The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.

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The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.183.5.2313
P932PMC publication ID2192557
P698PubMed publication ID8642340

P50authorAlan LyonsQ59678759
P2093author name stringA Basten
C Parish
M C Cook
D A Fulcher
C Koleda
B Fazekas de St Groth
S L Korn
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In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactionsQ36362569
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Cross-linking of membrane immunoglobulin D, in the absence of T cell help, kills mature B cells in vivoQ36364373
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The requirement of more than one antigenic determinant for immunogenicityQ41822375
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-toleranceQ41888015
B cell diversification and differentiation in the peripheryQ42175508
Allotypic specificities of murine IgD and IgM recognized by monoclonal antibodies.Q42798735
Major histocompatibility complex-restricted, polyclonal B cell responses resulting from helper T cell recognition of antiimmunoglobulin presented by small B lymphocytesQ42937260
Reduced life span of anergic self-reactive B cells in a double-transgenic modelQ42942098
Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cellsQ42942148
Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE.Q43466038
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Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigensQ43603650
Immunological prediction of sequence differences among proteins. Chemical comparison of chicken, quail, and phesant lysozymesQ44664735
Virus or a hapten-carrier complex can activate autoreactive B cells by providing linked T help.Q45783315
Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.Q46109491
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The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation.Q51023960
Tolerance susceptibility of newly generating memory B cells.Q52097861
Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.Q52227004
The carrier effect in the secondary response to hapten‐protein conjugates. IV. Uptake of antigen in vitro and failure to obtain cooperative induction in vitroQ52260898
Induction of self-tolerance in mature peripheral B lymphocytesQ59057608
Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cellsQ59061491
Expression of anti-DNA immunoglobulin transgenes in non-autoimmune miceQ59065295
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genesQ59098044
Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic miceQ68192458
Monoclonal anti-allotype antibody towards BALB/c IgM. Analysis of specificity and site of a V-C crossover in recombinant strain BALB-Igh-Va/Igh-CbQ69021421
Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40Q71616325
Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell developmentQ72120139
IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complementQ72620771
Mapping the antigenic epitope for a monoclonal antibody against lysozymeQ72654589
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)2313-2328
P577publication date1996-05-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleThe fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help
P478volume183

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