scholarly article | Q13442814 |
P2093 | author name string | C E Turner | |
J T Miller | |||
S L Bellis | |||
P433 | issue | 29 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 17437-41 | |
P577 | publication date | 1995-07-21 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase | |
P478 | volume | 270 |
Q38716292 | A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells. |
Q35019176 | A deficiency of uPAR alters endothelial angiogenic function and cell morphology |
Q35441413 | A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction |
Q34923837 | A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation |
Q41140861 | AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination |
Q41870410 | ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts |
Q57039912 | Activation of Human Endothelial Cells via S-Endo-1 Antigen (CD146) Stimulates the Tyrosine Phosphorylation of Focal Adhesion Kinase p125FAK |
Q36255267 | Activation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domains |
Q36063824 | Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor |
Q42987160 | Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin |
Q35914413 | Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin |
Q28140811 | Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1 |
Q27314883 | Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes |
Q46485748 | Amelioration of neutrophil membrane function underlies granulocyte-colony stimulating factor action in glycogen storage disease 1b. |
Q53324593 | Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. |
Q41099656 | Assembly of focal adhesions: progress, paradigms, and portents |
Q42487726 | Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells. |
Q42134573 | Autophosphorylation of Tyr397 and its phosphorylation by Src-family kinases are altered in focal-adhesion-kinase neuronal isoforms |
Q35274621 | BAG3 regulates formation of the SNARE complex and insulin secretion |
Q24318315 | Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin |
Q30436893 | CaMK-II promotes focal adhesion turnover and cell motility by inducing tyrosine dephosphorylation of FAK and paxillin. |
Q39120121 | Caffeic acid regulates LPS-induced NF-κB activation through NIK/IKK and c-Src/ERK signaling pathways in endothelial cells |
Q24318621 | Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions |
Q22008792 | Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins |
Q91387651 | Cellular rescue in a zebrafish model of congenital muscular dystrophy type 1A |
Q37438399 | Clostridium difficile toxin A binds colonocyte Src causing dephosphorylation of focal adhesion kinase and paxillin |
Q30454300 | Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases |
Q87891576 | Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle |
Q36956209 | Cross talk between paxillin and Rac is critical for mediation of barrier-protective effects by oxidized phospholipids |
Q24554072 | Cross talk of pp125(FAK) and pp59(Lyn) non-receptor tyrosine kinases to insulin-mimetic signaling in adipocytes |
Q37365788 | Cytokine signaling through the novel tyrosine kinase RAFTK in Kaposi's sarcoma cells |
Q35546483 | Cytoskeletal remodeling of the airway smooth muscle cell: a mechanism for adaptation to mechanical forces in the lung. |
Q77764241 | Decreased tyrosine phosphorylation of focal adhesion kinase after estradiol treatment of MCF-7 human breast carcinoma cells |
Q43540351 | Depletion of focal adhesion kinase by antisense depresses contractile activation of smooth muscle |
Q91692469 | Dibutyltin(IV) and Tributyltin(IV) Derivatives of meso-Tetra(4-sulfonatophenyl)porphine Inhibit the Growth and the Migration of Human Melanoma Cells |
Q77861094 | Dibutyryl cyclic AMP-induced process formation in astrocytes is associated with a decrease in tyrosine phosphorylation of focal adhesion kinase and paxillin |
Q43649354 | Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies |
Q30441980 | Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells |
Q40755285 | Differential regulation of components of the focal adhesion complex by heregulin: role of phosphatase SHP-2. |
Q34542007 | Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis |
Q35478122 | EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment |
Q33289370 | Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells |
Q47322385 | Elastase Alters Contractility and Promotes an Inflammatory Synthetic Phenotype in Airway Smooth Muscle Tissues |
Q40342689 | Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. |
Q54976490 | Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development. |
Q64294956 | Endothelial Differentiation G Protein-Coupled Receptor 5 Plays an Important Role in Induction and Maintenance of Pluripotency |
Q41828281 | Enhanced interaction between focal adhesion and adherens junction proteins: involvement in sphingosine 1-phosphate-induced endothelial barrier enhancement |
Q43938111 | Epidermal growth factor stimulates serine/threonine phosphorylation of the focal adhesion protein paxillin in a MEK-dependent manner in normal rat kidney cells |
Q30429931 | Estrogen Stimulation of Cell Migration Involves Multiple Signaling Pathway Interactions |
Q36308168 | Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance |
Q30164536 | Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development |
Q37237616 | FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion |
Q39898155 | FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas |
Q92661891 | FAK-Dependent Cell Motility and Cell Elongation |
Q29616029 | FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly |
Q89617856 | Feeling Things Out: Bidirectional Signaling of the Cell-ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation |
Q36700252 | Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization |
Q42784215 | Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype |
Q24555199 | Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy |
Q41133079 | Focal adhesion kinase inhibitors are potent anti-angiogenic agents. |
Q40725761 | Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA. |
Q28301647 | Focal adhesion kinase is essential for costamerogenesis in cultured skeletal muscle cells |
Q54530703 | Focal adhesion kinase localizes to sites of cell-to-cell contact in vivo and increases apically in rat uterine luminal epithelium and the blastocyst at the time of implantation. |
Q34718705 | Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin |
Q40958357 | Glucocorticoid effect on human mesangial cell cytoskeletal proteins |
Q46775424 | Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability |
Q88714305 | Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices |
Q92502745 | Hic-5 regulates Src-induced invadopodia rosette formation and organization |
Q24550885 | Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase |
Q42990819 | Hormonal regulation of focal adhesions in bovine adrenocortical cells: induction of paxillin dephosphorylation by adrenocorticotropic hormone |
Q36840425 | How do protein kinases recognize their substrates? |
Q24523677 | Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells. |
Q34683501 | IL-1beta during in vitro decidualization in primate |
Q24646348 | Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T |
Q24681861 | Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding |
Q35197497 | Identification of novel focal adhesion kinase substrates: role for FAK in NFκB signaling |
Q38826975 | In Vitro and In Vivo Anti-Melanoma Effects of Pituranthos tortuosus Essential Oil Via Inhibition of FAK and Src Activities |
Q30442141 | Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase |
Q34626911 | Influence of airway wall compliance on epithelial cell injury and adhesion during interfacial flows |
Q37381921 | Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation |
Q42266260 | Insulin and insulin-like growth factor-1 stimulate dephosphorylation of paxillin in parallel with focal adhesion kinase |
Q28289288 | Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src) |
Q40601260 | Insulin-like growth factor-I signaling in human neuroblastoma cells. |
Q28139276 | Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST |
Q52201536 | Integrin alpha v beta 5-dependent serine phosphorylation of paxillin in cultured human macrophages adherent to vitronectin. |
Q22003881 | Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase |
Q34310352 | Invited review: focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle |
Q40001007 | Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression. |
Q40272691 | Involvement of the paxillin pathway in JB6 Cl41 cell transformation |
Q30009312 | Kindlin-2 tyrosine phosphorylation and interaction with Src serve as a regulatable switch in the integrin outside-in signaling circuit |
Q39478320 | LPS induces phosphorylation of actin-regulatory proteins leading to actin reassembly and macrophage motility |
Q28508545 | Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes |
Q37688163 | MIEN1 drives breast tumor cell migration by regulating cytoskeletal-focal adhesion dynamics |
Q34002994 | Mesenchymal migration as a therapeutic target in glioblastoma |
Q28363290 | Multiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillin |
Q39355375 | Multiplexed high content screening reveals that cigarette smoke condensate-altered cell signaling pathways are accentuated through FAK inhibition in human bronchial cells |
Q28586815 | Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation |
Q36854943 | Myosin IIC: a third molecular motor driving neuronal dynamics |
Q47764794 | Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. |
Q27341844 | Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels |
Q40650766 | Nuclear translocation of Xenopus laevis paxillin |
Q40980028 | PGE2 Promotes the Migration of Mesenchymal Stem Cells through the Activation of FAK and ERK1/2 Pathway. |
Q28286397 | Paxillin |
Q24682031 | Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling |
Q92483910 | Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX |
Q35194986 | Paxillin alpha and Crk-associated substrate exert opposing effects on cell migration and contact inhibition of growth through tyrosine phosphorylation |
Q54364576 | Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature. |
Q28142041 | Paxillin and focal adhesion signalling |
Q41145689 | Paxillin association in vitro with integrin cytoplasmic domain peptides |
Q30437439 | Paxillin is involved in the differential regulation of endothelial barrier by HGF and VEGF. |
Q36098165 | Paxillin phosphorylation and complexing with Erk and FAK are regulated by PLD activity in MDA-MB-231 cells |
Q35832209 | Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. |
Q37650990 | Paxillin: a crossroad in pathological cell migration |
Q30167845 | Paxillin: a focal adhesion-associated adaptor protein |
Q41032613 | Pervanadate stimulates amylase release and protein tyrosine phosphorylation of paxillin and p125(FAK) in differentiated AR4-2J pancreatic acinar cells |
Q89728821 | Phospholipid phosphatase related 1 (PLPPR1) increases cell adhesion through modulation of Rac1 activity |
Q54047415 | Phosphorylation of Hic-5 at tyrosine 60 by CAKbeta and Fyn. |
Q34528472 | Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling |
Q27319440 | Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover |
Q30175229 | Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells |
Q36677467 | Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle |
Q30442189 | Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation |
Q44116699 | Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants |
Q44510433 | Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants |
Q77344280 | Purification and assays for paxillin |
Q30442069 | Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal |
Q42812456 | Reduced focal adhesion kinase and paxillin phosphorylation in BCR-ABL-transfected cells |
Q30486408 | Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells |
Q22254735 | Regulation of neutrophil adhesion by pituitary growth hormone accompanies tyrosine phosphorylation of Jak2, p125FAK, and paxillin |
Q41472107 | Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis |
Q54469665 | Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells. |
Q35127964 | Role of tyrosine kinase signaling in endothelial cell barrier regulation |
Q43957570 | Roles for the tubulin- and PTP-PEST-binding paxillin LIM domains in cell adhesion and motility |
Q43710099 | Selected contribution: roles of focal adhesion kinase and paxillin in the mechanosensitive regulation of myosin phosphorylation in smooth muscle |
Q36888890 | Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin |
Q73283298 | Serine phosphorylation of paxillin by heregulin-beta1: role of p38 mitogen activated protein kinase |
Q28198051 | Signaling through focal adhesion kinase |
Q34657924 | Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure. |
Q43669542 | Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury |
Q78127469 | Syk and paxillin are differentially phosphorylated following adhesion to the plastic substrate in rat alveolar macrophages |
Q30739769 | TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase |
Q35139916 | Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis |
Q36253834 | Targeted Inhibition of Src Kinase Signaling Attenuates Pancreatic Tumorigenesis |
Q30530606 | Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells |
Q36973195 | Targeting Drug-Sensitive and -Resistant Strains of Mycobacterium tuberculosis by Inhibition of Src Family Kinases Lowers Disease Burden and Pathology |
Q58726403 | Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions |
Q44630339 | Tension development during contractile stimulation of smooth muscle requires recruitment of paxillin and vinculin to the membrane |
Q36744048 | The Lhx9-integrin pathway is essential for positioning of the proepicardial organ |
Q45067787 | The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK. |
Q36646335 | The beta1 integrin activates JNK independent of CagA, and JNK activation is required for Helicobacter pylori CagA+-induced motility of gastric cancer cells |
Q44067085 | The focal adhesion protein paxillin regulates contraction in canine tracheal smooth muscle |
Q35920891 | The interplay between Src and integrins in normal and tumor biology |
Q36313281 | The potential for the use of nanofeaturing in medical devices |
Q34117467 | The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase |
Q41145819 | The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells. |
Q40912830 | The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin |
Q36298301 | The small GTPase RhoA regulates the contraction of smooth muscle tissues by catalyzing the assembly of cytoskeletal signaling complexes at membrane adhesion sites |
Q26777016 | Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy |
Q34125340 | Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migration |
Q40866648 | Turnover of focal adhesions and cancer cell migration |
Q34341785 | Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4. |
Q41942809 | Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton |
Q38772631 | UM-164: a potent c-Src/p38 kinase inhibitor with in vivo activity against triple negative breast cancer |
Q47448333 | VANGL2 interacts with integrin αv to regulate matrix metalloproteinase activity and cell adhesion to the extracellular matrix |
Q28240564 | Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells |
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Q33884170 | c-Src-mediated phosphorylation of TRIP6 regulates its function in lysophosphatidic acid-induced cell migration |
Q42652785 | mRNA sequence of the Xenopus laevis paxillin gene and its expression |
Q37700181 | β-arrestin 2-dependent activation of ERK1/2 is required for ADP-induced paxillin phosphorylation at Ser(83) and microglia chemotaxis |
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