beta1-integrin cytoplasmic subdomains involved in dominant negative function

scientific article published on April 1998

beta1-integrin cytoplasmic subdomains involved in dominant negative function is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1091/MBC.9.4.715
P932PMC publication ID25300
P698PubMed publication ID9529373
P5875ResearchGate publication ID51321826

P2093author name stringR Fässler
A M Belkin
G Tarone
L Silengo
S F Retta
M J Humphries
G De Leo
F Balzac
P Ferraris
P2860cites workReplacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucoseQ24299251
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Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domainsQ24672461
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A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processingQ28264354
Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cellsQ28273706
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Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimerasQ28286227
Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motilityQ28286870
Interaction of focal adhesion kinase with cytoskeletal protein talinQ28294149
Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domainQ28298484
Focal adhesions, contractility, and signalingQ28299775
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activityQ28300726
Identification and characterization of a novel antigen complex on mouse mammary tumor cells using a monoclonal antibody against platelet glycoprotein IcQ28339255
Integrins and signal transduction pathways: the road takenQ29547895
Integrin function: molecular hierarchies of cytoskeletal and signaling moleculesQ29618843
Focal adhesion kinase and associated proteinsQ30465310
Ligand-dependent and -independent integrin focal contact localization: the role of the alpha chain cytoplasmic domainQ34437525
Inside-out integrin signallingQ35455358
Interaction of the 70,000-mol-wt amino-terminal fragment of fibronectin with the matrix-assembly receptor of fibroblastsQ36211533
Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organizationQ36221243
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expressionQ36221364
The mouse vitronectin receptor is a T cell activation antigenQ36229923
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions.Q36232656
Expression and functional analysis of a cytoplasmic domain variant of the beta 1 integrin subunitQ36233188
Integrin cytoplasmic domains mediate inside-out signal transductionQ36233869
Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cellsQ36532803
A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1Q36569275
Genomic organization of the mouse beta 1 gene: conservation of the beta 1D but not of the beta 1B and beta 1C integrin splice variants.Q36827067
Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain.Q38296610
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa proteinQ40642924
Anchorage dependence, integrins, and apoptosisQ40754534
Integrin cytoplasmic interactions and bidirectional transmembrane signallingQ40924688
Integrin transmembrane signaling and cytoskeletal controlQ40952551
Beta 1 integrin-dependent and -independent polymerization of fibronectinQ41254786
Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domainQ41455132
A cell surface integral membrane glycoprotein of 85,000 mol wt (gp85) associated with triton X-100-insoluble cell skeletonQ41459334
Panning transfected cells for electrophysiological studiesQ41519573
Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β SubunitQ41690746
Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cellsQ41740694
Construction and properties of an Epstein-Barr-virus-derived cDNA expression vector for human cellsQ41758390
Alpha 6.beta 1 integrin (laminin receptor) is down-regulated by tumor necrosis factor alpha and interleukin-1 beta in human endothelial cellsQ42455229
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocystsQ42771254
Breaking the integrin hinge. A defined structural constraint regulates integrin signalingQ43482152
Regulation of the fibronectin receptor affinity by divalent cations.Q44461951
Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.Q52210113
p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors.Q52508335
Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunitQ58058190
Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell linesQ58065088
Binding of soluble form of fibroblast surface protein, fibronectin, to collagenQ67675651
Nerve growth factor induces increased expression of a laminin-binding integrin in rat pheochromocytoma PC12 cellsQ68418692
Fibroblast contractility and actin organization are stimulated by microtubule inhibitorsQ69127112
Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrixQ70787146
The novel structural motif Gln795-Gln802 in the integrin beta 1C cytoplasmic domain regulates cell proliferationQ71743318
Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by CalciumQ71823689
The alpha 5 beta 1 integrin fibronectin receptor, but not the alpha 5 cytoplasmic domain, functions in an early and essential step in fibronectin matrix assemblyQ72098005
Silicone rubber substrata: a new wrinkle in the study of cell locomotionQ72128764
P433issue4
P304page(s)715-731
P577publication date1998-04-01
P1433published inMolecular Biology of the CellQ2338259
P1476titlebeta1-integrin cytoplasmic subdomains involved in dominant negative function
P478volume9

Reverse relations

cites work (P2860)
Q38609796A cell-free system to study regulation of focal adhesions and of the connected actin cytoskeleton.
Q28215390A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans
Q39683014A previously unreported function of β(1)B integrin isoform in caspase-8-dependent integrin-mediated keratinocyte death
Q30480029Alpha4beta1 integrin/ligand interaction inhibits alpha5beta1-induced stress fibers and focal adhesions via down-regulation of RhoA and induces melanoma cell migration
Q43739494Calcium signaling through the beta 2-cytoplasmic domain of LFA-1 requires intracellular elements of the T cell receptor complex
Q39226933Cross talk between beta(1) and alpha(V) integrins: beta(1) affects beta(3) mRNA stability
Q40894461Cytoplasmic domain mutants of beta1 integrin, expressed in beta 1-knockout lymphoma cells, have distinct effects on adhesion, invasion and metastasis
Q36324123Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain
Q34729632Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways
Q33608444Disruption of C-terminal cytoplasmic domain of betaPS integrin subunit has dominant negative properties in developing Drosophila.
Q36255528Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression
Q33840319Focal adhesions - the cytoskeletal connection
Q30973380Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner
Q40760846Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines
Q40512860Laminin isoforms differentially regulate adhesion, spreading, proliferation, and ERK activation of beta1 integrin-null cells
Q30536950Matrix adhesion polarizes heart progenitor induction in the invertebrate chordate Ciona intestinalis
Q44683499Modulation of Thr phosphorylation of integrin beta1 during muscle differentiation
Q24294613Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.
Q35547378Platelets with wings: the maturation of Drosophila integrin biology
Q40621534Regulation of beta1C and beta1A integrin expression in prostate carcinoma cells.
Q36322254Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.
Q28198051Signaling through focal adhesion kinase
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Q24807364Syndecans in tumor cell adhesion and signaling
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Q24680821Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin
Q41378728Yersinia enterocolitica exploits different pathways to accomplish adhesion and toxin injection into host cells.
Q37134457beta1 integrin cytoplasmic domain residues selectively modulate fibronectin matrix assembly and cell spreading through talin and Akt-1.
Q40104819beta1-Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases
Q73747994beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum
Q37080791β1 integrin is a crucial regulator of pancreatic β-cell expansion

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