Rabies virus lipopeptide conjugated to a TLR7 agonist improves the magnitude and quality of the Th1-biased humoral immune response in mice.

scientific article published on 20 July 2016

Rabies virus lipopeptide conjugated to a TLR7 agonist improves the magnitude and quality of the Th1-biased humoral immune response in mice. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2016.06.019
P698PubMed publication ID27449478

P50authorInam Ullah KhanQ84060205
P2093author name stringRui Liu
Yan Yang
Jingbo Wang
Naishuo Zhu
P2860cites workEstimating the global burden of endemic canine rabiesQ21090117
Antigen presentation and T cell stimulation by dendritic cellsQ22255632
Toll-like receptors in antiviral innate immunityQ27011462
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-betaQ28506630
Programming the magnitude and persistence of antibody responses with innate immunityQ30400144
TLR7 recognition is dispensable for influenza virus A infection but important for the induction of hemagglutinin-specific antibodies in response to the 2009 pandemic split vaccine in miceQ30419734
Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signalingQ33641422
Characterization of a single-cycle rabies virus-based vaccine vectorQ33676502
Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in miceQ34038100
Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivationQ34059398
Synthesis and immunological characterization of toll-like receptor 7 agonistic conjugatesQ34291783
Expression of interferon gamma by a recombinant rabies virus strongly attenuates the pathogenicity of the virus via induction of type I interferon.Q34992598
The TLR7 agonist induces tumor regression both by promoting CD4⁺T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cellsQ35176439
Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell-Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype DiversificationQ35823060
A TLR9 agonist enhances the anti-tumor immunity of peptide and lipopeptide vaccines via different mechanismsQ35895400
rIL-22 as an adjuvant enhances the immunogenicity of rGroEL in mice and its protective efficacy against S. Typhi and S. TyphimuriumQ36302839
Toll-like receptor 7 mediates early innate immune responses to malariaQ37336051
Toll-like receptor 7 agonist imiquimod in combination with influenza vaccine expedites and augments humoral immune responses against influenza A(H1N1)pdm09 virus infection in BALB/c mice.Q37712843
The immune response to rabies virus infection and vaccinationQ37724483
The role of toll-like receptors in the induction of immune responses during rabies virus infection.Q37877955
Innate antiviral signalling in the central nervous systemQ38169444
Toll-like receptor signaling pathwaysQ38259564
siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo.Q39572943
A novel rabies virus lipopeptide provides a better protection by improving the magnitude of DCs activation and T cell responses.Q39764413
Humoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cellQ40019887
Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3.Q40416432
A rabies vaccine adjuvanted with saponins from leaves of the soap tree (Quillaja brasiliensis) induces specific immune responses and protects against lethal challengeQ40824269
Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to PolysaccharidesQ41099515
Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypesQ45184856
A CpG oligodeoxynucleotide acts as a potent adjuvant for inactivated rabies virus vaccineQ45396680
The history of Toll-like receptors - redefining innate immunity.Q46240771
Liposomes containing NY‑ESO‑1/tetanus toxoid and adjuvant peptides targeted to human dendritic cells via the Fc receptor for cancer vaccines.Q51075893
Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.Q51991421
Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells.Q54689085
TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responsesQ79717981
TLR9 signaling in B cells determines class switch recombination to IgG2aQ79718037
TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturationQ83226449
TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surfaceQ85831264
P407language of work or nameEnglishQ1860
P921main subjectrabiesQ39222
toll-like receptorQ408004
rabies virusQ698976
P1104number of pages9
P304page(s)102-110
P577publication date2016-07-21
P1433published inVirologyQ7934867
P1476titleRabies virus lipopeptide conjugated to a TLR7 agonist improves the magnitude and quality of the Th1-biased humoral immune response in mice
P478volume497

Reverse relations

cites work (P2860)
Q40086752Addition of a TLR7 agonist to an acellular pertussis vaccine enhances Th1 and Th17 responses and protective immunity in a mouse model
Q91808429Monophosphoryl-Lipid A (MPLA) is an Efficacious Adjuvant for Inactivated Rabies Vaccines
Q64114489Toll-Like Receptor 7 Enhances Rabies Virus-Induced Humoral Immunity by Facilitating the Formation of Germinal Centers

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