Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation

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Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.0030021
P932PMC publication ID1797620
P698PubMed publication ID17305427
P5875ResearchGate publication ID6500977

P2093author name stringMichael N Starnbach
Cammie F Lesser
Ngozi A Eze
Roger W Kramer
Kara S Giddings
Keri A Siggers
Monica F Morrison
Naomi L Slagowski
P2860cites workCell wall assembly in Saccharomyces cerevisiaeQ24549234
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Pathogen recognition and innate immunityQ27861084
MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiationQ27933379
Global mapping of the yeast genetic interaction networkQ27934987
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Regulation of the yeast Rlm1 transcription factor by the Mpk1 cell wall integrity MAP kinase.Q27936197
The RIM101 pathway contributes to yeast cell wall assembly and its function becomes essential in the absence of mitogen-activated protein kinase Slt2pQ27939160
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotesQ28238338
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factorQ28269030
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.Q28344579
Flagellin induces innate immunity in nonhost interactions that is suppressed by Pseudomonas syringae effectorsQ28492432
Biochemical and genetic analysis of the yeast proteome with a movable ORF collectionQ29619667
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Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathwaysQ30885679
A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm systemQ33214421
Type III secretion machines: bacterial devices for protein delivery into host cellsQ33639326
GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structureQ33904931
Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane traffickingQ33935172
Cell wall integrity signaling in Saccharomyces cerevisiaeQ33939988
The yeast cell wall and septum as paradigms of cell growth and morphogenesisQ33942954
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymesQ34048081
Expression of microbial virulence proteins in Saccharomyces cerevisiae models mammalian infectionQ34079370
Shigella flexneri Interactions with the Basolateral Membrane Domain of Polarized Model Intestinal Epithelium: Role of Lipopolysaccharide in Cell Invasion and in Activation of the Mitogen-Activated Protein Kinase ERKQ34120536
Control of Bro1-domain protein Rim20 localization by external pH, ESCRT machinery, and the Saccharomyces cerevisiae Rim101 pathwayQ34407330
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylationQ34530978
OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulenceQ35073836
The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU.Q35107685
Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection.Q35411990
Modeling the function of bacterial virulence factors in Saccharomyces cerevisiaeQ35859746
Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulationQ37007773
The obligate intracellular pathogen Chlamydia trachomatis targets host lipid droplets.Q37861620
Characterizing gene sets with FuncAssociateQ38522379
AKR1 encodes a candidate effector of the G beta gamma complex in the Saccharomyces cerevisiae pheromone response pathway and contributes to control of both cell shape and signal transductionQ40018902
Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathwayQ40022092
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responsesQ40198172
Identification of a bacterial type III effector family with G protein mimicry functions.Q40329601
Gene function prediction from congruent synthetic lethal interactions in yeastQ40510088
The SLT2(MPK1) MAP kinase is activated during periods of polarized cell growth in yeast.Q41063523
ShiA abrogates the innate T-cell response to Shigella flexneri infectionQ42079929
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneriQ42638971
Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epitheliumQ43982547
Shigella effector IpaH9.8 binds to a splicing factor U2AF(35) to modulate host immune responsesQ44053369
Modular epistasis in yeast metabolism.Q51982575
A new method for quantitative determination of polysaccharides in the yeast cell wall. Application to the cell wall defective mutants of Saccharomyces cerevisiaeQ77512042
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesaffyQ113334509
P433issue2
P921main subjectfunctional genomicsQ1068690
P304page(s)e21
P577publication date2007-02-01
P1433published inPLOS PathogensQ283209
P1476titleYeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation
P478volume3

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