Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

scientific article

Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID2120668

P2093author name stringAraki S
Ueda T
Hori Y
Fujioka H
Fukumoto Y
Takai Y
Kikuchi A
Kaibuchi K
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)1321-1328
P577publication date1990-09-01
P1433published inOncogeneQ1568657
P1476titleMolecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins
P478volume5

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cites work (P2860)
Q36658796A Drosophila homolog of bovine smg p25a GDP dissociation inhibitor undergoes a shift in isoelectric point in the developmental mutant quartet
Q24564664A novel role for RhoGDI as an inhibitor of GAP proteins
Q83226303A proteomic investigation into adriamycin chemo-resistance of human leukemia K562 cells
Q37555518A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.
Q41963968ADP-ribosylation of Rho proteins by Clostridium botulinum exoenzyme C3 is influenced by phosphorylation of Rho-associated factors
Q36764175ARHGDIA: a novel gene implicated in nephrotic syndrome
Q42369182Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα.
Q42058326Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.
Q40615070An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells
Q37718354Blocking hepatic metastases of colon cancer cells using an shRNA against Rac1 delivered by activatable cell-penetrating peptide
Q41976275C-terminal di-arginine motif of Cdc42 protein is essential for binding to phosphatidylinositol 4,5-bisphosphate-containing membranes and inducing cellular transformation
Q27939243Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity
Q36028928Cell polarization and cytokinesis in budding yeast
Q35740897Central roles of small GTPases in the development of cell polarity in yeast and beyond
Q40616444Clostridial ADP-ribosylating toxins: effects on ATP and GTP-binding proteins
Q24522454Clostridium difficile toxins: mechanism of action and role in disease
Q37441470Concordance and interaction of guanine nucleotide dissociation inhibitor (RhoGDI) with RhoA in oogenesis and early development of the sea urchin
Q34002797Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a gln residue in the conserved G-3 domain of the rho family and preferentially inhibits the GTPase activity of RhoA and rac1
Q28576213DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1
Q39509496Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: activation of c-Jun N-terminal kinase in HeLa cells.
Q39647962Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI.
Q24674800Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding
Q24291941Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF
Q35001873Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements
Q40013316Downregulation of Rho-GDI gamma promotes differentiation of neural stem cells
Q47616516EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1.
Q33477862Expression of Rho GDIalpha in rat osteoblasts intermittently exposed to parathyroid hormone in vitro and in vivo
Q28506649FERM domain containing protein 7 interacts with the Rho GDP dissociation inhibitor and specifically activates Rac1 signaling
Q27936269GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization
Q64913711Generation of GLA-Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy.
Q33278299Genes and proteins differentially expressed during in vitro malignant transformation of bovine pancreatic duct cells
Q27931888Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.
Q39451813H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
Q30305468Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes
Q35833162Hypoxia/reoxygenation-experienced cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of thymosin beta-4.
Q36188915Immunological and Functional Characterization of RhoGDI3 and Its Molecular Targets RhoG and RhoB in Human Pancreatic Cancerous and Normal Cells
Q33633239Influence of ARHGEF3 and RHOA knockdown on ACTA2 and other genes in osteoblasts and osteoclasts
Q37872833Interplay between FAK, PKCδ, and p190RhoGAP in the regulation of endothelial barrier function
Q24642838Intracellular localization of the P21rho proteins
Q36658331Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility
Q24303851Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export
Q37212922Localization and translocation of RhoA protein in the human gastric cancer cell line SGC-7901.
Q37277822Loss of RhoGDI is a novel independent prognostic factor in hepatocellular carcinoma
Q24311993Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes
Q33385565Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein
Q39797677Morphological and proliferative abnormalities in renal mesangial cells lacking RhoGDI.
Q38335801Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity
Q38306703N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization
Q37358214New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes
Q70137105New nucleotide sequence data on the EMBL File Server
Q28344277Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes
Q30417648Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells.
Q41063804Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
Q95825676ROM7/BEM4 encodes a novel protein that interacts with the Rho1p small GTP-binding protein in Saccharomyces cerevisiae
Q36677635Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin
Q30176086Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain
Q24658227Ras-related GTPases and the cytoskeleton
Q24671083Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
Q36233026Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).
Q43203082Rho GDP dissociation inhibitor-mediated disruption of Rho GTPase activity impairs lens fiber cell migration, elongation and survival
Q47096248Rho GDP dissociation inhibitor-β in renal cell carcinoma
Q33873342Rho GDP-dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer
Q41078708Rho guanine nucleotide dissociation inhibitor protein (RhoGDI) inhibits exocytosis in mast cells
Q37369834Rho proteins play a critical role in cell migration during the early phase of mucosal restitution
Q37401139Rho signaling mediates cytoskeletal re-arrangements in octopus photoreceptors
Q29614250Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
Q36899158Rho5p is involved in mediating the osmotic stress response in Saccharomyces cerevisiae, and its activity is regulated via Msi1p and Npr1p by phosphorylation and ubiquitination
Q37122746RhoGDIbeta-induced hypertrophic growth in H9c2 cells is negatively regulated by ZAK.
Q24314694RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
Q34317487Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption
Q30194274Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase
Q27931356Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae
Q24294818Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase
Q28118705Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling
Q33931717Signaling from Ras to Rac and beyond: not just a matter of GEFs
Q38166254Small Rho GTPases in the control of cell shape and mobility
Q24533367Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1.
Q39836728TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases
Q24606819The 'invisible hand': regulation of RHO GTPases by RHOGDIs
Q35973755The GTP-binding protein RhoA mediates Na,K-ATPase exocytosis in alveolar epithelial cells
Q40733281The Ras signal transduction pathway
Q29614253The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
Q39574637The Rho family G proteins play a critical role in muscle differentiation
Q27940101The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae
Q24562382The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile
Q34415897The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria
Q30503973WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
Q24321379cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins
Q59100526p104 binds to Rac1 and reduces its activity during myotube differentiation of C2C12 cell
Q34069975p125A exists as part of the mammalian Sec13/Sec31 COPII subcomplex to facilitate ER-Golgi transport
Q36649998rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells

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