active on mast cells |
Q36954216 | Activation of the MAPK module from different spatial locations generates distinct system outputs |
Q44856926 | Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting. |
Q34326437 | Alteration of EGFR spatiotemporal dynamics suppresses signal transduction. |
Q39670184 | Altered localization of H-Ras in caveolin-1-null cells is palmitoylation-independent |
Q36217387 | Amino-terminal cysteine residues differentially influence RGS4 protein plasma membrane targeting, intracellular trafficking, and function |
Q39314490 | Annexin A6 is a scaffold for PKCα to promote EGFR inactivation |
Q33917446 | Association of prenylated proteins with the plasma membrane and the inner nuclear membrane is mediated by the same membrane-targeting motifs |
Q81086860 | Biochemical and biophysical analyses of Ras modification by ubiquitin |
Q40609836 | Carboxyl methylation of Ras regulates membrane targeting and effector engagement |
Q24654811 | Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin |
Q57274190 | Caveolin and ras function |
Q40656012 | Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane |
Q33953511 | Cellular palmitoylation and trafficking of lipidated peptides |
Q40659447 | Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs |
Q39911337 | Cloning and functional analysis of farnesyl diphosphate synthase (FPPS) gene from Mylabris cichorii Cloning, functional analysis of McFPPS. |
Q36891374 | Clostridium sordellii Lethal-Toxin Autoprocessing and Membrane Localization Activities Drive GTPase Glucosylation Profiles in Endothelial Cells |
Q37401392 | Compartmentalized signalling: Ras proteins and signalling nanoclusters. |
Q47333014 | Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting |
Q37172538 | Conformational plasticity and navigation of signaling proteins in antigen-activated B lymphocytes |
Q30475853 | Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells |
Q27326381 | Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10 |
Q24306928 | DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras |
Q38238599 | Decoding RAS isoform and codon-specific signalling. |
Q36320736 | Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway |
Q51119632 | Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer. |
Q39476739 | Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design |
Q43139745 | Differences in Galpha12- and Galpha13-mediated plasma membrane recruitment of p115-RhoGEF. |
Q37415584 | Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination |
Q42807754 | Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization |
Q90411020 | Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins |
Q40816808 | Differential activation of the Rac pathway by Ha-Ras and K-Ras |
Q24653738 | Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups |
Q24674800 | Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding |
Q46620737 | Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway |
Q24311584 | Differential palmitoylation of the endosomal SNAREs syntaxin 7 and syntaxin 8 |
Q29396443 | Differential palmitoylation regulates intracellular patterning of SNAP25 |
Q33923711 | Discovery and characterization of inhibitors of human palmitoyl acyltransferases |
Q40540260 | Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen. |
Q40724839 | Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation |
Q40755894 | Down-regulation of MHC class I by bovine papillomavirus E5 oncoproteins |
Q39085228 | Dual role of the cysteine-string domain in membrane binding and palmitoylation-dependent sorting of the molecular chaperone cysteine-string protein. |
Q38702658 | Early and Late Induction of KRAS and HRAS Proto-Oncogenes by Reactive Oxygen Species in Primary Astrocytes. |
Q51775144 | Early endosome localization and activity of RasGEF1b, a toll-like receptor-inducible Ras guanine-nucleotide exchange factor. |
Q51798686 | Electrical properties of plasma membrane modulate subcellular distribution of K-Ras. |
Q24554279 | Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6 |
Q42074716 | Eomesodermin requires transforming growth factor-beta/activin signaling and binds Smad2 to activate mesodermal genes |
Q41789024 | Escorting Ras. |
Q37932506 | Exploring protein lipidation with chemical biology |
Q24297194 | Expression, purification and biochemical characterization of the N-terminal regions of human TIG3 and HRASLS3 proteins |
Q42724551 | FKBP12 binds to acylated H-ras and promotes depalmitoylation |
Q36559712 | Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission |
Q28585115 | Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation |
Q36608782 | Fluorescence-based methods to image palmitoylated proteins |
Q42784309 | Functional specificity of ras isoforms: so similar but so different |
Q40815505 | GTP-dependent segregation of H-ras from lipid rafts is required for biological activity |
Q36536538 | Galectin-1 is a novel structural component and a major regulator of h-ras nanoclusters |
Q34975601 | Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells |
Q42827129 | H-Ras does not need COP I- or COP II-dependent vesicular transport to reach the plasma membrane. |
Q46633545 | H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment. |
Q28564405 | H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis |
Q38899159 | H-ras distribution and signaling in plasma membrane microdomains are regulated by acylation and deacylation events |
Q34316824 | HIV-1 Nef: a multifaceted modulator of T cell receptor signaling |
Q96764442 | Haspin regulates Ras localization to promote Cdc24-driven mitotic depolarization |
Q52549569 | Heterotrimer formation, together with isoprenylation, is required for plasma membrane targeting of Gbetagamma. |
Q33689727 | Human RAS superfamily proteins and related GTPases |
Q24604409 | Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase |
Q34078624 | Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo |
Q44805571 | Identification of a novel domain of Ras and Rap1 that directs their differential subcellular localizations |
Q42818368 | Identification of essential interacting elements in K-Ras/calmodulin binding and its role in K-Ras localization |
Q34765540 | In TCR-stimulated T-cells, N-ras regulates specific genes and signal transduction pathways |
Q36608766 | In vitro and cellular assays for palmitoyl acyltransferases using fluorescent lipidated peptides |
Q33925229 | Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling |
Q34931245 | Insider information: how palmitoylation of Ras makes it a signaling double agent |
Q28208695 | Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1 |
Q57372567 | Intracellular Localization of Type III-deliveredPseudomonasExoS with Endosome Vesicles |
Q33769297 | Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner |
Q37401355 | Isoform-specific ras functions in development and cancer |
Q38731776 | K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target? |
Q40360081 | K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes |
Q38274959 | Kras Is Critical for B Cell Lymphopoiesis |
Q24669996 | Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin |
Q30441963 | Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation |
Q28476446 | Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics |
Q44915718 | Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. |
Q28183716 | Mechanisms of regulating the Raf kinase family |
Q38664174 | Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment |
Q35153478 | Membrane targeting of Rab GTPases is influenced by the prenylation motif |
Q34061239 | Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi |
Q35708595 | Methotrexate and Ras methylation: a new trick for an old drug? |
Q40375558 | Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line. |
Q44305996 | Molecular characterization of a rabbit long-chain fatty acyl CoA synthetase that is highly expressed in the vascular endothelium |
Q42364777 | Multiple Cellular Proteins Modulate the Dynamics of K-ras Association with the Plasma Membrane |
Q52598820 | Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability. |
Q44620591 | Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells |
Q37460012 | Nucleophosmin and nucleolin regulate K-Ras plasma membrane interactions and MAPK signal transduction |
Q34277651 | On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. |
Q40203762 | Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex |
Q36103287 | Oncogenic Ras in tumour progression and metastasis |
Q24339398 | PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus |
Q38765858 | PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization. |
Q90256056 | PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity |
Q34191596 | Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis. |
Q35920861 | Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae |
Q37377694 | Palmitoylation cycles and regulation of protein function (Review). |
Q42111091 | Palmitoylation pilots ras to recycling endosomes |
Q42325460 | Palmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading |
Q28280080 | Palmitoylation: policing protein stability and traffic |
Q85584118 | Pancreatic cancer: Targeting KRAS and the vitamin D receptor via microtubules |
Q80146601 | Partial functional overlap of the three ras genes in mouse embryonic development |
Q31106221 | Photoactivatable synthetic Ras proteins: "baits" for the identification of plasma-membrane-bound binding partners of Ras. |
Q42942201 | Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae. |
Q39804200 | Plasma membrane nanoswitches generate high-fidelity Ras signal transduction |
Q38354769 | Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton. |
Q47223139 | Posttranslational Modifications of RAS Proteins. |
Q24291200 | Prenylated Rab acceptor protein is a receptor for prenylated small GTPases |
Q35981331 | Protein palmitoylation inhibition by 2-bromopalmitate alters gliding, host cell invasion and parasite morphology in Toxoplasma gondii |
Q39870883 | Proteomic analysis of protein palmitoylation in adipocytes |
Q39684105 | Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase |
Q56780316 | Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha- RAS -transformed human colon cells |
Q58763445 | RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation |
Q30276654 | Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling |
Q30483788 | Rapid turnover rate of phosphoinositides at the front of migrating MDCK cells |
Q34060983 | Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation |
Q37359986 | Ras acylation, compartmentalization and signaling nanoclusters (Review). |
Q49921459 | Ras and the Plasma Membrane: A Complicated Relationship |
Q93187775 | Ras functional proximity proteomics establishes mTORC2 as new direct ras effector |
Q30404024 | Ras history: The saga continues |
Q34467963 | Ras isoform-specific signaling: location, location, location |
Q29615405 | Ras oncogenes: split personalities |
Q35089365 | Ras pathway signaling on endomembranes |
Q28769530 | Ras plasma membrane signalling platforms |
Q35120159 | Ras proteins: different signals from different locations |
Q36880352 | Ras proteins: paradigms for compartmentalised and isoform-specific signalling. |
Q35062420 | Ras redux: rethinking how and where Ras acts. |
Q42815732 | Ras signalling on the endoplasmic reticulum and the Golgi |
Q36043314 | Ras trafficking, localization and compartmentalized signalling |
Q33351823 | Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events. |
Q34225947 | Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists |
Q34413566 | Ras/MAPK signaling from endomembranes |
Q39724715 | RasGRP1 is essential for ras activation by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in epidermal keratinocytes |
Q37073605 | Rasosomes originate from the Golgi to dispense Ras signals |
Q34051183 | Recent progress in the study of the Rheb family GTPases. |
Q37970568 | Regulating the regulator: post-translational modification of RAS |
Q37096248 | Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains |
Q28293683 | Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10 |
Q34288873 | Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B. |
Q34166819 | Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice |
Q36320940 | Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin. |
Q38559263 | Rheb signaling and tumorigenesis: mTORC1 and new horizons |
Q36416861 | Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A |
Q93241353 | S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi |
Q47144786 | SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a. |
Q40718787 | SNAP-25 traffics to the plasma membrane by a syntaxin-independent mechanism |
Q41152190 | Segregation of negatively charged phospholipids by the polycationic and farnesylated membrane anchor of Kras |
Q30480434 | Signaling-dependent immobilization of acylated proteins in the inner monolayer of the plasma membrane |
Q31062896 | Simultaneous atomic-force and two-photon fluorescence imaging of biological specimens in vivo |
Q42797827 | Single-molecule diffusion reveals similar mobility for the Lck, H-ras, and K-ras membrane anchors |
Q40269415 | Single-molecule imaging of the H-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane |
Q88596873 | Single-shot super-resolution total internal reflection fluorescence microscopy |
Q34076266 | Spatial cycles in G-protein crowd control |
Q37251227 | Spatially selective sampling of single cells using optically trapped fusogenic emulsion droplets: a new single-cell proteomic tool. |
Q34462319 | Specificity of plasma membrane targeting by the rous sarcoma virus gag protein |
Q39249805 | Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. |
Q30528634 | Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms |
Q34342784 | Subcellular localization of the bovine leukemia virus R3 and G4 accessory proteins |
Q40297867 | Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP. |
Q31139475 | Synthesis and application of fluorescent ras proteins for live-cell imaging |
Q57007289 | Synthetic peptide conjugates—tailor-made probes for the biology of protein modification and protein processing |
Q33967144 | Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development |
Q44012141 | The Arabidopsis AtSTE24 is a CAAX protease with broad substrate specificity |
Q33878815 | The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation |
Q41260462 | The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties |
Q38723395 | The G protein-coupled receptor GPR31 promotes membrane association of KRAS. |
Q39426327 | The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins |
Q42828406 | The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras. |
Q49798156 | The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins and their Role in Human Tumorigenesis |
Q41900845 | The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins |
Q90089701 | The balance of protein farnesylation and geranylgeranylation during the progression of nonalcoholic fatty liver disease |
Q37622606 | The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif. |
Q24295264 | The complex of Arl2-GTP and PDE delta: from structure to function |
Q34189442 | The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras |
Q39983039 | The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected |
Q28660742 | The effect of MEP pathway and other inhibitors on the intracellular localization of a plasma membrane-targeted, isoprenylable GFP reporter protein in tobacco BY-2 cells |
Q24540862 | The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes |
Q39007227 | The grab-and-drop protocol: a novel strategy for membrane protein isolation and reconstitution from single cells. |
Q41841993 | The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway |
Q43786808 | The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase |
Q39896125 | The mitogen-activated protein kinase scaffold KSR1 is required for recruitment of extracellular signal-regulated kinase to the immunological synapse |
Q47128365 | The mystery of oncogenic KRAS: Lessons from studying its wild-type counter part |
Q40634841 | The paranodal complex of F3/contactin and caspr/paranodin traffics to the cell surface via a non-conventional pathway. |
Q35566863 | The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences |
Q38077211 | The role of palmitoylation in regulating Ras localization and function. |
Q30375564 | The role of the cytoskeleton in the formation of gap junctions by Connexin 30. |
Q47734724 | The role of toxins in Clostridium difficile infection. |
Q34774553 | The ubiquitin C-terminal hydrolase L1 (UCH-L1) C terminus plays a key role in protein stability, but its farnesylation is not required for membrane association in primary neurons |
Q34575170 | Trafficking and signaling by fatty-acylated and prenylated proteins |
Q35044902 | Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition. |
Q59791944 | UBIAD1 suppresses the proliferation of bladder carcinoma cells by regulating H-Ras intracellular trafficking via interaction with the C-terminal domain of H-Ras |
Q24328791 | USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity |
Q37180578 | VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking |
Q38719156 | Where no Ras has gone before: VPS35 steers N-Ras through the cytosol. |
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