Neuroprotection by the inhibition of apoptosis

scientific article

Neuroprotection by the inhibition of apoptosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1750-3639.2000.TB00262.X
P698PubMed publication ID10764048

P2093author name stringCrocker SJ
Nicholson DW
Robertson GS
Schulz JB
P2860cites workA novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicingQ22008514
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The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophyQ24308680
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genesQ24315805
X-linked IAP is a direct inhibitor of cell-death proteasesQ24318710
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspasesQ24532851
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspasesQ24533214
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosisQ27732868
A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE)Q27739379
The CARD domain: a new apoptotic signalling motifQ28239887
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICADQ28258328
A single BIR domain of XIAP sufficient for inhibiting caspasesQ28266409
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosisQ28292299
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymeraseQ28302692
Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampusQ28568186
Identification and characterization of a spinal muscular atrophy-determining geneQ29547495
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosisQ29617776
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9Q29618617
Caspase structure, proteolytic substrates, and function during apoptotic cell deathQ33782479
Decreased apoptosis in the brain and premature lethality in CPP32-deficient miceQ34408475
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosisQ34451533
Prevention of apoptosis by a baculovirus gene during infection of insect cellsQ34993245
Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damageQ36030783
Control of programmed cell death by the baculovirus genes p35 and iap.Q36662781
Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.Q36684306
Constitutive expression of zif268 in neocortex is regulated by synaptic activityQ37530737
Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's diseaseQ39116027
Programmed cell death and the control of cell survival: lessons from the nervous systemQ40777905
Non-specific effects of methyl ketone peptide inhibitors of caspasesQ40977161
ITA, a vertebrate homologue of IAP that is expressed in T lymphocytesQ41153607
Fetal nigral transplantation as a therapy for Parkinson's diseaseQ41367101
Neurotrophic 3,9-bis[(alkylthio)methyl]-and-bis(alkoxymethyl)-K-252a derivativesQ42439874
Ischemia-induced CA1 neuronal death is preceded by elevated FosB and Jun expression and reduced NGFI-A and JunB levels.Q42455690
Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.Q42536897
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspasesQ42657216
Ischemic damage in the striatum of adult gerbils: relative sparing of somatostatinergic and cholinergic interneurons contrasts with loss of efferent neuronsQ45825152
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell deathQ46725238
Potassium deprivation-induced apoptosis of cerebellar granule neurons: cytochrome c release in the absence of altered expression of Bcl-2 family proteins.Q47727128
Staurosporine and K-252 compounds protect hippocampal neurons against amyloid beta-peptide toxicity and oxidative injuryQ48090525
Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.Q48236502
Caspase inhibition reduces apoptosis and increases survival of nigral transplantsQ48308615
Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activationQ48373661
Endonucleolytic DNA fragmentation is not required for apoptosis of cultured rat cerebellar granule neurons.Q48465287
Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.Q48513221
Bacterial alkaloids mitigate seizure-induced hippocampal damage and spatial memory deficits.Q48912664
Selective resistance of sensory cells of the mesencephalic trigeminal nucleus to kainic acid-induced lesions.Q54568034
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)283-292
P577publication date2000-04-01
P1433published inBrain PathologyQ4955776
P1476titleNeuroprotection by the inhibition of apoptosis
P478volume10

Reverse relations

cites work (P2860)
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