| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1026082455 |
| P356 | DOI | 10.1038/379091A0 |
| P3181 | OpenCitations bibliographic resource ID | 3826838 |
| P698 | PubMed publication ID | 8538749 |
| P2093 | author name string | J C Bell | |
| S Dedhar | |||
| J Filmus | |||
| M G Coppolino | |||
| G E Hannigan | |||
| L Fitz-Gibbon | |||
| C Leung-Hagesteijn | |||
| G Radeva | |||
| P2860 | cites work | An interaction between alpha-actinin and the beta 1 integrin subunit in vitro | Q24317203 |
| Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites | Q24320277 | ||
| pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions | Q24561464 | ||
| Basic local alignment search tool | Q25938991 | ||
| The protein kinase family: conserved features and deduced phylogeny of the catalytic domains | Q27860528 | ||
| Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes | Q27860600 | ||
| Integrins: versatility, modulation, and signaling in cell adhesion | Q27860844 | ||
| A novel genetic system to detect protein-protein interactions | Q27860915 | ||
| Improved method for high efficiency transformation of intact yeast cells | Q28131608 | ||
| Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase | Q28646514 | ||
| Integrins and signal transduction pathways: the road taken | Q29547895 | ||
| Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin | Q30195270 | ||
| Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins | Q34168584 | ||
| Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information | Q35234720 | ||
| Amino acid sequence of the human fibronectin receptor | Q36217540 | ||
| Integrin cytoplasmic domains mediate inside-out signal transduction | Q36233869 | ||
| Targeted deletion of beta 1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gene expression | Q36534845 | ||
| Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity | Q37003458 | ||
| Specific alterations in the expression of alpha 3 beta 1 and alpha 6 beta 4 integrins in highly invasive and metastatic variants of human prostate carcinoma cells selected by in vitro invasion through reconstituted basement membrane | Q41529462 | ||
| Activated H-ras transforms rat intestinal epithelial cells with expression of alpha-TGF. | Q53528963 | ||
| Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16 | Q59082348 | ||
| P433 | issue | 6560 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell adhesion | Q187640 |
| P304 | page(s) | 91-6 | |
| P577 | publication date | 1996-01-04 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase | |
| P478 | volume | 379 |
| Q34727923 | A central multifunctional role of integrin-linked kinase at muscle attachment sites. |
| Q36288131 | A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans |
| Q46741501 | A conserved sequence motif in the integrin beta3 cytoplasmic domain is required for its specific interaction with beta3-endonexin |
| Q33656535 | A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. |
| Q41144341 | A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion |
| Q42277492 | A membrane proximal region of the integrin alpha5 subunit is important for its interaction with nischarin |
| Q24291182 | A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading |
| Q35910607 | A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility |
| Q38128803 | A new model for developmental neuronal death and excitatory/inhibitory balance in hippocampus |
| Q24679147 | A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction |
| Q33938365 | A novel role for integrin-linked kinase in epithelial sheet morphogenesis |
| Q38697548 | A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway |
| Q38977036 | A proteomics view on integrin-mediated adhesions |
| Q24601280 | A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation |
| Q35247596 | A vital role for Angptl3 in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro |
| Q34480626 | ADAM22, expressed in normal brain but not in high-grade gliomas, inhibits cellular proliferation via the disintegrin domain. |
| Q24603024 | ARK5 is a tumor invasion-associated factor downstream of Akt signaling |
| Q34437028 | ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma |
| Q43103951 | Adapting collagen/CNT matrix in directing hESC differentiation |
| Q37438021 | Adenovirus-mediated delivery of the human IFN-γ gene potentiates the cytotoxicity of daunorubicin against leukemic cells through downregulation of the α4β1 integrin/ILK/apoptosis pathway |
| Q42987160 | Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin |
| Q24683804 | Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail |
| Q24676556 | Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction |
| Q37677081 | Aggretin Venom Polypeptide as a Novel Anti-angiogenesis Agent by Targeting Integrin alpha2beta1. |
| Q34219471 | All-trans retinoic acid (ATRA) downregulates MMP-9 by modulating its regulatory molecules |
| Q30509545 | Allosteric modulation of beta1 integrin function induces lung tissue repair |
| Q28115147 | Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule |
| Q39984436 | Alphavbeta3 and alphavbeta5 integrins control glioma cell response to ionising radiation through ILK and RhoB. |
| Q39545316 | Alteration of integrin-dependent adhesion and signaling in EMT-like MDCK cells established through overexpression of calreticulin |
| Q40063967 | An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading. |
| Q34629975 | An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2. |
| Q42988069 | Analysis of the tetraspanin CD9-integrin alphaIIbbeta3 (GPIIb-IIIa) complex in platelet membranes and transfected cells |
| Q39028687 | Anoikis and EMT: Lethal "Liaisons" during Cancer Progression |
| Q33763531 | Anoikis disruption of focal adhesion-Akt signaling impairs renal cell carcinoma |
| Q33741854 | Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma |
| Q35956150 | Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells |
| Q40586198 | Apoptosis signaling by the novel compound 3-Cl-AHPC involves increased EGFR proteolysis and accompanying decreased phosphatidylinositol 3-kinase and AKT kinase activities. |
| Q33966952 | Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells |
| Q36241745 | Assembly and signaling of adhesion complexes |
| Q28201070 | Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen |
| Q54137235 | Association of beta 1 integrin with protein kinase activity in large detergent resistant complexes. |
| Q28208648 | Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state |
| Q45986472 | Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. |
| Q46438962 | Balance between apoptosis or survival induced by changes in extracellular-matrix composition in human mesangial cells: a key role for ILK-NFκB pathway |
| Q41089035 | Beta 1 integrin is essential for teratoma growth and angiogenesis |
| Q34356308 | Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer |
| Q42100954 | Beta1-integrin signaling is essential for lens fiber survival |
| Q33845332 | Bi-directional signal transduction by integrin receptors |
| Q24317468 | Binding of the chemokine SLC/CCL21 to its receptor CCR7 increases adhesive properties of human mesangial cells |
| Q35065294 | Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase. |
| Q38078237 | Biomarkers for predicting future metastasis of human gastrointestinal tumors. |
| Q43996515 | C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes |
| Q84199260 | CCN1 induces a reversible epithelial-mesenchymal transition in gastric epithelial cells |
| Q38332129 | CCN3 increases BMP-4 expression and bone mineralization in osteoblasts |
| Q41187983 | CD44 phosphorylation regulates melanoma cell and fibroblast migration on, but not attachment to, a hyaluronan substratum. |
| Q34720176 | CTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasia |
| Q40675042 | Ca2+-dependent localization of integrin-linked kinase to cell junctions in differentiating keratinocytes |
| Q30661698 | Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase |
| Q31705382 | Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function. |
| Q34160361 | Cardiac Z-disc signaling network |
| Q36914463 | Cell adhesion - spreading frontiers, intricate insights. |
| Q28571378 | Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways |
| Q40643553 | Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro |
| Q28583390 | Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase.c-Src complex |
| Q33959947 | Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner |
| Q38075788 | Cell-matrix adhesion of podocytes in physiology and disease |
| Q28138260 | Cell-substrate interactions and signaling through ILK |
| Q54557709 | Cellular repressor of E1A-stimulated genes regulates vascular endothelial cell migration by the ILK/AKT/mTOR/VEGF(165) signaling pathway. |
| Q36649005 | Characterisation of integrin-linked kinase signalling in sporadic human colon cancer |
| Q28217164 | Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration |
| Q36373441 | Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis |
| Q34480718 | Chondrocyte-matrix attachment complexes mediate survival and differentiation |
| Q35104008 | Clinicopathological significance of stromal variables: angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas |
| Q24300836 | Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I |
| Q22254461 | Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation |
| Q44755141 | Collagen I upregulates extracellular matrix gene expression and secretion of TGF-beta 1 by cultured human mesangial cells |
| Q40684571 | Conditional overexpression of connective tissue growth factor disrupts postnatal lung development |
| Q37118092 | Contributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis. |
| Q34048129 | Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor development |
| Q38531654 | Costamere proteins and their involvement in myopathic processes. |
| Q40190677 | Critical involvement of ILK in TGFbeta1-stimulated invasion/migration of human ovarian cancer cells is associated with urokinase plasminogen activator system |
| Q37376161 | Critical role of integrin-linked kinase in granule cell precursor proliferation and cerebellar development |
| Q36323239 | Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling |
| Q33719178 | Culture of K562 human myeloid leukemia cells in presence of fibronectin expresses and secretes MMP-9 in serum-free culture medium. |
| Q39658831 | Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity |
| Q33662882 | Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin |
| Q33597877 | Cytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cells |
| Q37631255 | Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice |
| Q33835741 | Diabetes induces changes in ILK, PINCH and components of related pathways in the spinal cord of rats |
| Q28143849 | Diacylglycerol kinase zeta in hypothalamus interacts with long form leptin receptor. Relation to dietary fat and body weight regulation |
| Q34264538 | Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation |
| Q24652710 | Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits |
| Q40801444 | Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins |
| Q34729632 | Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways |
| Q37401876 | Differentiation and cancer in the mammary gland: shedding light on an old dichotomy. |
| Q48268973 | Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex |
| Q44884877 | Distinct kinases are involved in contraction of cat esophageal and lower esophageal sphincter smooth muscles |
| Q57998264 | Divalent Cations Differentially Regulate Integrin αIIbCytoplasmic Tail Binding to β3and to Calcium- and Integrin-binding Protein |
| Q28581884 | Dp71f modulates GSK3-beta recruitment to the beta1-integrin adhesion complex |
| Q36379951 | Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane |
| Q35607185 | Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome |
| Q46121276 | Dysregulation of PINCH signaling in mesial temporal epilepsy |
| Q28189965 | Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis |
| Q79190003 | ELMO1 increases expression of extracellular matrix proteins and inhibits cell adhesion to ECMs |
| Q35908095 | Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway |
| Q33800785 | Effect of Huayu Tongluo Herbs on Reduction of Proteinuria via Inhibition of Wnt/β-Catenin Signaling Pathway in Diabetic Rats |
| Q46814261 | Effect of uraemia on endothelial cell damage is mediated by the integrin linked kinase pathway |
| Q36520213 | Effects of integrin α5β1 on the proliferation and migration of human aortic vascular smooth muscle cells |
| Q45309205 | Effects of integrin-linked kinase on human corpus cavernosum smooth muscle cell cytoskeletal organisation |
| Q36241222 | Elevated expression levels of ANXA11, integrins β3 and α3, and TNF-α contribute to a candidate proteomic signature in urine for kidney allograft rejection |
| Q41469750 | Emerging paradigms of integrin ligand binding and activation |
| Q42321188 | Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways |
| Q34568941 | Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma |
| Q37549516 | Emodin Inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer Cells via ILK/GSK-3β/Slug Signaling Pathway |
| Q41169675 | En bloc transfer of extracellular matrix in vitro |
| Q38689489 | Enhanced Ca2+Entry and Tyrosine Phosphorylation Mediate Nanostructure-Induced Endothelial Proliferation. |
| Q24681057 | Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein |
| Q39736489 | Entry of Neisseria meningitidis into mammalian cells requires the Src family protein tyrosine kinases |
| Q40229398 | Epigenetic regulation of integrin-linked kinase expression depending on adhesion of gastric carcinoma cells |
| Q38841415 | Epithelial cell extrusion: Pathways and pathologies. |
| Q37133680 | Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction |
| Q47707488 | Expression and function of beta 1 integrins on human eosinophils |
| Q37732589 | Expression and role of integrin-linked kinase and collagen IV in human renal allografts with interstitial fibrosis and tubular atrophy |
| Q46813503 | Expression of PINCH protein in gliomas and its clinicopathological significance |
| Q33723882 | Expression of integrin-linked kinase improves cardiac function in a swine model of myocardial infarction |
| Q82771174 | Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: correlation with E-cadherin expression, tumor microvessel density and clinical outcome |
| Q39978242 | Expression of integrin-linked kinase is increased in differentiated cells |
| Q42459989 | Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2. |
| Q28628647 | Extracellular matrix and integrin signalling: the shape of things to come |
| Q42439285 | Extracellular matrix proteins induce changes in intracellular calcium and cyclic AMP signalling systems in cultured human keratinocytes |
| Q34103396 | Extracellular matrix signaling: integration of form and function in normal and malignant cells |
| Q80818064 | Extracellular matrix: the central regulator of cell and tissue homeostasis |
| Q42150675 | Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing |
| Q24309146 | Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction |
| Q43154325 | Fish oil inhibits human lung carcinoma cell growth by suppressing integrin-linked kinase |
| Q37452962 | Focal adhesion complex proteins in epidermis and squamous cell carcinoma. |
| Q42784215 | Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype |
| Q36117925 | Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics |
| Q74179869 | Functional cooperation of beta1-integrins and members of the Ig superfamily in neurite outgrowth induction |
| Q36922587 | Functional implications of tetraspanin proteins in cancer biology |
| Q45871063 | Gene modification with integrin-linked kinase improves function of endothelial progenitor cells in pre-eclampsia in vitro |
| Q36823682 | Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma |
| Q37101121 | HAX1 deletion impairs BCR internalization and leads to delayed BCR-mediated apoptosis |
| Q57614242 | HAX1 deletion impairs BCR internalization and leads to delayed BCR-mediated apoptosis |
| Q41761709 | HGF accelerates wound healing by promoting the dedifferentiation of epidermal cells through β1-integrin/ILK pathway |
| Q48596950 | HMGA1 participates in MHCC97H cell proliferation and invasion through the ILK/Akt/GSK3β signaling pathway |
| Q44930591 | Hepatocyte survival depends on beta1-integrin-mediated attachment of hepatocytes to hepatic extracellular matrix |
| Q35583857 | High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma. |
| Q37875475 | How integrins control mammary epithelial differentiation: a possible role for the ILK-PINCH-Parvin complex |
| Q57794614 | Human Bronchial Epithelial Cells Inhibit Aspergillus fumigatus Germination of Extracellular Conidia via FleA Recognition |
| Q57051343 | Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia |
| Q24308783 | ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin |
| Q38739650 | ILK and cytoskeletal architecture: an important determinant of AQP2 recycling and subsequent entry into the exocytotic pathway |
| Q50286389 | ILK interacts with beta-1 integrin |
| Q23924060 | ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling |
| Q34597585 | ILK mediates the effects of strain on intestinal epithelial wound closure |
| Q90448008 | ILK predicts the efficacy of chemoradiotherapy and the prognosis of patients with esophageal squamous cell carcinoma |
| Q36403372 | ILK, PINCH and parvin: the tIPP of integrin signalling |
| Q39824675 | ILK-PI3K/AKT pathway participates in cutaneous wound contraction by regulating fibroblast migration and differentiation to myofibroblast |
| Q27001701 | ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling |
| Q38122232 | ILK: a pseudokinase with a unique function in the integrin-actin linkage |
| Q34301995 | ILKAP regulates ILK signaling and inhibits anchorage-independent growth |
| Q24329209 | Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase |
| Q33985104 | Identification and characterization of a novel integrin-linked kinase inhibitor |
| Q60915245 | Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth |
| Q37242557 | Identification of ILK as a novel therapeutic target for acute and chronic myeloid leukemia |
| Q28203144 | Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury |
| Q28116142 | Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain |
| Q28213843 | Identification of a novel interaction between integrin beta1 and 14-3-3beta |
| Q44101117 | Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1. |
| Q40689467 | Identification of a signal transduction pathway that regulates MMP-9 mRNA expression in glomerular injury |
| Q28291781 | Identification of an interaction between the m-band protein skelemin and beta-integrin subunits. Colocalization of a skelemin-like protein with beta1- and beta3-integrins in non-muscle cells |
| Q33852653 | Impact of PINCH expression on survival in colorectal cancer patients |
| Q42681450 | In Silico Protein Interaction Analysis Using the Global Proteome Machine Database |
| Q35832011 | In vitro analysis of integrin expression in stem cells from bone marrow and cord blood during chondrogenic differentiation |
| Q39971911 | Increase of integrin-linked kinase activity in cultured podocytes upon stimulation with plasma from patients with recurrent FSGS. |
| Q34163462 | Increased expression of integrin-linked kinase improves cardiac function and decreases mortality in dilated cardiomyopathy model of rats |
| Q24795806 | Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer |
| Q34137296 | Induction of apoptosis by stomach cancer-associated protein-tyrosine phosphatase-1. |
| Q98195632 | Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons |
| Q40443893 | Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth. |
| Q43539828 | Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells |
| Q28344025 | Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells |
| Q37330584 | Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis |
| Q40777998 | Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis |
| Q34145575 | Inhibition of protein kinase B/Akt. implications for cancer therapy |
| Q37733714 | Insights into the Structure, Function, and Ion-Mediated Signaling Pathways Transduced by Plant Integrin-Linked Kinases. |
| Q92969956 | Insulin attenuates apoptosis in neuronal cells by an integrin-linked kinase-dependent mechanism |
| Q42153207 | Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice |
| Q53474736 | Insulin stimulates integrin-linked kinase in UMR-106 cells: potential role of heparan sulfate on syndecan-1. |
| Q35807732 | Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network |
| Q33762935 | Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. |
| Q77203120 | Integrin affinity modulation |
| Q58749213 | Integrin and microtubule crosstalk in the regulation of cellular processes |
| Q77565695 | Integrin associated proteins |
| Q38717409 | Integrin beta and receptor for activated protein kinase C are involved in the cell entry of Bombyx mori cypovirus |
| Q46376510 | Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins. |
| Q41869916 | Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus |
| Q41663568 | Integrin cytoplasmic domains as connectors to the cell's signal transduction apparatus |
| Q40924688 | Integrin cytoplasmic interactions and bidirectional transmembrane signalling |
| Q26823123 | Integrin cytoplasmic tail interactions |
| Q37406751 | Integrin linked kinase (ILK) expression and function in vascular smooth muscle cells |
| Q51087956 | Integrin linked kinase regulates syncytialization of BeWo trophoblast cells. |
| Q35201088 | Integrin receptors: the dynamic modulators of endometrial function |
| Q34746946 | Integrin signaling and cell growth control |
| Q35676234 | Integrin signaling and mammary cell function |
| Q35547365 | Integrin signaling to the actin cytoskeleton. |
| Q41663575 | Integrin signaling: building connections beyond the focal contact? |
| Q41612555 | Integrin signaling: specificity and control of cell survival and cell cycle progression |
| Q35875611 | Integrin signalling and the cellular response to ionizing radiation. |
| Q36465070 | Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish. |
| Q90124520 | Integrin α9 depletion promotes β-catenin degradation to suppress triple-negative breast cancer tumor growth and metastasis |
| Q37665359 | Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-AKT signaling following MEK inhibition in metastatic triple negative breast cancer |
| Q37592138 | Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle |
| Q48263768 | Integrin-Linked Kinase Expression in Myeloid Cells Promotes Inflammatory Signaling during Experimental Colitis. |
| Q92383113 | Integrin-Linked Kinase Is Involved In the Proliferation and Invasion of Esophageal Squamous Cell Carcinoma |
| Q48024743 | Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance |
| Q50993502 | Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease. |
| Q36735258 | Integrin-Linked Kinase: It's Role in the Vascular System |
| Q40500279 | Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8. |
| Q34429805 | Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes |
| Q28212649 | Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions |
| Q43786778 | Integrin-linked kinase (ILK) expression correlates with tumor severity in clear cell renal carcinoma |
| Q39835492 | Integrin-linked kinase (ILK) in pulmonary fibrosis |
| Q28585627 | Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation |
| Q44121201 | Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF). |
| Q34047231 | Integrin-linked kinase (ILK): a "hot" therapeutic target |
| Q33688041 | Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling. |
| Q37825335 | Integrin-linked kinase 1: role in hormonal cancer progression |
| Q40330932 | Integrin-linked kinase activity is associated with interleukin-1 alpha-induced progressive behavior of pancreatic cancer and poor patient survival |
| Q37225450 | Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells |
| Q53675615 | Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX. |
| Q36435777 | Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models |
| Q37225025 | Integrin-linked kinase can facilitate syncytialization and hormonal differentiation of the human trophoblast-derived BeWo cell line |
| Q35950088 | Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase |
| Q31010256 | Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells |
| Q37208161 | Integrin-linked kinase deletion from mouse cortex results in cortical lamination defects resembling cobblestone lissencephaly. |
| Q42025988 | Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. |
| Q33533661 | Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration. |
| Q43122600 | Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. |
| Q38268065 | Integrin-linked kinase in gastric cancer cell attachment, invasion and tumor growth |
| Q28581550 | Integrin-linked kinase in the vascular smooth muscle cell response to injury |
| Q24300849 | Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells |
| Q28749480 | Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation |
| Q28567387 | Integrin-linked kinase is a positive mediator of L6 myoblast differentiation |
| Q28261429 | Integrin-linked kinase is an adaptor with essential functions during mouse development |
| Q40324201 | Integrin-linked kinase is an essential link between integrins and uptake of bacterial pathogens by epithelial cells. |
| Q43011923 | Integrin-linked kinase is involved in matrix-induced hepatocyte differentiation |
| Q30480583 | Integrin-linked kinase is required for epidermal and hair follicle morphogenesis |
| Q28587844 | Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system |
| Q38910981 | Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum |
| Q24655829 | Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization |
| Q28589224 | Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis |
| Q34283506 | Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation |
| Q33828741 | Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma |
| Q40771629 | Integrin-linked kinase regulates chondrocyte shape and proliferation |
| Q37493087 | Integrin-linked kinase regulates endothelial cell survival and vascular development. |
| Q40766267 | Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner |
| Q35005925 | Integrin-linked kinase regulates integrin signaling in human trabecular meshwork cells. |
| Q27321017 | Integrin-linked kinase regulates interphase and mitotic microtubule dynamics |
| Q39600634 | Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway. |
| Q40317325 | Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells |
| Q36890811 | Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells |
| Q47074406 | Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism |
| Q50933796 | Integrin-linked kinase regulates process extension in oligodendrocytes via control of actin cytoskeletal dynamics. |
| Q37018280 | Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. |
| Q35180008 | Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi |
| Q42850406 | Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart |
| Q34792920 | Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties |
| Q42727619 | Integrin-linked kinase: a Scaffold protein unique among its ilk. |
| Q35998768 | Integrin-linked kinase: a cancer therapeutic target unique among its ILK. |
| Q37878251 | Integrin-linked kinase: not so 'pseudo' after all. |
| Q41067663 | Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity |
| Q42810800 | Integrin-mediated activation of MEK and mitogen-activated protein kinase is independent of Ras [corrected]. |
| Q27316196 | Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane |
| Q77725298 | Integrins and T helper cell activation |
| Q41612562 | Integrins and anoikis |
| Q41238988 | Integrins and cancer |
| Q41612577 | Integrins and inside-out signal transduction: converging signals from PKC and PIP3. |
| Q30575418 | Integrins and integrin-associated proteins in the cardiac myocyte. |
| Q41694564 | Integrins in morphogenesis and signaling |
| Q33850089 | Integrins: a role as cell signalling molecules |
| Q34990955 | Interaction of integrin-linked kinase and miniature chromosome maintenance 7-mediating integrin {alpha}7 induced cell growth suppression |
| Q24307933 | Interaction of integrin-linked kinase with the kidney chloride/bicarbonate exchanger, kAE1 |
| Q40985640 | Interaction of the integrin beta1 cytoplasmic domain with ICAP-1 protein |
| Q37038045 | Interactions of airway smooth muscle cells with their tissue matrix: implications for contraction |
| Q52645434 | Interference with the contractile machinery of the fibroblastic chondrocyte cytoskeleton induces re-expression of the cartilage phenotype through involvement of PI3K, PKC and MAPKs. |
| Q24322828 | Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS |
| Q36117238 | Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways. |
| Q24815934 | Involvement of integrin-linked kinase in capillary/tube-like network formation of human vascular endothelial cells |
| Q51204980 | Isolated effect of material stiffness on valvular interstitial cell differentiation. |
| Q37209242 | JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma |
| Q84947040 | Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells |
| Q28509694 | Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development |
| Q39628047 | Krüppel-like factor 5 controls keratinocyte migration via the integrin-linked kinase |
| Q35987858 | LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration. |
| Q38657513 | Leptospira interrogans causes quantitative and morphological disturbances in adherens junctions and other biological groups of proteins in human endothelial cells |
| Q34426260 | Leukocyte adhesion--structure and function of human leukocyte beta2-integrins and their cellular ligands |
| Q41481792 | Ligand binding and affinity modulation of integrins |
| Q40956410 | Ligand-specific, transient interaction between integrins and calreticulin during cell adhesion to extracellular matrix proteins is dependent upon phosphorylation/dephosphorylation events |
| Q64242046 | Liver X Receptor/Retinoid X Receptor Pathway Plays a Regulatory Role in Pacing-Induced Cardiomyopathy |
| Q38481151 | Loss of integrin linked kinase from mouse hepatocytes in vitro and in vivo results in apoptosis and hepatitis. |
| Q33850055 | Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load |
| Q43796891 | Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. |
| Q35636588 | Manipulation of kinase signaling by bacterial pathogens |
| Q34186534 | Maspin regulates endothelial cell adhesion and migration through an integrin signaling pathway |
| Q46046763 | Matrix metalloproteinase-9 deficiency attenuates diabetic nephropathy by modulation of podocyte functions and dedifferentiation |
| Q36702544 | Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis |
| Q34632608 | Mechanosensing and Regulation of Cardiac Function |
| Q26849684 | Mechanosensitivity and compositional dynamics of cell-matrix adhesions |
| Q22010596 | Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain |
| Q42378473 | MicroRNA-542-3p inhibits oral squamous cell carcinoma progression by inhibiting ILK/TGF-β1/Smad2/3 signaling |
| Q34210068 | MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression |
| Q38415772 | MicroRNAs as the fine-tuners of Src oncogenic signalling |
| Q28610904 | Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation |
| Q44683499 | Modulation of Thr phosphorylation of integrin beta1 during muscle differentiation |
| Q40262829 | Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells |
| Q33771748 | Modulation of cellular apoptotic potential: contributions to oncogenesis |
| Q40327085 | Modulation of gene expression in MHCC97 cells by interferon alpha |
| Q24291184 | Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1. |
| Q35016166 | Modulation of integrin-linked kinase (ILK) expression in human oesophageal squamous cell carcinoma cell lines by the EGF and TGFbeta1 growth factors |
| Q34073868 | Modulation of microvascular smooth muscle adhesion and mechanotransduction by integrin-linked kinase |
| Q36512542 | Modulation of response to tumor therapies by the extracellular matrix |
| Q35620884 | Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. |
| Q28210618 | Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin |
| Q34100459 | Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization |
| Q36242102 | Molecular mechanism of apoptosis induced by mechanical forces |
| Q37903927 | Molecular mechanism of inside-out integrin regulation |
| Q37481044 | Molecular mechanisms of mechanosensing in muscle development. |
| Q36865595 | Multifaceted roles of integrins in breast cancer metastasis |
| Q28634029 | Multimerization of the cytoplasmic domain of syndecan-4 is required for its ability to activate protein kinase C |
| Q34264905 | Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling |
| Q24655497 | Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways |
| Q37783442 | New Insights into the Regulation of Ion Channels by Integrins |
| Q24597466 | New insights into the role of RNase L in innate immunity |
| Q58115566 | Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion |
| Q38742565 | Novel 3-D cell culture system for in vitro evaluation of anticancer drugs under anchorage-independent conditions |
| Q38974336 | Opportunities to Target Specific Contractile Abnormalities with Smooth Muscle Protein Kinase Inhibitors |
| Q37716265 | Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption. |
| Q37455849 | Osteopontin induces beta-catenin signaling through activation of Akt in prostate cancer cells |
| Q50853594 | Overexpression of ILK1 in breast cancer associates with poor prognosis. |
| Q34786395 | Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury |
| Q38400105 | Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer |
| Q39094498 | Overexpression of integrin-linked kinase (ILK) promotes glioma cell invasion and migration and down-regulates E-cadherin via the NF-κB pathway |
| Q42252800 | Overexpression of integrin-linked kinase promotes lung cancer cell migration and invasion via NF-κB-mediated upregulation of matrix metalloproteinase-9. |
| Q40449732 | PDMS Elastic Micropost Arrays for Studying Vascular Smooth Muscle Cells. |
| Q28208706 | PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival |
| Q28586847 | PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes |
| Q33968025 | PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha |
| Q28589673 | PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions |
| Q27691415 | PINCH: More than just an adaptor protein in cellular response |
| Q36530322 | PP2C family members play key roles in regulation of cell survival and apoptosis |
| Q37012318 | Particularly interesting cysteine- and histidine-rich protein in cardiac development and remodeling |
| Q36421428 | Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation |
| Q37398880 | Peripheral sensory axon growth: from receptor binding to cellular signaling |
| Q37369202 | Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology |
| Q40040300 | Pharmacological inhibition of EGFR tyrosine kinase affects ILK-mediated cellular radiosensitization in vitro |
| Q26786112 | Phenotypic and Genotypic Characteristics of Small Colony Variants and Their Role in Chronic Infection |
| Q28272724 | Phosphoinositide 3-OH kinase activates the beta2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1 |
| Q24682825 | Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase |
| Q24305936 | Phosphorylation and interaction of myopodin by integrin-link kinase lead to suppression of cell growth and motility in prostate cancer cells |
| Q58169387 | Phosphorylation of ser246residue in integrin‐linked kinase 1 by serum‐ and glucocorticoid‐induced kinase 1 is required to form a protein‐protein complex with 14–3–3 |
| Q41827565 | Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase |
| Q38940494 | Podocyte-actin dynamics in health and disease |
| Q35564801 | Positional Control of Cell Fate Through Joint Integrin/Receptor Protein Kinase Signaling |
| Q34153751 | Possible role of ILK-affixin complex in integrin-cytoskeleton linkage during platelet aggregation. |
| Q38698820 | Post-translational modification of the membrane type 1 matrix metalloproteinase (MT1-MMP) cytoplasmic tail impacts ovarian cancer multicellular aggregate dynamics |
| Q42092696 | Postnatal Loss of Kindlin-2 Leads to Progressive Heart Failure. |
| Q38112468 | Preclinical models of multiple myeloma: a critical appraisal |
| Q33589341 | Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation. |
| Q31059291 | Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1. |
| Q34189344 | Protein kinase B (PKB/Akt)--a key regulator of glucose transport? |
| Q36060746 | Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog |
| Q44942869 | Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling |
| Q73956117 | Proteolytic cleavage of the beta1 subunit of platelet alpha2beta1 integrin by the metalloproteinase jararhagin compromises collagen-stimulated phosphorylation of pp72 |
| Q52719964 | Proteomic profiling of human cancer pseudopodia for the identification of anti-metastatic drug candidates. |
| Q28485871 | Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex |
| Q74316491 | Purification of integrins and characterization of integrin-associated proteins |
| Q40696698 | Puromycin insensitive leucyl-specific aminopeptidase (PILSAP) is involved in the activation of endothelial integrins |
| Q73838583 | Putative mechanism through which N-cadherin-mediated cell contact maintains calcium homeostasis and thereby prevents ovarian cells from undergoing apoptosis |
| Q37277114 | QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatmen |
| Q37324457 | RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance |
| Q28566512 | Rat seminiferous epithelium contains a unique junction (Ectoplasmic specialization) with signaling properties both of cell/cell and cell/matrix junctions |
| Q34182228 | Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival. |
| Q36755844 | Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology |
| Q80359557 | Reciprocally interacting domains of protein phosphatase 1 and focal adhesion kinase |
| Q40632635 | Reduced cell adhesion during mitosis by threonine phosphorylation of β1 integrin |
| Q28591949 | Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes |
| Q28141939 | Regulation of LEF-1/TCF transcription factors by Wnt and other signals |
| Q34638760 | Regulation of adhesive interaction between podocytes and glomerular basement membrane |
| Q39999153 | Regulation of cell-matrix contacts and beta-catenin signaling in VSMC by integrin-linked kinase: implications for intimal thickening |
| Q41881846 | Regulation of interleukin 1 signalling through integrin binding and actin reorganization: disparate effects on NF-kappaB and stress kinase pathways. |
| Q41758442 | Regulation of neurite outgrowth by integrin activation. |
| Q38815948 | Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells. |
| Q53630806 | Regulation of protein phosphatase 2A-mediated recruitment of IQGAP1 to beta1 integrin by EGF through activation of Ca2+/calmodulin-dependent protein kinase II. |
| Q36328536 | Regulation of the cell cycle by focal adhesion kinase |
| Q44746334 | Regulation of tumor angiogenesis by integrin-linked kinase (ILK). |
| Q37568489 | Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease |
| Q97646299 | Research Progress on the Pathological Mechanisms of Podocytes in Diabetic Nephropathy |
| Q26741077 | Research advances on structure and biological functions of integrins |
| Q77716515 | Role of beta1 integrins in adhesion and invasion of hepatocellular carcinoma cells |
| Q38218126 | Role of integrin alpha4 in drug resistance of leukemia |
| Q28564942 | Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth |
| Q93128943 | Role of integrin-linked kinase in the hypoxia-induced phenotypic transition of pulmonary artery smooth muscle cells: Implications for hypoxic pulmonary hypertension |
| Q28572867 | Role of the integrin-linked kinase (ILK) in determining neuronal polarity |
| Q28567124 | Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy |
| Q37489705 | Role of the oligodendroglial cytoskeleton in differentiation and myelination |
| Q37608582 | Role of the sarcomeric Z-disc in the pathogenesis of cardiomyopathy |
| Q39107450 | Select cytoplasmic and membrane proteins increase the percentage of immobile integrins but do not affect the average diffusion coefficient of mobile integrins |
| Q60601167 | Selective regulation of p38β protein and signaling by integrin-linked kinase mediates bladder cancer cell migration |
| Q36888890 | Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin |
| Q36749420 | Serum concentration of integrin-linked kinase in malignant pleural mesothelioma and after asbestos exposure |
| Q35750599 | Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells |
| Q73538445 | Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin alpha(2)beta(1) |
| Q38945219 | Signaling via PINCH: Functions, binding partners and implications in human diseases |
| Q61808060 | Significance of integrin-linked kinase (ILK) in tumorigenesis and its potential implication as a biomarker and therapeutic target for human cancer |
| Q33916456 | Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy |
| Q28216833 | Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression |
| Q24316487 | Spatial and temporal expression of the beta1D integrin during mouse development |
| Q34286961 | Spatial coordination of kindlin-2 with talin head domain in interaction with integrin β cytoplasmic tails |
| Q28348345 | Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1 |
| Q39552518 | Streptococcus pyogenes M49 plasminogen/plasmin binding facilitates keratinocyte invasion via integrin-integrin-linked kinase (ILK) pathways and protects from macrophage killing |
| Q33639654 | Structural and mechanical functions of integrins |
| Q24295139 | Structural basis for paxillin binding and focal adhesion targeting of β-parvin |
| Q24312707 | Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase |
| Q43793793 | Structure and control of a cell-cell adhesion complex associated with spermiation in rat seminiferous epithelium |
| Q52532836 | Structure and function of phosphoinositide 3-kinases. |
| Q77135333 | Stuck on the ECM |
| Q27330531 | Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin |
| Q33718142 | Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance |
| Q41866389 | Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure |
| Q34230960 | Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival |
| Q37691830 | Targeting anoikis resistance in prostate cancer metastasis |
| Q37725588 | Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells. |
| Q35101834 | Tetraspanin proteins as organisers of membrane microdomains and signalling complexes. |
| Q36816899 | The C. elegans dense body: anchoring and signaling structure of the muscle |
| Q33668166 | The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! |
| Q41349703 | The Integrin-Mediated ILK-Parvin-αPix Signaling Axis Controls Differentiation in Mammary Epithelial Cells |
| Q22254650 | The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes |
| Q24554520 | The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells |
| Q41715749 | The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity |
| Q58058035 | The Molecular Anatomy of Integrins |
| Q39863533 | The NPIY motif in the integrin beta1 tail dictates the requirement for talin-1 in outside-in signaling |
| Q27646573 | The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions |
| Q51013229 | The RGD sequence present in IGFBP-2 is required for reduced glucose clearance after oral glucose administration in female transgenic mice. |
| Q28248964 | The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions |
| Q24302005 | The Roles of Two Distinct Regions of PINCH-1 in the Regulation of Cell Attachment and Spreading |
| Q39988441 | The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells |
| Q36342506 | The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane |
| Q45823378 | The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling. |
| Q47297232 | The binding interface of kindlin-2 and ILK involves Asp344/Asp352/Thr356 in kindlin-2 and Arg243/Arg334 in ILK. |
| Q44884873 | The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation |
| Q36476684 | The crystal structure of calcium- and integrin-binding protein 1: insights into redox regulated functions |
| Q29615176 | The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway |
| Q28363377 | The distribution and regulation of integrin-linked kinase in normal and diabetic kidneys |
| Q37855124 | The extracellular matrix dimension of skeletal muscle development |
| Q24314888 | The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor |
| Q22011190 | The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells |
| Q39586214 | The importance of integrin-linked kinase in the regulation of bladder cancer invasion |
| Q38263509 | The importance of podocyte adhesion for a healthy glomerulus |
| Q53845753 | The inhibitory effects of endostatin on endothelial cells are modulated by extracellular matrix. |
| Q40837811 | The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9). |
| Q24676735 | The integrin-actin connection, an eternal love affair |
| Q40860408 | The integrin-linked kinase (ILK) suppresses anoikis |
| Q35078592 | The integrin-linked kinase-PINCH-parvin complex supports integrin αIIbβ3 activation |
| Q33912945 | The leukocyte integrins |
| Q71118216 | The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan |
| Q26825105 | The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration |
| Q36325617 | The parvins |
| Q28209665 | The paxillin LD motifs |
| Q36745379 | The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer |
| Q33961247 | The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis |
| Q52581709 | The platelet integrin alpha IIbbeta 3 has an endogenous thiol isomerase activity. |
| Q40526832 | The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha 2 beta 1. |
| Q38181120 | The role of integrins in the development and homeostasis of the epidermis and skin appendages |
| Q36328735 | The roles of integrin-linked kinase in the regulation of myogenic differentiation |
| Q34485166 | The sarcomeric Z-disc: a nodal point in signalling and disease |
| Q24310652 | The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin |
| Q42525702 | The signaling adapter protein PINCH is up-regulated in the stroma of common cancers, notably at invasive edges |
| Q33489630 | The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck |
| Q73074246 | The snake venom disintegrin salmosin induces apoptosis by disassembly of focal adhesions in bovine capillary endothelial cells |
| Q24324678 | The structural basis of integrin-linked kinase-PINCH interactions |
| Q93275066 | Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish |
| Q37628723 | There's something about ILK. |
| Q33991101 | Thy-1-integrin alphav beta5 interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-beta1 activation and myofibroblast differentiation |
| Q46340962 | Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment |
| Q40115872 | Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts. |
| Q33566534 | Ultrasound microbubble-mediated delivery of integrin-linked kinase gene improves endothelial progenitor cells dysfunction in pre-eclampsia |
| Q92800229 | Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies |
| Q80676334 | Up-regulation of integrin-linked kinase in the streptozotocin-induced diabetic rat retina |
| Q42830760 | Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway |
| Q37590239 | Upregulation of c-mip is closely related to podocyte dysfunction in membranous nephropathy |
| Q37662617 | Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue. |
| Q28306860 | VLA-4-mediated interactions between normal human hematopoietic progenitors and stromal cells |
| Q37944602 | Vascular smooth muscle myosin light chain diphosphorylation: mechanism, function, and pathological implications |
| Q36962844 | WISP-1 promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells |
| Q40723420 | Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells |
| Q34774115 | Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex |
| Q53808172 | [New strategies for tissue replacement in the head and neck region]. |
| Q44365696 | alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells |
| Q43977769 | beta 1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway |
| Q38321983 | beta(1) integrin binds the 16-kDa subunit of vacuolar H(+)-ATPase at a site important for human papillomavirus E5 and platelet-derived growth factor signaling |
| Q36863689 | beta1-integrin cytoplasmic subdomains involved in dominant negative function |
| Q48717796 | beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury. |
| Q39608009 | c-Jun N-terminal kinase is involved in the regulation of proliferation and apoptosis by integrin-linked kinase in human retinoblastoma cells |
| Q33903097 | c-erbB2-induced disruption of matrix adhesion and morphogenesis reveals a novel role for protein kinase B as a negative regulator of alpha(2)beta(1) integrin function |
| Q28756293 | kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin |
| Q35312201 | mda-9/Syntenin protein positively regulates the activation of Akt protein by facilitating integrin-linked kinase adaptor function during adhesion to type I collagen |
| Q53355086 | ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation. |
| Q58214831 | α-Actinin-4 Is Required for Normal Podocyte Adhesion |
| Q27309279 | αV-integrins are required for mechanotransduction in MDCK epithelial cells |
| Q41122817 | β1 integrin: an emerging player in the modulation of tumorigenesis and response to therapy |
| Q34011023 | β1-Integrin and integrin linked kinase regulate astrocytic differentiation of neural stem cells |
| Q47433912 | β1-integrin restricts astrocytic differentiation of adult hippocampal neural stem cells. |
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