Manipulation of kinase signaling by bacterial pathogens

scientific article published on 28 November 2011

Manipulation of kinase signaling by bacterial pathogens is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1083/JCB.201107132
P932PMC publication ID3246894
P698PubMed publication ID22123833
P5875ResearchGate publication ID51832992

P50authorKim OrthQ49165412
Anne Marie KrachlerQ59695919
P2093author name stringAndrew R Woolery
P2860cites workStructural requirements for Yersinia YopJ inhibition of MAP kinase pathwaysQ21562307
A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory responseQ22001534
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaBQ22010046
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB functionQ24293521
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7Q24297066
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulationQ24301668
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14Q24303450
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinaseQ24314398
The protein kinase complement of the human genomeQ24324497
Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptorQ24597241
Host adhesive activities and virulence of novel fimbrial proteins of Porphyromonas gingivalisQ24644832
Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseasesQ24647287
Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense functionQ24652536
The assembly of a GTPase–kinase signalling complex by a bacterial catalytic scaffoldQ27666353
Structural and Functional Studies Indicate That the EPEC Effector, EspG, Directly Binds p21-Activated KinaseQ27666581
Metalloprotease type III effectors that specifically cleave JNK and NF-κBQ28116010
A human homologue of the Drosophila Toll protein signals activation of adaptive immunityQ28131769
Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effectorQ28144477
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factorQ28269030
TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alphaQ28287007
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adultsQ28289939
Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3Q28298554
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.Q28344579
RNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalizationQ28472290
Cytoplasmic localization of the mitogen-activated protein kinase activator MEKQ28609141
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathwayQ28615591
Gut inflammation provides a respiratory electron acceptor for SalmonellaQ29615318
Decoding the patterns of self and nonself by the innate immune systemQ29618448
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.Q30194078
???Q24601358
Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulationQ33274199
Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA.Q33506613
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infectionQ33733678
The induction of apoptosis by bacterial pathogensQ33765932
Eukaryotic signaling pathways targeted by Salmonella effector protein AvrA in intestinal infection in vivoQ33779590
NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelAQ33780981
Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesionsQ33886658
Rho GTPases as targets of bacterial protein toxinsQ33999593
YopJ of Yersinia spp. is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cellsQ34000271
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymesQ34048081
Heterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxinQ34100366
Binding to Na(+) /H(+) exchanger regulatory factor 2 (NHERF2) affects trafficking and function of the enteropathogenic Escherichia coli type III secretion system effectors Map, EspI and NleH.Q34462401
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylationQ34530978
Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signalingQ34583187
OspE2 of Shigella sonnei is required for the maintenance of cell architecture of bacterium-infected cells.Q34602029
Eliminylation: a post-translational modification catalyzed by phosphothreonine lyasesQ34949721
A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradationQ35228516
Listeria monocytogenes and listeric infectionsQ35538827
Subversion of membrane transport pathways by vacuolar pathogensQ35621027
Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membraneQ36118093
Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopHQ36375507
Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors.Q36759549
Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathwaysQ36874586
Treatment for chronic myelogenous leukemia: the long road to imatinibQ36900105
Manipulation of host-cell pathways by bacterial pathogensQ36974212
Inhibition of phagocytosis in Yersinia pseudotuberculosis: a virulence plasmid-encoded ability involving the Yop2b proteinQ36998408
Mimicking small G-proteins: an emerging theme from the bacterial virulence arsenalQ37055281
A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitorsQ37310577
Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinantQ37397346
Protein kinase B (PKB/Akt), a key mediator of the PI3K signaling pathwayQ37762205
Requirement for NF-kappaB in transcriptional activation of monocyte chemotactic protein 1 by Chlamydia pneumoniae in human endothelial cellsQ37876249
Manipulation of host membranes by bacterial effectorsQ37902048
Pathogens and polymers: microbe-host interactions illuminate the cytoskeletonQ37942128
Cell death and infection: a double-edged sword for host and pathogen survival.Q37962256
Shigella flexneri type III secreted effector OspF reveals new crosstalks of proinflammatory signaling pathways during bacterial infectionQ39576350
Inhibition of NF-κB Signaling in Human Dendritic Cells by the Enteropathogenic Escherichia coli Effector Protein NleEQ39656775
Subsite specificity of anthrax lethal factor and its implications for inhibitor developmentQ39772843
Cell invasion of Yersinia pseudotuberculosis by invasin and YadA requires protein kinase C, phospholipase C-gamma1 and Akt kinaseQ39812622
VopA inhibits ATP binding by acetylating the catalytic loop of MAPK kinasesQ40078330
The phosphothreonine lyase activity of a bacterial type III effector familyQ40170436
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responsesQ40198172
Mycobacterium tuberculosis 19-kDa lipoprotein inhibits IFN-gamma-induced chromatin remodeling of MHC2TA by TLR2 and MAPK signalingQ40302381
Interaction between the Yersinia tyrosine phosphatase YopH and its macrophage substrate, Fyn-binding protein, Fyb.Q40328925
Inhibition of MAPK signaling pathways by VopA from Vibrio parahaemolyticusQ40508871
Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway.Q40705607
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibitionQ40707709
Nuclear factor-kappa B directs carcinoembryonic antigen-related cellular adhesion molecule 1 receptor expression in Neisseria gonorrhoeae-infected epithelial cellsQ40761794
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease.Q40840610
Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophagesQ41016601
YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK.Q41052175
Inhibition of NF-kappaB/Rel induces apoptosis of murine B cellsQ41077008
Disruption of target cell adhesion structures by the Yersinia effector YopH requires interaction with the substrate domain of p130CasQ41458321
Protein tyrosine phosphatase activity of an essential virulence determinant in YersiniaQ41511214
Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakageQ41867870
Mycobacteria exploit p38 signaling to affect CD1 expression and lipid antigen presentation by human dendritic cellsQ41882089
The type III secretion effector NleE inhibits NF-kappaB activationQ41893338
Structure-based design of a heptavalent anthrax toxin inhibitor.Q42734569
Shigella effector IpaH9.8 binds to a splicing factor U2AF(35) to modulate host immune responsesQ44053369
Salmonella AvrA Coordinates Suppression of Host Immune and Apoptotic Defenses via JNK Pathway BlockadeQ44884016
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.Q45986472
AopP, a type III effector protein of Aeromonas salmonicida, inhibits the NF-kappaB signalling pathwayQ48084987
When Shigella tells the cell to hang on.Q50053392
Type III secretion effectors of the IpaH family are E3 ubiquitin ligasesQ50066742
Macrophage activation for tumor cytotoxicity: control of macrophage tumoricidal capacity by the LPS geneQ67368990
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectsignal transductionQ828130
enzymeQ8047
bacteriaQ10876
P304page(s)1083-1092
P577publication date2011-11-28
2011-12-26
P1433published inJournal of Cell BiologyQ1524550
P1476titleManipulation of kinase signaling by bacterial pathogens
P478volume195

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