In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations is …
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scholarly articleQ13442814

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P356DOI10.1084/JEM.173.5.1165
P932PMC publication ID2118845
P698PubMed publication ID1902502
P5875ResearchGate publication ID246561851

P2093author name stringJ Jacob
G Kelsoe
R Kassir
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Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequencesQ36353825
Inter- and intraclonal diversity in the antibody response to influenza hemagglutininQ36355399
Early onset of somatic mutation in immunoglobulin VH genes during the primary immune responseQ36356525
Growth of B-lymphocyte colonies in vitroQ36358857
Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable regionQ36630020
Direct intrafollicular differentiation of memory B cells into plasma cellsQ37922204
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Analysis of the repertoire of anti-(4-hydroxy-3-nitro-phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti-idiotope antibodiesQ41196929
Idiotypic analysis of the response of C57BL/6 mice to the (4-hydroxy-3-nitrophenyl)acetyl groupQ41314640
Murine V kappa gene expression does not follow the VH paradigmQ41819022
Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NPQ42573237
Antibody engineering for the analysis of affinity maturation of an anti-hapten response.Q42735546
Mapping of antibody specificities to VH gene familiesQ42800441
Strain-dependent expression of VH gene familiesQ42800571
VH-gene expression in murine lipopolysaccharide blasts distributes over the nine known VH-gene groups and may be randomQ44171947
Synthesis of antibody and immunoglobulins without detectable antibody function in cells responding to horseradish peroxidaseQ44523695
Development of B cell lineages during a primary anti-hapten immune responseQ48248175
A limited number of B cell lineages generates the heterogeneity of a secondary immune response.Q48333272
Somatic variants of murine immunoglobulin λ light chainsQ48403814
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genesQ48412817
Correlations between immunoglobulin- and antibody-synthesizing cells during primary and secondary immune responses of rats immunized with peroxidaseQ52242692
Peanut lectin binding properties of germinal centres of mouse lymphoid tissue.Q52851284
Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cellsQ53549666
Detection of antibody, idiotype, and anti-idiotype forming cells by in situ immunocytochemical stainingQ53803593
Strain differences in the fine specificity of mouse antihapten antibodiesQ54115136
Antigen-binding repertoire and Ig H chain gene usage among B cell hybridomas from normal and autoimmune miceQ67273728
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell coloniesQ68836283
Monoclonal anti-allotype antibody towards BALB/c IgM. Analysis of specificity and site of a V-C crossover in recombinant strain BALB-Igh-Va/Igh-CbQ69021421
Comparison of V kappa gene family expression in adult and fetal B cellsQ69236908
Primary in situ immune response in popliteal lymph nodes and spleen of mice after subcutaneous immunization with thymus-dependent or thymus-independent (type 1 and 2) antigensQ69595249
The de novo generation of germinal centers is an oligoclonal processQ70266774
The anatomy of peripheral lymphoid organs with emphasis on accessory cells: light-microscopic immunocytochemical studies of mouse spleen, lymph node, and Peyer's patchQ70606407
The development of specific antibody-containing cells in the spleen of rabbits during the secondary immune response against free or liposome-associated albumin antigenQ71009730
Antibody with homogeneous antigen binding produced by splenic foci in organ cultureQ71220293
CELL PROLIFERATION IN GERMINAL CENTERS OF THE RAT SPLEENQ76721614
THE WHITE PULP OF THE SPLEEN. THE RELATIONSHIPS OF ARTERIAL VESSELS, RETICULUM AND FREE CELLS IN THE PERIARTERIAL LYMPHATIC SHEATHQ76938409
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1165-1175
P577publication date1991-05-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleIn situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations
P478volume173

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Q36478485SWAP-70 deficiency causes high-affinity plasma cell generation despite impaired germinal center formation
Q54979506SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production.
Q47876829Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival
Q24536218Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease
Q40373293Self-tolerance checkpoints in B lymphocyte development
Q37156660Sequencing heavy- and light-chain variable genes of single B-hybridoma cells by total enzymatic amplification
Q71420926Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c
Q28585021Severe attenuation of the B cell immune response in Msh2-deficient mice
Q39737614Short-circuiting long-lived humoral immunity by the heightened engagement of CD40.
Q41492235Signaling thresholds and interclonal competition in preimmune B-cell selection
Q37132162Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity
Q33959225Silent development of memory progenitor B cells
Q41602537Sites of B lymphocyte selection, activation, and tolerance in spleen
Q43603650Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
Q52053087Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.
Q41222940Somatic diversification of antibody responses
Q47110972Spoiling for a Fight: B Lymphocytes As Initiator and Effector Populations within Tertiary Lymphoid Organs in Autoimmunity and Transplantation.
Q36400509Spontaneous follicular exclusion of SHP1-deficient B cells is conditional on the presence of competitor wild-type B cells
Q57897255Stochastic discrete event simulation of germinal center reactions
Q34242639Studies of the humoral immune response
Q35321772Surface markers, heavy chain sequences and B cell lineages
Q38002491T cells that promote B-Cell maturation in systemic autoimmunity
Q36400665T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching
Q36367277T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1.
Q40527478Targeting and regulation of immunoglobulin gene somatic hypermutation and isotype switch recombination
Q41876688The B cell receptor itself can activate complement to provide the complement receptor 1/2 ligand required to enhance B cell immune responses in vivo
Q35796008The Emu-bcl-2 transgene enhances antigen-induced germinal center formation in both BALB/c and SJL mice but causes age-dependent germinal center hyperplasia only in the lymphoma-prone SJL strain
Q48011135The Fas antigen and Fas-mediated apoptosis in B-cell differentiation
Q50349777The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production.
Q36365985The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response
Q37688958The anatomy of T-cell activation and tolerance
Q41492213The changing preference of T and B cells for partners as T-dependent antibody responses develop
Q36171758The development of B cells and the B-cell repertoire in the microenvironment of the germinal center
Q35380833The dynamics of T cell-dependent B cell responses in vivo
Q37784588The elusive identity of T follicular helper cells
Q38070792The establishment of the plasma cell survival niche in the bone marrow
Q33886727The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response
Q41937356The extent of clonal structure in different lymphoid organs
Q36366646The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.
Q79435564The germinal center response is impaired in the absence of T cell-expressed CXCR5
Q33922881The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation.
Q56904544The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells
Q35307418The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation
Q52170468The origin of anti-nuclear antibodies in bcl-2 transgenic mice.
Q36171744The path of memory B-cell development
Q71047935The phenotype and fate of the antibody-forming cells of the splenic foci
Q41492250The physiology of murine germinal center reactions
Q36079896The regulation and activation of lupus-associated B cells
Q34033732The road to the production of IgE is long and winding
Q47933342The role of germinal centers for antiviral B cell responses
Q52039310The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment.
Q35981133The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.
Q34311595The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival
Q41472333To 'B' or not to 'B' a germinal center?
Q37374679Toll-like receptor 3 ligand and retinoic acid enhance germinal center formation and increase the tetanus toxoid vaccine response
Q79818179Toll-like receptor engagement stimulates anti-snRNP autoreactive B cells for activation
Q40874465Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
Q36366754Tracing the development of single memory-lineage B cells in a highly defined immune response
Q50559773Trypanosoma cruzi infection induces a massive extrafollicular and follicular splenic B-cell response which is a high source of non-parasite-specific antibodies.
Q33592023Tumor necrosis factor alpha p55 receptor is important for development of memory responses to blood-stage malaria infection
Q48509911Twenty-five years of germinal centre physiology: implications for tolerance in the secondary B cell repertoire
Q33979882Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response
Q41492243Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice
Q58591219Unresponsiveness following immunization with the T-cell-independent antigen dextran B512. Can it be abrogated?
Q36370154Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced
Q36376518Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production
Q36404575Virus-induced maturation and activation of autoreactive memory B cells
Q36370951Visualization of the genesis and fate of isotype-switched B cells during a primary immune response
Q37078589Visualizing antibody affinity maturation in germinal centers
Q29616233Visualizing dendritic cell networks in vivo
Q37212132Vitamin A and retinoic acid in the regulation of B-cell development and antibody production
Q41224472Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation
Q37395797mTOR has distinct functions in generating versus sustaining humoral immunity.

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