Extracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G.

scientific article published on 4 December 2006

Extracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.01530-06
P932PMC publication ID1800707
P698PubMed publication ID17145771
P5875ResearchGate publication ID6652894

P2093author name stringMasaki Hikida
Tomohiro Kurosaki
Naoya Hatano
Masato Ogata
Yoshiko Mori
Yuichi Aiba
Hideki Sanjo
P2860cites workIdentification and Characterization of a Novel Protein Interacting with Ral-binding Protein 1, a Putative Effector Protein of RalQ24318512
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BCMA is essential for the survival of long-lived bone marrow plasma cellsQ28587037
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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
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Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascadeQ31929689
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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populationsQ34885732
Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytesQ35834585
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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centersQ36231790
Follicular B helper T cells in antibody responses and autoimmunity.Q36302329
Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stageQ36368736
Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survivalQ36368882
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cellsQ36371743
Quantitation of immunoglobulin mu-gamma 1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction methodQ37130407
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune diseaseQ37600558
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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.Q40626751
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.Q40662652
Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigenQ40822193
Clonal selection and learning in the antibody systemQ41002744
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The changing preference of T and B cells for partners as T-dependent antibody responses developQ41492213
How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis.Q41721329
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.Q42800979
Novel role of the Ras cascade in memory B cell response.Q42810996
Coupling between B cell receptor and phospholipase C-gamma2 is essential for mature B cell developmentQ42945151
Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigensQ43603650
A distinct signaling pathway used by the IgG-containing B cell antigen receptorQ44257389
CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centersQ45299573
Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.Q45965344
The role of erk1 and erk2 in multiple stages of T cell developmentQ50954940
Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory.Q52014781
Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signalingQ73378299
Pre-B Cell Receptor Signaling Mediates Selective Response to IL-7 at the Pro-B to Pre-B Cell Transition via an ERK/MAP Kinase-Dependent PathwayQ74840030
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1236-1246
P577publication date2006-12-04
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleExtracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G.
P478volume27

Reverse relations

cites work (P2860)
Q37172538Conformational plasticity and navigation of signaling proteins in antigen-activated B lymphocytes
Q51012088ERKs Induce Expression of the Transcriptional Repressor Blimp-1 and Subsequent Plasma Cell Differentiation
Q54659689Enhanced T cell-independent antibody responses in c-Jun N-terminal kinase 2 (JNK2)-deficient B cells following stimulation with CpG-1826 and anti-IgM
Q54122098Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells
Q35047271Mitogen‐activated protein kinase signalling and ERK1/2 bistability in asthma
Q30390170Molecular characterization of in vivo adjuvant activity in ferrets vaccinated against influenza virus
Q54770022Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.
Q37234308PLC-gamma2 is essential for formation and maintenance of memory B cells
Q39975996RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo
Q42562424Raf-independent, PP2A-dependent MEK activation in response to ERK silencing
Q36421040Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

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