Activation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domains

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Activation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domains is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.141.1.241
P932PMC publication ID2132721
P698PubMed publication ID9531562
P5875ResearchGate publication ID51323993

P2093author name stringP J McKeown-Longo
J Sottile
D C Hocking
P2860cites workpp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesionsQ24561464
Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinaseQ24619015
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assemblyQ24642753
Effects of cytochalasin and phalloidin on actinQ24680210
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
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Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding regionQ28287066
Integrins: a family of cell surface receptorsQ28288125
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinaseQ28293659
Identification of the fibronectin sequences required for assembly of a fibrillar matrixQ28645670
Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the moleculeQ29616413
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient miceQ29617498
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectinQ29617865
Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAKQ30450284
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for CrkQ30452729
Focal adhesion kinase and associated proteinsQ30465310
A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.Q30468168
Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptorQ34686171
Partial primary structure of bovine plasma fibronectin: Three types of internal homologyQ34707857
Assembly of extracellular matrixQ35455410
Interaction of the 70,000-mol-wt amino-terminal fragment of fibronectin with the matrix-assembly receptor of fibroblastsQ36211533
Induction of fibronectin matrix assembly in human fibrosarcoma cells by dexamethasoneQ36216349
Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organizationQ36221243
Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (alpha 5 beta 1) antibodies.Q36223428
Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strengthQ36232820
A novel role for the integrin-binding III-10 module in fibronectin matrix assemblyQ36236743
Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinityQ36237442
Paxillin is a major phosphotyrosine-containing protein during embryonic developmentQ36532880
A fibronectin self-assembly site involved in fibronectin matrix assembly: reconstruction in a synthetic peptideQ36533193
Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferationQ37381921
Variants of the cell recognition site of fibronectin that retain attachment-promoting activityQ37569976
Fibronectin's III-1 module contains a conformation-dependent binding site for the amino-terminal region of fibronectin.Q38306135
Regulation of the avidity of integrin alpha 4 beta 7 by the beta 7 cytoplasmic domain.Q38308078
Five type I modules of fibronectin form a functional unit that binds to fibroblasts and Staphylococcus aureusQ38334353
Physiology of FibronectinQ40142052
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa proteinQ40642924
Integrin activation: the link between ligand binding and signal transductionQ40924680
Adhesion in cell migrationQ40952555
The molecular architecture of focal adhesionsQ41020989
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifsQ41334070
Fibronectin's amino-terminal matrix assembly site is located within the 29-kDa amino-terminal domain containing five type I repeatsQ41358779
Microfilament reorganization is associated with functional activation of alpha M beta 2 on monocytic cellsQ41488402
Superfibronectin is a functionally distinct form of fibronectinQ41494889
Substrate-specific binding of the amino terminus of fibronectin to an integrin complex in focal adhesionsQ41498852
Signaling between the Extracellular Matrix and the Cytoskeleton: Tyrosine Phosphorylation and Focal Adhesion AssemblyQ41651876
Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β SubunitQ41690746
Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cellsQ41740694
Arginine-glycine-aspartic acid adhesion receptorsQ41786100
N-terminal type I modules required for fibronectin binding to fibroblasts and to fibronectin's III1 moduleQ42062491
Controlled induction of focal adhesion disassembly and migration in primary fibroblasts.Q42809072
Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrixQ42824269
Filament arrangements in negatively stained cultured cells: the organization of actinQ42830885
The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity.Q45938073
Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domainQ46599137
Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cellsQ46722158
Localization of fibronectin matrix assembly sites on fibroblasts and endothelial cells.Q52524694
The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand OccupancyQ58058153
Isolation of a collagen-binding fragment from fibronectin and cold-insoluble globulinQ67469129
Role of the I-9 and III-1 modules of fibronectin in formation of an extracellular fibronectin matrixQ67690713
Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinaseQ67926191
Recombinant 70-kDa protein from the amino-terminal region of rat fibronectin inhibits binding of fibronectin to cells and bacteriaQ68406914
Location of a collagen-binding domain in fibronectinQ70524075
Cross-linking of the NH2-terminal region of fibronectin to molecules of large apparent molecular mass. Characterization of fibronectin assembly sites induced by the treatment of fibroblasts with lysophosphatidic acidQ71903344
Fibronectin and atherosclerosisQ71995100
Location of the cell-attachment site in fibronectin with monoclonal antibodies and proteolytic fragments of the moleculeQ72658991
Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensinQ72816625
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell adhesionQ187640
P1104number of pages13
P304page(s)241-253
P577publication date1998-04-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleActivation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domains
P478volume141

Reverse relations

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