Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin

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Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.148.4.825
P932PMC publication ID2169362
P698PubMed publication ID10684262

P2093author name stringA M Belkin
D Krylov
S S Akimov
L F Fleischman
P2860cites workThree-dimensional structure of a transglutaminase: human blood coagulation factor XIIIQ24564521
Characterization of cDNA coding for human factor XIIIaQ24629195
Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cellsQ28273706
Gh: a GTP-binding protein with transglutaminase activity and receptor signaling functionQ28578829
Affinity of human erythrocyte transglutaminase for a 42-kDa gelatin-binding fragment of human plasma fibronectinQ36223387
Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytesQ36233145
Transglutaminase-catalyzed matrix cross-linking in differentiating cartilage: identification of osteonectin as a major glutaminyl substrateQ36235525
Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing.Q36255000
Activation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domainsQ36255267
beta1-integrin cytoplasmic subdomains involved in dominant negative functionQ36863689
Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous systemQ37045225
Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).Q37379538
Biosynthesis and acquisition of biological activity of the fibronectin receptorQ38348191
Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosisQ40023599
TransglutaminasesQ40082696
Identification of a transforming growth factor-beta1/bone morphogenetic protein 4 (TGF-beta1/BMP4) response element within the mouse tissue transglutaminase gene promoterQ41040397
Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell deathQ41057277
Reduced expression of tissue transglutaminase in a human endothelial cell line leads to changes in cell spreading, cell adhesion and reduced polymerisation of fibronectin.Q41074541
Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoterQ41226836
Transfection of tissue transglutaminase into a highly malignant hamster fibrosarcoma leads to a reduced incidence of primary tumour growth.Q41438808
Localization of cellular transglutaminase on the extracellular matrix after wounding: characteristics of the matrix bound enzymeQ41653086
Regulation of transglutaminase type II by transforming growth factor-beta 1 in normal and transformed human epidermal keratinocytes.Q41728326
Transglutaminase-mediated processing of fibronectin by endothelial cell monolayersQ42491069
The binding sites on fibrin(ogen) for guinea pig liver transglutaminase are similar to those of blood coagulation factor XIII. Characterization of the binding of liver transglutaminase to fibrinQ42650835
Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesionQ42816111
Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.Q45296134
Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases.Q46233797
A filter paper assay for transamidating enzymes using radioactive amine substratesQ48024172
Transglutaminase facilitates the formation of polymers of the beta-amyloid peptideQ48088448
Transglutaminase activity is increased in Alzheimer's disease brainQ48762074
Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilizationQ53857269
Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells.Q53959200
Transglutaminase stabilizes melanoma adhesion under laminar flowQ54299547
Transglutaminase-catalyzed crosslinking of fibrils of collagen V/XI in A204 rhabdomyosarcoma cellsQ58212968
Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cellsQ67666231
Arrangement of cellular fibronectin in noncollagenous fibrils in human fibroblast culturesQ67882033
Tumor promoter and fibronectin induce actin stress fibers and focal adhesion sites in spreading human erythroleukemia (HEL) cellsQ68211548
Complexation of fibronectin with tissue transglutaminaseQ69369367
Differential expression of tissue transglutaminase in human cells. An immunohistochemical studyQ69371038
Reversible unfolding of the gelatin-binding domain of fibronectin: structural stability in relation to functionQ69596833
Identification of a substrate site for liver transglutaminase on the aminopropeptide of type III collagenQ69892884
Expression of tissue-type transglutaminase correlates positively with metastatic properties of human melanoma cell linesQ72427940
The fibronectin-binding domain of transglutaminaseQ72631476
Transglutaminase-catalyzed cross-linking of osteopontin is inhibited by osteocalcinQ73648523
Fibronectin type III repeats mediate RGD-independent adhesion and signaling through activated beta1 integrinsQ73935017
Distinct nuclear localization and activity of tissue transglutaminaseQ74516745
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectfibronectin-tissue transglutaminase complexQ22327313
alphaV-beta3 integrin-tissue transglutaminase complexQ22327317
alpha5-beta1 integrin-tissue transglutaminase complexQ22327319
alpha3-beta1 integrin-tissue transglutaminase complexQ22327335
alpha5-beta1 integrin-fibronectin-tissue transglutaminase complexQ22327336
alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complexQ22327337
alpha1-beta1 integrin-tissue transglutaminase complexQ22327338
P304page(s)825-38
P577publication date2000-02-21
P1433published inJournal of Cell BiologyQ1524550
P1476titleTissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin
P478volume148

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Q52365303Tissue transglutaminase regulates interactions between ovarian cancer stem cells and the tumor niche.
Q42626618Tissue transglutaminase, coagulation factor XIII, and the pro-polypeptide of von Willebrand factor are all ligands for the integrins alpha 9beta 1 and alpha 4beta 1.
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Q37434321Transglutaminase 2 as a novel activator of LRP6/β-catenin signaling
Q36633284Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis
Q39168249Transglutaminase 2 expression in acute myeloid leukemia: association with adhesion molecule expression and leukemic blast motility
Q38648421Transglutaminase 2 in cancer
Q48372615Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy.
Q35989247Transglutaminase 2 inhibitors and their therapeutic role in disease states
Q34161250Transglutaminase 2 inhibits apoptosis induced by calcium- overload through down-regulation of Bax
Q58064967Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies
Q37702089Transglutaminase 2 is essential for adherence of Porphyromonas gingivalis to host cells
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Q37057882Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells
Q35693361Transglutaminase 2: a molecular Swiss army knife
Q38736793Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor Formation.
Q38269678Transglutaminase as a therapeutic target for celiac disease
Q46561808Transglutaminase crosslinking of SIBLING proteins in teeth
Q42506814Transglutaminase inhibitors induce hyperproliferation and parakeratosis in tissue-engineered skin.
Q33707936Transglutaminase regulation of cell function.
Q41898516Transglutaminase type II plays a protective role in hepatic injury
Q37224569Transglutaminase-2 Is Involved in All-Trans Retinoic Acid-Induced Invasion and Matrix Metalloproteinases Expression of SH-SY5Y Neuroblastoma Cells via NF-κB Pathway
Q92219315Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression
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Q42243895Transglutaminase-mediated oligomerization of the fibrin(ogen) alphaC domains promotes integrin-dependent cell adhesion and signaling.
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