scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1027098741 |
P356 | DOI | 10.1038/SJ.ONC.1203288 |
P698 | PubMed publication ID | 10644997 |
P5875 | ResearchGate publication ID | 12669552 |
P2093 | author name string | Roth RA | |
Tomlinson MG | |||
Bolen JB | |||
Nakatani K | |||
Herbst R | |||
Morimoto AM | |||
P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain | Q22009089 | ||
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase | Q24314398 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase | Q24682825 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Regulation of phosphoinositide-specific phospholipase C isozymes | Q28240477 | ||
PTEN1 is frequently mutated in primary endometrial carcinomas | Q28250937 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins | Q28569131 | ||
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway | Q33599964 | ||
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. | Q33869038 | ||
The akt kinase: molecular determinants of oncogenicity | Q36758478 | ||
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis. | Q40939773 | ||
Inhibition of phospholipase C-gamma1 activation blocks glioma cell motility and invasion of fetal rat brain aggregates | Q40968600 | ||
Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase | Q40972780 | ||
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway | Q40986827 | ||
Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. | Q41063499 | ||
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity | Q41067663 | ||
Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression | Q41109515 | ||
Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line | Q41491473 | ||
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. | Q42824933 | ||
Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway | Q49111454 | ||
Lipid-Regulated Kinases: Some Common Themes at Last | Q57903715 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling | Q77195331 | ||
Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction | Q77686452 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 200-209 | |
P577 | publication date | 2000-01-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity | |
P478 | volume | 19 |
Q34629975 | An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2. |
Q28138260 | Cell-substrate interactions and signaling through ILK |
Q22254461 | Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation |
Q48158087 | Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines. |
Q36379951 | Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane |
Q34301995 | ILKAP regulates ILK signaling and inhibits anchorage-independent growth |
Q33762935 | Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. |
Q35676234 | Integrin signaling and mammary cell function |
Q34429805 | Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes |
Q34047231 | Integrin-linked kinase (ILK): a "hot" therapeutic target |
Q28567387 | Integrin-linked kinase is a positive mediator of L6 myoblast differentiation |
Q40766267 | Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner |
Q34792920 | Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties |
Q35998768 | Integrin-linked kinase: a cancer therapeutic target unique among its ILK. |
Q37409706 | MDA-9/syntenin is a key regulator of glioma pathogenesis |
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Q34283477 | Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. |
Q24291184 | Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1. |
Q36713508 | PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in glioma |
Q38183283 | Role of Akt in human malignant glioma: from oncogenesis to tumor aggressiveness. |
Q40837811 | The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9). |
Q40860408 | The integrin-linked kinase (ILK) suppresses anoikis |
Q30165214 | The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration. |
Q28645742 | The protein kinase B/Akt signalling pathway in human malignancy |
Q29547402 | The versatility and universality of calcium signalling |
Q37628723 | There's something about ILK. |
Q36364880 | Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation |
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