| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0006-291X(03)00615-6 |
| P953 | full work available at URL | https://api.elsevier.com/content/article/PII:S0006291X03006156?httpAccept=text/plain |
| https://api.elsevier.com/content/article/PII:S0006291X03006156?httpAccept=text/xml | ||
| P698 | PubMed publication ID | 12729577 |
| P5875 | ResearchGate publication ID | 10774861 |
| P50 | author | Stanley J. Korsmeyer | Q138795 |
| Luca Scorrano | Q16854174 | ||
| P2860 | cites work | Genes & Development | Q1524533 |
| Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria | Q22008484 | ||
| Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC | Q22009974 | ||
| Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria | Q22011013 | ||
| Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis | Q24291662 | ||
| Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors | Q24310559 | ||
| Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 | ||
| Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death | Q24311298 | ||
| X-linked IAP is a direct inhibitor of cell-death proteases | Q24318710 | ||
| Bim: a novel member of the Bcl-2 family that promotes apoptosis | Q24532974 | ||
| IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases | Q24533214 | ||
| Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis | Q24533270 | ||
| Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity | Q24680994 | ||
| A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast | Q24685400 | ||
| Structure of Bax: coregulation of dimer formation and intracellular localization | Q27628839 | ||
| The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria | Q27938333 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
| Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim | Q28214708 | ||
| BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity | Q28249553 | ||
| Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis | Q28283313 | ||
| Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL. | Q40024055 | ||
| Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence | Q40137371 | ||
| Bid acts on the permeability transition pore complex to induce apoptosis | Q40827697 | ||
| Mitochondrial ultracondensation, but not swelling, is involved in TNF alpha-induced apoptosis in human T-lymphoblastic leukaemic cells. | Q41076130 | ||
| Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line | Q41098628 | ||
| The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant | Q41723645 | ||
| Injected cytochrome c induces apoptosis | Q42832504 | ||
| Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes | Q43508166 | ||
| Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells | Q43514949 | ||
| Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax. | Q43551075 | ||
| The apoptotic protein tBid promotes leakage by altering membrane curvature | Q44039942 | ||
| Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. | Q44224227 | ||
| The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria. | Q44810762 | ||
| Ultrastructural localization of cytochrome c in apoptosis demonstrates mitochondrial heterogeneity. | Q49078003 | ||
| Quantitative cytochemistry of the diaminobenzidine cytochrome oxidase reaction product in mitochondria of cardiac muscle and pancreas | Q52433623 | ||
| Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel. | Q52518634 | ||
| A thermodynamic model describing the nature of the crista junction: a structural motif in the mitochondrion. | Q53674378 | ||
| Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals. | Q53967833 | ||
| Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells | Q58885458 | ||
| Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore | Q73107174 | ||
| Cytochrome c release from mitochondria: all or nothing | Q73521425 | ||
| The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition | Q74358996 | ||
| Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange | Q74607067 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Apaf1 is required for mitochondrial pathways of apoptosis and brain development | Q28505574 | ||
| Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis | Q28509136 | ||
| Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis | Q28511080 | ||
| The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues | Q28512628 | ||
| Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis | Q28512752 | ||
| Cytochrome c release from mitochondria proceeds by a two-step process | Q28571562 | ||
| Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death | Q28586301 | ||
| Bax directly induces release of cytochrome c from isolated mitochondria | Q28588847 | ||
| Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane | Q28647586 | ||
| Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis | Q28647600 | ||
| Mitochondria and apoptosis | Q29547905 | ||
| BCL-2 family members and the mitochondria in apoptosis | Q29614427 | ||
| Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane | Q29616354 | ||
| The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis | Q29616568 | ||
| Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 | Q29618617 | ||
| Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation | Q29620223 | ||
| BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis | Q29620466 | ||
| Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics | Q29620467 | ||
| A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis | Q29620536 | ||
| The machinery of mitochondrial inheritance and behavior | Q33538526 | ||
| Mitochondrial transport of cations: channels, exchangers, and permeability transition. | Q33744633 | ||
| Endogenous inhibitors of caspases | Q33816829 | ||
| Organelle division: Self-assembling GTPase caught in the middle | Q33912827 | ||
| BAX-dependent transport of cytochrome c reconstituted in pure liposomes | Q33912996 | ||
| The internal structure of mitochondria | Q33953227 | ||
| Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity. | Q34012615 | ||
| Imaging the permeability pore transition in single mitochondria | Q34167671 | ||
| Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice | Q34408475 | ||
| Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications. | Q34499144 | ||
| A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c. | Q34582647 | ||
| BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak | Q35079498 | ||
| Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions | Q36255553 | ||
| The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol | Q36301514 | ||
| Intrinsic curvature hypothesis for biomembrane lipid composition: a role for nonbilayer lipids | Q37689757 | ||
| The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L). | Q39447996 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | biochemistry | Q7094 |
| biophysics | Q7100 | ||
| cell biology | Q7141 | ||
| P304 | page(s) | 437-444 | |
| P577 | publication date | 2003-05-01 | |
| 2003-05-09 | |||
| P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
| P1476 | title | Mechanisms of cytochrome c release by proapoptotic BCL-2 family members | |
| P478 | volume | 304 |
| Q36547042 | (De)constructing mitochondria: what for? |
| Q38788378 | 3,6-Diazaphenothiazines as potential lead molecules - synthesis, characterization and anticancer activity |
| Q35743650 | A comparison of the biological effects of 125I seeds continuous low-dose-rate radiation and 60Co high-dose-rate gamma radiation on non-small cell lung cancer cells |
| Q34623508 | A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis |
| Q36897072 | A mechanistic view of mitochondrial death decision pores. |
| Q36890525 | A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor κB (NFκB)-mediated cardiac transcription. |
| Q52903434 | A polysaccharide from pumpkin induces apoptosis of HepG2 cells by activation of mitochondrial pathway. |
| Q46952536 | A role of cell apoptosis in lipopolysaccharide (LPS)-induced nonlethal liver injury in D-galactosamine (D-GalN)-sensitized rats |
| Q40625961 | AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis |
| Q44800956 | Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis |
| Q39007027 | Actinidia callosa peel (kiwi fruit) ethanol extracts protected neural cells apoptosis induced by methylglyoxal through Nrf2 activation |
| Q46842793 | Activation of apoptotic processes during transition from hypertrophy to heart failure in guinea pigs. |
| Q39714162 | Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. |
| Q40581766 | Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases |
| Q28536827 | Alpha cyano-4-hydroxy-3-methoxycinnamic acid inhibits proliferation and induces apoptosis in human breast cancer cells |
| Q40145507 | Alpha1,3 Fucosyltransferase-VII modifies the susceptibility of apoptosis induced by ultraviolet and retinoic acid in human hepatocarcinoma cells |
| Q33731197 | Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation |
| Q50077375 | An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis. |
| Q24630079 | An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship |
| Q42293234 | Anti-Aging Effect of Nigella Sativa Fixed Oil on D-Galactose-Induced Aging in Mice |
| Q37684824 | Anti-apoptotic genes in the survival of monocytic cells during infection |
| Q37297695 | Antiapoptotic Effect of Paricalcitol in Gentamicin-induced Kidney Injury |
| Q46861478 | Anticancer effect of calycopterin via PI3K/Akt and MAPK signaling pathways, ROS-mediated pathway and mitochondrial dysfunction in hepatoblastoma cancer (HepG2) cells |
| Q49256920 | Antihepatocellular Carcinoma Potential of Tetramethylpyrazine Induces Cell Cycle Modulation and Mitochondrial-Dependent Apoptosis: Regulation of p53 Signaling Pathway in HepG2 Cells In Vitro. |
| Q61818588 | Antineoplastic Activity and Curative Role of Avenanthramides against the Growth of Ehrlich Solid Tumors in Mice |
| Q35161655 | Antitumor activity of SA12, a novel peptide, on SKBr-3 breast cancer cells via the mitochondrial apoptosis pathway |
| Q46458102 | Apaf-1-deficient fog mouse cell apoptosis involves hypo-polarization of the mitochondrial inner membrane, ATP depletion and citrate accumulation |
| Q24652950 | Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death |
| Q35605690 | Apoptosis and autoimmune disorders |
| Q53539196 | Apoptosis in spermatocytic and usual seminomas: a light microscopic and immunohistochemical study. |
| Q40526581 | Apoptosis of human melanoma cells by a combination of lonidamine and radiation |
| Q36074708 | Apoptosis-inducing factor (AIF) is targeted in IFN-α2a-induced Bid-mediated apoptosis through Bak activation in ovarian cancer cells |
| Q35595410 | Apoptotic pathways activated by histone deacetylase inhibitors: implications for the drug-resistant phenotype |
| Q36226739 | Apoptotic pathways and therapy resistance in human malignancies |
| Q41816998 | Assessing bioenergetic function in response to oxidative stress by metabolic profiling |
| Q24307389 | AtBAG6, a novel calmodulin-binding protein, induces programmed cell death in yeast and plants |
| Q33720034 | Athyrium multidentatum (Doll.) Ching extract induce apoptosis via mitochondrial dysfunction and oxidative stress in HepG2 cells |
| Q34053504 | BAG1: the guardian of anti-apoptotic proteins in acute myeloid leukemia |
| Q47254152 | BIM Binding Remotely Regulates BAX Activation: Insights from the Free Energy Landscapes |
| Q37718566 | Bacterial Carriers for Glioblastoma Therapy |
| Q81699206 | Bak but not Bax is essential for Bcl-xS-induced apoptosis |
| Q45119715 | Bax affects intracellular Ca2+ stores and induces Ca2+ wave propagation |
| Q79434810 | Bax and the mitochondrial permeability transition cooperate in the release of cytochrome c during endoplasmic reticulum-stress-induced apoptosis |
| Q37157948 | Bax, Bcl2, and p53 differentially regulate neomycin- and gentamicin-induced hair cell death in the zebrafish lateral line |
| Q80199717 | Bax-dependent mitochondrial membrane permeabilization enhances IRF3-mediated innate immune response during VSV infection |
| Q45190648 | Bax-induced cell death of Arabidopsis is meditated through reactive oxygen-dependent and -independent processes |
| Q36298500 | BaxΔ2 is a novel bax isoform unique to microsatellite unstable tumors |
| Q46060884 | Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. |
| Q37412841 | Bcl-2 family on guard at the ER. |
| Q34312445 | Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax |
| Q27338716 | Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death |
| Q28384299 | Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory |
| Q34583903 | Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation |
| Q39839664 | Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening. |
| Q46645046 | Caspase activation and apoptosis in response to proteasome inhibitors. |
| Q42129271 | Caspase-8 goes cardiolipin: a new platform to provide mitochondria with microdomains of apoptotic signals? |
| Q43227837 | Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells |
| Q36013981 | Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway |
| Q44557839 | Cell biology: metabolism meets death |
| Q35847611 | Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP |
| Q36655944 | Cell survival and apoptosis signaling as therapeutic target for cancer: marine bioactive compounds |
| Q80975685 | Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction |
| Q35605849 | Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101) |
| Q40007577 | Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway |
| Q58692747 | Combination Effect of Silver Nanoparticles and Histone Deacetylases Inhibitor in Human Alveolar Basal Epithelial Cells |
| Q35075375 | Combination of epinephrine with esmolol attenuates post-resuscitation myocardial dysfunction in a porcine model of cardiac arrest |
| Q37832083 | Combined modality therapy with TRAIL or agonistic death receptor antibodies. |
| Q40122436 | Control of Bax homodimerization by its carboxyl terminus. |
| Q36322786 | Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit |
| Q28245374 | Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor |
| Q53180574 | Crocin protects the liver and kidney from patulin-induced apoptosis in vivo. |
| Q90410100 | Curcumin Inhibited Podocyte Cell Apoptosis and Accelerated Cell Autophagy in Diabetic Nephropathy via Regulating Beclin1/UVRAG/Bcl2 |
| Q53543594 | Cyclosporin A inhibits programmed cell death and cytochrome c release induced by fusicoccin in sycamore cells. |
| Q34357003 | Cyr61 suppresses growth of human endometrial cancer cells |
| Q38944882 | DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines |
| Q50574015 | Deferoxamine Preconditioning of Neural-Like Cells Derived from Human Wharton's Jelly Mesenchymal Stem Cells as a Strategy to Promote Their Tolerance and Therapeutic Potential: An In Vitro Study. |
| Q52728305 | Deguelin exerts anticancer activity of human gastric cancer MGC-803 and MKN-45 cells in vitro. |
| Q53190888 | Diazoxide pretreatment enhances L6 skeletal myoblast survival and inhibits apoptosis induced by hydrogen peroxide. |
| Q35220743 | Differential regulation of apoptosis in slow and fast twitch muscles of aged female F344BN rats |
| Q42696421 | Dissimilar mechanisms of cytochrome c release induced by octyl glucoside-activated BAX and by BAX activated with truncated BID. |
| Q40154477 | Does transduced p27 induce apoptosis in human tumor cell lines? |
| Q37710926 | Double knockout of Bax and Bak from kidney proximal tubules reduces unilateral urethral obstruction associated apoptosis and renal interstitial fibrosis |
| Q40330255 | Down regulation of N-acetylglucosaminyltransferase V facilitates all-transretinoic acid to induce apoptosis of human hepatocarcinoma cells |
| Q34749989 | Downregulation of citrin, a mitochondrial AGC, is associated with apoptosis of hepatocytes |
| Q33927271 | Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy |
| Q39768159 | Dynamics of RASSF1A/MOAP-1 association with death receptors. |
| Q33270972 | E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation. |
| Q37359410 | ER-Golgi network--a future target for anti-cancer therapy |
| Q39301888 | Effect of Nigella sativa fixed oil on ethanol toxicity in rats |
| Q35120046 | Electroacupuncture stimulates remodeling of extracellular matrix by inhibiting apoptosis in a rabbit model of disc degeneration |
| Q30485574 | Elevated hydrostatic pressure triggers release of OPA1 and cytochrome C, and induces apoptotic cell death in differentiated RGC-5 cells |
| Q42372011 | Enteric glial cells counteract Clostridium difficile Toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways. |
| Q35756884 | Epidermal growth factor and trail interactions in epithelial-derived cells. |
| Q34216296 | Essential oil from Cryptomeria japonica induces apoptosis in human oral epidermoid carcinoma cells via mitochondrial stress and activation of caspases. |
| Q33490966 | Estrogen induces caspase-dependent cell death during hypothalamic development. |
| Q36694694 | Exenatide Reduces Tumor Necrosis Factor-α-induced Apoptosis in Cardiomyocytes by Alleviating Mitochondrial Dysfunction |
| Q37139298 | Expansion and evolution of cell death programmes |
| Q34596329 | Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis |
| Q24338213 | FAST is a BCL-X(L)-associated mitochondrial protein |
| Q35905850 | FFA-ROS-P53-mediated mitochondrial apoptosis contributes to reduction of osteoblastogenesis and bone mass in type 2 diabetes mellitus |
| Q39776170 | Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis. |
| Q33986486 | Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice |
| Q35628367 | Flirting in little space: the ER/mitochondria Ca2+ liaison |
| Q36139676 | Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway |
| Q41982710 | Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death |
| Q36259123 | Genetic dissection of the permeability transition pore |
| Q40530125 | Global investigation of p53-induced apoptosis through quantitative proteomic profiling using comparative amino acid-coded tagging |
| Q39879211 | Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization |
| Q35457276 | Heroin activates ATF3 and CytC via c-Jun N-terminal kinase pathways to mediate neuronal apoptosis |
| Q24634709 | Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism |
| Q79317948 | Histone H1.2 as a trigger for apoptosis |
| Q38217666 | Histone deacetylase inhibitors and cell death |
| Q37425266 | Host-cell interactions with pathogenic Rickettsia species |
| Q42179078 | Human papillomavirus types detected in skin warts and cancer differ in their transforming properties but commonly counteract UVB induced protective responses in human keratinocytes |
| Q35958188 | Human platelet lysate improves human cord blood derived ECFC survival and vasculogenesis in three dimensional (3D) collagen matrices |
| Q35528996 | Hydrogen peroxide signaling is required for glucocorticoid-induced apoptosis in lymphoma cells |
| Q40607355 | Hypoxia selection of death-resistant cells. A role for Bcl-X(L). |
| Q39251807 | Imperatorin sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells |
| Q35761034 | Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas |
| Q34690883 | Increased stability of Bcl-2 in HSP70-mediated protection against apoptosis induced by oxidative stress |
| Q32182272 | Induction of cell death by pyropheophorbide-α methyl ester-mediated photodynamic therapy in lung cancer A549 cells. |
| Q35131723 | Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis. |
| Q36124790 | Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways |
| Q45871499 | Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer |
| Q35068223 | Inhibitory effect of Curcuma purpurascens BI. rhizome on HT-29 colon cancer cells through mitochondrial-dependent apoptosis pathway |
| Q48116744 | Injury-induced neurogenesis in Bax-deficient mice: evidence for regulation by voltage-gated potassium channels |
| Q58201468 | Intersectin-1s Regulates the Mitochondrial Apoptotic Pathway in Endothelial Cells |
| Q36753390 | Intersection between mitochondrial permeability pores and mitochondrial fusion/fission. |
| Q30454411 | Intracellular mechanisms of aminoglycoside-induced cytotoxicity. |
| Q36263962 | Intracellular signaling mechanisms of acetaminophen-induced liver cell death |
| Q40337882 | Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis |
| Q34024008 | Iridoid glycosides fraction of Folium syringae leaves modulates NF-κB signal pathway and intestinal epithelial cells apoptosis in experimental colitis |
| Q34522154 | Is MAC the knife that cuts cytochrome c from mitochondria during apoptosis? |
| Q34630758 | Is mPTP the gatekeeper for necrosis, apoptosis, or both? |
| Q47121976 | JNK inhibitor alleviates apoptosis of fetal neural stem cells induced by emulsified isoflurane |
| Q37190224 | Knockdown of long non-coding RNA TP73-AS1 inhibits cell proliferation and induces apoptosis in esophageal squamous cell carcinoma |
| Q37251618 | LIGHT/IFN-γ triggers β cells apoptosis via NF-κB/Bcl2-dependent mitochondrial pathway |
| Q57724726 | Liver Toxicology |
| Q92960020 | Long non‑coding RNA GAS5 regulates myocardial ischemia‑reperfusion injury through the PI3K/AKT apoptosis pathway by sponging miR‑532‑5p |
| Q42426530 | Long-chain ceramide is a potent inhibitor of the mitochondrial permeability transition pore |
| Q45280303 | Long-term in vivo inhibition of CNS neurodegeneration by Bcl-XL gene transfer |
| Q37677213 | MAC and Bcl-2 family proteins conspire in a deadly plot |
| Q39898924 | MGMT hypermethylation and BCL-2 overexpression associated with superficial bladder cancer and recurrence. |
| Q53205630 | Mangiferin Protects Retinal Ganglion Cells in Ischemic Mouse Retina via SIRT1. |
| Q28582933 | Mechanical stretch induces mitochondria-dependent apoptosis in neonatal rat cardiomyocytes and G2/M accumulation in cardiac fibroblasts |
| Q36474134 | Mechanisms of acupuncture and moxibustion in regulation of epithelial cell apoptosis in rat ulcerative colitis |
| Q36080596 | Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein |
| Q38552126 | Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis |
| Q46179529 | Metformin Protects against Experimental Acrylamide Neuropathy in Rats. |
| Q40549699 | Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study |
| Q46971446 | Metformin promotes isolated rat liver mitochondria impairment. |
| Q39460442 | Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation |
| Q28574259 | Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria |
| Q36359505 | Mitochondria as a target for early detection and diagnosis of cancer |
| Q37704270 | Mitochondria as decision-makers in cell death |
| Q36226733 | Mitochondria as functional targets of proteins coded by human tumor viruses |
| Q27024426 | Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies |
| Q47421966 | Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. |
| Q55214653 | Mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency increases cisplatin-induced oxidative damage in the kidney tubule cells. |
| Q28388183 | Mitochondrial adaptations to oxidative stress confer resistance to apoptosis in lymphoma cells |
| Q42159376 | Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells |
| Q41998493 | Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. |
| Q40536857 | Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells |
| Q47738377 | Mitochondrial pathway is involved in hydrogen-peroxide-induced apoptotic cell death of oligodendrocytes |
| Q39961067 | Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death |
| Q40126186 | Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death. |
| Q24534853 | Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite |
| Q28190322 | Myc pathways provoking cell suicide and cancer |
| Q92940880 | Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway |
| Q40545931 | Myxoma virus M11L prevents apoptosis through constitutive interaction with Bak. |
| Q36346832 | Near death experiences: poxvirus regulation of apoptotic death |
| Q34096169 | Neuronal apoptosis in cerebral ischemia/reperfusion area following electrical stimulation of fastigial nucleus |
| Q46589169 | Neuroprotection of aucubin in primary diabetic encephalopathy |
| Q84912795 | Neuroprotective effect of crocin on acrylamide-induced cytotoxicity in PC12 cells |
| Q44893903 | Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53- and Bax-dependent pathways |
| Q86332223 | Non-canonical function of Bax in stress-induced nuclear protein redistribution |
| Q38188467 | Novel therapeutic strategies for traumatic brain injury: acute antioxidant reinforcement |
| Q46930696 | Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm |
| Q40426940 | Oocyte-based screening of cytokinesis inhibitors and identification of pectenotoxin-2 that induces Bim/Bax-mediated apoptosis in p53-deficient tumors |
| Q30485835 | Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization |
| Q60056610 | Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts |
| Q38790429 | Oridonin Inhibits Cell Proliferation and Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes |
| Q39000605 | Paeoniflorin protects cells from GalN/TNF-α-induced apoptosis via ER stress and mitochondria-dependent pathways in human L02 hepatocytes |
| Q35785899 | Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood? |
| Q62028003 | Pharmacological inhibitors of NF-κB accelerate apoptosis in chronic lymphocytic leukaemia cells |
| Q24318108 | Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32 |
| Q37375593 | Preclinical Studies of a Kidney Safe Iodinated Contrast Agent |
| Q34859364 | Programmed cell death and new discoveries in the genetics of parkinsonism. |
| Q82029479 | Programmed cell death in Parkinson's disease |
| Q44920105 | Progression of hair cell ejection and molecular markers of apoptosis in the avian cochlea following gentamicin treatment |
| Q37267118 | Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells |
| Q28510195 | Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation |
| Q40604705 | Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells |
| Q37222010 | Protective effects of onion-derived quercetin on glutamate-mediated hippocampal neuronal cell death |
| Q47555271 | Protective role of Nrf2 against mechanical-stretch-induced apoptosis in mouse fibroblasts: a potential therapeutic target of mechanical-trauma-induced stress urinary incontinence |
| Q24563065 | Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex |
| Q45010004 | Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination |
| Q50503023 | Recombination adenovirus-mediated human lactoferrin cDNA inhibits the growth of human MCF-7 breast cancer cells. |
| Q37027420 | Regulation and pathological role of bid in ischemic acute kidney injury |
| Q40526693 | Regulation of caspase-3 and -9 activation in oxidant stress to RTE by forkhead transcription factors, Bcl-2 proteins, and MAP kinases |
| Q37081740 | Regulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and Bid |
| Q39789593 | Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L). |
| Q21564051 | Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins |
| Q28245783 | Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation |
| Q90216154 | Regulatory mechanism of NOV/CCN3 in the inflammation and apoptosis of lung epithelial alveolar cells upon lipopolysaccharide stimulation |
| Q36873707 | Rescuing neurons and glia: is inhibition of apoptosis useful? |
| Q36216542 | Role and mechanism of hypoxia-inducible factor-1 in cell growth and apoptosis of breast cancer cell line MDA-MB-231 |
| Q37679979 | Role of Notch signaling pathway in pancreatic cancer |
| Q41922999 | Role of autophagy in oncolytic herpes simplex virus type 1-induced cell death in squamous cell carcinoma cells |
| Q90442747 | Roles of ERK1/2 and PI3K/AKT signaling pathways in mitochondria-mediated apoptosis in testes of hypothyroid rats |
| Q38878861 | Salvianolic acid A attenuates TNF-α- and D-GalN-induced ER stress-mediated and mitochondrial-dependent apoptosis by modulating Bax/Bcl-2 ratio and calcium release in hepatocyte LO2 cells |
| Q42264580 | Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. |
| Q46842557 | Significance of survivin and Bcl-2 homologous antagonist/killer mRNA in detection of bone metastasis in patients with breast cancer. |
| Q34158665 | Sirt3 protects cortical neurons against oxidative stress via regulating mitochondrial Ca2+ and mitochondrial biogenesis |
| Q46189582 | Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo |
| Q37571963 | Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert |
| Q50350473 | Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530. |
| Q41979916 | Static mechanical stress induces apoptosis in rat endplate chondrocytes through MAPK and mitochondria-dependent caspase activation signaling pathways |
| Q40179590 | Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons |
| Q64927200 | Streptolysin O derived from Streptococcus pyogenes inhibits RANKL‑induced osteoclastogenesis through the NF‑κB signaling pathway. |
| Q35594655 | Strophalloside induces apoptosis of SGC-7901 cells through the mitochondrion-dependent caspase-3 pathway. |
| Q43298298 | Synergistic activity of sorafenib and betulinic acid against clonogenic activity of non-small cell lung cancer cells. |
| Q38743483 | Synthesis and anticancer and lipophilic properties of 10-dialkylaminobutynyl derivatives of 1,8- and 2,7-diazaphenothiazines |
| Q61795681 | Synthesis, Anticancer Activity, and Apoptosis Induction of Novel 3,6-Diazaphenothiazines |
| Q28301197 | TIP30 regulates apoptosis-related genes in its apoptotic signal transduction pathway |
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| Q37232979 | TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: involvement of Notch-1 signaling pathway |
| Q83158104 | Targeting mitochondria for cancer therapy |
| Q28285037 | Taxol induces caspase-10-dependent apoptosis |
| Q37233196 | The Bmi-1 polycomb group gene in skin cancer: regulation of function by (-)-epigallocatechin-3-gallate |
| Q35029111 | The Differential Effect of Toxoplasma Gondii Infection on the Stability of BCL2-Family Members Involves Multiple Activities |
| Q40586654 | The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members. |
| Q41566564 | The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma |
| Q34567914 | The Protective Effect of Beraprost Sodium on Diabetic Cardiomyopathy through the Inhibition of the p38 MAPK Signaling Pathway in High-Fat-Induced SD Rats |
| Q46842154 | The cardioprotective effects of L-carnitine on rat cardiac injury, apoptosis, and oxidative stress caused by amethopterin |
| Q89767729 | The cell biology of mitochondrial membrane dynamics |
| Q24296818 | The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activity |
| Q24673883 | The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis |
| Q33882877 | The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism |
| Q54637092 | The neuroprotective effect of carnosine (β-alanyl-L-histidine) on retinal ganglion cell following ischemia-reperfusion injury. |
| Q58454328 | The permeability transition and BCL-2 family proteins in apoptosis: co-conspirators or independent agents? |
| Q40181421 | The role of anti-alpha-enolase autoantibodies in pathogenicity of autoimmune-mediated retinopathy. |
| Q89151907 | The role of apoptosis in acetaminophen hepatotoxicity |
| Q36733723 | The role of the mitochondria in mediating cytotoxicity of anti-cancer therapies |
| Q34451529 | The role of the mitochondrial apoptosis induced channel MAC in cytochrome c release |
| Q38143040 | The roles of traditional chinese medicine: shen-fu injection on the postresuscitation care bundle |
| Q24305092 | The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death |
| Q39611834 | The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation |
| Q24310440 | The vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein Bax |
| Q47073279 | The zebrafish bcl-2 homologue Nrz controls development during somitogenesis and gastrulation via apoptosis-dependent and -independent mechanisms. |
| Q42638167 | Tissue transglutaminase is a multifunctional BH3-only protein |
| Q39672418 | Toxoplasma gondii infection inhibits the mitochondrial apoptosis through induction of Bcl-2 and HSP70 |
| Q37407088 | Triptolide exerts pro-apoptotic and cell cycle arrest activity on drug-resistant human lung cancer A549/Taxol cells via modulation of MAPK and PI3K/Akt signaling pathways |
| Q35082212 | Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation |
| Q38164707 | Viruses as modulators of mitochondrial functions |
| Q36242512 | Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons |
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| Q46691950 | Zearalenone-induced changes in biochemical parameters, oxidative stress and apoptosis in cardiac tissue: Protective role of crocin |
| Q39221377 | mTORC1 inhibitor rapamycin and ER stressor tunicamycin induce differential patterns of ER-mitochondria coupling |
| Q52655160 | miR-145 suppresses the proliferation, invasion and migration of NSCLC cells by regulating the BAX/BCL-2 ratio and the caspase-3 cascade. |
| Q52655155 | miR-30d inhibits cell biological progression of Ewing's sarcoma by suppressing the MEK/ERK and PI3K/Akt pathways in vitro. |
| Q39045002 | p21 overexpression sensitizes osteosarcoma U2OS cells to cisplatin via evoking caspase-3 and Bax/Bcl-2 cascade |
| Q46492409 | p53 and Bcl-2expression in response to boldenone induced liver cells injury. |
| Q46793193 | γ-Rays-generated ROS induce apoptosis via mitochondrial and cell cycle alteration in smooth muscle cells. |
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