Humoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell

scientific article published on 29 January 2015

Humoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.AAA1342
P932PMC publication ID4412594
P698PubMed publication ID25636798

P50authorMarc K. JenkinsQ38326121
Holly R SteachQ57321360
P2093author name stringJustin J Taylor
Kathryn A Pape
P2860cites workProapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunityQ28138855
Determination of lymphocyte division by flow cytometryQ28253058
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor.Q30437109
A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal centerQ35213561
A germinal center-independent pathway generates unswitched memory B cells early in the primary responseQ35825984
Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiationQ36228608
The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.Q36366646
Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.Q36641930
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4Q36949425
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.Q37155667
Environmental cues dictate the fate of individual CD8+ T cells responding to infectionQ37280053
Different B cell populations mediate early and late memory during an endogenous immune responseQ37712769
Determining germinal centre B cell fate.Q38010907
Heterogeneity in the differentiation and function of memory B cellsQ38037738
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.Q41423746
Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturationQ43819902
Disparate individual fates compose robust CD8+ T cell immunityQ44525218
Heterogeneous differentiation patterns of individual CD8+ T cells.Q44758058
Visualization of specific B and T lymphocyte interactions in the lymph nodeQ47892330
Activation-induced B cell fates are selected by intracellular stochastic competition.Q53193895
Experimental analysis by site-directed mutagenesis of somatic mutation effects on affinity and fine specificity in antibodies specific for lysozymeQ67723990
P433issue6223
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
P304page(s)784-787
P577publication date2015-01-29
P1433published inScienceQ192864
P1476titleHumoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell
P478volume347

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cites work (P2860)
Q52582170Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.
Q98302868Antibody-secreting cell destiny emerges during the initial stages of B-cell activation
Q48131419Atypical chemokine receptor 4 shapes activated B cell fate.
Q40101373B Cell Tetramer Development for Veterinary Vaccinology
Q54940202B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
Q59349637Basics of memory B-cell responses: lessons from and for the real world
Q39576940Biologics to treat substance use disorders: Current status and new directions
Q37276771CD301b+ dendritic cells suppress T follicular helper cells and antibody responses to protein antigens
Q37549756CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions.
Q33778888Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans
Q92184345Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes
Q90479592FB5P-seq: FACS-Based 5-Prime End Single-Cell RNA-seq for Integrative Analysis of Transcriptome and Antigen Receptor Repertoire in B and T Cells
Q38960786Germinal Center B Cell Dynamics
Q47759018ICAMs support B cell interactions with T follicular helper cells and promote clonal selection.
Q47108872IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repression.
Q36818340Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory
Q90167856Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine
Q33426736N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.
Q37504890Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation
Q59138110Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses
Q92203848Programming Isotype-Specific Plasma Cell Function
Q42051356Rabies virus lipopeptide conjugated to a TLR7 agonist improves the magnitude and quality of the Th1-biased humoral immune response in mice.
Q58552434Regulation of metabolic supply and demand during B cell activation and subsequent differentiation
Q92147757Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease
Q47110972Spoiling for a Fight: B Lymphocytes As Initiator and Effector Populations within Tertiary Lymphoid Organs in Autoimmunity and Transplantation.
Q47108542Structural basis of antigen recognition: crystal structure of duck egg lysozyme
Q39108730Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem
Q37549732The aryl hydrocarbon receptor controls cell-fate decisions in B cells.
Q36278801The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence.
Q47315100The strength of BCR signaling shapes terminal development of follicular helper T cells in mice
Q38583565Transcription factors regulating B cell fate in the germinal centre.
Q100465086Transcriptional regulation of memory B cell differentiation
Q62002175Whatever will B cell be?
Q58804243When designing vaccines, consider the starting material: the human B cell repertoire

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