| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0065-2776(08)00005-9 |
| P698 | PubMed publication ID | 18501772 |
| P2093 | author name string | Jürgen Wienands | |
| Niklas Engels | |||
| Michael Engelke | |||
| P2860 | cites work | The strength of receptor signaling is centrally controlled through a cooperative loop between Ca2+ and an oxidant signal. | Q46455045 |
| Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes | Q48164603 | ||
| Ca2+ entry through plasma membrane IP3 receptors. | Q48546959 | ||
| Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement | Q52005570 | ||
| Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory. | Q52014781 | ||
| The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses | Q52043164 | ||
| Effect of transmembrane and cytoplasmic domains of IgE on the IgE response | Q52043166 | ||
| Molecular switches in lipid rafts. | Q55033866 | ||
| Antigen receptor tail clue. | Q55060334 | ||
| Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1 | Q58208013 | ||
| Differential signaling through the Ig-alpha and Ig-beta components of the B cell antigen receptor | Q72074580 | ||
| Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth | Q73177955 | ||
| CD72 negatively regulates signaling through the antigen receptor of B cells | Q73368116 | ||
| Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK | Q73555521 | ||
| Activity of Plasma Membrane-recruited Raf-1 Is Regulated by Ras via the Raf Zinc Finger | Q73555600 | ||
| Src autoinhibition: let us count the ways | Q78062284 | ||
| Dok-3 plays a nonredundant role in negative regulation of B-cell activation | Q79961527 | ||
| Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling | Q81299785 | ||
| The role of RasGRPs in regulation of lymphocyte proliferation | Q82793525 | ||
| Direct visualization of Ras proteins in spatially distinct cell surface microdomains | Q36322914 | ||
| Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage | Q36368736 | ||
| MAPKAP kinases - MKs - two's company, three's a crowd | Q36371939 | ||
| Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor. | Q36401566 | ||
| A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients | Q36402834 | ||
| Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP) | Q36404338 | ||
| MAPK signal specificity: the right place at the right time | Q36444123 | ||
| Membrane and juxtamembrane targeting by PH and PTB domains | Q36522544 | ||
| Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides | Q36557865 | ||
| An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ | Q36564577 | ||
| Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition | Q36601645 | ||
| Functional organization of TRPC-Ca2+ channels and regulation of calcium microdomains | Q36618437 | ||
| Emerging perspectives in store-operated Ca2+ entry: roles of Orai, Stim and TRP. | Q36620941 | ||
| Tonic B-cell and viral ITAM signaling: context is everything. | Q36877363 | ||
| Ca(2+) signaling in antigen receptor-activated B lymphocytes | Q36877372 | ||
| Calcium signalling in lymphocyte activation and disease | Q36912139 | ||
| Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras. | Q37178280 | ||
| Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus. | Q37274925 | ||
| Evidence for a preformed transducer complex organized by the B cell antigen receptor | Q37446227 | ||
| H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway | Q39451813 | ||
| Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling | Q39665762 | ||
| Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1 | Q39790953 | ||
| Biochemical and functional characterization of Orai proteins | Q40172328 | ||
| CRACM1 multimers form the ion-selective pore of the CRAC channel. | Q40231288 | ||
| The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. | Q40381400 | ||
| Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen. | Q40540260 | ||
| Regulation of canonical transient receptor potential (TRPC) channel function by diacylglycerol and protein kinase C. | Q40651352 | ||
| Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells | Q40731238 | ||
| Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. | Q40746067 | ||
| GTP-dependent segregation of H-ras from lipid rafts is required for biological activity | Q40815505 | ||
| Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen | Q40822193 | ||
| Monomeric and oligomeric complexes of the B cell antigen receptor | Q40863334 | ||
| Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk. | Q40987517 | ||
| SHIP Modulates Immune Receptor Responses by Regulating Membrane Association of Btk | Q41042940 | ||
| Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. | Q41063499 | ||
| Antigen Receptor Signaling Gives Lymphocytes a Long Life | Q41607134 | ||
| Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane | Q42414565 | ||
| The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling | Q42462089 | ||
| Identification of anergic B cells within a wild-type repertoire. | Q42505673 | ||
| Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling | Q42798741 | ||
| Novel role of the Ras cascade in memory B cell response. | Q42810996 | ||
| Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling | Q42815571 | ||
| Ras signalling on the endoplasmic reticulum and the Golgi | Q42815732 | ||
| Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function | Q42839859 | ||
| Extracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G. | Q42952003 | ||
| Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol | Q22001504 | ||
| An essential role for BLNK in human B cell development | Q22010875 | ||
| Regulation of the phospholipase C-gamma2 pathway in B cells | Q24290431 | ||
| Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells | Q24296633 | ||
| Human SLP-65 isoforms contribute differently to activation and apoptosis of B lymphocytes | Q24299906 | ||
| Orai1 is an essential pore subunit of the CRAC channel | Q24300383 | ||
| STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx | Q24307461 | ||
| CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry | Q24322017 | ||
| BLNK: a central linker protein in B cell activation | Q24322718 | ||
| Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide | Q24322758 | ||
| SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk | Q24336843 | ||
| STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane | Q24337703 | ||
| Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions | Q24532168 | ||
| The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways | Q24537242 | ||
| Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling | Q24554273 | ||
| Characterization of a novel member of the DOK family that binds and modulates Abl signaling | Q24554382 | ||
| Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation | Q24560019 | ||
| SLP-65: A New Signaling Component in B Lymphocytes which Requires Expression of the Antigen Receptor for Phosphorylation | Q24645697 | ||
| The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival | Q24670427 | ||
| Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum | Q24672652 | ||
| B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1 | Q24675505 | ||
| A novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinase | Q24676484 | ||
| STIM1, an essential and conserved component of store-operated Ca2+ channel function | Q24678317 | ||
| TRP channels and Ca2+ signaling | Q35915824 | ||
| Signaling interplay in Ras superfamily function | Q36211186 | ||
| Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors | Q36229232 | ||
| IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta | Q36229267 | ||
| Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling | Q36301886 | ||
| Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling | Q24678570 | ||
| Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai | Q26793407 | ||
| The Guanine Nucleotide-Binding Switch in Three Dimensions | Q28131710 | ||
| Lipid rafts and signal transduction | Q28131735 | ||
| BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells | Q28137612 | ||
| Interaction of SLP adaptors with the SH2 domain of Tec family kinases | Q28137757 | ||
| Requirement for B cell linker protein (BLNK) in B cell development | Q28139413 | ||
| Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65 | Q28139860 | ||
| Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi | Q28140190 | ||
| CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux | Q28140639 | ||
| GEFs: structural basis for their activation of small GTP-binding proteins | Q28141028 | ||
| SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates | Q28189403 | ||
| Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha | Q28205961 | ||
| Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes | Q28211046 | ||
| CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1 | Q28215970 | ||
| BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins | Q28216264 | ||
| STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels | Q28257477 | ||
| GAP control: regulating the regulators of small GTPases | Q28271241 | ||
| Molecular interactions regulate BCR signal inhibition by CD22 and CD72 | Q28281828 | ||
| Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok | Q28302094 | ||
| A leucine zipper in the N terminus confers membrane association to SLP-65 | Q28302891 | ||
| A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function | Q28305026 | ||
| An acylation cycle regulates localization and activity of palmitoylated Ras isoforms | Q28306968 | ||
| MEK kinase activity is not necessary for Raf-1 function | Q28362229 | ||
| A role for lipid rafts in B cell antigen receptor signaling and antigen targeting | Q28504447 | ||
| Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22 | Q28505152 | ||
| PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling | Q28509628 | ||
| Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling | Q28513972 | ||
| The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain | Q28585554 | ||
| Distinct calcium channels regulate responses of primary B lymphocytes to B cell receptor engagement and mechanical stimuli | Q28589165 | ||
| Targeted disruption ofSHIPleads to hemopoietic perturbations, lung pathology, and a shortened life span | Q28590421 | ||
| Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha | Q28613845 | ||
| Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop | Q28613911 | ||
| RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling | Q28614295 | ||
| Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation | Q28615635 | ||
| Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1 | Q28646373 | ||
| Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif | Q28910404 | ||
| The versatility and universality of calcium signalling | Q29547402 | ||
| Coordinating ERK/MAPK signalling through scaffolds and inhibitors | Q29618995 | ||
| The RAF proteins take centre stage | Q29620153 | ||
| Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src. | Q30175215 | ||
| A requirement for lipid rafts in B cell receptor induced Ca(2+) flux | Q30305546 | ||
| The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions | Q30480480 | ||
| Regulation of RasGRP via a phorbol ester-responsive C1 domain. | Q31973953 | ||
| Understanding Ras: 'it ain't over 'til it's over'. | Q33877218 | ||
| Control of B cell development by Ras-mediated activation of Raf. | Q33887809 | ||
| Structural determinants of Ras-Raf interaction analyzed in live cells | Q33893597 | ||
| Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling | Q34038099 | ||
| Surface chimeric receptors as tools in study of lymphocyte activation | Q34068031 | ||
| Positive and negative regulation of Raf kinase activity and function by phosphorylation | Q34080535 | ||
| An inositol 1,4,5-trisphosphate receptor-dependent cation entry pathway in DT40 B lymphocytes | Q34091197 | ||
| Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3 | Q34194640 | ||
| Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. | Q34293814 | ||
| Oligomeric antigen receptors: a new view on signaling for the selection of lymphocytes | Q34295050 | ||
| The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization | Q34360396 | ||
| Antigen receptors on B lymphocytes | Q34420640 | ||
| BLNK mediates Syk-dependent Btk activation | Q34476463 | ||
| Negative regulation of immunoreceptor signaling | Q34542282 | ||
| The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer | Q34561465 | ||
| PIP(2) and proteins: interactions, organization, and information flow | Q34623576 | ||
| The B-cell antigen receptor of the five immunoglobulin classes | Q34835910 | ||
| The alpha/beta sheath and its cytoplasmic tyrosines are required for signaling by the B-cell antigen receptor but not for capping or for serine/threonine-kinase recruitment | Q34977999 | ||
| Hydrogen peroxide as second messenger in lymphocyte activation | Q35007083 | ||
| The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells | Q35081009 | ||
| Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha | Q35224448 | ||
| Orai proteins interact with TRPC channels and confer responsiveness to store depletion. | Q35721728 | ||
| Native TRPC7 channel activation by an inositol trisphosphate receptor-dependent mechanism | Q35741646 | ||
| Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes | Q35834585 | ||
| P921 | main subject | B-cell | Q188930 |
| P304 | page(s) | 251-281 | |
| P577 | publication date | 2008-01-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Advances in Immunology | Q15752932 |
| P1476 | title | Conformational plasticity and navigation of signaling proteins in antigen-activated B lymphocytes | |
| P478 | volume | 97 |
| Q33863904 | Complex phosphorylation dynamics control the composition of the Syk interactome in B cells |
| Q64252868 | Differential organization of tonic and chronic B cell antigen receptors in the plasma membrane |
| Q54618008 | Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells |
| Q37672405 | Inositol trisphosphate 3-kinases: focus on immune and neuronal signaling |
| Q41616016 | NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells |
| Q40704473 | Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement |
| Q34623132 | Oligomeric organization of the B-cell antigen receptor on resting cells |
| Q24319764 | The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85 |
| Q30009963 | The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters |
| Q37572324 | The cytoplasmic domain of the T-cell receptor zeta subunit does not form disordered dimers |
| Q37797618 | The dissociation activation model of B cell antigen receptor triggering |
| Q37842920 | The signaling tool box for tyrosine-based costimulation of lymphocytes |
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