NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA

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NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1001231
P932PMC publication ID3002990
P698PubMed publication ID21187904
P5875ResearchGate publication ID49711380

P2093author name stringTadasuke Ooka
Tetsuya Hayashi
Toru Tobe
Hilo Yen
Atsushi Iguchi
Nakaba Sugimoto
P2860cites workBacterial effector binding to ribosomal protein s3 subverts NF-kappaB functionQ24293521
Toll-like receptor signallingQ24570126
An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their disseminationQ24678382
Regulation and function of IKK and IKK-related kinasesQ28268930
The two NF-kappaB activation pathways and their role in innate and adaptive immunityQ29614355
Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coliQ29615309
The family of five: TIR-domain-containing adaptors in Toll-like receptor signallingQ29615457
Pathogenic Escherichia coliQ29616738
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanismQ29619866
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.Q33582255
A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cellsQ33834748
Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structureQ33944789
War and peace at mucosal surfacesQ33983437
Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formationQ34022530
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymesQ34048081
Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.Q34285636
Families of zinc metalloproteases.Q34325403
Diarrhoeagenic Escherichia coli--an emerging problem?Q34466495
Essential role of the type III secretion system effector NleB in colonization of mice by Citrobacter rodentiumQ34492843
The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleusQ34543723
The effector repertoire of enteropathogenic E. coli: ganging up on the host cellQ34921824
Phosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal eliminationQ34959023
Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophilsQ35527637
Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocationQ36104202
Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IkappaBalpha and enhances HIV-1 replication in human T lymphocytesQ37074306
Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines.Q37106331
Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coliQ37394514
Chlamydial CT441 is a PDZ domain-containing tail-specific protease that interferes with the NF-kappaB pathway of immune responseQ37859424
Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function.Q40153854
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responsesQ40198172
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradationQ40328896
Characterization of two non-locus of enterocyte effacement-encoded type III-translocated effectors, NleC and NleD, in attaching and effacing pathogensQ40380291
Actin accumulation at sites of bacterial adhesion to tissue culture cells: basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coliQ40426825
Intestinal inflammation: a complex interplay of immune and nonimmune cell interactionsQ41633390
Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69.Q41823804
The type III secretion effector NleE inhibits NF-kappaB activationQ41893338
Systematic identification and sequence analysis of the genomic islands of the enteropathogenic Escherichia coli strain B171-8 by the combined use of whole-genome PCR scanning and fosmid mappingQ42227031
Suppression of NF-kappa B activation and proinflammatory cytokine expression by Shiga toxin-producing Escherichia coliQ42436813
Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.Q42645426
A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.Q54574143
Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungiQ62090223
SOCS-1 participates in negative regulation of LPS responsesQ78518680
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue12
P921main subjectNF-κBQ411114
P304page(s)e1001231
P577publication date2010-12-16
P1433published inPLOS PathogensQ283209
P1476titleNleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA
P478volume6

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cites work (P2860)
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